KEGG   Homo sapiens (human): 137362
Entry
137362            CDS       T01001                                 
Symbol
GOT1L1
Name
(RefSeq) glutamic-oxaloacetic transaminase 1 like 1
  KO
K14454  aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00220  Arginine biosynthesis
hsa00250  Alanine, aspartate and glutamate metabolism
hsa00270  Cysteine and methionine metabolism
hsa00330  Arginine and proline metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00400  Phenylalanine, tyrosine and tryptophan biosynthesis
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01210  2-Oxocarboxylic acid metabolism
hsa01230  Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    137362 (GOT1L1)
   00270 Cysteine and methionine metabolism
    137362 (GOT1L1)
   00220 Arginine biosynthesis
    137362 (GOT1L1)
   00330 Arginine and proline metabolism
    137362 (GOT1L1)
   00350 Tyrosine metabolism
    137362 (GOT1L1)
   00360 Phenylalanine metabolism
    137362 (GOT1L1)
   00400 Phenylalanine, tyrosine and tryptophan biosynthesis
    137362 (GOT1L1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:hsa01007]
    137362 (GOT1L1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    137362 (GOT1L1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    137362 (GOT1L1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.1  aspartate transaminase
     137362 (GOT1L1)
Amino acid related enzymes [BR:hsa01007]
 Aminotransferase (transaminase)
  Class I
   137362 (GOT1L1)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    137362 (GOT1L1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   137362 (GOT1L1)
  Exosomal proteins of other body fluids (saliva and urine)
   137362 (GOT1L1)
SSDB
Motif
Pfam: Aminotran_1_2
Other DBs
NCBI-GeneID: 137362
NCBI-ProteinID: NP_689626
HGNC: 28487
Ensembl: ENSG00000169154
UniProt: Q8NHS2
LinkDB
Position
8:complement(37934281..37940124)
AA seq 421 aa
MPTLSVFMDVPLAHKLEGSLLKTYKQDDYPNKIFLAYRVCMTNEGHPWVSLVVQKTRLQI
SQDPSLNYEYLPTMGLKSFIQASLALLFGKHSQAIVENRVGGVHTVGDSGAFQLGVQFLR
AWHKDARIVYIISSQKELHGLVFQDMGFTVYEYSVWDPKKLCMDPDILLNVVEQIPHGCV
LVMGNIIDCKLTPSGWAKLMSMIKSKQIFPFFDIPCQGLYTSDLEEDTRILQYFVSQGFE
FFCSQSLSKNFGIYDEGVGMLVVVAVNNQQLLCVLSQLEGLAQALWLNPPNTGARVITSI
LCNPALLGEWKQSLKEVVENIMLTKEKVKEKLQLLGTPGSWGHITEQSGTHGYLGLNSQQ
VEYLVRKKHIYIPKNGQINFSCINANNINYITEGINEAVLLTESSEMCLPKEKKTLIGIK
L
NT seq 1266 nt   +upstreamnt  +downstreamnt
atgcccaccctttcagtgttcatggatgtgcccctcgcccacaagctagagggcagcttg
ttaaagacctacaaacaagatgattacccgaacaagatattcttagcctatagagtctgc
atgacaaatgaaggccatccctgggtttctctcgtggtgcagaagactcgactacagatt
tcacaggatccctccctgaattatgagtacttgcccaccatgggcctgaaatcattcatc
caggcctctctagcactcctctttggaaagcacagccaagccattgtggagaacagggta
gggggtgtacacactgttggtgacagtggtgccttccagcttggcgtccagtttctcaga
gcttggcataaggatgctcgtatagtttacatcatctcttctcaaaaagaactgcatgga
ctcgtcttccaggacatgggctttacagtttatgaatactctgtctgggaccccaagaag
ctatgcatggaccccgacatactcctcaatgtggtggagcagatcccacatggctgtgtc
cttgtgatggggaacattatcgactgcaagttgacaccaagtgggtgggcaaagttgatg
tccatgataaagagcaagcagatattcccattttttgatattccctgtcaaggtttatac
accagtgacttggaagaagatactagaatcttacaatactttgtgtctcaaggctttgag
ttcttctgcagccagtctctgtccaagaattttggcatttatgatgaaggagtggggatg
ctagtggtggtggcagtcaacaaccagcagctgctgtgtgtcctctcccagctggaagga
ttagcccaggccctgtggctaaacccccccaacacgggtgcacgtgtcatcacctccatc
ctctgcaaccctgctctgctgggagaatggaagcagagtctaaaagaagttgtagagaac
atcatgctaaccaaggaaaaagtgaaggagaaactccagctcctgggaacccctgggtcc
tggggtcacatcaccgagcagagtgggacccacggctatcttggactcaactcccagcag
gtggaatacctggtcaggaagaagcacatctatatccccaagaacggtcagattaacttc
agctgtatcaatgccaacaacataaattacatcactgagggcatcaatgaggctgtcctc
ctcacagagagctcagagatgtgtcttccaaaggaaaaaaaaacactgattggaataaaa
