Homo sapiens (human): 131890 Help Entry 131890            CDS       T01001                                  Symbol GRK7, GPRK7 Name (RefSeq) G protein-coupled receptor kinase 7   KO K00909   rhodopsin kinase [EC:2.7.11.14] Organism hsa  Homo sapiens (human) Pathway hsa04062   Chemokine signaling pathway hsa04144   Endocytosis hsa04744   Phototransduction Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     131890 (GRK7)  09150 Organismal Systems   09151 Immune system    04062 Chemokine signaling pathway     131890 (GRK7)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     131890 (GRK7) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.14  rhodopsin kinase      131890 (GRK7) Protein kinases [BR:hsa01001]  Serine/threonine kinases: AGC group   GRK family [OT]    131890 (GRK7) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr RGS Kinase-like Pkinase_fungal Motif Other DBs NCBI-GeneID:  131890 NCBI-ProteinID:  NP_631948 OMIM:  606987 HGNC:  17031 Ensembl:  ENSG00000114124 UniProt:  Q8WTQ7 LinkDB All DBs Position 3:141749984..141819352 Genome browser AA seq 553 aa AA seqDB search MVDMGALDNLIANTAYLQARKPSDCDSKELQRRRRSLALPGLQGCAELRQKLSLNFHSLC EQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAPG NPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWKL FEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEK EILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQI ACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPE ILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFT EEAKDICRLFLAKKPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYA KDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPTGCE EGNSSKSGVCLLL NT seq 1662 nt NT seq  +upstreamnt  +downstreamnt atggtggacatgggggccctggacaacctgatcgccaacaccgcctacctgcaggcccgg aagccctcggactgcgacagcaaagagctgcagcggcggcggcgtagcctggccctgccc gggctgcagggctgcgcggagctccgccagaagctgtccctgaacttccacagcctgtgt gagcagcagcccatcggtcgccgcctcttccgtgacttcctagccacagtgcccacgttc cgcaaggcggcaaccttcctagaggacgtgcagaactgggagctggccgaggagggaccc accaaagacagcgcgctgcaggggctggtggccacttgtgcgagtgcccctgccccgggg aacccgcaacccttcctcagccaggccgtggccaccaagtgccaagcagccaccactgag gaagagcgagtggctgcagtgacgctggccaaggctgaggccatggctttcttgcaagag cagccctttaaggatttcgtgaccagcgccttctacgacaagtttctgcagtggaaactc ttcgagatgcaaccagtgtcagacaagtacttcactgagttcagagtgctggggaaaggt ggttttggggaggtatgtgccgtccaggtgaaaaacactgggaagatgtatgcctgtaag aaactggacaagaagcggctgaagaagaaaggtggcgagaagatggctctcttggaaaag gaaatcttggagaaggtcagcagccctttcattgtctctctggcctatgcctttgagagc aagacccatctctgccttgtcatgagcctgatgaatgggggagacctcaagttccacatc tacaacgtgggcacgcgtggcctggacatgagccgggtgatcttttactcggcccagata gcctgtgggatgctgcacctccatgaactcggcatcgtctatcgggacatgaagcctgag aatgtgcttctggatgacctcggcaactgcaggttatctgacctggggctggccgtggag atgaagggtggcaagcccatcacccagagggctggaaccaatggttacatggctcctgag atcctaatggaaaaggtaagttattcctatcctgtggactggtttgccatgggatgcagc atttatgaaatggttgctggacgaacaccattcaaagattacaaggaaaaggtcagtaaa gaggatctgaagcaaagaactctgcaagacgaggtcaaattccagcatgataacttcaca gaggaagcaaaagatatttgcaggctcttcttggctaagaaaccagagcaacgcttagga agcagagaaaagtctgatgatcccaggaaacatcatttctttaaaacgatcaactttcct cgcctggaagctggcctaattgaacccccatttgtgccagacccttcagtggtttatgcc aaagacatcgctgaaattgatgatttctctgaggttcggggggtggaatttgatgacaaa gataagcagttcttcaaaaactttgcgacaggtgctgttcctatagcatggcaggaagaa attatagaaacgggactgtttgaggaactgaatgaccccaacagacctacgggttgtgag gagggtaattcatccaagtctggcgtgtgtttgttattgtaa

