Homo sapiens (human): 1487 Help Entry 1487              CDS       T01001                                  Symbol CTBP1, BARS, HADDTS Name (RefSeq) C-terminal binding protein 1   KO K04496   C-terminal binding protein [EC:1.1.1.428] Organism hsa  Homo sapiens (human) Pathway hsa04310   Wnt signaling pathway hsa04330   Notch signaling pathway hsa05200   Pathways in cancer hsa05220   Chronic myeloid leukemia Network nt06523  Epigenetic regulation by Polycomb complexes   Element N01577   Gene silencing by methylation of H3K27 and ubiquitination of H2AK119 Disease H01773   4p deletion syndrome H02619   Hypotonia, ataxia, developmental delay, and tooth enamel defect syndrome Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     1487 (CTBP1)    04330 Notch signaling pathway     1487 (CTBP1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     1487 (CTBP1)   09162 Cancer: specific types    05220 Chronic myeloid leukemia     1487 (CTBP1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     1487 (CTBP1) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.1  Acting on the CH-OH group of donors    1.1.1  With NAD+ or NADP+ as acceptor     1.1.1.428  4-methylthio 2-oxobutanoate reductase (NADH)      1487 (CTBP1) Membrane trafficking [BR:hsa04131]  Endocytosis   Macropinocytosis    Others     1487 (CTBP1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  2-Hacid_dh_C 2-Hacid_dh NAD_binding_2 XdhC_C RS_preATP-grasp-like F420_oxidored Motif Other DBs NCBI-GeneID:  1487 NCBI-ProteinID:  NP_001319 OMIM:  602618 HGNC:  2494 Ensembl:  ENSG00000159692 Pharos:  Q13363(Tbio) UniProt:  Q13363 X5D8Y5 Structure PDBPDBj LinkDB All DBs Position 4:complement(1211445..1250355) Genome browser AA seq 440 aa AA seqDB search MGSSHLLNKGLPLGVRPPIMNGPLHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQ EIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNV PAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGII GLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLN EHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFS QGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAAT HWASMDPAVVHPELNGAAYRYPPGVVGVAPTGIPAAVEGIVPSAMSLSHGLPPVAHPPHA PSPGQTVKPEADRDHASDQL NT seq 1323 nt NT seq  +upstreamnt  +downstreamnt atgggcagctcgcacttgctcaacaagggcctgccgcttggcgtccgacctccgatcatg aacgggcccctgcacccgcggcccctggtggcattgctggatggccgggactgcacagtg gagatgcccatcctgaaggacgtggccactgtggccttctgcgacgcgcagtccacgcag gagatccatgagaaggtcctgaacgaggctgtgggggccctgatgtaccacaccatcact ctcaccagggaggacctggagaagttcaaagccctccgcatcatcgtccggattggcagt ggttttgacaacatcgacatcaagtcggccggggatttaggcattgccgtctgcaacgtg cccgcggcgtctgtggaggagacggccgactcgacgctgtgccacatcctgaacctgtac cggcgggccacctggctgcaccaggcgctgcgggagggcacacgagtccagagcgtcgag cagatccgcgaggtggcgtccggcgctgccaggatccgcggggagaccttgggcatcatc ggacttggtcgcgtggggcaggcagtggcgctgcgggccaaggccttcggcttcaacgtg ctcttctacgacccttacttgtcggatggcgtggagcgggcgctggggctgcagcgtgtc agcaccctgcaggacctgctcttccacagcgactgcgtgaccctgcactgcggcctcaac gagcacaaccaccacctcatcaacgacttcaccgtcaagcagatgagacaaggggccttc ctggtgaacacagcccggggtggcctggtggatgagaaggcgctggcccaggccctgaag gagggccggatccgcggcgcggccctggatgtgcacgagtcggaacccttcagctttagc cagggccctctgaaggatgcacccaacctcatctgcaccccccatgctgcatggtacagc gagcaggcatccatcgagatgcgagaggaggcggcacgggagatccgcagagccatcaca ggccggatcccagacagcctgaagaactgtgtcaacaaggaccatctgacagccgccacc cactgggccagcatggaccccgccgtcgtgcaccctgagctcaatggggctgcctatagg taccctccgggcgtggtgggcgtggcccccactggcatcccagctgctgtggaaggtatc gtccccagcgccatgtccctgtcccacggcctgccccctgtggcccacccgccccacgcc ccttctcctggccaaaccgtcaagcccgaggcggatagagaccacgccagtgaccagttg tag

