Homo sapiens (human): 130399 Help Entry 130399            CDS       T01001                                  Symbol ACVR1C, ACVRLK7, ALK7 Name (RefSeq) activin A receptor type 1C   KO K13568   activin receptor type-1C [EC:2.7.11.30] Organism hsa  Homo sapiens (human) Pathway hsa04060   Cytokine-cytokine receptor interaction hsa04350   TGF-beta signaling pathway hsa04550   Signaling pathways regulating pluripotency of stem cells Network nt06507  TGFB signaling   Element N01456   Activin signaling pathway N01459   Nodal signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04350 TGF-beta signaling pathway     130399 (ACVR1C)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     130399 (ACVR1C)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     130399 (ACVR1C)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     130399 (ACVR1C) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.30  receptor protein serine/threonine kinase      130399 (ACVR1C) Protein kinases [BR:hsa01001]  Receptor serine/threonine kinases (RSTK): TKL group   TGFBR1 family [OT]    130399 (ACVR1C) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase TGF_beta_GS Activin_recp Pkinase_fungal Motif Other DBs NCBI-GeneID:  130399 NCBI-ProteinID:  NP_660302 OMIM:  608981 HGNC:  18123 Ensembl:  ENSG00000123612 UniProt:  Q8NER5 LinkDB All DBs Position 2:complement(157526767..157628864) Genome browser AA seq 493 aa AA seqDB search MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVI KSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPMELAIIITV PVCLLSIAAMLTVWACQGRQCSYRKKKRPNVEEPLSECNLVNAGKTLKDLIYDVTASGSG SGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQ TVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIA SGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQN PKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYD MVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKK TISQLCVKEDCKA NT seq 1482 nt NT seq  +upstreamnt  +downstreamnt atgacccgggcgctctgctcagcgctccgccaggctctcctgctgctcgcagcggccgcc gagctctcgccaggactgaagtgtgtatgtcttttgtgtgattcttcaaacttcacctgc caaacagaaggagcatgttgggcatcagtcatgctaaccaatggaaaagagcaggtgatc aaatcctgtgtctcccttccagaactgaatgctcaagtcttctgtcatagttccaacaat gttaccaaaaccgaatgctgcttcacagatttttgcaacaacataacactgcaccttcca acagcatcaccaaatgccccaaaacttggacccatggagctggccatcattattactgtg cctgtttgcctcctgtccatagctgcgatgctgacagtatgggcatgccagggtcgacag tgctcctacaggaagaaaaagagaccaaatgtggaggaaccactctctgagtgcaatctg gtaaatgctggaaaaactctgaaagatctgatttatgatgtgaccgcctctggatctggc tctggtctacctctgttggttcaaaggacaattgcaaggacgattgtgcttcaggaaata gtaggaaaaggtagatttggtgaggtgtggcatggaagatggtgtggggaagatgtggct gtgaaaatattctcctccagagatgaaagatcttggtttcgtgaggcagaaatttaccag acggtcatgctgcgacatgaaaacatccttggtttcattgctgctgacaacaaagataat ggaacttggactcaactttggctggtatctgaatatcatgaacagggctccttatatgac tatttgaatagaaatatagtgaccgtggctggaatgatcaagctggcgctctcaattgct agtggtctggcacaccttcatatggagattgttggtacacaaggtaaacctgctattgct catcgagacataaaatcaaagaatatcttagtgaaaaagtgtgaaacttgtgccatagcg gacttagggttggctgtgaagcatgattcaatactgaacactatcgacatacctcagaat cctaaagtgggaaccaagaggtatatggctcctgaaatgcttgatgatacaatgaatgtg aatatctttgagtccttcaaacgagctgacatctattctgttggtctggtttactgggaa atagcccggaggtgttcagtcggaggaattgttgaggagtaccaattgccttattatgac atggtgccttcagatccctcgatagaggaaatgagaaaggttgtttgtgaccagaagttt cgaccaagtatcccaaaccagtggcaaagttgtgaagcactccgagtcatggggagaata atgcgtgagtgttggtatgccaacggagcggcccgcctaactgctcttcgtattaagaag actatatctcaactttgtgtcaaagaagactgcaaagcctaa