ctttag

KEGG   Homo sapiens (human): 2805
Entry
2805              CDS       T01001                                 
Symbol
GOT1, AST, AST1, ASTQTL1, GIG18, SGOT, cAspAT, cCAT
Name
(RefSeq) glutamic-oxaloacetic transaminase 1
  KO
K14454  aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00220  Arginine biosynthesis
hsa00250  Alanine, aspartate and glutamate metabolism
hsa00270  Cysteine and methionine metabolism
hsa00330  Arginine and proline metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00400  Phenylalanine, tyrosine and tryptophan biosynthesis
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01210  2-Oxocarboxylic acid metabolism
hsa01230  Biosynthesis of amino acids
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    2805 (GOT1)
   00270 Cysteine and methionine metabolism
    2805 (GOT1)
   00220 Arginine biosynthesis
    2805 (GOT1)
   00330 Arginine and proline metabolism
    2805 (GOT1)
   00350 Tyrosine metabolism
    2805 (GOT1)
   00360 Phenylalanine metabolism
    2805 (GOT1)
   00400 Phenylalanine, tyrosine and tryptophan biosynthesis
    2805 (GOT1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:hsa01007]
    2805 (GOT1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    2805 (GOT1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    2805 (GOT1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.1  aspartate transaminase
     2805 (GOT1)
Amino acid related enzymes [BR:hsa01007]
 Aminotransferase (transaminase)
  Class I
   2805 (GOT1)
Membrane trafficking [BR:hsa04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    2805 (GOT1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   2805 (GOT1)
  Exosomal proteins of other body fluids (saliva and urine)
   2805 (GOT1)
SSDB
Motif
Pfam: Aminotran_1_2
Other DBs
NCBI-GeneID: 2805
NCBI-ProteinID: NP_002070
OMIM: 138180
HGNC: 4432
Ensembl: ENSG00000120053
UniProt: P17174 A0A140VK69
Structure
LinkDB
Position
10:complement(99396870..99430624)
AA seq 413 aa
MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQK
IANDNSLNHEYLPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFL
ARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLEN
APEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWA
IRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPP
AQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGM
FSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTKIQ
NT seq 1242 nt   +upstreamnt  +downstreamnt
atggcacctccgtcagtctttgccgaggttccgcaggcccagcctgtcctggtcttcaag
ctcactgccgacttcagggaggatccggacccccgcaaggtcaacctgggagtgggagca
tatcgcacggatgactgccatccctgggttttgccagtagtgaagaaagtggagcagaag
attgctaatgacaatagcctaaatcacgagtatctgccaatcctgggcctggctgagttc
cggagctgtgcttctcgtcttgcccttggggatgacagcccagcactcaaggagaagcgg
gtaggaggtgtgcaatctttggggggaacaggtgcacttcgaattggagctgatttctta
gcgcgttggtacaatggaacaaacaacaagaacacacctgtctatgtgtcctcaccaacc
tgggagaatcacaatgctgtgttttccgctgctggttttaaagacattcggtcctatcgc
tactgggatgcagagaagagaggattggacctccagggcttcctgaatgatctggagaat
gctcctgagttctccattgttgtcctccacgcctgtgcacacaacccaactgggattgac
ccaactccggagcagtggaagcagattgcttctgtcatgaagcaccggtttctgttcccc
ttctttgactcagcctatcagggcttcgcatctggaaacctggagagagatgcctgggcc
attcgctattttgtgtctgaaggcttcgagttcttctgtgcccagtccttctccaagaac
ttcgggctctacaatgagagagtcgggaatctgactgtggttggaaaagaacctgagagc
atcctgcaagtcctttcccagatggagaagatcgtgcggattacttggtccaatcccccc
gcccagggagcacgaattgtggccagcaccctctctaaccctgagctctttgaggaatgg
acaggtaatgtgaagacaatggctgaccggattctgaccatgagatctgaactcagggca
cgactagaagccctcaaaacccctgggacctggaaccacatcactgatcaaattggcatg
ttcagcttcactgggttgaaccccaagcaggttgagtatctggtcaatgaaaagcacatc
tacctgctgccaagtggtcgaatcaacgtgagtggcttaaccaccaaaaatctagattac