Homo sapiens (human): 156 Help Entry 156               CDS       T01001                                  Symbol GRK2, ADRBK1, BARK1, BETA-ARK1 Name (RefSeq) G protein-coupled receptor kinase 2   KO K00910   beta-adrenergic-receptor kinase [EC:2.7.11.15] Organism hsa  Homo sapiens (human) Pathway hsa04062   Chemokine signaling pathway hsa04144   Endocytosis hsa04340   Hedgehog signaling pathway hsa04724   Glutamatergic synapse hsa04740   Olfactory transduction hsa05032   Morphine addiction Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     156 (GRK2)  09150 Organismal Systems   09151 Immune system    04062 Chemokine signaling pathway     156 (GRK2)   09156 Nervous system    04724 Glutamatergic synapse     156 (GRK2)   09157 Sensory system    04740 Olfactory transduction     156 (GRK2)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     156 (GRK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     156 (GRK2)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     156 (GRK2) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.15  beta-adrenergic-receptor kinase      156 (GRK2) Protein kinases [BR:hsa01001]  Serine/threonine kinases: AGC group   GRK family [OT]    156 (GRK2) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    156 (GRK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr RGS PH Kinase-like Haspin_kinase DUF5647 HTH_WhiA Motif Other DBs NCBI-GeneID:  156 NCBI-ProteinID:  NP_001610 OMIM:  109635 HGNC:  289 Ensembl:  ENSG00000173020 UniProt:  P25098 A0A0S2Z392 Structure PDBPDBj LinkDB All DBs Position 11:67266473..67286556 Genome browser AA seq 689 aa AA seqDB search MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS QKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLAC SHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE LRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA DAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARK KAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSL LTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQR VPKMKNKPRSPVVELSKVPLVQRGSANGL NT seq 2070 nt NT seq  +upstreamnt  +downstreamnt atggcggacctggaggcggtgctggccgacgtgagctacctgatggccatggagaagagc aaggccacgccggccgcgcgcgccagcaagaagatcctgctgcccgagcccagcatccgc agtgtcatgcagaagtacctggaggaccggggcgaggtgacctttgagaagatcttttcc cagaagctggggtacctgctcttccgagacttctgcctgaaccacctggaggaggccagg cccttggtggaattctatgaggagatcaagaagtacgagaagctggagacggaggaggag cgtgtggcccgcagccgggagatcttcgactcatacatcatgaaggagctgctggcctgc tcgcatcccttctcgaagagtgccactgagcatgtccaaggccacctggggaagaagcag gtgcctccggatctcttccagccatacatcgaagagatttgtcaaaacctccgaggggac gtgttccagaaattcattgagagcgataagttcacacggttttgccagtggaagaatgtg gagctcaacatccacctgaccatgaatgacttcagcgtgcatcgcatcattgggcgcggg ggctttggcgaggtctatgggtgccggaaggctgacacaggcaagatgtacgccatgaag tgcctggacaaaaagcgcatcaagatgaagcagggggagaccctggccctgaacgagcgc atcatgctctcgctcgtcagcactggggactgcccattcattgtctgcatgtcatacgcg ttccacacgccagacaagctcagcttcatcctggacctcatgaacggtggggacctgcac taccacctctcccagcacggggtcttctcagaggctgacatgcgcttctatgcggccgag