Homo sapiens (human): 131890 Help Entry 131890            CDS       T01001                                  Gene name GRK7, GPRK7 Definition (RefSeq) G protein-coupled receptor kinase 7   KO K00909   rhodopsin kinase [EC:2.7.11.14] Organism hsa  Homo sapiens (human) Pathway hsa04062   Chemokine signaling pathway hsa04144   Endocytosis hsa04744   Phototransduction Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     131890 (GRK7)  09150 Organismal Systems   09151 Immune system    04062 Chemokine signaling pathway     131890 (GRK7)   09157 Sensory system    04744 Phototransduction     131890 (GRK7)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     131890 (GRK7) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.14  rhodopsin kinase      131890 (GRK7) Protein kinases [BR:hsa01001]  Serine/threonine kinases: AGC group   GRK family [OT]    131890 (GRK7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr RGS Kinase-like Motif Other DBs NCBI-GeneID:  131890 NCBI-ProteinID:  NP_631948 OMIM:  606987 HGNC:  17031 Ensembl:  ENSG00000114124 Vega:  OTTHUMG00000159068 Pharos:  Q8WTQ7(Tchem) UniProt:  Q8WTQ7 LinkDB All DBs Position 3q23 AA seq 553 aa AA seqDB search MVDMGALDNLIANTAYLQARKPSDCDSKELQRRRRSLALPGLQGCAELRQKLSLNFHSLC EQQPIGRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAPG NPQPFLSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWKL FEMQPVSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEK EILEKVSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQI ACGMLHLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPE ILMEKVSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFT EEAKDICRLFLAKKPEQRLGSREKSDDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYA KDIAEIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELNDPNRPTGCE EGNSSKSGVCLLL NT seq 1662 nt NT seq  +upstreamnt  +downstreamnt atggtggacatgggggccctggacaacctgatcgccaacaccgcctacctgcaggcccgg aagccctcggactgcgacagcaaagagctgcagcggcggcggcgtagcctggccctgccc gggctgcagggctgcgcggagctccgccagaagctgtccctgaacttccacagcctgtgt gagcagcagcccatcggtcgccgcctcttccgtgacttcctagccacagtgcccacgttc cgcaaggcggcaaccttcctagaggacgtgcagaactgggagctggccgaggagggaccc accaaagacagcgcgctgcaggggctggtggccacttgtgcgagtgcccctgccccgggg aacccgcaacccttcctcagccaggccgtggccaccaagtgccaagcagccaccactgag gaagagcgagtggctgcagtgacgctggccaaggctgaggccatggctttcttgcaagag cagccctttaaggatttcgtgaccagcgccttctacgacaagtttctgcagtggaaactc ttcgagatgcaaccagtgtcagacaagtacttcactgagttcagagtgctggggaaaggt ggttttggggaggtatgtgccgtccaggtgaaaaacactgggaagatgtatgcctgtaag aaactggacaagaagcggctgaagaagaaaggtggcgagaagatggctctcttggaaaag gaaatcttggagaaggtcagcagccctttcattgtctctctggcctatgcctttgagagc aagacccatctctgccttgtcatgagcctgatgaatgggggagacctcaagttccacatc tacaacgtgggcacgcgtggcctggacatgagccgggtgatcttttactcggcccagata gcctgtgggatgctgcacctccatgaactcggcatcgtctatcgggacatgaagcctgag aatgtgcttctggatgacctcggcaactgcaggttatctgacctggggctggccgtggag atgaagggtggcaagcccatcacccagagggctggaaccaatggttacatggctcctgag atcctaatggaaaaggtaagttattcctatcctgtggactggtttgccatgggatgcagc atttatgaaatggttgctggacgaacaccattcaaagattacaaggaaaaggtcagtaaa gaggatctgaagcaaagaactctgcaagacgaggtcaaattccagcatgataacttcaca gaggaagcaaaagatatttgcaggctcttcttggctaagaaaccagagcaacgcttagga agcagagaaaagtctgatgatcccaggaaacatcatttctttaaaacgatcaactttcct cgcctggaagctggcctaattgaacccccatttgtgccagacccttcagtggtttatgcc aaagacatcgctgaaattgatgatttctctgaggttcggggggtggaatttgatgacaaa gataagcagttcttcaaaaactttgcgacaggtgctgttcctatagcatggcaggaagaa attatagaaacgggactgtttgaggaactgaatgaccccaacagacctacgggttgtgag gagggtaattcatccaagtctggcgtgtgtttgttattgtaa

