KEGG   Homo sapiens (human): 140735
Entry
140735            CDS       T01001                                 
Symbol
DYNLL2, DNCL1B, Dlc2, RSPH22
Name
(RefSeq) dynein light chain LC8-type 2
  KO
K10418  dynein light chain LC8-type
Organism
hsa  Homo sapiens (human)
Pathway
hsa04814  Motor proteins
hsa04962  Vasopressin-regulated water reabsorption
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
  Element
N01295  Rab7-regulated microtubule minus-end directed transport
N01534  Dynein recruitment to the kinetochore
N01846  Retrograde axonal/dendrite transport, Dynein
N01847  Regulation of dynein-mediated retrograde transport
N01850  MYO5B-mediated vesicle transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    140735 (DYNLL2)
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    140735 (DYNLL2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    140735 (DYNLL2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    140735 (DYNLL2)
   04812 Cytoskeleton proteins [BR:hsa04812]
    140735 (DYNLL2)
Cilium and associated proteins [BR:hsa03037]
 Motile cilia and associated proteins
  Dynein arm
   140735 (DYNLL2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     140735 (DYNLL2)
SSDB
Motif
Pfam: Dynein_light Nop Ectatomin
Other DBs
NCBI-GeneID: 140735
NCBI-ProteinID: NP_542408
OMIM: 608942
HGNC: 24596
Ensembl: ENSG00000264364
Pharos: Q96FJ2(Tdark)
UniProt: Q96FJ2
Structure
LinkDB
Position
17:58083419..58095542
AA seq 89 aa
MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR
NFGSYVTHETKHFIYFYLGQVAILLFKSG
NT seq 270 nt   +upstreamnt  +downstreamnt
atgtctgaccggaaggcagtgatcaagaacgcagacatgtctgaggacatgcaacaggat
gccgttgactgcgccacgcaggccatggagaagtacaatatagagaaggacattgctgcc
tatatcaagaaggaatttgacaagaaatataaccctacctggcattgtatcgtgggccga
aattttggcagctacgtcacacacgagacaaagcacttcatctatttttacttgggtcaa
gttgcaatcctcctcttcaagtcaggctag

KEGG   Homo sapiens (human): 1778
Entry
1778              CDS       T01001                                 
Symbol
DYNC1H1, CDCBM13, CMT2O, DHC1, DHC1a, DNCH1, DNCL, DNECL, DYHC, Dnchc1, HL-3, SMALED1, p22
Name
(RefSeq) dynein cytoplasmic 1 heavy chain 1
  KO
K10413  dynein cytoplasmic 1 heavy chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04814  Motor proteins
hsa04962  Vasopressin-regulated water reabsorption
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
  Element
N01295  Rab7-regulated microtubule minus-end directed transport
N01534  Dynein recruitment to the kinetochore
N01846  Retrograde axonal/dendrite transport, Dynein
N01847  Regulation of dynein-mediated retrograde transport
Disease
H00264  Charcot-Marie-Tooth disease
H00455  Spinal muscular atrophy
H00773  Autosomal dominant intellectual developmental disorder
H01881  Complex cortical dysplasia with other brain malformations
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    1778 (DYNC1H1)
  09142 Cell motility
   04814 Motor proteins
    1778 (DYNC1H1)
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    1778 (DYNC1H1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    1778 (DYNC1H1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    1778 (DYNC1H1)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1778 (DYNC1H1)
   04147 Exosome [BR:hsa04147]
    1778 (DYNC1H1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Motor proteins
     Dynein complex
      1778 (DYNC1H1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     1778 (DYNC1H1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   1778 (DYNC1H1)
SSDB
Motif
Pfam: DHC_N1 AAA_6 DHC_N2 AAA_9 AAA_8 Dynein_C AAA_7 AAA_lid_11 DYN_lid MT AAA_5 Dynein_heavy Dynein_AAA_lid AAA_22 AAA AAA_16 AAA_33 Mg_chelatase AAA_18 nSTAND3 T2SSE AAA_lid_1 AAA_19 AAA_25 SLFN_GTPase-like
Other DBs
NCBI-GeneID: 1778
NCBI-ProteinID: NP_001367
OMIM: 600112
HGNC: 2961
Ensembl: ENSG00000197102
Pharos: Q14204(Tbio)
UniProt: Q14204
Structure
LinkDB
Position
14:101964573..102056443
AA seq 4646 aa
MSEPGGGGGEDGSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGEAPAALEAALEEKS
ALEQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIK
RTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAP
SVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPT
FLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLT
LDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAI
FTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVF
QTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVI
VRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSK
EGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGA
IREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTA
YMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTI
ESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAIS
LIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETV
FNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWV
NKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPKIKNVVH
ELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYR
NALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQ
ALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMT
EFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQ
RFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTD
WEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQ
VALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQY
ASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQ
KNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEH
INSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHL
LPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLE
RERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSRE
GEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYIT
WIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQ
PPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQ
MANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALG
HQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQE
ALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLA
MTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSA
GNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSL
LSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGL
MMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLF
THVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVR
IMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKG
KEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFS
MLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRR
ITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEAL
LYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCE
YRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTW
VKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIP
SLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEG
LIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKD
YIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSG
AGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVL
DSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIR
NLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNY
IVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFI
NHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKL
KKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIK
KQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEIS
DAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLE
DDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLK
SLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQAN
IQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFI
MNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRV
LITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAE
RPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEV
TRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVL
YENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPT
YDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIW
LDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSI
MEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQA
DKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLR
AGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLG
WSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEF
DQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSW
LGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTL
HTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEG
KKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGG
AKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGV
TGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIF
TVDFEIATKEDPRSFYERGVAVLCTE
NT seq 13941 nt   +upstreamnt  +downstreamnt
atgtcggagcccgggggcggcggcggcgaggacggctcggccggattggaagtgtcggcc
gtgcagaatgtggcggacgtgtcggtgctgcagaagcacctgcgcaagctggtgccgctg
ctgctggaggacggcggcgaggcgccggccgcgctggaggcggcgctggaggagaagagc
gccctggagcagatgcgcaagttcctttcggacccgcaggtccacacggtgctggtggag
cgctccacgctcaaagaggacgtcggtgatgaaggagaagaagaaaaagaattcatttcc
tataacatcaacatagacattcattatggggttaaatccaatagcttggcattcattaaa
cgtactcccgtgattgatgcagataaacccgtgtcttctcagctccgggtccttacactc
agtgaagactcgccctacgaaactttgcattctttcattagcaatgcagtggctcctttt
tttaagtcctacattagagagtctggcaaggcagacagggatggtgataaaatggctcct
tcagttgaaaagaagattgcagaactcgaaatgggactccttcacttgcagcaaaatatt
gaaattccggagatcagcctgccgattcatccaatgatcacaaatgttgcaaaacagtgt
tatgagcgtggagaaaagccaaaagttacagactttggtgataaggttgaagacccaaca
tttcttaatcagttacaatctggagttaaccgctggatccgagaaattcaaaaagtgacc
aaactggatcgagatcctgcatcaggaactgccttacaggaaattagtttttggctaaac
ttggaacgtgcgttataccgcatccaggagaaacgggagagcccggaagttctcctgact
ctggatatcttgaaacatggcaagcgcttccatgccaccgtcagttttgacactgacaca
ggtctaaaacaggctttggaaactgtgaatgactacaatcctctgatgaaagatttccct
ctgaatgatttgctgtctgccacggagctggacaaaataagacaggcgcttgttgccatt
ttcacacatttgagaaagatccgaaacacaaaatatcctattcagagggcactgcgtttg
gtggaggcaatttcaagagacttgagttctcaattactcaaagtattgggcactaggaaa
ttgatgcatgttgcttatgaagaatttgaaaaagttatggtagcatgctttgaagttttt
cagacttgggatgatgagtatgagaaacttcaggtattgttgagagacatcgtcaaaaga
aaaagggaagaaaatctgaagatggtgtggcgtatcaaccctgcccacaggaagctgcag
gcccgccttgaccagatgagaaaatttagacgccagcatgaacagctaagagctgttatc
gtcagggtcctgaggccacaggtcacggcagttgcacaacagaatcaaggagaggtccct
gaaccccaagatatgaaagtggctgaggttctctttgatgctgcagatgcaaatgccatt
gaggaagtaaaccttgcttatgagaacgtcaaggaagtggatggactggatgtttccaaa
gagggcacggaagcctgggaggctgctatgaagaggtacgatgagaggatcgacagagtg
gagacccggatcaccgctcgccttcgggatcagcttggcacagccaagaatgccaacgag
atgtttaggattttctccaggtttaatgcactgtttgtcaggcctcacatccgtggggcc
attcgcgaataccagacccagctgatccagcgcgtgaaagatgacattgagtctcttcac
gacaagttcaaggtccagtacccacagagtcaggcttgtaagatgagtcacgttcgtgac
ttgccccctgtgtcagggtctatcatctgggctaaacagatcgacaggcagctgacggcc
tacatgaagcgggtggaagatgtccttggcaagggctgggagaatcacgtggaggggcag
aagctgaagcaggatggagacagcttccgcatgaagctcaacacgcaggagatctttgat
gactgggcaaggaaggtgcagcagcgcaacctcggtgtctcggggcgcattttcaccatc
gaaagtactcgggttcggggccgaactggaaatgtgcttaagctgaaagttaactttctt
cctgagattatcacactatccaaagaagtccggaacctcaaatggcttggtttccgcgtc
ccactggcgattgtgaacaaagcccatcaagcaaaccagctttacccgtttgccatctca
ctgatcgagagcgttcgtacctatgaacggacctgcgagaaggtggaggagcggaacacc
atttcccttttggtggctggcttgaaaaaggaagtgcaggccctgatcgcagaaggcatt
gcgttggtgtgggagtcctacaaacttgacccatatgtacagcgcttagcagagactgtc
ttcaacttccaagaaaaggtggatgatctgctgatcattgaagaaaaaatagacctagaa
gtccgttccttggaaacttgtatgtatgaccataagacattctcggaaatcttgaacaga
gtccagaaagcagtggatgacttaaatctgcactcctattccaatttgcccatctgggtc
aacaagcttgacatggagattgaaagaatattgggcgtccgtctgcaagctggcctgaga
gcttggacgcaggttcttcttggacaagctgaagataaagcagaagttgacatggacaca
gatgctccacaagttagtcacaagcctggtggagagccaaagatcaaaaatgtcgttcat
gagctaagaataaccaatcaggtaatctacttgaatccaccaattgaagagtgcagatac
aagctgtatcaggaaatgtttgcctggaagatggttgtactgtctctccccaggatccag
agtcagaggtaccaggtgggtgtacattacgaattgactgaggaagagaaattctatcgg
aatgctttaacacggatgcctgatggccctgttgccctggaagagtcgtattctgctgtc
atgggcattgtatctgaagttgaacagtatgtcaaggtttggcttcagtatcagtgttta
tgggatatgcaagctgaaaacatctataacagacttggagaagatctcaacaaatggcag
gctctcctggtccaaataaggaaggccagaggaacctttgacaatgcagaaaccaagaaa
gagtttggaccagtagttatagattatggcaaggtacaatctaaggtgaacttgaaatat
gactcttggcataaggaggttcttagcaaatttgggcagatgctaggatcaaacatgacg
gaattccattcccagatctcaaagtcccgccaagagttggagcagcactcagtagacacg
gccagcacctccgatgcagtgaccttcatcacctatgtgcagtctttgaaacggaagatc
aagcagtttgagaagcaagttgagctctaccgcaatggccagcgcttactggaaaagcaa
aggttccagttcccaccttcctggctttatattgacaacatcgagggagagtggggagcc
ttcaatgacatcatgcggcgaaaggactctgccattcagcagcaggtggcaaacctgcaa
atgaagattgtccaggaggatcgggccgtggaaagccgcaccaccgacctgctgactgac
tgggagaagaccaagcctgtcacgggcaaccttcgcccagaagaggcacttcaggctctc
accatatatgaggggaagtttggtaggctgaaggacgacagagagaagtgtgcaaaggcc
aaggaggcgctggaattgacagatactgggcttctcagtggcagtgaagagcgcgtgcag
gtggccttagaagaattacaggacctcaaaggcgtttggtcagaactttctaaggtttgg
gagcaaatcgatcagatgaaggagcaaccctgggtttcagtacagcctcgaaagcttcga
caaaatttggatgccctcctgaaccagctgaaaagcttccctgcccggttgcgacagtat
gcgtcctatgagtttgttcagaggcttctgaaaggttacatgaagataaatatgctggtg
attgaactgaaatccgaagcacttaaagaccgccattggaaacagctcatgaaaaggctt
cacgttaattgggttgtttctgagctaacccttggccaaatctgggatgttgacttgcag
aaaaatgaagcgattgtcaaggatgtactgcttgtggcacaaggggagatggctttggaa
gaatttttgaagcagataagagaagtgtggaatacttatgaactagacttggttaattat
cagaacaagtgccgcttgatccgtggctgggatgacctcttcaacaaggtcaaagaacac
atcaacagcgtctcggccatgaagctctctccgtattacaaggtttttgaagaggatgct
ctcagctgggaagataagctgaacaggatcatggctctctttgatgtgtggattgatgtg
cagaggcggtgggtctacctggaaggtatcttcacaggcagtgcagatatcaagcacctg
ctgccagtggaaacccagcggtttcagagcatcagcactgagtttttggctctaatgaaa
aaagtgtccaagtctccccttgttatggatgttctgaacatccagggagtacagaggtct
ctggaaagattggcagacctgctaggaaagatccagaaagcattgggagaatatctggaa
agagagcggtcatctttccccaggttctattttgtgggtgatgaagatttgcttgaaatc
attggaaacagcaagaatgtcgctaaattacagaaacacttcaagaagatgtttgctgga
gtttcgagcatcatcctgaacgaggataactctgttgttttgggtatttcatctcgggaa
ggagaggaggttatgtttaaaactcctgtgtcaattactgaacatcccaaaatcaatgag
tggctcacattggtagaaaaggagatgagagtcaccctggccaaactgcttgctgagtct
gttacggaagttgagatttttggtaaagcaacttcaattgacccaaatacctacatcact
tggattgataaataccaggcccagcttgtggttttgtcagcccagatagcctggtctgag
aacgtggagaccgcactgagcagcatgggcggaggtggagatgccgcgcccttgcactct
gtgctgagcaatgtggaggtcaccctcaatgtgttagcagactctgtcctcatggagcag
cccccactccgaaggcggaagctagaacacttgattacagagttggttcaccagagagat
gttacaaggtccttgatcaaaagcaagattgacaacgccaaatcttttgaatggctcagc
cagatgcgattttactttgaccctaagcaaactgatgtgttacagcagttgtcaattcaa
atggcaaatgccaaatttaactatggctttgagtacctgggtgttcaggacaaactggtc
cagacccccctcactgaccgctgctatttgacaatgacacaagccttggaggccaggctg
gggggttccccatttggacctgctggaactgggaaaacagagtctgtcaaagctcttggc
catcagcttggacggtttgttttagttttcaactgtgatgaaacctttgatttccaggca
atgggccggatctttgtgggcctttgccaggtgggtgcctggggctgctttgacgagttc
aaccgcctggaggagcggatgctctcggctgtgtcccagcaggtgcagtgcatacaggaa
gcactgcgtgaacattccaaccccaactacgacaagacctctgcccccattacttgtgag
ctgctgaacaaacaagtcaaggtgagcccggacatggccatcttcatcaccatgaaccct
ggctacgcgggccggtctaaccttcctgacaacttgaagaagctgttccggagcttggcc
atgaccaagcccgaccggcagttaatcgcccaggtcatgctgtactcacagggtttccgc
actgctgaagtgcttgccaacaaaatcgtcccgttttttaaactatgcgatgagcagctc
tcttcccaaagccattatgacttcggtcttcgggctttgaagagtgtgctggtgagtgca
ggcaatgtgaagagagagagaatccagaagataaagagggagaaagaggaacgaggggaa
gcagttgatgaaggagaaattgctgaaaatctccctgaacaagagattctgatacagagc
gtctgtgagacgatggtgccaaagctggtggcagaggacatcccgctgctcttcagcctc
ctgtcggacgtgttccctggagtccagtatcacaggggtgagatgactgcccttcgagag
gagctgaagaaagtgtgtcaggagatgtatttgacatatggagatggagaagaagttggt
ggaatgtgggttgaaaaggttctccagctctatcagatcacccagatcaatcatggcctg
atgatggtggggccctcgggaagtgggaagagcatggcctggcgtgtcctgctgaaggca
ttggagagactcgagggtgtggaaggtgtggcccatatcatcgaccccaaggccatcagc
aaagaccacctctacggaaccctggaccccaacaccagggaatggacagatgggctcttc
acacacgtgctgagaaagatcatcgacagcgtgagaggcgagctgcagaagcgccagtgg
atcgtcttcgatggcgatgtggatccagagtgggttgagaacttgaactcagtgctggat
gacaataagctcctaactttgcccaatggagagcgcctcagtcttccacccaatgtgaga
ataatgtttgaggtacaggacttgaaatacgcgaccttggccacagtgtcgcgctgcggc
atggtctggttcagtgaggatgtgctgagcaccgacatgatcttcaacaacttcctggcc
aggctgcgcagcatcccgctggatgaaggggaggatgaggcacagcggcggcgtaagggc
aaagaggatgagggggaggaggccgcttcccccatgctgcagatccaaagagatgcagct
acgatcatgcaaccgtacttcacgtccaacggcctggtcaccaaggcgctagagcacgcc
ttccagctggagcacatcatggacctaacacgcctgcgctgcctgggctcgctcttctcc