atcatcctgggcctggagcacatgcacaaccgcttcgtggtctaccgggacctgaagcca gccaacatccttctggacgagcatggccacgtgcggatctcggacctgggcctggcctgt gacttctccaagaagaagccccatgccagcgtgggcacccacgggtacatggctccggag gtcctgcagaagggcgtggcctacgacagcagtgccgactggttctctctggggtgcatg ctcttcaagttgctgcgggggcacagccccttccggcagcacaagaccaaagacaagcat gagatcgaccgcatgacgctgacgatggccgtggagctgcccgactccttctcccctgaa ctacgctccctgctggaggggttgctgcagagggatgtcaaccggagattgggctgcctg ggccgaggggctcaggaggtgaaagagagcccctttttccgctccctggactggcagatg gtcttcttgcagaagtaccctcccccgctgatccccccacgaggggaggtgaacgcggcc gacgccttcgacattggctccttcgatgaggaggacacaaaaggaatcaagttactggac agtgatcaggagctctaccgcaacttccccctcaccatctcggagcggtggcagcaggag gtggcagagactgtcttcgacaccatcaacgctgagacagaccggctggaggctcgcaag aaagccaagaacaagcagctgggccatgaggaagactacgccctgggcaaggactgcatc atgcatggctacatgtccaagatgggcaaccccttcctgacccagtggcagcggcggtac ttctacctgttccccaaccgcctcgagtggcggggcgagggcgaggccccgcagagcctg ctgaccatggaggagatccagtcggtggaggagacgcagatcaaggagcgcaagtgcctg ctcctcaagatccgcggtgggaaacagttcattttgcagtgcgatagcgaccctgagctg gtgcagtggaagaaggagctgcgcgacgcctaccgcgaggcccagcagctggtgcagcgg gtgcccaagatgaagaacaagccgcgctcgcccgtggtggagctgagcaaggtgccgctg gtccagcgcggcagtgccaacggcctctga

Homo sapiens (human): 157 Help Entry 157               CDS       T01001                                  Symbol GRK3, ADRBK2, BARK2 Name (RefSeq) G protein-coupled receptor kinase 3   KO K00910   beta-adrenergic-receptor kinase [EC:2.7.11.15] Organism hsa  Homo sapiens (human) Pathway hsa04062   Chemokine signaling pathway hsa04144   Endocytosis hsa04340   Hedgehog signaling pathway hsa04724   Glutamatergic synapse hsa04740   Olfactory transduction hsa05032   Morphine addiction Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     157 (GRK3)  09150 Organismal Systems   09151 Immune system    04062 Chemokine signaling pathway     157 (GRK3)   09156 Nervous system    04724 Glutamatergic synapse     157 (GRK3)   09157 Sensory system    04740 Olfactory transduction     157 (GRK3)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     157 (GRK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     157 (GRK3)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     157 (GRK3) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.15  beta-adrenergic-receptor kinase      157 (GRK3) Protein kinases [BR:hsa01001]  Serine/threonine kinases: AGC group   GRK family [OT]    157 (GRK3) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    157 (GRK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr RGS PH HTH_WhiA Kinase-like Motif Other DBs NCBI-GeneID:  157 NCBI-ProteinID:  NP_005151 OMIM:  109636 HGNC:  290 Ensembl:  ENSG00000100077 UniProt:  P35626 Q8N433 LinkDB All DBs Position 22:25564675..25729294 Genome browser AA seq 688 aa AA seqDB search MADLEAVLADVSYLMAMEKSKATPAARASKRIVLPEPSIRSVMQKYLAERNEITFDKIFN QKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSC SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNV ELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGVFSEKEMRFYATE IILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKPHASVGTHGYMAPE VLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVELPDTFSPE LKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGEVNAA DAFDIGSFDEEDTKGIKLLDCDQELYKNFPLVISERWQQEVTETVYEAVNADTDKIEARK RAKNKQLGHEEDYALGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQNL LTMEQILSVEETQIKDKKCILFRIKGGKQFVLQCESDPEFVQWKKELNETFKEAQRLLRR APKFLNKPRSGTVELPKPSLCHRNSNGL NT seq 2067 nt NT seq  +upstreamnt  +downstreamnt atggcggacctggaggctgtgctggccgatgtcagttacctgatggccatggagaagagc aaggcgaccccggccgcccgcgccagcaagaggatcgtcctgccggagcccagtatccgg agtgtgatgcagaagtaccttgcagagagaaatgaaataacctttgacaagattttcaat cagaaaattggtttcttgctatttaaagatttttgtttgaatgaaattaatgaagctgta cctcaggtgaagttttatgaagagataaaggaatatgaaaaacttgataatgaggaagac cgcctttgcagaagtcgacaaatttatgatgcctacatcatgaaggaacttctttcctgt tcacatcctttctcaaagcaagctgtagaacacgtacaaagtcatttatccaagaaacaa gtgacatcaactctttttcagccatacatagaagaaatttgtgaaagccttcgaggtgac atttttcaaaaatttatggaaagtgacaagttcactagattttgtcagtggaaaaacgtt gaattaaatatccatttgaccatgaatgagttcagtgtgcataggattattggacgagga ggattcggggaagtttatggttgcaggaaagcagacactggaaaaatgtatgcaatgaaa tgcttagataagaagaggatcaaaatgaaacaaggagaaacattagccttaaatgaaaga atcatgttgtctcttgtcagcacaggagactgtcctttcattgtatgtatgacctatgcc ttccataccccagataaactctgcttcatcctggatctgatgaacgggggcgatttgcac taccacctttcacaacacggtgtgttctctgagaaggagatgcggttttatgccactgaa atcattctgggtctggaacacatgcacaatcggtttgttgtctacagagatttgaagcca gcaaatattctcttggatgaacatggacacgcaagaatatcagatcttggtcttgcctgc gatttttccaaaaagaagcctcatgcgagtgttggcacccatgggtacatggctcccgag gtgctgcagaaggggacggcctatgacagcagtgccgactggttctccctgggctgcatg cttttcaaacttctgagaggtcacagccctttcagacaacataaaaccaaagacaagcat gaaattgaccgaatgacactcaccgtgaatgtggaacttccagacaccttctctcctgaa ctgaagtcccttttggagggcttgcttcagcgagacgttagcaagcggctgggctgtcac ggaggcggctcacaggaagtaaaagagcacagctttttcaaaggtgttgactggcagcat gtctacttacaaaagtacccaccacccttgattcctccccggggagaagtcaatgctgct gatgcctttgatattggctcatttgatgaagaggataccaaagggattaagctacttgat tgcgaccaagaactctacaagaacttccctttggtcatctctgaacgctggcagcaagaa gtaacggaaacagtttatgaagcagtaaatgcagacacagataaaatcgaggccaggaag agagctaaaaataagcaacttggccacgaagaagattacgctctggggaaggactgtatt atgcacgggtacatgctgaaactgggaaacccatttctgactcagtggcagcgtcgctat ttttacctctttccaaatagacttgaatggagaggagagggagagtcccggcaaaattta ctgacaatggaacagattctctctgtggaagaaactcaaattaaagacaaaaaatgcatt ttgttcagaataaaaggagggaaacaatttgtcttgcaatgtgagagtgatccagagttt gtgcagtggaagaaagagttgaacgaaaccttcaaggaggcccagcggctattgcgtcgt gccccgaagttcctcaacaaacctcggtcaggtactgtggagctcccaaagccatccctc tgtcacagaaacagcaacggcctctag

Homo sapiens (human): 2868 Help Entry 2868              CDS       T01001                                  Symbol GRK4, GPRK2L, GPRK4, GRK4a, IT11 Name (RefSeq) G protein-coupled receptor kinase 4   KO K08291   G protein-coupled receptor kinase [EC:2.7.11.16] Organism hsa  Homo sapiens (human) Pathway hsa04062   Chemokine signaling pathway hsa04144   Endocytosis hsa05032   Morphine addiction Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     2868 (GRK4)  09150 Organismal Systems   09151 Immune system    04062 Chemokine signaling pathway     2868 (GRK4)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2868 (GRK4)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     2868 (GRK4) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.16  G-protein-coupled receptor kinase      2868 (GRK4) Protein kinases [BR:hsa01001]  Serine/threonine kinases: AGC group   GRK