Homo sapiens (human): 91 Help Entry 91                CDS       T01001                                  Symbol ACVR1B, ACTRIB, ACVRLK4, ALK4, SKR2 Name (RefSeq) activin A receptor type 1B   KO K13567   activin receptor type-1B [EC:2.7.11.30] Organism hsa  Homo sapiens (human) Pathway hsa04060   Cytokine-cytokine receptor interaction hsa04350   TGF-beta signaling pathway hsa04550   Signaling pathways regulating pluripotency of stem cells Network nt06507  TGFB signaling   Element N01456   Activin signaling pathway N01457   Myostatin signaling pathway N01459   Nodal signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04350 TGF-beta signaling pathway     91 (ACVR1B)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     91 (ACVR1B)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     91 (ACVR1B)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     91 (ACVR1B) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.30  receptor protein serine/threonine kinase      91 (ACVR1B) Protein kinases [BR:hsa01001]  Receptor serine/threonine kinases (RSTK): TKL group   TGFBR1 family [OT]    91 (ACVR1B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp APH Pkinase_fungal FTA2 Motif Other DBs NCBI-GeneID:  91 NCBI-ProteinID:  NP_004293 OMIM:  601300 HGNC:  172 Ensembl:  ENSG00000135503 UniProt:  P36896 Structure PDB LinkDB All DBs Position 12:51951699..51997078 Genome browser AA seq 505 aa AA seqDB search MAESAGASSFFPLVVLLLAGSGGSGPRGVQALLCACTSCLQANYTCETDGACMVSIFNLD GMEHHVRTCIPKVELVPAGKPFYCLSSEDLRNTHCCYTDYCNRIDLRVPSGHLKEPEHPS MWGPVELVGIIAGPVFLLFLIIIIVFLVINYHQRVYHNRQRLDMEDPSCEMCLSKDKTLQ DLVYDLSTSGSGSGLPLFVQRTVARTIVLQEIIGKGRFGEVWRGRWRGGDVAVKIFSSRE ERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVT IEGMIKLALSAASGLAHLHMEIVGTQGKPGIAHRDLKSKNILVKKNGMCAIADLGLAVRH DAVTDTIDIAPNQRVGTKRYMAPEVLDETINMKHFDSFKCADIYALGLVYWEIARRCNSG GVHEEYQLPYYDLVPSDPSIEEMRKVVCDQKLRPNIPNWWQSYEALRVMGKMMRECWYAN GAARLTALRIKKTLSQLSVQEDVKI NT seq 1518 nt NT seq  +upstreamnt  +downstreamnt atggcggagtcggccggagcctcctccttcttcccccttgttgtcctcctgctcgccggc agcggcgggtccgggccccggggggtccaggctctgctgtgtgcgtgcaccagctgcctc caggccaactacacgtgtgagacagatggggcctgcatggtttccattttcaatctggat gggatggagcaccatgtgcgcacctgcatccccaaagtggagctggtccctgccgggaag cccttctactgcctgagctcggaggacctgcgcaacacccactgctgctacactgactac tgcaacaggatcgacttgagggtgcccagtggtcacctcaaggagcctgagcacccgtcc atgtggggcccggtggagctggtaggcatcatcgccggcccggtgttcctcctgttcctc atcatcatcattgttttccttgtcattaactatcatcagcgtgtctatcacaaccgccag agactggacatggaagatccctcatgtgagatgtgtctctccaaagacaagacgctccag gatcttgtctacgatctctccacctcagggtctggctcagggttacccctctttgtccag cgcacagtggcccgaaccatcgttttacaagagattattggcaagggtcggtttggggaa gtatggcggggccgctggaggggtggtgatgtggctgtgaaaatattctcttctcgtgaa gaacggtcttggttcagggaagcagagatataccagacggtcatgctgcgccatgaaaac atccttggatttattgctgctgacaataaagataatggcacctggacacagctgtggctt gtttctgactatcatgagcacgggtccctgtttgattatctgaaccggtacacagtgaca attgaggggatgattaagctggccttgtctgctgctagtgggctggcacacctgcacatg gagatcgtgggcacccaagggaagcctggaattgctcatcgagacttaaagtcaaagaac attctggtgaagaaaaatggcatgtgtgccatagcagacctgggcctggctgtccgtcat gatgcagtcactgacaccattgacattgccccgaatcagagggtggggaccaaacgatac atggcccctgaagtacttgatgaaaccattaatatgaaacactttgactcctttaaatgt gctgatatttatgccctcgggcttgtatattgggagattgctcgaagatgcaattctgga ggagtccatgaagaatatcagctgccatattacgacttagtgccctctgacccttccatt gaggaaatgcgaaaggttgtatgtgatcagaagctgcgtcccaacatccccaactggtgg cagagttatgaggcactgcgggtgatggggaagatgatgcgagagtgttggtatgccaac ggcgcagcccgcctgacggccctgcgcatcaagaagaccctctcccagctcagcgtgcag gaagacgtgaagatctaa

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