atgctgcaccaggcctgccgcaacgtggcgcagtataacgccaaccatcccgacttcccc
atgcagatcgagcagctggagcgctacattcagcgatatctggtttatgccatactctgg
tccctgtctggagacagccggctaaaaatgagagcagagctgggtgaatacatcagaaga
atcacgaccgtgcctctgcccactgcgcccaacatacccattatcgattatgaggtgtcc
atcagcggagaatggtctccgtggcaggccaaggtgcctcagattgaagtggagacgcac
aaggtggcagcccctgatgtcgtcgtgccaacgctggacacagtccgccacgaagccctc
ttgtacacttggctggccgaacacaagcccctggtcttgtgtggccctcctgggtctggc
aagaccatgacactcttcagcgccctccgggccttgcctgacatggaggtggtgggtctc
aacttctccagtgctactactccagagctgcttctgaagacttttgatcactactgcgag
tacaggcgcacacctaatggggtggttttggctcctgttcaacttggaaagtggctggtg
ttgttctgtgatgaaatcaacttgccagatatggataaatatgggacccagagggtcata
tccttcatcagacagatggtggagcacggaggcttttaccgtacctcagatcaaacatgg
gtgaagctggagagaatccagtttgttggggcttgtaatccccccacagaccctggaaga
aagcccctctcacacaggttcctgcgccacgtgcctgtcgtgtatgtggattacccgggc
cccgcctccctcacacagatctacggcaccttcaaccgcgccatgctgaggctcattcca
tccctgcggacgtatgcagagccgctcactgctgccatggtggagttctacaccatgtct
caggagagattcacccaggatacacaacctcactatatctattcaccccgtgaaatgact
aggtgggtgagaggcatctttgaagcgctgagacctctggagaccctgcctgttgaaggc
ctcattcggatttgggcacatgaagctctgcgtctcttccaagatagactcgtagaggat
gaggagaggcgttggactgatgagaacatcgacacggttgctctgaagcacttccctaac
atcgacagagagaaggcaatgagccgacccatcttgtacagcaactggctgtcaaaggat
tacatcccagtagaccaagaagagttaagagattatgtcaaagctaggctgaaggtcttt
tatgaagaagaacttgatgttccgctggtgctgtttaatgaagtcctagaccacgtgctg
aggattgacagaatattccgtcaacctcaaggccacttgcttctgattggtgttagtgga
gcaggaaaaactaccctgtctcgtttcgtcgcctggatgaacggtttgagtgtgtaccag
attaaggtccataggaagtacacaggggaagactttgatgaagatctacggacagtgttg
agacgttctggctgtaaaaatgaaaagatagcatttataatggatgaatctaatgtgtta
gattctggattcctggagcgaatgaatacccttctggccaatggagaggtgcctggtctc
tttgaaggagacgagtatgccaccttgatgacgcagtgcaaagagggggcacagaaggaa
ggcctgatgctggactcgcacgaggagctctacaagtggttcactagccaggttatccgc
aacctccacgtcgtgttcaccatgaacccgtcctcggagggactcaaggaccgggcagct
acatcaccagcacttttcaacaggtgtgtgttgaattggtttggagactggtccaccgaa
gcactgtatcaggttggcaaagaattcacaagtaagatggatctggagaagccaaattac
atcgtgcctgattacatgccagttgtgtatgataagctgccgcagccaccatcccatcgg
gaagccattgtgaacagctgtgtgtttgttcatcagactcttcaccaggcgaatgctcgg
ctagcaaagcgaggcggcagaacgatggccatcacccctcgccactacctggacttcatc
aatcactatgccaacctgttccacgagaagcggagcgagctggaggagcagcagatgcac
ttgaacgtggggctcaggaagatcaaagagacagtcgaccaggtagaagaactgcgtcgt
gacttgaggataaagagccaagagctggaggtgaagaatgcagcagccaatgacaagctg
aaaaagatggtgaaagaccagcaggaggctgaaaagaagaaggttatgagccaagaaatc
caggaacagctgcataagcagcaggaggtaattgcagacaaacagatgagtgtcaaagaa
gatcttgataaggtggaacctgccgtcattgaggcccagaatgctgtgaagtcgatcaag
aagcagcacctggtggaggtgaggtccatggccaaccctcctgctgctgtgaagctggcg
ctggagtccatctgcctgctgctgggggaaagcaccacagactggaagcagatccgctcc
atcatcatgcgggagaacttcatccccaccatcgtcaacttctctgcagaggagatcagt
gacgccataagggagaagatgaagaaaaattacatgtccaatccaagttacaattatgaa
attgtgaatcgggcttccctggcttgcggccctatggtgaaatgggcaattgcacagctt
aactatgcagacatgttaaagagagtggagcccctacgcaatgagctgcagaagctggaa
gatgacgccaaggacaaccagcagaaggccaacgaggtggagcagatgatccgagacctg
gaagccagcatcgcccgctacaaggaggaatacgccgtcctgatctcagaggcccaggcc
atcaaggcagacctggcagctgtcgaggcaaaagtaaaccggagcactgctcttctgaag
agcttgtctgctgaacgtgaacgatgggaaaaaacaagtgaaactttcaaaaaccagatg
tccaccattgctggggactgtctcttgtcagctgcgttcattgcctacgcgggttacttt
gaccagcagatgcgtcagaacttgttcactacctggtcccatcacctacagcaagccaac
atccagttccgtacagatattgccaggacggaatacctttccaatgctgatgagcgtctt
cgctggcaggccagctccttgcctgctgatgacctttgcacagaaaatgccatcatgctg
aaacgattcaataggtatccgctgatcattgacccctctggacaggccacagaattcatt
atgaatgaatataaggatcgtaagatcacacggaccagcttcctggatgacgccttcaga
aagaacttagagagtgcactgagattcggtaacccccttctggtccaggatgtggaaagc
tacgatccagttttgaacccggtgctgaaccgtgaagtgcggcgaacaggggggagagtg
ctgatcactctcggggaccaggacatagacctgtcgccatcgtttgtcatcttcctgtcc
acccgggatccaactgtcgagttcccaccagatctctgttcccgggttacttttgtaaac
ttcacagttacccgtagcagtttacaaagccagtgtctaaatgaagtacttaaagcagaa
agacctgatgtggacgagaaacgatctgatcttcttaaacttcaaggggaatttcagctc
cgtttgcgtcagctggaaaaatctctactacaagctctgaacgaggtgaaagggcgcatt
ttggatgacgacacgatcataaccactctggagaacctgaagagagaggctgcagaggtc
accaggaaagttgaggagacggacattgtcatgcaggaggtggagaccgtgtcccagcag
tacctcccgctctccaccgcctgcagcagcatctacttcaccatggagtccctcaagcag
atacacttcttgtaccagtactccctccagtttttcctggacatttatcacaacgtccta
tacgagaacccgaacctgaagggtgtcaccgaccacacacagcgcctgtccattataaca
aaggacctcttccaggtggcgtttaaccgagtggctcgaggcatgctgcatcaggaccac
attacctttgccatgctgctggcaagaatcaaactgaagggcaccgtgggggagcccacc
tacgatgcagaattccagcacttcttgagaggaaatgagattgtcctgagtgctggctcc
acccccaggatccagggcctgactgtggagcaggcggaggcggtggtgaggctgagctgc
cttcccgcgtttaaggacttgattgcaaaggttcaggcagacgagcaatttggcatctgg
ctggacagcagctccccggagcagactgtgccctacctctggagtgaagaaacacctgca
acacccattggccaggccatccaccgcctgctcctgatccaggctttccggcccgatcgc
ctgttggccatggcccacatgtttgtttcaacaaaccttggggagtctttcatgtccatc
atggagcagccgctcgacctgacccacattgtgggcacagaggtgaagcccaacactcct
gtcttaatgtgctctgtgcctggttatgatgccagtggacatgtcgaggaccttgcagcc
gagcagaacacgcagatcacttcaattgcaatcggctctgcagaaggctttaaccaagca
gataaggcaataaacaccgctgtaaagtcgggcaggtgggtgatgctgaagaatgtgcat
ctggccccagggtggctgatgcagctggagaagaagttgcattccctgcagccgcatgcc
tgcttccgactcttcctcaccatggagatcaaccccaaggtgcctgtgaatctgctccgt
gcgggccgcatctttgtgttcgagccaccgccaggggtgaaggccaacatgctgaggacg
ttcagcagcattcccgtctcacggatatgcaagtctcccaacgagcgtgcccgcttgtac
ttcctgctggcctggtttcatgcgatcatccaagaacgcttacgatacgcaccactgggg
tggtcaaagaagtatgaatttggagagtctgacctgcggtcagcttgcgatacggtggac
acgtggctggatgacacggccaagggcaggcagaacatctcaccggataagatcccgtgg
tctgcactaaagaccttaatggcccagtccatttatggcgggcgcgtggacaacgagttt
gaccagcgtctgctcaacaccttcctggagcgcctgttcacaaccaggagtttcgacagt
gagtttaagctggcatgcaaggtcgacggacataaagacattcaaatgccagatggcatc
aggcgagaggagtttgtgcagtgggtggagttgctccccgacacccagacgccctcctgg
ctgggcctgcccaacaacgccgagagagtcctccttaccacacagggtgtggacatgatc
agtaaaatgctgaagatgcagatgttggaggatgaggacgacctggcctacgcagagact
gagaagaagacgaggacagactccacgtccgacgggcgccctgcctggatgcggacactg
cacaccaccgcgtccaactggctgcacctcatcccccagacgctgagccacctcaagcgc
accgtggagaatatcaaggatcctttgttcaggttctttgagagagaagtgaagatgggc
gcaaagctgcttcaggacgttcgccaggaccttgcagatgtcgtccaggtgtgcgaagga
aagaagaagcagaccaactacttgcgcacgctgatcaacgagctagtgaaagggatcttg
cctcggagctggtcccactacacggtgcctgccggcatgaccgtcatccagtgggtgtcc
gacttcagcgagaggatcaaacagctgcagaacatctcactggcagctgcatctggtggc
gccaaggagctaaagaacatccacgtgtgcctgggtggcctgttcgtgcctgaggcgtac
atcactgccaccaggcagtatgtggcccaggccaacagctggtccctggaggagctctgc
ctggaagtcaacgtcaccacctcacagggcgccacccttgacgcttgcagcttcggagtc
acgggtttgaaacttcaaggggccacgtgcaacaacaacaagctgtcactgtccaatgcc
atctcaaccgcccttcccctgacgcagctgcgctgggtcaagcagacaaacaccgagaag
aaggccagtgtggtaaccttacctgtctacctgaacttcacccgtgcagacctcatcttc
accgtggacttcgaaattgctacaaaggaggatcctcgcagcttctacgagcggggtgtc
gcagtcttgtgcacagagtaa

KEGG   Homo sapiens (human): 1780
Entry
1780              CDS       T01001                                 
Symbol
DYNC1I1, DNCI1, DNCIC1
Name
(RefSeq) dynein cytoplasmic 1 intermediate chain 1
  KO
K10415  dynein cytoplasmic 1 intermediate chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04814  Motor proteins
hsa04962  Vasopressin-regulated water reabsorption
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
  Element
N01295  Rab7-regulated microtubule minus-end directed transport
N01534  Dynein recruitment to the kinetochore
N01846  Retrograde axonal/dendrite transport, Dynein
N01847  Regulation of dynein-mediated retrograde transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    1780 (DYNC1I1)
  09142 Cell motility
   04814 Motor proteins
    1780 (DYNC1I1)
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    1780 (DYNC1I1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    1780 (DYNC1I1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    1780 (DYNC1I1)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1780 (DYNC1I1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Motor proteins
     Dynein complex
      1780 (DYNC1I1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     1780 (DYNC1I1)
SSDB
Motif
Pfam: WD40 Dynein_IC2
Other DBs
NCBI-GeneID: 1780
NCBI-ProteinID: NP_004402