Homo sapiens (human): 6011 Help Entry 6011              CDS       T01001                                  Gene name GRK1, GPRK1, RHOK, RK Definition (RefSeq) G protein-coupled receptor kinase 1   KO K00909   rhodopsin kinase [EC:2.7.11.14] Organism hsa  Homo sapiens (human) Pathway hsa04062   Chemokine signaling pathway hsa04144   Endocytosis hsa04744   Phototransduction Disease H00787   Congenital stationary night blindness Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     6011 (GRK1)  09150 Organismal Systems   09151 Immune system    04062 Chemokine signaling pathway     6011 (GRK1)   09157 Sensory system    04744 Phototransduction     6011 (GRK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hsa01001]     6011 (GRK1) Enzymes [BR:hsa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.14  rhodopsin kinase      6011 (GRK1) Protein kinases [BR:hsa01001]  Serine/threonine kinases: AGC group   GRK family [OT]    6011 (GRK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr RGS Pkinase_fungal Kinase-like Motif Other DBs NCBI-GeneID:  6011 NCBI-ProteinID:  NP_002920 OMIM:  180381 HGNC:  10013 Ensembl:  ENSG00000185974 Vega:  OTTHUMG00000185528 Pharos:  Q15835(Tchem) UniProt:  Q15835 LinkDB All DBs Structure PDB:  5AFP Thumbnails Position 13q34 AA seq 563 aa AA seqDB search MDFGSLETVVANSAFIAARGSFDGSSSQPSRDKKYLAKLKLPPLSKCESLRDSLSLEFES VCLEQPIGKKLFQQFLQSAEKHLPALELWKDIEDYDTADNDLQPQKAQTILAQYLDPQAK LFCSFLDEGIVAKFKEGPVEIQDGLFQPLLQATLAHLGQAPFQEYLGSLYFLRFLQWKWL EAQPMGEDWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKK ILMKVHSRFIVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQ IICGLEHLHQRRIVYRDLKPENVLLDNDGNVRISDLGLAVELLDGQSKTKGYAGTPGFMA PELLQGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKHRIISEPVKYPDKFS QASKDFCEALLEKDPEKRLGFRDETCDKLRAHPLFKDLNWRQLEAGMLMPPFIPDSKTVY AKDIQDVGAFSTVKGVAFDKTDTEFFQEFATGNCPIPWQEEMIETGIFGELNVWRSDGQM PDDMKGISGGSSSSSKSGMCLVS NT seq 1692 nt NT seq  +upstreamnt  +downstreamnt atggatttcgggtctttggagaccgtggtggccaactctgccttcatcgccgcccgaggc agctttgacggcagcagctcccaaccctcccgggacaagaagtacctggccaagctcaag ctgcccccgctgtccaagtgtgagtccctccgcgacagcctcagcctggagtttgagagt gtgtgcttggagcagcccatcggcaagaagctctttcagcagttcctacaatcggcagag aagcacctgccggccctggagctctggaaagacatcgaggactatgacacggcagacaat gacctccagccacagaaggcccagaccatcctggcccagtacctggacccccaggccaaa ctcttctgcagcttcctggatgaggggatagtggcgaagtttaaggaggggcctgtggag atccaggacgggctcttccagcccctgctgcaggccaccctggcacacctgggccaagcc cccttccaggagtacctgggcagcctgtacttcctgaggttcctgcagtggaagtggctg gaagcccagcccatgggggaggactggttcctggacttcagggtcctagggaaagggggc ttcggggaggtgtcggcctgccagatgaaggcgaccggcaagctgtatgcctgcaagaag ctgaacaagaagcggctgaagaagaggaagggctaccagggtgctatggtggagaagaag attctgatgaaagtacacagcaggttcatcgtgtctctggcctatgcgtttgaaaccaaa gccgacctctgtctggtgatgaccatcatgaacggaggtgacatcaggtaccacatctac aacgtgaatgaggagaaccctggcttcccggagccgcgcgccctcttctacacggcgcag atcatctgcggcctggagcacctgcaccagaggcggatcgtctaccgcgacctcaagccc gagaacgtgctgctggacaatgacggcaatgtccggatctctgaccttgggctggccgtg gagctgctggacggacagagcaagaccaagggctacgcagggaccccaggtttcatggcc cccgagctcctgcagggcgaggagtacgacttctccgtggactactttgccctgggggtc accctgtatgagatgattgcggccagaggacccttccgagcccgtggagagaaggtggag aacaaggagctgaagcaccggatcatctcagagcccgtgaagtaccctgataagttcagc caggccagcaaggacttctgcgaggcgctgctggagaaggacccggagaagcgcctgggg ttcagagatgagacctgcgacaagctccgtgcccaccccctcttcaaggaccttaactgg aggcagctggaggctgggatgctgatgccccctttcatcccagactccaaaactgtctac gcaaaggatattcaggacgtgggtgccttttccaccgtcaaaggtgtggcctttgacaaa acagacacagaattctttcaggaatttgccactggcaactgccccatcccctggcaggag gagatgatcgagacgggcatctttggcgagctgaacgtgtggcgctcggacggtcagatg ccggacgacatgaagggcatctccgggggctccagctcctcgtccaagtcagggatgtgt ctggtttcctag

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