Homo sapiens (human): 1488 Help Entry 1488              CDS       T01001                                  Symbol CTBP2 Name (RefSeq) C-terminal binding protein 2   KO K04496   C-terminal binding protein [EC:1.1.1.428] Organism hsa  Homo sapiens (human) Pathway hsa04310   Wnt signaling pathway hsa04330   Notch signaling pathway hsa05200   Pathways in cancer hsa05220   Chronic myeloid leukemia Network nt06523  Epigenetic regulation by Polycomb complexes   Element N01577   Gene silencing by methylation of H3K27 and ubiquitination of H2AK119 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     1488 (CTBP2)    04330 Notch signaling pathway     1488 (CTBP2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     1488 (CTBP2)   09162 Cancer: specific types    05220 Chronic myeloid leukemia     1488 (CTBP2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     1488 (CTBP2) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.1  Acting on the CH-OH group of donors    1.1.1  With NAD+ or NADP+ as acceptor     1.1.1.428  4-methylthio 2-oxobutanoate reductase (NADH)      1488 (CTBP2) Membrane trafficking [BR:hsa04131]  Endocytosis   Macropinocytosis    Others     1488 (CTBP2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  2-Hacid_dh_C 2-Hacid_dh NAD_binding_2 Motif Other DBs NCBI-GeneID:  1488 NCBI-ProteinID:  NP_001077383 OMIM:  602619 HGNC:  2495 Ensembl:  ENSG00000175029 Pharos:  P56545(Tbio) UniProt:  P56545 Structure PDBPDBj LinkDB All DBs Position 10:complement(124984317..125162463) Genome browser AA seq 445 aa AA seqDB search MALVDKHKVKRQRLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFC DAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELG IAVCNIPSAAVEETADSTICHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRG ETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVS LHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHES EPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKE FFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGGIPVTHNLPTV AHPSQAPSPNQPTKHGDNREHPNEQ NT seq 1338 nt NT seq  +upstreamnt  +downstreamnt atggcccttgtggataagcacaaagtcaagagacagcgattggacagaatttgtgaaggt atccgcccccagatcatgaacggccccctgcacccccgccccctggtggcgctgctggac ggccgcgactgcactgtggagatgcccatcctgaaggacctggccactgtggccttctgt gacgcgcagtcgacgcaggaaatccacgagaaggttctaaacgaagccgtgggcgccatg atgtaccacaccatcaccctcaccagggaggacctggagaagttcaaggccctgagagtg atcgtgcggataggcagtggctatgacaacgtggacatcaaggctgccggcgagctcgga attgccgtgtgcaacatcccgtctgcagccgtggaagagacagcggactctaccatctgc cacatcctcaacctgtaccggaggaacacgtggctgtaccaggcactgcgggaaggcacg cgggttcagagcgtggagcagatccgcgaggtggcctcgggagcggcccgcatccgtggg gagacgctgggcctcattggctttggtcgcacggggcaggcggttgcagttcgagccaag gcctttggattcagcgtcatattttatgacccctacttgcaggatgggatcgagcggtcc ctgggcgtgcagagggtctacaccctgcaggatttgctgtatcagagcgactgcgtctcc ttgcactgcaatctcaacgaacataaccaccacctcatcaatgactttaccataaagcag atgaggcagggagcattccttgtgaacgcagcccgtggcggcctggtggacgagaaagcc ttagcacaagccctcaaggagggcaggatacgaggggcagccctcgacgtgcatgagtca gagcccttcagctttgctcagggtccgttgaaagatgccccgaatctcatctgcactcct cacactgcctggtacagtgagcaggcgtcactggagatgagggaggcagctgccaccgag atccgccgagccatcacaggtcgcatcccagaaagcttaagaaattgtgtgaacaaggaa ttctttgtcacatcagcgccttggtcagtaatagaccagcaagcaattcatcctgagctc aatggtgccacatacagatatccgccaggcatcgtgggtgtggctccaggaggacttcct gcagccatggaagggatcatccctggaggcatcccagtgactcacaacctcccgacagtg gcacatccttcccaagcgccctctcccaaccagcccacaaaacacggggacaatcgagag caccccaacgagcaatag

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