OMIM: 603772
HGNC: 2963
Ensembl: ENSG00000158560
Pharos: O14576(Tbio)
UniProt: O14576 A4D1I7 Q8N542
LinkDB
Position
7:95772554..96110322
AA seq 645 aa
MSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETE
ALLQSIGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPL
TRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSE
EDEEDEEMVESKVGQDSELENQDKKQEVKEAPPRELTEEEKQQILHSEEFLIFFDRTIRV
IERALAEDSDIFFDYSGRELEEKDGDVQAGANLSFNRQFYDEHWSKHRVVTCMDWSLQYP
ELMVASYNNNEDAPHEPDGVALVWNMKFKKTTPEYVFHCQSSVMSVCFARFHPNLVVGGT
YSGQIVLWDNRSHRRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLITVSTDGKMCSWSL
DMLSTPQESMELVYNKSKPVAVTGMAFPTGDVNNFVVGSEEGTVYTACRHGSKAGIGEVF
EGHQGPVTGINCHMAVGPIDFSHLFVTSSFDWTVKLWTTKHNKPLYSFEDNADYVYDVMW
SPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEGASALNRVRWAQAGKEVAVGDSEG
RIWVYDVGELAVPHNDEWTRFARTLVEIRANRADSEEEGTVELSA
NT seq 1938 nt   +upstreamnt  +downstreamnt
atgtctgacaaaagtgacttaaaagctgagctagagcgcaaaaagcagcgcttagcacag
ataagagaagagaagaaacggaaggaagaggagaggaaaaagaaagaggctgatatgcag
cagaagaaagaacccgttcaggacgactctgatctggatcgcaaacgacgagagacagag
gctttgctgcaaagcattggtatctcaccggagccgcctctagtgcagccgctgcatttt
ttaacatgggatacctgttattttcattatttagtcccaacccctatgtctccctcctcg
aaatcagtgagcactcccagtgaagctggaagccaagactcaggcgatctggggccatta
acaaggaccctgcagtgggacacagacccctcagtgctccagctgcagtcagactcagaa
cttggaagaagactgcataaactgggcgtgtcaaaggtcacccaagtggatttcctgcca
agggaagtagtgtcctactcaaaggagacccagactcctcttgccacgcatcagtctgaa
gaggatgaggaagatgaggaaatggtggaatctaaagttggccaggactcagaactggaa
aatcaggacaaaaaacaggaagtgaaggaagcccctccaagagagttgacagaggaagaa
aaacagcagatccttcattcagaggaatttctcatcttttttgaccggacaatacgggta
attgaaagagccctggctgaagattccgacatcttttttgactacagcggccgagagtta
gaggaaaaagatggggatgttcaggctggagccaatctttctttcaatcgtcagttctat
gatgaacattggtccaagcatcgagtggtcacttgtatggactggtccctccagtaccct
gagctgatggtggcttcttacaacaacaatgaagatgctccccatgaaccagatggagtg
gccttggtttggaacatgaagtttaagaaaaccacaccagaatacgtcttccactgtcag
tcctctgtgatgtcggtctgcttcgcccgtttccatcctaacttggtggttggtgggact
tactcgggccagattgtcctctgggacaatcgcagtcatcgaaggactccagtgcagcgg
acacccttatcagctgctgcacacacgcatcccgtgtactgtgtaaatgttgttgggacc
cagaatgctcataacctcatcactgtctccactgatggcaaaatgtgttcctggagcctg
gacatgctctcaactccacaggagagcatggagctggtgtacaataagtccaagcctgtc
gctgttaccggaatggctttcccaacgggagacgtcaataacttcgtggttggcagtgag
gaaggtacagtctacacggcttgtcgtcatggaagcaaagcaggtattggtgaggtcttt
gaaggtcaccaagggccagtgacaggaattaactgccacatggcagtgggcccaatcgac
ttttctcacctgtttgtcacatcatcatttgactggactgtcaaactgtggaccaccaag
cacaacaagccgctctactcctttgaagacaatgcagactatgtgtacgatgtcatgtgg
tcccccgtgcatcctgcgctttttgcctgcgtggacgggatggggcgcttggacctctgg
aacctcaacaatgacaccgaggttccaacagcaagtgtggccattgagggggcatccgcc
ctaaaccgtgttcgttgggcccaagctggcaaagaagttgctgttggggactcggaaggc
cgtatttgggtctatgacgttggagagcttgcagttccccacaatgatgaatggacccga
tttgccaggacccttgtggaaattcgtgctaacagagctgatagcgaggaggaaggcact
gttgagttatctgcctag

KEGG   Homo sapiens (human): 1781
Entry
1781              CDS       T01001                                 
Symbol
DYNC1I2, DIC74, DNCI2, IC2, NEDMIBA
Name
(RefSeq) dynein cytoplasmic 1 intermediate chain 2
  KO
K10415  dynein cytoplasmic 1 intermediate chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04814  Motor proteins
hsa04962  Vasopressin-regulated water reabsorption
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
  Element
N01295  Rab7-regulated microtubule minus-end directed transport
N01534  Dynein recruitment to the kinetochore
N01846  Retrograde axonal/dendrite transport, Dynein
N01847  Regulation of dynein-mediated retrograde transport
Disease
H02461  Neurodevelopmental disorder with microcephaly
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    1781 (DYNC1I2)
  09142 Cell motility
   04814 Motor proteins
    1781 (DYNC1I2)
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    1781 (DYNC1I2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    1781 (DYNC1I2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    1781 (DYNC1I2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1781 (DYNC1I2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Motor proteins
     Dynein complex
      1781 (DYNC1I2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     1781 (DYNC1I2)
SSDB
Motif
Pfam: Dynein_IC2 WD40 ANAPC4_WD40 Rrn6_K-rich
Other DBs
NCBI-GeneID: 1781
NCBI-ProteinID: NP_001258714
OMIM: 603331
HGNC: 2964
Ensembl: ENSG00000077380
Pharos: Q13409(Tbio)
UniProt: Q13409 A0A140VKE9
Structure
LinkDB
Position
2:171687469..171750158
AA seq 638 aa
MSDKSELKAELERKKQRLAQIREEKKRKEEERKKKETDQKKEAVAPVQEESDLEKKRREA
EALLQSMGLTPESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDP
SVLQLHSDSDLGRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVA
PKPPIEPEEEKTLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQ
INIFFDYSGRDLEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYN
NNEDAPHEPDGVALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLW
DNRSNKRTPVQRTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQD
SMELVHKQSKAVAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPIT
GIHCHAAVGAVDFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALF
ACVDGMGRLDLWNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVG
EQIAVPRNDEWARFGRTLAEINANRADAEEEAATRIPA
NT seq 1917 nt   +upstreamnt  +downstreamnt
atgtcagacaaaagtgaattaaaggctgagttggaacgtaagaagcagcgactggcccaa
atcagagaggaaaagaagagaaaagaagaagaaaggaaaaaaaaagaaacagaccagaag
aaggaagctgttgctcctgtgcaagaagaatcagatcttgaaaaaaaaaggagagaagct
gaagcattgcttcaaagcatggggctaactccagaatcccccattgttttttctgaatac
tgggtccctcctcctatgtctccatcctccaaatctgtgagcactccaagtgaagctgga
agccaagactctggagatggcgccgtgggatctaggacgctgcattgggatacagatcca
tcagttcttcagcttcactcagattccgatttgggacgaggacctattaaacttggaatg
gctaaaatcacgcaagtcgactttcctcctcgagaaattgtcacgtatacaaaggaaact
cagactccagttatggctcaacccaaagaagatgaagaggaagatgatgatgtagtggct
cctaaaccacctattgaacctgaagaagagaaaactttaaagaaagatgaggaaaatgat
agtaaagctccccctcatgagctgactgaagaagaaaagcaacaaatcttgcactctgag
gaatttttaagtttctttgaccattctacaagaattgtagaaagagctctttctgagcag
attaacatcttctttgactatagtgggagagatttggaagacaaagaaggagagattcaa
gcaggtgctaaactgtcattaaatcgacaattttttgacgaacgttggtcaaagcatcgg
gtggttagttgtttggattggtcatctcagtatccggagttactcgtggcttcctataac
aacaatgaagatgcccctcatgagcctgatggtgtggcccttgtatggaatatgaaatac
aaaaaaactaccccagagtatgtgtttcactgccagtcagctgtgatgtctgccacattt
gcaaaatttcatccaaatcttgttgttggtggtacatattcaggccaaattgtgctttgg
gataaccgtagcaataaaagaactccagtgcaaagaactccactgtcagcagctgcacac
acacaccctgtatattgtgtaaatgttgttggaacacaaaatgctcacaatctgattagc
atctctactgatggaaaaatttgttcatggagtctggacatgctttcccatccacaggat
agcatggagttggttcataaacagtcaaaagcagtagctgtgacatctatgtccttccct
gttggagatgtcaacaactttgttgttgggagtgaagaaggttctgtgtacacagcatgc
cgccatggcagcaaagctggaatcagtgagatgtttgaggggcatcaaggaccaatcact
ggcatccattgtcatgcagctgttggagcagtagacttctcacatctttttgtcacttca
tcgtttgactggacagtaaagctttggacaactaagaataacaagcctttgtattcattt
gaagataatgcagactatgtttatgatgttatgtggtcacctacccacccagccctgttt
gcctgtgtggatggcatggggagattggatttgtggaatctcaataatgacacagaggta
ccaactgccagcatttctgtggagggtaatcctgctcttaatcgtgtgagatggacccat
tctggcagagagattgctgtgggtgattctgaaggacagattgttatatacgatgtggga
gagcagattgctgttccccgcaatgatgaatgggcacggtttggccgaacacttgcagaa
attaatgcaaaccgagctgatgcagaggaggaagcagctacccgaatacctgcttag

KEGG   Homo sapiens (human): 1783
Entry
1783              CDS       T01001                                 
Symbol
DYNC1LI2, DNCLI2, LIC2
Name
(RefSeq) dynein cytoplasmic 1 light intermediate chain 2
  KO
K10416  dynein cytoplasmic 1 light intermediate chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04814  Motor proteins
hsa04962  Vasopressin-regulated water reabsorption
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
  Element
N01295  Rab7-regulated microtubule minus-end directed transport
N01534  Dynein recruitment to the kinetochore
N01846  Retrograde axonal/dendrite transport, Dynein
N01847  Regulation of dynein-mediated retrograde transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    1783 (DYNC1LI2)
  09142 Cell motility
   04814 Motor proteins
    1783 (DYNC1LI2)