family [OT]    2868 (GRK4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr RGS Kinase-like Pkinase_fungal ABC1 Motif Other DBs NCBI-GeneID:  2868 NCBI-ProteinID:  NP_892027 OMIM:  137026 HGNC:  4543 Ensembl:  ENSG00000125388 UniProt:  P32298 Structure PDBPDBj LinkDB All DBs Position 4:2963571..3040760 Genome browser AA seq 578 aa AA seqDB search MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQ PIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPE IPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQ PVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILE KVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGL EDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNN EKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSI CRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLD IEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINKSESEEALPLDLDK NIHTPVSRPNRGFFYRLFRRGGCLTMVPSEKEVEPKQC NT seq 1737 nt NT seq  +upstreamnt  +downstreamnt atggagctcgagaacatcgtggccaactcgctgctgctgaaagcgcgtcaaggaggatat ggcaaaaaaagtggtcgtagtaaaaaatggaaggagatactgacactgcctcctgtcagc cagtgcagtgagcttagacattccattgaaaaggattatagcagtctttgtgacaagcaa ccgataggaagacgtctcttcaggcagttctgtgataccaaacccactctaaagaggcac attgaattcttggatgcagtggcagaatatgaagttgccgatgatgaggaccgaagtgat tgtggactgtcaatcttagatagattcttcaatgataagttggcagcccctttaccagaa atacctccagatgttgtgacagaatgtagattgggactgaaggaggagaacccttccaaa aaagcctttgaggaatgtactagagttgcccataactacctaagaggggaaccatttgaa gaataccaagaaagctcatatttttctcagtttttacaatggaaatggctggaaaggcaa cccgtaacaaagaacacatttagacattacagagttctaggaaaaggcggatttggagag gtttgcgcctgtcaagtgcgagccacaggaaaaatgtatgcctgcaaaaagctacaaaaa aaaagaataaagaagaggaaaggtgaagctatggctctaaatgagaaaagaattctggag aaagtgcaaagtagattcgtagttagtttagcctacgcttatgaaaccaaagatgccttg tgcttggtgctcaccattatgaatggaggggatttgaagtttcacatttacaacctgggc aatcccggctttgatgagcagagagccgttttctatgctgcagagctgtgttgcggcttg gaagatttacagagggaaagaattgtatacagagacttgaagcctgagaatattctcctt gatgatcgtggacacatccggatttcagacctcggtttggccacagagatcccagaagga cagagggttcgaggaagagttggaacagtcggctacatggcacctgaagttgtcaataat gaaaagtatacgtttagtcccgattggtggggacttggctgtctgatctatgaaatgatt cagggacattctccattcaaaaaatacaaagagaaagtcaaatgggaggaggtcgatcaa agaatcaagaatgataccgaggagtattctgagaagttttcagaggatgccaaatctatc tgcaggatgttactcaccaagaatccaagcaagcggctgggctgcaggggcgagggagcg gctggggtgaagcagcaccccgtgttcaaggacatcaacttcaggaggctggaggcaaac atgctggagccccctttctgtcctgatcctcatgccgtttactgtaaggacgtcctggat atcgagcagttctcggtggtgaaagggatctacctggacaccgcagatgaagacttctat gctcggtttgctaccgggtgtgtctccatcccctggcagaatgagatgatcgaatctggg tgtttcaaagacatcaacaaaagtgaaagtgaggaagctttgccattagatctagacaag aacatacataccccggtttccagaccaaacagaggcttcttctatagactcttcagaaga gggggctgcctgaccatggtccccagtgagaaggaagtggaacccaagcaatgctga