gtggccacctccatccatgaagcagtcaccaaaatccagtga

KEGG   Homo sapiens (human): 2806
Entry
2806              CDS       T01001                                 
Symbol
GOT2, DEE82, KAT4, KATIV, KYAT4, mitAAT
Name
(RefSeq) glutamic-oxaloacetic transaminase 2
  KO
K14455  aspartate aminotransferase, mitochondrial [EC:2.6.1.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00220  Arginine biosynthesis
hsa00250  Alanine, aspartate and glutamate metabolism
hsa00270  Cysteine and methionine metabolism
hsa00330  Arginine and proline metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00400  Phenylalanine, tyrosine and tryptophan biosynthesis
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01210  2-Oxocarboxylic acid metabolism
hsa01230  Biosynthesis of amino acids
hsa04975  Fat digestion and absorption
Disease
H00606  Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    2806 (GOT2)
   00270 Cysteine and methionine metabolism
    2806 (GOT2)
   00220 Arginine biosynthesis
    2806 (GOT2)
   00330 Arginine and proline metabolism
    2806 (GOT2)
   00350 Tyrosine metabolism
    2806 (GOT2)
   00360 Phenylalanine metabolism
    2806 (GOT2)
   00400 Phenylalanine, tyrosine and tryptophan biosynthesis
    2806 (GOT2)
 09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    2806 (GOT2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:hsa01007]
    2806 (GOT2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.1  aspartate transaminase
     2806 (GOT2)
Amino acid related enzymes [BR:hsa01007]
 Aminotransferase (transaminase)
  Class I
   2806 (GOT2)
SSDB
Motif
Pfam: Aminotran_1_2
Other DBs
NCBI-GeneID: 2806
NCBI-ProteinID: NP_002071
OMIM: 138150
HGNC: 4433
Ensembl: ENSG00000125166
UniProt: P00505
Structure
LinkDB
Position
16:complement(58707131..58734316)
AA seq 430 aa
MALLHSGRVLPGIAAAFHPGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKM
NLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENSEV
LKSGRFVTVQTISGTGALRIGASFLQRFFKFSRDVFLPKPTWGNHTPIFRDAGMQLQGYR
YYDPKTCGFDFTGAVEDISKIPEQSVLLLHACAHNPTGVDPRPEQWKEIATVVKKRNLFA
FFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADE
AKRVESQLKILIRPMYSNPPLNGARIAAAILNTPDLRKQWLQEVKVMADRIIGMRTQLVS
NLKKEGSTHNWQHITDQIGMFCFTGLKPEQVERLIKEFSIYMTKDGRISVAGVTSSNVGY
LAHAIHQVTK
NT seq 1293 nt   +upstreamnt  +downstreamnt
atggccctgctgcactccggccgcgtcctccccgggatcgccgccgccttccacccgggc
ctcgccgccgcggcctctgccagagccagctcctggtggacccatgtggaaatgggacct
ccagatcccattctgggagtcactgaagcctttaagagggacaccaatagcaaaaagatg
aatctgggagttggtgcctaccgggatgataatggaaagccttacgttctgcctagcgtc
cgcaaggcagaggcccagattgccgcaaaaaatttggacaaggaatacctgcccattggg
ggactggctgaattttgcaaggcatctgcagaactagccctgggtgagaacagcgaagtc
ttgaagagtggccggtttgtcactgtgcagaccatttctggaactggagccttaaggatc
ggagccagttttctgcaaagattttttaagttcagccgagatgtctttctgcccaaacca
acctggggaaaccacacacccatcttcagggatgctggcatgcagctacaaggttatcgg
tattatgaccccaagacttgcggttttgacttcacaggcgctgtggaggatatttcaaaa
ataccagagcagagtgttcttcttctgcatgcctgcgcccacaatcccacgggagtggac
ccgcgtccggaacagtggaaggaaatagcaacagtggtgaagaaaaggaatctctttgcg
ttctttgacatggcctaccaaggctttgccagtggtgatggtgataaggatgcctgggct
gtgcgccacttcatcgaacagggcattaatgtttgcctctgccaatcatatgccaagaac
atgggcttatatggtgagcgtgtaggagccttcactatggtctgcaaagatgcggatgaa
gccaaaagggtagagtcacagttgaagatcttgatccgtcccatgtattccaaccctccc
ctcaatggggcccggattgctgctgccattctgaacaccccagatttgcgaaaacaatgg
ctgcaagaagtgaaagtcatggctgaccgcatcattggcatgcggactcaactggtctcc
aacctcaagaaggagggttccacccacaattggcaacacatcaccgaccaaattggcatg
ttctgtttcacagggctaaagcctgaacaggtggagcggctgatcaaggagttctccatc
tacatgacaaaagatggccgcatctctgtggcaggggtcacctccagcaacgtgggctac
cttgcccatgccattcaccaggtcaccaagtaa

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