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    1783 (DYNC1LI2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    1783 (DYNC1LI2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    1783 (DYNC1LI2)
   03036 Chromosome and associated proteins [BR:hsa03036]
    1783 (DYNC1LI2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    1783 (DYNC1LI2)
Membrane trafficking [BR:hsa04131]
 Protein recycling
  Rab GTPases and associated proteins
   Rab4 associated proteins
    1783 (DYNC1LI2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Motor proteins
     Dynein complex
      1783 (DYNC1LI2)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     1783 (DYNC1LI2)
SSDB
Motif
Pfam: DLIC ABC_tran Arf AAA_16 AAA_7 AAA_22 PduV-EutP AAA_29 NACHT ATPase nSTAND3 Roc AAA_24 AAA_25 SRP54
Other DBs
NCBI-GeneID: 1783
NCBI-ProteinID: NP_006132
OMIM: 611406
HGNC: 2966
Ensembl: ENSG00000135720
Pharos: O43237(Tbio)
UniProt: O43237 Q63HJ8
Structure
LinkDB
Position
16:complement(66720893..66751609)
AA seq 492 aa
MAPVGVEKKLLLGPNGPAVAAAGDLTSEEEEGQSLWSSILSEVSTRARSKLPSGKNILVF
GEDGSGKTTLMTKLQGAEHGKKGRGLEYLYLSVHDEDRDDHTRCNVWILDGDLYHKGLLK
FAVSAESLPETLVIFVADMSRPWTVMESLQKWASVLREHIDKMKIPPEKMRELERKFVKD
FQDYMEPEEGCQGSPQRRGPLTSGSDEENVALPLGDNVLTHNLGIPVLVVCTKCDAVSVL
EKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTTPA
LVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQ
VFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPASVPSSSPGTSVKKPDPNIK
NNAASEGVLASFFNSLLSKKTGSPGSPGAGGVQSTAKKSGQKTVLSNVQEELDRMTRKPD
SMVTNSSTENEA
NT seq 1479 nt   +upstreamnt  +downstreamnt
atggcgccggtgggggtggagaagaagctgctgctaggtcccaacgggcccgcggtggcg
gccgccggcgacctgaccagtgaggaggaggaaggccagagcctatggtcctccattctg
agcgaagtgtccacccgcgccaggtccaagctgccgtccggcaagaacatcctggtcttc
ggtgaagatggttctggtaaaacaaccctcatgactaaactacaaggagctgagcatggc
aaaaaaggaagaggcctagaatatctctacctcagtgtccatgatgaggaccgagatgat
cacacgcgctgcaacgtgtggattctggatggagacttgtaccacaaaggcctgctgaaa
tttgcagtttctgctgaatccttgccagagaccctcgtcatttttgttgcagacatgtct
agaccttggactgtgatggaatctctgcagaaatgggctagtgttttacgtgagcacatt
gataaaatgaaaattccaccagaaaaaatgagggagctggaacggaagtttgtgaaagat
tttcaagactatatggaacctgaagaaggttgtcaaggttccccacagagaagaggccct
ctgacctcaggctccgatgaagaaaatgttgccctgcctctgggtgacaatgtgctgact
cataacctggggatcccggtgttggtggtgtgcacaaagtgtgatgcggtgagtgtcctg
gagaaggagcacgattacagggatgagcatttggactttatccagtcacacctgcggagg
ttctgccttcagtatggagctgccttgatttacacatcagtgaaagaagagaaaaacctc
gacttgttgtataagtatattgttcataaaacatacggtttccacttcaccacacctgcc
ttagttgtggaaaaggatgccgtttttatacctgcaggctgggacaatgaaaagaaaata
gctattttacatgaaaattttacaaccgtgaagccggaagatgcatatgaagactttatt
gtgaaacctcccgtgagaaagctggtccacgacaaagagttggcagcagaagatgagcag
gtgttcctaatgaagcaacagtcactccttgccaagcaaccagccactcccacgagagct
tctgaatctcctgcaagaggaccctctggctctccaaggacccagggtcggggagggcca
gccagtgtgcctagctcctccccaggcacgtcagtaaaaaagccggacccaaacatcaaa
aataatgcagcaagtgaaggggtgttggccagcttcttcaacagtctgttgagtaaaaag
acaggctctcctggaagtcctggtgctggtggggtgcagagcacagccaagaagtcagga
caaaagactgtgttgtcaaatgttcaggaagaactggatagaatgactcgaaagccagac
tctatggtaacaaactcttcaacagaaaatgaagcctga

KEGG   Homo sapiens (human): 51143
Entry
51143             CDS       T01001                                 
Symbol
DYNC1LI1, DLC-A, DLIC-1, DNCLI1, LIC1
Name
(RefSeq) dynein cytoplasmic 1 light intermediate chain 1
  KO
K10416  dynein cytoplasmic 1 light intermediate chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04814  Motor proteins
hsa04962  Vasopressin-regulated water reabsorption
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
  Element
N01295  Rab7-regulated microtubule minus-end directed transport
N01534  Dynein recruitment to the kinetochore
N01846  Retrograde axonal/dendrite transport, Dynein
N01847  Regulation of dynein-mediated retrograde transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    51143 (DYNC1LI1)
  09142 Cell motility
   04814 Motor proteins
    51143 (DYNC1LI1)
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    51143 (DYNC1LI1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    51143 (DYNC1LI1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    51143 (DYNC1LI1)
   03036 Chromosome and associated proteins [BR:hsa03036]
    51143 (DYNC1LI1)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    51143 (DYNC1LI1)
Membrane trafficking [BR:hsa04131]
 Protein recycling
  Rab GTPases and associated proteins
   Rab4 associated proteins
    51143 (DYNC1LI1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Motor proteins
     Dynein complex
      51143 (DYNC1LI1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     51143 (DYNC1LI1)
SSDB
Motif
Pfam: DLIC ABC_tran Roc RsgA_GTPase PduV-EutP AAA_16 DUF815 TsaE AAA_7
Other DBs
NCBI-GeneID: 51143
NCBI-ProteinID: NP_057225
OMIM: 615890
HGNC: 18745
Ensembl: ENSG00000144635
Pharos: Q9Y6G9(Tbio)
UniProt: Q9Y6G9
Structure
LinkDB
Position
3:complement(32525974..32570858)
AA seq 523 aa
MAAVGRVGSFGSSPPGLSSTYTGGPLGNEIASGNGGAAAGDDEDGQNLWSCILSEVSTRS
RSKLPAGKNVLLLGEDGAGKTSLIRKIQGIEEYKKGRGLEYLYLNVHDEDRDDQTRCNVW
ILDGDLYHKGLLKFSLDAVSLKDTLVMLVVDMSKPWTALDSLQKWASVVREHVDKLKIPP
EEMKQMEQKLIRDFQEYVEPGEDFPASPQRRNTASQEDKDDSVVLPLGADTLTHNLGIPV
LVVCTKCDAISVLEKEHDYRDEHFDFIQSHIRKFCLQYGAALIYTSVKENKNIDLVYKYI
VQKLYGFPYKIPAVVVEKDAVFIPAGWDNDKKIGILHENFQTLKAEDNFEDIITKPPVRK
FVHEKEIMAEDDQVFLMKLQSLLAKQPPTAAGRPVDASPRVPGGSPRTPNRSVSSNVASV
SPIPAGSKKIDPNMKAGATSEGVLANFFNSLLSKKTGSPGGPGVSGGSPAGGAGGGSSGL
PPSTKKSGQKPVLDVHAELDRITRKPVTVSPTTPTSPTEGEAS
NT seq 1572 nt   +upstreamnt  +downstreamnt
atggcggccgtggggcgagtcggctccttcggttcttctccgccgggattatcctcgact
tacactggcggccccttgggcaacgagatagcgtcgggcaacggtggcgccgcggcaggc
gacgacgaggacgggcagaacctttggtcctgcatcctcagcgaggtctccacccgctcg
cgctccaagctccctgcggggaagaacgtgctactgctgggtgaagatggagctggaaaa
acaagcttaataagaaaaattcagggaatagaggagtataagaaaggaagaggattggaa
tatttgtacttaaatgtgcatgatgaagacagggatgatcaaacaagatgtaatgtttgg
atcttagatggagacctatatcacaaaggcctccttaaattttcactggatgccgtatct
ctgaaggatactctagttatgctggttgttgacatgtcaaagccttggactgctttggat
tctttacagaaatgggcaagtgttgttagagaacatgttgacaaactgaaaatccctcct
gaagaaatgaaacaaatggaacaaaagttgattagagacttccaagaatatgtagagcca
ggagaagacttcccggcttctccccagagaagaaatactgcgtcacaagaagacaaagat
gacagtgtagttttacctctgggtgcggatacacttacacataacttgggcattccagta
ctagtagtttgcacaaagtgtgatgccattagtgtattggagaaagaacatgactacaga
gatgaacattttgattttattcagtcacatatccggaagttttgtttacagtatggtgca
gcacttatttacacttcagtaaaagaaaacaaaaatatagacttagtatataaatacatc
gttcagaaactatatggatttccctataagattcctgctgttgttgtggaaaaggatgca
gtatttattccagcagggtgggataatgataagaaaataggaatattacatgaaaatttt
caaacattaaaagcagaagataattttgaagacatcataactaaaccacctgttcgaaag
tttgtacatgagaaggaaattatggcagaagatgatcaggtgtttcttatgaagctacag
tcccttttagcaaagcaaccaccaactgcagctggaaggcctgtggatgcctcaccaaga
gtcccaggaggctccccacgaacaccaaatagatctgtatcatctaatgttgccagcgtg
tcacccattcctgctgggtcaaaaaaaattgatccaaacatgaaagctggagctacaagt
gaaggcgttctggcaaatttcttcaacagtttgttgagtaaaaagactggctctccagga
ggccctggtgtgagtggtggtagccctgcaggtggggctggaggtggaagcagtggttta
ccaccatccaccaaaaagtcaggccagaagcctgtcttagatgttcatgcagaactagac
agaattacacgaaaaccagttacagtttctcccacaacacctacatctcctacggaagga
gaagcttcttga

KEGG   Homo sapiens (human): 51626
Entry
51626             CDS       T01001                                 
Symbol
DYNC2LI1, CGI-60, D2LIC, LIC3
Name
(RefSeq) dynein cytoplasmic 2 light intermediate chain 1
  KO
K10417  dynein cytoplasmic 2 light intermediate chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04814  Motor proteins
hsa04962  Vasopressin-regulated water reabsorption
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06515  Regulation of kinetochore-microtubule interactions
  Element
N01295  Rab7-regulated microtubule minus-end directed transport
N01534  Dynein recruitment to the kinetochore
Disease
H02157  Short-rib thoracic dysplasia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    51626 (DYNC2LI1)
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    51626 (DYNC2LI1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    51626 (DYNC2LI1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    51626 (DYNC2LI1)