Homo sapiens (human): 2869 Help Entry 2869              CDS       T01001                                  Symbol GRK5, FP2025, GPRK5 Name (RefSeq) G protein-coupled receptor kinase 5   KO K08291   G protein-coupled receptor kinase [EC:2.7.11.16] Organism hsa  Homo sapiens (human) Pathway hsa04062   Chemokine signaling pathway hsa04144   Endocytosis hsa05032   Morphine addiction Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     2869 (GRK5)  09150 Organismal Systems   09151 Immune system    04062 Chemokine signaling pathway     2869 (GRK5)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2869 (GRK5)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     2869 (GRK5) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.16  G-protein-coupled receptor kinase      2869 (GRK5) Protein kinases [BR:hsa01001]  Serine/threonine kinases: AGC group   GRK family [OT]    2869 (GRK5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr RGS Kinase-like Pkinase_fungal Sulfakinin Motif Other DBs NCBI-GeneID:  2869 NCBI-ProteinID:  NP_005299 OMIM:  600870 HGNC:  4544 Ensembl:  ENSG00000198873 UniProt:  P34947 Structure PDBPDBj LinkDB All DBs Position 10:119207571..119459745 Genome browser AA seq 590 aa AA seqDB search MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ VGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQP VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI EQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLNRN HPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHHINSNHVSSNSTGSS NT seq 1773 nt NT seq  +upstreamnt  +downstreamnt atggagctggaaaacatcgtggccaacacggtcttgctgaaagccagggaagggggcgga ggaaagcgcaaagggaaaagcaagaagtggaaagaaatcctgaagttccctcacattagc cagtgtgaagacctccgaaggaccatagacagagattactgcagtttatgtgacaagcag ccaatcgggaggctgcttttccggcagttttgtgaaaccaggcctgggctggagtgttac attcagttcctggactccgtggcagaatatgaagttactccagatgaaaaactgggagag aaagggaaggaaattatgaccaagtacctcaccccaaagtcccctgttttcatagcccaa gttggccaagacctggtctcccagacggaggagaagctcctacagaagccgtgcaaagaa ctcttttctgcctgtgcacagtctgtccacgagtacctgaggggagaaccattccacgaa tatctggacagcatgttttttgaccgctttctccagtggaagtggttggaaaggcaaccg gtgaccaaaaacactttcaggcagtatcgagtgctaggaaaagggggcttcggggaggtc tgtgcctgccaggttcgggccacgggtaaaatgtatgcctgcaagcgcttggagaagaag aggatcaaaaagaggaaaggggagtccatggccctcaatgagaagcagatcctcgagaag gtcaacagtcagtttgtggtcaacctggcctatgcctacgagaccaaggatgcactgtgc ttggtcctgaccatcatgaatgggggtgacctgaagttccacatctacaacatgggcaac cctggcttcgaggaggagcgggccttgttttatgcggcagagatcctctgcggcttagaa gacctccaccgtgagaacaccgtctaccgagatctgaaacctgaaaacatcctgttagat gattatggccacattaggatctcagacctgggcttggctgtgaagatccccgagggagac ctgatccgcggccgggtgggcactgttggctacatggctccagaggtcctgaacaaccag aggtacggcctgagccccgactactggggccttggctgcctcatctatgagatgatcgag ggccagtcgccgttccgcggccgcaaggagaaggtgaagcgggaggaggtggaccgccgg gtcctggagacggaggaggtgtactcccacaagttctccgaggaggccaagtccatctgc aagatgctgctcacgaaagatgcgaagcagaggctgggctgccaggaggagggggctgca gaggtcaagagacaccccttcttcaggaacatgaacttcaagcgcttagaagccgggatg ttggaccctcccttcgttccagacccccgcgctgtgtactgtaaggacgtgctggacatc gagcagttctccactgtgaagggcgtcaatctggaccacacagacgacgacttctactcc aagttctccacgggctctgtgtccatcccatggcaaaacgagatgatagaaacagaatgc tttaaggagctgaacgtgtttggacctaatggtaccctcccgccagatctgaacagaaac caccctccggaaccgcccaagaaagggctgctccagagactcttcaagcggcagcatcag aacaattccaagagttcgcccagctccaagaccagttttaaccaccacataaactcaaac catgtcagctcgaactccaccggaagcagctag