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    51626 (DYNC2LI1)
   04812 Cytoskeleton proteins [BR:hsa04812]
    51626 (DYNC2LI1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Motor proteins
     Dynein complex
      51626 (DYNC2LI1)
Cilium and associated proteins [BR:hsa03037]
 Primary cilia and associated proteins
  Dynein and associated proteins
   51626 (DYNC2LI1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     51626 (DYNC2LI1)
SSDB
Motif
Pfam: DLIC Roc
Other DBs
NCBI-GeneID: 51626
NCBI-ProteinID: NP_057092
OMIM: 617083
HGNC: 24595
Ensembl: ENSG00000138036
Pharos: Q8TCX1(Tdark)
UniProt: Q8TCX1
Structure
LinkDB
Position
2:43774039..43828347
AA seq 351 aa
MPSETLWEIAKAEVEKRGINGSEGDGAEIAEKFVFFIGSKNGGKTTIILRCLDRDEPPKP
TLALEYTYGRRAKGHNTPKDIAHFWELGGGTSLLDLISIPITGDTLRTFSLVLVLDLSKP
NDLWPTMENLLQATKSHVDKVIMKLGKTNAKAVSEMRQKIWNNMPKDHPDHELIDPFPVP
LVIIGSKYDVFQDFESEKRKVICKTLRFVAHYYGASLMFTSKSEALLLKIRGVINQLAFG
IDKSKSICVDQNKPLFITAGLDSFGQIGSPPVPENDIGKLHAHSPMELWKKVYEKLFPPK
SINTLKDIKDPARDPQYAENEVDEMRIQKDLELEQYKRSSSKSWKQIELDS
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgcccagtgaaactctctgggaaattgcaaaagctgaagtggaaaaaaggggaattaat
ggaagtgaaggtgatggagctgaaattgcagaaaaatttgttttcttcattggcagtaaa
aatgggggaaagactactattattctaaggtgtcttgacagagatgaaccaccaaaacca
accttagctttggaatatacatatggaagaagagcaaaagggcacaacacaccaaaagat
atcgctcacttttgggaactcggtggaggaacctctttattggacttaatcagcataccc
atcacaggtgacaccttacggacgttttctcttgttctcgttctggatctttcaaaacct
aatgatctctggcccaccatggaaaatctcttgcaagccacaaaaagccatgtagacaaa
gtgataatgaaactgggaaagacaaatgctaaagcagtttctgaaatgagacagaagatc
tggaataatatgccgaaggatcatcctgatcatgaattaattgacccatttccggtacct
ctggtcataattggaagtaaatatgatgtttttcaggattttgagtctgagaagagaaag
gtaatatgcaagacacttcgatttgttgcacattattatggagcatcattaatgtttacc
agtaaatcagaagctctattactaaaaatacgtggagttatcaaccagttggcatttggc
attgacaaaagcaaatcaatatgtgtggatcagaataaaccgctgtttatcacagcagga
ttggattctttcggtcaaataggatctcctcctgttcctgaaaatgacattggaaagctt
catgcccactcacctatggagttgtggaaaaaagtgtatgaaaagctctttccaccaaag
agtattaacacgctgaaagatatcaaggaccctgcgagagatcctcagtatgctgaaaat
gaagtcgatgagatgagaattcagaaggatctggaactggaacagtacaaaagaagttct
tccaagtcttggaaacaaatcgagcttgattcttga

KEGG   Homo sapiens (human): 79659
Entry
79659             CDS       T01001                                 
Symbol
DYNC2H1, ATD3, DHC1b, DHC2, DNCH2, DYH1B, SRPS2B, SRTD3, hdhc11
Name
(RefSeq) dynein cytoplasmic 2 heavy chain 1
  KO
K10414  dynein cytoplasmic 2 heavy chain
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa04814  Motor proteins
hsa04962  Vasopressin-regulated water reabsorption
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
  Element
N01295  Rab7-regulated microtubule minus-end directed transport
N01534  Dynein recruitment to the kinetochore
N01846  Retrograde axonal/dendrite transport, Dynein
N01847  Regulation of dynein-mediated retrograde transport
Disease
H00511  Short rib-polydactyly syndrome
H00751  Asphyxiating thoracic dystrophy
H02157  Short-rib thoracic dysplasia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    79659 (DYNC2H1)
  09142 Cell motility
   04814 Motor proteins
    79659 (DYNC2H1)
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    79659 (DYNC2H1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    79659 (DYNC2H1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    79659 (DYNC2H1)
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    79659 (DYNC2H1)
   04812 Cytoskeleton proteins [BR:hsa04812]
    79659 (DYNC2H1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Motor proteins
     Dynein complex
      79659 (DYNC2H1)
Cilium and associated proteins [BR:hsa03037]
 Primary cilia and associated proteins
  Dynein and associated proteins
   79659 (DYNC2H1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     79659 (DYNC2H1)
SSDB
Motif
Pfam: AAA_6 DHC_N2 AAA_9 AAA_8 Dynein_C DYNC2H1_AAA_dom AAA_5 AAA_lid_11 DHC_N1 Dynein_heavy DYN_lid AAA_7 MT AAA_22 AAA_16 RsgA_GTPase ABC_tran AAA nSTAND3 AAA_30 nSTAND1 AAA_28 AAA_24 RNA_helicase ATPase_2 AAA_29 AAA_18
Other DBs
NCBI-GeneID: 79659
NCBI-ProteinID: NP_001368
OMIM: 603297
HGNC: 2962
Ensembl: ENSG00000187240
Pharos: Q8NCM8(Tbio)
UniProt: Q8NCM8
Structure
LinkDB
Position
11:103109426..103479863
AA seq 4307 aa
MANGTADVRKLFIFTTTQNYFGLMSELWDQPLLCNCLEINNFLDDGNQMLLRVQRSDAGI
SFSNTIEFGDTKDKVLVFFKLRPEVITDENLHDNILVSSMLESPISSLYQAVRQVFAPML
LKDQEWSRNFDPKLQNLLSELEAGLGIVLRRSDTNLTKLKFKEDDTRGILTPSDEFQFWI
EQAHRGNKQISKERANYFKELFETIAREFYNLDSLSLLEVVDLVETTQDVVDDVWRQTEH
DHYPESRMLHLLDIIGGSFGRFVQKKLGTLNLWEDPYYLVKESLKAGISICEQWVIVCNH
LTGQVWQRYVPHPWKNEKYFPETLDKLGKRLEEVLAIRTIHEKFLYFLPASEEKIICLTR
VFEPFTGLNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDSPQQLLQA
FLKYKELVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLS
EVVNSIVWVRQLELKVDDTIKIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSR
DIQSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVIPAKI
QQVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIKNSKAGSGGK
SQITWDNPKELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNIDLLRQQQRWKD
GLQELRTGLATVEAQGFQASDMHAWKQHWNHQLYKALEHQYQMGLEALNENLPEINIDLT
YKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGEAGDESIFSIMIDRNASGFLTIF
SKAEDLFRRLSAVLHQHKEWIVIGQVDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLP
SAVKVDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLTIMP
QSVEEIGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFEL
MMESHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSA
KLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLASSISKDIESCAQIWAFYEEFQQG
FQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYV
RGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTI
REALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKG
FEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNRVDEDFRSIMT
DIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEI
LGQSTNPSVIQSHLKKLFAGINSVCFDEKSKHITAMKSLEGEVVPFKNKVPLSNNVETWL
NDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAEQIKFTEDVENAIKDHSL
HQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHT
TEDWAWKKQLRFYMKSDHTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMK
MGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCF
DEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGG
RQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQ
HYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQALRLNTMSKFTFTDCTRFDA
LIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGP
SGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQ
VVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLS
CASPATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYRNNLENWIGDYFEKALQWVLKQN
DYVVETSLVGTVMNGLSHLHGCRDHDEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESP
PDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLS
SDTKQPFILVGPEGCGKGMLLRYAFSQLRSTQIATVHCSAQTTSRHLLQKLSQTCMVIST
NTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENI
QIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIW
GSSSKIYLLAGSMVQVYEQVRAKFTVDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPL
DYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARH
NSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRI
DRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQL
AGIEAQQVVLLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGF
FGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIP
EMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAYGATPSRYMTFLHVYS
AISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMIT
VSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESL
SEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIR
ESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNL
KKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLD
REHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGLEKFDL
RRFLCTESEQLIWKSEGLPSDDLSIENALVILQSRVCPFLIDPSSQATEWLKTHLKDSRL
EVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKII
DYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKT
KLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYK
LQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENT
EQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDM
LRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFEDAALWRTYYNNSMCEQE
FPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEI
EPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLK
NLHLVVSWLPVLEKELNTLQPKDTFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNL
MRTYESWTPEQISKKDNTHRAHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGY
NIIDRLFDGAKDVQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRN
KKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQLRI
LGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQGSPILSFIILEQ
FNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGPEDPLQY
LRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKF
VASWKGRLQEAKLQIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLPCFMGWIPQDACGP
YSPDECISLPVYTSAERDRVVTNIDVPCGGNQDQWIQCGAALFLKNQ
NT seq 12924 nt   +upstreamnt  +downstreamnt
atggcgaacgggactgcggacgttcggaagctcttcatcttcactactacccagaattac
ttcgggttgatgtctgaactctgggatcagccactgttgtgcaactgtcttgaaatcaac
aacttcttggatgacggcaaccagatgctcctcagggtgcagcgatccgacgcaggaatc
tccttttccaacacgattgagtttggtgacacaaaagataaagtgctggtgtttttcaag
ctgcgacctgaagtaattactgatgagaatctacatgataacattcttgtttcatctatg
ttagagtcacctattagttctctttaccaagcagtacggcaagtattcgcaccaatgttg
ttaaaggatcaggaatggagcagaaactttgatcccaaacttcagaatcttttgagtgaa
ctagaagctgggttgggtatagttctacgaagatcagacactaacttaacaaaattgaaa
tttaaggaagatgacacacgaggtatccttacaccaagcgatgagttccagttttggata
gaacaagctcaccgtggaaataaacagattagtaaagaaagagccaattattttaaagaa
ttatttgaaacaattgcaagagagttttataacttggacagtctatccttactagaagtt
gttgacttggtggagactactcaggatgttgtagatgatgtgtggagacaaacagaacat
gatcattatcctgagtcacgaatgttgcatctcttagacatcataggtggttcatttgga
aggtttgttcagaaaaagttgggaactttgaacctgtgggaagatccttattatcttgtg
aaagaaagtctgaaagctggtatttcaatttgtgaacagtgggtgatagtctgtaatcat
ctaacaggtcaggtgtggcagcgctatgttcctcatccatggaaaaatgaaaaatatttt
ccagaaacacttgacaaacttggcaaacgccttgaagaggtcttggctattagaacaatt
catgagaagtttctctattttctacctgccagtgaagagaaaatcatatgcctcactcga
gtatttgaaccttttactggcctgaatcctgtgcaatataatccatatactgagcccttg
tggaaagctgcggtgtctcaatatgaaaagattattgcacctgcggaacaaaaaatagca
ggaaaattgaaaaattatatttcagaaattcaagacagtccacagcagcttcttcaagca
ttcctgaaatataaagagttggtaaagcgtccaactataagcaaagaattgatgttagaa
agagaaactttactggcaagacttgtggactcaattaaagattttcgattagactttgag
aatcggtgccgaggaattcctggtgatgcatctggaccactttctggcaaaaatctttca
gaagttgtcaacagtatagtttgggttcgccagttggaattgaaggtagatgatactatc
aagattgcagaggctcttttatctgacttgccaggatttcgatgtttccatcaaagtgcc
aaagatctcttagaccagcttaaactatatgaacaggaacaatttgatgattggtccagg
gatattcaatcaggtttatctgattccagatctggtttgtgtattgaggctagtagtcga
attatggaattggattctaatgatggattactaaaagtgcattattcagatcgtttggtg
attcttctgagagaagttcgtcagctctctgcacttggctttgttattcctgccaaaata
cagcaagttgcaaacattgcacagaaattctgcaagcaagcaattattcttaaacaagtg
gcacatttttataattctattgatcaacaaatgattcaaagtcagaggccaatgatgtta
caatctgccttagcatttgaacagataattaagaattcaaaagcaggaagtggagggaaa
tcacagataacttgggataatcctaaagaattagaaggctatatccaaaaactccaaaat
gctgctgaacggcttgccactgaaaatagaaaactgagaaaatggcacactacattttgt
gaaaaggtggttgttcttatgaatattgatctgcttcggcagcaacagcgctggaaagat
ggattacaagaattgagaactggcttagcaactgtagaagcacagggattccaagcaagt
gacatgcatgcatggaaacaacactggaatcatcaactgtacaaagctctggagcatcag
taccagatgggcttagaagcacttaatgagaatttgccagaaataaatatagacttaact
tacaaacagggacgattacaattcaggcccccttttgaagaaatccgggctaaatattat
agagaaatgaagagattcatcggcattccaaatcagtttaagggagtgggtgaggcagga
gatgaatctattttttctattatgattgatagaaatgcaagtggatttttgacgattttc
agcaaagcagaagatctgtttagaagattgtcagctgttttacaccaacataaggaatgg
attgtaattgggcaagttgatatggaagctctggtggaaaagcatctttttactgtacat
gattgggagaaaaattttaaagcattaaaaataaaggggaaagaagtagaacgacttcca
agtgctgtcaaggtagattgtttaaatattaattgcaaccctgtgaagactgtgattgat
gatctcatccagaagttatttgatctgcttgttctttctttgaagaagtccatacaggct
catttacatgaaattgatacatttgttactgaggctatggaagtcttaacaattatgccc
cagtctgtggaagaaattggtgatgcaaatctacaatatagtaagttacaagaacggaag
ccagagattttgcccttatttcaagaagctgaagacaaaaacagacttttacgaactgtg
gctggtggaggtttagaaacaattagtaatttgaaagccaagtgggataaatttgagtta
atgatggaaagtcaccaacttatgattaaagaccagattgaagtgatgaaaggaaatgtg
aaatcacgtcttcagatctattatcaagaactggaaaaatttaaagctcgttgggaccaa
ctaaagcctggtgatgatgttattgaaactggccaacataatactcttgataaaagtgca
aagttaataaaagagaaaaaaattgagtttgatgatcttgaagtcacaagaaaaaagctg
gttgatgattgccatcattttagactggaagagcctaatttctccctggcaagtagtatc
tctaaagatatcgagagctgtgcccaaatttgggccttttatgaagagtttcaacaagga
tttcaggaaatggccaatgaagactggatcacttttcggactaagacatacctgtttgag
gaatttttgatgaactggcatgacagattaaggaaggttgaagaacattcagtgatgaca
gtgaaattacaatcagaggttgacaaatataaaatcgtaattcctatcttgaaatatgtg
agaggggagcatctttctccagatcactggcttgacctttttcgtctccttggacttcct
agggggactagtctagagaaactactgtttggtgatttgctcagagtagctgatacaatt
gtagccaaagctgccgaccttaaagatttaaatagtcgggcacaaggtgaagttacaatc
agagaagctttacgtgaacttgatctttggggagttggagcagtgtttacattaattgat
tatgaagacagccaaagtcgaactatgaagctgattaaagactggaaagatatagtaaat
caggttggagataatagatgccttctccaatccttaaaggattctccttattataaagga
tttgaagataaagtatcaatttgggaaagaaaacttgcagagttagatgaatacctgcag
aatttaaatcatattcagagaaagtgggtgtatttggaacccattttcggccgtggagca
ttgccaaaagaacagacacgcttcaacagagttgatgaagattttagatcaataatgact
gatatcaagaaagacaatagagtcacaacattaactactcatgctggaataagaaattct
ctactaacaatacttgatcagcttcaaagatgtcagaaatcattaaatgaatttttggag
gaaaaacgctcagcattcccaagattttattttattggtgatgatgacttattagaaata
ttgggccagtctaccaacccatcagtgattcagtctcacctgaagaagctttttgctggt
attaacagtgtttgctttgatgagaaatcaaaacatataactgcaatgaaatctttagag
ggagaagttgtaccttttaaaaataaagttcctctatcaaataatgtagagacatggttg
aatgatttggccttagaaatgaagaaaactttggaacagttgttgaaggaatgtgttact
actgggcgaagttctcaaggtgcagttgacccatctctgttcccttcacagattttatgc
ttggcggagcagattaaattcactgaagatgtagaaaatgctattaaagatcatagtctt
catcagattgaaacacaactggtgaataagttagagcaatatactaacattgatacaagt
tctgaggatccagggaatactgaatcgggcatcctggagcttaaacttaaagccctaatt
cttgacattatccataatattgatgtggtaaagcagttaaaccaaattcaggttcataca
actgaagactgggcttggaaaaaacaacttagattctatatgaaaagtgatcatacatgt
tgtgttcaaatggtggattctgaatttcagtatacttatgaatatcagggtaatgcttcc
aaactggtttatactccactgacagacaagtgctacttaactctcactcaagccatgaag
atgggacttggaggaaatccttatggaccagctggaactgggaaaacggaatcagtaaag
gctttaggtggacttcttggaagacaagttttagtctttaattgtgatgagggcatcgat
gtgaagtcaatgggacgaatatttgttggtttggtgaagtgtggggcctggggttgtttt
gatgaatttaataggctggaagaatctgtactgtcagcagtttctatgcaaatccagaca
attcaagatgctttgaagaatcatagaactgtatgtgaactgcttggcaaggaggtagaa
gtaaattctaattctggaatttttatcactatgaatcctgctggaaaaggttatggagga
agacaaaaactgcctgataatcttaaacagcttttcaggcccgtagctatgtctcatcca
gacaatgagcttattgcagaagttattctctattcggaaggctttaaagacgctaaagta
ttgagcagaaaattggtagctattttcaatctatctagggaacttttgacacctcagcaa
cattatgattggggtttgagagctttgaagacagttctgagaggaagtggaaatctcctt
agacagctaaacaaaagtggcactacacagaatgctaatgaaagtcatattgtggtacaa
gcactgaggcttaataccatgtcaaagtttacgtttactgattgcacccggtttgatgca
ctgataaaagatgtctttccgggaattgaattgaaagaagtggaatatgatgaactaagt
gctgcattaaagcaggtctttgaagaggccaattatgaaattatacccaatcagatcaaa
aaggctttagaattgtatgaacagttatgccagaggatgggagttgttattgttggtcca
agtggtgctggaaaatcaacgctttggagaatgttaagggctgcgctttgtaaaactggc
aaagtagtgaaacaatatactatgaatcccaaagctatgcctcgatatcaattattaggc
catattgacatggacacaagagaatggtctgatggtgttttgacaaatagtgctcgtcaa
gtggttcgggaacctcaagatgtcagctcatggataatctgtgatggtgatattgaccct
gaatggatagaatctctgaattctgttctggatgataatcgactgctgactatgcccagt
ggagaaaggattcagtttggcccaaatgttaactttgtatttgaaactcatgatttaagt
tgtgcatcaccagccacaatatctagaatgggaatgatctttcttagtgatgaagagaca
gatcttaattctctgataaaatcttggttgaggaatcagcctgctgaatatagaaataat
cttgaaaattggattggagattattttgaaaaggctttacaatgggttctaaagcagaat
gactatgtggtagaaacaagtttggttgggactgtgatgaatggtttgtcacatctacat
ggttgcagagatcatgacgaattcattattaatctcataaggggacttggtggaaatctg
aatatgaagtcacgtttggaatttaccaaagaggtttttcattgggcacgagaatctcct
ccagactttcacaaacctatggatacctactatgactctactaggggtcgattagcaaca
tatgtgcttaagaagccagaagacttgactgctgatgatttcagtaacggcttaactctt
ccagtcattcagactcctgacatgcaacgaggtctagattatttcaaaccatggttaagt
tctgatactaaacagccctttattctggtaggaccagaaggatgtggcaaagggatgctg
ctcaggtacgcattttcacaactccggtccactcaaattgctacagttcactgtagtgca