Homo sapiens (human): 2870 Help Entry 2870              CDS       T01001                                  Symbol GRK6, GPRK6 Name (RefSeq) G protein-coupled receptor kinase 6   KO K08291   G protein-coupled receptor kinase [EC:2.7.11.16] Organism hsa  Homo sapiens (human) Pathway hsa04062   Chemokine signaling pathway hsa04144   Endocytosis hsa05032   Morphine addiction Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     2870 (GRK6)  09150 Organismal Systems   09151 Immune system    04062 Chemokine signaling pathway     2870 (GRK6)  09160 Human Diseases   09165 Substance dependence    05032 Morphine addiction     2870 (GRK6)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     2870 (GRK6) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.16  G-protein-coupled receptor kinase      2870 (GRK6) Protein kinases [BR:hsa01001]  Serine/threonine kinases: AGC group   GRK family [OT]    2870 (GRK6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr RGS Kinase-like Pkinase_fungal Motif Other DBs NCBI-GeneID:  2870 NCBI-ProteinID:  NP_001004106 OMIM:  600869 HGNC:  4545 Ensembl:  ENSG00000198055 UniProt:  P43250 Structure PDBPDBj LinkDB All DBs Position 5:177425523..177442891 Genome browser AA seq 576 aa AA seqDB search MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK GQPPAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL NT seq 1731 nt NT seq  +upstreamnt  +downstreamnt atggagctcgagaacatcgtagcgaacacggtgctactcaaggcccgggaaggtggcggt ggaaatcgcaaaggcaaaagcaagaaatggcggcagatgctccagttccctcacatcagc cagtgcgaagagctgcggctcagcctcgagcgtgactatcacagcctgtgcgagcggcag cccattgggcgcctgctgttccgagagttctgtgccacgaggccggagctgagccgctgc gtcgccttcctggatggggtggccgagtatgaagtgaccccggatgacaagcggaaggca tgtgggcggcagctaacgcagaattttctgagccacacgggtcctgacctcatccctgag gtcccccggcagctggtgacgaactgcacccagcggctggagcagggtccctgcaaagac cttttccaggaactcacccggctgacccacgagtacctgagcgtggccccttttgccgac tacctcgacagcatctacttcaaccgtttcctgcagtggaagtggctggaaaggcagcca gtgaccaaaaacaccttcaggcaataccgagtcctgggcaaaggtggctttggggaggtg tgcgcctgccaggtgcgggccacaggtaagatgtatgcctgcaagaagctagagaaaaag cggatcaagaagcggaaaggggaggccatggcgctgaacgagaagcagatcctggagaaa gtgaacagtaggtttgtagtgagcttggcctacgcctatgagaccaaggacgcgctgtgc ctggtgctgacactgatgaacgggggcgacctcaagttccacatctaccacatgggccag gctggcttccccgaagcgcgggccgtcttctacgccgccgagatctgctgtggcctggag gacctgcaccgggagcgcatcgtgtacagggacctgaagcccgagaacatcttgctggat gaccacggccacatccgcatctctgacctgggactagctgtgcatgtgcccgagggccag accatcaaagggcgtgtgggcaccgtgggttacatggctccggaggtggtgaagaatgaa cggtacacgttcagccctgactggtgggcgctcggctgcctcctgtacgagatgatcgca ggccagtcgcccttccagcagaggaagaagaagatcaagcgggaggaggtggagcggctg gtgaaggaggtccccgaggagtattccgagcgcttttccccgcaggcccgctcactttgc tcacagctcctctgcaaggaccctgccgaacgcctggggtgtcgtgggggcagtgcccgc gaggtgaaggagcaccccctctttaagaagctgaacttcaagcggctgggagctggcatg ctggagccgccgttcaagcctgacccccaggccatttactgcaaggatgttctggacatt gaacagttctctacggtcaagggcgtggagctggagcctaccgaccaggacttctaccag aagtttgccacaggcagtgtgcccatcccctggcagaacgagatggtggagaccgagtgc ttccaagagctgaatgtctttgggctggatggctcagttcccccagacctggactggaag ggccagccacctgcacctcctaaaaagggactgctgcagagactcttcagtcgccaagat tgctgtggaaactgcagcgacagcgaggaagagctccccacccgcctctag

Homo sapiens (human): 6011 Help Entry 6011              CDS       T01001                                  Symbol GRK1, GPRK1, RHOK, RK Name (RefSeq) G protein-coupled receptor kinase 1   KO K00909   rhodopsin kinase [EC:2.7.11.14] Organism hsa  Homo sapiens (human) Pathway hsa04062   Chemokine signaling pathway hsa04144   Endocytosis hsa04744   Phototransduction Disease H00787   Congenital stationary night blindness Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     6011 (GRK1)  09150 Organismal Systems   09151 Immune system    04062 Chemokine signaling pathway     6011 (GRK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     6011 (GRK1) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.14  rhodopsin kinase      6011 (GRK1) Protein kinases [BR:hsa01001]  Serine/threonine kinases: AGC group   GRK family [OT]    6011 (GRK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr RGS Pkinase_fungal Kinase-like Motif Other DBs NCBI-GeneID:  6011 NCBI-ProteinID:  NP_002920 OMIM:  180381 HGNC:  10013 Ensembl:  ENSG00000185974 UniProt:  Q15835 Structure PDBPDBj LinkDB All DBs Position 13:113648199..113737736 Genome browser AA seq 563 aa AA seqDB search MDFGSLETVVANSAFIAARGSFDGSSSQPSRDKKYLAKLKLPPLSKCESLRDSLSLEFES VCLEQPIGKKLFQQFLQSAEKHLPALELWKDIEDYDTADNDLQPQKAQTILAQYLDPQAK LFCSFLDEGIVAKFKEGPVEIQDGLFQPLLQATLAHLGQAPFQEYLGSLYFLRFLQWKWL EAQPMGEDWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKK ILMKVHSRFIVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQ IICGLEHLHQRRIVYRDLKPENVLLDNDGNVRISDLGLAVELLDGQSKTKGYAGTPGFMA PELLQGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKHRIISEPVKYPDKFS QASKDFCEALLEKDPEKRLGFRDETCDKLRAHPLFKDLNWRQLEAGMLMPPFIPDSKTVY AKDIQDVGAFSTVKGVAFDKTDTEFFQEFATGNCPIPWQEEMIETGIFGELNVWRSDGQM PDDMKGISGGSSSSSKSGMCLVS NT seq 1692 nt NT seq  +upstreamnt  +downstreamnt atggatttcgggtctttggagaccgtggtggccaactctgccttcatcgccgcccgaggc agctttgacggcagcagctcccaaccctcccgggacaagaagtacctggccaagctcaag ctgcccccgctgtccaagtgtgagtccctccgcgacagcctcagcctggagtttgagagt gtgtgcttggagcagcccatcggcaagaagctctttcagcagttcctacaatcggcagag aagcacctgccggccctggagctctggaaagacatcgaggactatgacacggcagacaat gacctccagccacagaaggcccagaccatcctggcccagtacctggacccccaggccaaa ctcttctgcagcttcctggatgaggggatagtggcgaagtttaaggaggggcctgtggag atccaggacgggctcttccagcccctgctgcaggccaccctggcacacctgggccaagcc cccttccaggagtacctgggcagcctgtacttcctgaggttcctgcagtggaagtggctg gaagcccagcccatgggggaggactggttcctggacttcagggtcctagggaaagggggc ttcggggaggtgtcggcctgccagatgaaggcgaccggcaagctgtatgcctgcaagaag ctgaacaagaagcggctgaagaagaggaagggctaccagggtgctatggtggagaagaag attctgatgaaagtacacagcaggttcatcgtgtctctggcctatgcgtttgaaaccaaa gccgacctctgtctggtgatgaccatcatgaacggaggtgacatcaggtaccacatctac aacgtgaatgaggagaaccctggcttcccggagccgcgcgccctcttctacacggcgcag atcatctgcggcctggagcacctgcaccagaggcggatcgtctaccgcgacctcaagccc gagaacgtgctgctggacaatgacggcaatgtccggatctctgaccttgggctggccgtg gagctgctggacggacagagcaagaccaagggctacgcagggaccccaggtttcatggcc cccgagctcctgcagggcgaggagtacgacttctccgtggactactttgccctgggggtc accctgtatgagatgattgcggccagaggacccttccgagcccgtggagagaaggtggag aacaaggagctgaagcaccggatcatctcagagcccgtgaagtaccctgataagttcagc caggccagcaaggacttctgcgaggcgctgctggagaaggacccggagaagcgcctgggg ttcagagatgagacctgcgacaagctccgtgcccaccccctcttcaaggaccttaactgg aggcagctggaggctgggatgctgatgccccctttcatcccagactccaaaactgtctac gcaaaggatattcaggacgtgggtgccttttccaccgtcaaaggtgtggcctttgacaaa acagacacagaattctttcaggaatttgccactggcaactgccccatcccctggcaggag gagatgatcgagacgggcatctttggcgagctgaacgtgtggcgctcggacggtcagatg ccggacgacatgaagggcatctccgggggctccagctcctcgtccaagtcagggatgtgt ctggtttcctag

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