caaaccacttctcgacatctcctgcagaaactgagccagacttgcatggtaatcagtact
aatactggtcgtgtatacagaccaaaagactgtgaaagacttgttctgtacttaaaagat
atcaacctacctaaacttgataaatgggggaccagtactttggtagcattcctacaacag
gtattgacgtatcaaggattttatgatgaaaatttggaatgggttggtctagaaaatatt
caaattgtggcttctatgtcagctggaggaagactgggaagacataaacttactaccaga
tttacttccatcgttcgtctttgttctatagattacccagaaagagagcagttacaaacg
atttatggagcatatttggaaccagttctacataaaaatctgaagaatcattctatttgg
ggttcttcatcaaaaatttatcttttagcaggatctatggtacaagtgtatgaacaggtg
cgagccaaatttacagttgatgattatagtcactatttctttactccttgcattcttacc
caatgggttcttggcttatttagatatgatttagaaggaggatcctcaaaccatccacta
gattatgtgttagaaattgtagcatatgaggcacggcgcttatttcgtgacaaaattgtt
ggtgcaaaggaacttcatttatttgacatcattttaacatcagtgtttcaaggagattgg
ggctcagacatattagacaatatgtcagatagtttctacgttacatggggagctcggcat
aattcaggagcaagggcagccccaggacaaccattacctccacatggaaaaccacttgga
aaactaaactctactgatctcaaggatgttattaaaaagggtcttattcattatggacga
gataaccagaatttagacattttacttttccacgaagtcttggagtatatgtctaggata
gatagagtgctgagtttccctggaggttcacttctattagcaggacgcagtggtgtaggt
cgtcggaccatcacttctttagtcagtcacatgcatggagcggtcctgttttctccaaag
atttccagaggatatgaactgaagcagttcaaaaatgatctcaaacatgtgctgcaactt
gcaggaattgaagcacaacaggtagttttacttcttgaggattaccagtttgtacatcct
acatttttggagatgatcaatagccttttgtcttcaggtgaagttcctggactctatact
cttgaagaattagagcccttgctgttaccacttaaggatcaagcttcacaagatggtttt
tttggaccagtcttcaattacttcacatatagaattcagcaaaacttgcatattgtcttg
ataatggattctgcaaattcaaacttcatgataaactgtgagagtaatccagctttgcat
aagaaatgccaggtgttgtggatggagggttggtccaatagcagtatgaagaaaatacct
gaaatgttattcagtgaaacaggtggtggagaaaaatacaatgataaaaaacgaaaagaa
gaaaagaaaaaaaattcagttgatcctgattttctaaaatcatttttattaatccatgaa
tcttgtaaagcatatggtgctacaccaagccgatacatgacctttttacatgtgtattct
gccattagtagtagcaagaaaaaggaattattaaaaagacaaagtcatttgcaggctggt
gtatctaaactaaatgaagctaaagctcttgtggatgaactgaacagaaaagctggagaa
caaagtgtgttacttaaaacgaagcaagatgaagcagatgctgcccttcaaatgatcaca
gtgtcaatgcaggatgctagtgagcaaaaaacagaacttgaaagactgaagcacagaata
gcagaagaagttgttaaaattgaagaaagaaaaaataaaattgatgatgaattaaaagaa
gtacaacctttagtcaatgaagctaaactagcagttggaaacattaagcccgaatcactt
tcagaaattcgctcactacgcatgccacctgatgtaattagagatattcttgaaggagtt
ttaaggttgatgggtatctttgatacatcttgggtgagcatgaaaagtttccttgcaaaa
agaggtgtaagagaagacatagcaacctttgatgcccgaaatatttcaaaggaaataaga
gagagtgttgaagaacttctttttaaaaataaaggctcttttgatccaaagaatgctaag
cgtgccagtactgcagctgcacctttggctgcctgggtgaaagccaatattcagtattcc
catgtcttggaacgaattcatcctttggaaactgaacaggcaggattagaatcgaatctg
aagaaaactgaagacagaaaaaggaaactagaggagcttcttaattctgttggtcaaaag
gtatcagaactcaaagaaaaatttcagagcaggacttcagaagctgccaaacttgaggct
gaagtaagcaaggcacaagaaacaatcaaagctgcagaagtcttaattaatcagcttgac
agagaacataagagatggaatgcacaggttgtagagataacagaggaattagctactctt
cctaaaagagctcaacttgctgctgcatttattacatatctttctgctgctcctgaatct
ctgagaaaaacctgtttggaagaatggaccaagtcagctggtcttgagaaatttgatctg
aggagatttctttgtactgaaagtgagcagttaatttggaaaagtgaaggcctaccatca
gatgacctttccatagaaaatgctcttgtaatattacagagtcgagtgtgcccatttctt
atagatccttcttcccaagctacagagtggttaaaaacacatttgaaagactcacgttta
gaagttatcaatcagcaggatagtaactttatcacagctcttgaattagcagtacgtttt
gggaaaacccttattatacaagagatggatggtgtagaacctgttctttatccattattg
agacgagatctggttgctcaaggaccacgttatgtggtacaaataggtgacaaaattatt
gactacaatgaagaattccgcctctttttgtcaacaagaaacccaaatccttttattcca
ccggatgcagcttccattgttactgaggttaactttactacaacaagaagtggattacga
gggcagcttttagctttaaccattcagcatgagaaacctgatttagaagaacagaaaaca
aaactattacaacaggaagaagataagaaaatacagctagccaagctcgaagaatctctt
ctagagacacttgccacatctcaaggcaatattttggaaaataaggatttgattgagtct
ttgaatcagacaaaagcaagcagtgcacttattcaagagtcacttaaagaatcttacaaa
ctccaaatttcccttgatcaagaacgggatgcctatctccccctggctgagagtgccagc
aagatgtacttcattatttctgatttgtccaaaattaataacatgtaccgttttagtttg
gctgcttttctccgacttttccaacgagctctacaaaacaaacaggattctgaaaataca
gaacagagaatccagtcacttatcagctcattacaacatatggtatatgaatatatatgt
cgttgtctatttaaggctgatcagttgatgttcgctttgcattttgttcgaggcatgcat
cctgaactttttcaagaaaatgaatgggatacgtttacaggtgtggttgttggagacatg
ttacggaaagctgactctcaacaaaaaatacgtgatcagcttccgtcttggatagatcag
gaacgaagctgggccgtggcaacattaaagattgctctccccagtctttatcagaccctc
tgctttgaagatgcagctctgtggcgtacttattataataattcaatgtgtgagcaagag
tttccatctatccttgcaaagaaagtttccttatttcagcagattcttgtagtacaggcg
ctaagaccggacagattgcaaagtgccatggctctttttgcatgtaaaactctgggactg
aaagaggtgtccccactgcctctaaatctcaaacgtttatacaaagagacactggaaatt
gaacccatcttgataattatttctccgggtgctgatccttctcaggaacttcaagaacta
gctaatgctgaaagaagcggagagtgttatcaccaggttgccatgggtcaaggtcaagct
gatttagcaattcaaatgctaaaagaatgtgcccgcaatggagactggctctgtttgaag
aacttacatcttgtggtatcttggctgccagttctggaaaaggaattgaatactcttcaa
cctaaagatacctttcgtctttggctcactgcagaagttcatcccaactttactcctatt
ttactacagtcaagtctgaagataacatatgagtcacctccaggtttaaagaagaattta
atgcgtacttatgagtcttggactcctgagcaaattagcaaaaaagataatacacatcga
gctcatgctctcttcagtcttgcatggtttcatgctgcatgtcaagaaagaagaaactat
attcctcagggttggacaaagttttatgaattttctttatcagatcttcgggctgggtac
aacattattgacagactttttgatggtgccaaagatgtacaatgggaatttgtacatggt
ttacttgaaaatgctatttatggaggacgtatagacaactattttgaccttagagttctt
cagtcatacctgaagcagttttttaattcttcagttattgatgtattcaaccaaaggaac
aagaaaagcatttttccatattccgtatctctaccacaatcctgcagcattttggactat
cgtgctgtcattgagaaaattccagaggacgacaaacctagtttctttggtctgcctgcc
aatatcgctcgctcatctcagcgcatgatcagttctcaggttatttcacagttgaggatt
ttgggcagatccataacagctggttccaaatttgatagagaaatctggtctaatgaactt
tctcctgtcctcaatctctggaagaaactaaaccagaattcaaacctaatacatcagaaa
gtgcctcctcctaacgatcgacaaggatctccaatactgtcattcatcattcttgaacaa
tttaatgctattcgtttagtacaaagtgtccaccagtctcttgctgctctcagcaaagtc
atcagaggaactactttactgagttcagaagtacaaaaattggcaagtgctttattaaac
caaaagtgtcctctcgcatggcagagcaagtgggaaggcccagaagatcccttacaatac
ctgagaggtcttgttgcccgtgcccttgcaatacagaactgggtagataaagctgaaaaa
caggctcttctctctgaaacacttgacctatcagaacttttccatccagacacatttctt
aatgctcttcgccaggaaactgcaagggcagtgggtcgttctgtggatagccttaaattt
gtagcctcatggaaaggtcgactgcaagaagcaaagctacaaattaagatcagtggcttg
ttactagaaggatgtagttttgatggaaatcaactttctgaaaatcagcttgattctccc
agcgtgtcatcagtgctcccttgttttatgggctggattccacaggatgcatgtggtcca
tattctccggatgagtgcatctctttgcctgtttacacaagtgctgaaagggatcgtgtg
gttaccaatattgatgttccatgtgggggcaaccaagaccagtggattcagtgtggagca
gctctattcctaaaaaatcagtag

KEGG   Homo sapiens (human): 8655
Entry
8655              CDS       T01001                                 
Symbol
DYNLL1, DLC1, DLC8, DNCL1, DNCLC1, LC8, LC8a, PIN, hdlc1
Name
(RefSeq) dynein light chain LC8-type 1
  KO
K10418  dynein light chain LC8-type
Organism
hsa  Homo sapiens (human)
Pathway
hsa04814  Motor proteins
hsa04962  Vasopressin-regulated water reabsorption
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
  Element
N01295  Rab7-regulated microtubule minus-end directed transport
N01534  Dynein recruitment to the kinetochore
N01846  Retrograde axonal/dendrite transport, Dynein
N01847  Regulation of dynein-mediated retrograde transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    8655 (DYNLL1)
 09150 Organismal Systems
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    8655 (DYNLL1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    8655 (DYNLL1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    8655 (DYNLL1)
   04812 Cytoskeleton proteins [BR:hsa04812]
    8655 (DYNLL1)
Cilium and associated proteins [BR:hsa03037]
 Motile cilia and associated proteins
  Dynein arm
   8655 (DYNLL1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Dyneins
     8655 (DYNLL1)
SSDB
Motif
Pfam: Dynein_light
Other DBs
NCBI-GeneID: 8655
NCBI-ProteinID: NP_001032583
OMIM: 601562
HGNC: 15476
Ensembl: ENSG00000088986
Pharos: P63167(Tbio)
UniProt: P63167 Q6FGH9
Structure
LinkDB
Position
12:120469842..120498493
AA seq 89 aa
MCDRKAVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGR
NFGSYVTHETKHFIYFYLGQVAILLFKSG
NT seq 270 nt   +upstreamnt  +downstreamnt
atgtgcgaccgaaaggccgtgatcaaaaatgcggacatgtcggaagagatgcaacaggac
tcggtggagtgcgctactcaggcgctggagaaatacaacatagagaaggacattgcggct
catatcaagaaggaatttgacaagaagtacaatcccacctggcattgcatcgtggggagg
aacttcggtagttatgtgacacatgaaaccaaacacttcatctacttctacctgggccaa
gtggccattcttctgttcaaatctggttaa

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