Homo sapiens (human): 1794
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Entry
1794 CDS
T01001
Symbol
DOCK2, IMD40
Name
(RefSeq) dedicator of cytokinesis 2
KO
K12367
dedicator of cytokinesis protein 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04062
Chemokine signaling pathway
Disease
H00093
Combined immunodeficiency
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04062 Chemokine signaling pathway
1794 (DOCK2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
1794 (DOCK2)
Membrane trafficking [BR:
hsa04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
1794 (DOCK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TPR_DOCK
DOCK_N
DOCK-C2
DHR-2_Lobe_C
DHR-2_Lobe_A
DHR-2_Lobe_B
SH3_2
SH3_1
SH3_9
DUF1539
Motif
Other DBs
NCBI-GeneID:
1794
NCBI-ProteinID:
NP_004937
OMIM:
603122
HGNC:
2988
Ensembl:
ENSG00000134516
UniProt:
Q92608
Q5XG91
Structure
PDB
PDBj
LinkDB
All DBs
Position
5:169637275..170083382
Genome browser
AA seq
1830 aa
AA seq
DB search
MAPWRKADKERHGVAIYNFQGSGAPQLSLQIGDVVRIQETCGDWYRGYLIKHKMLQGIFP
KSFIHIKEVTVEKRRNTENIIPAEIPLAQEVTTTLWEWGSIWKQLYVASKKERFLQVQSM
MYDLMEWRSQLLSGTLPKDELKELKQKVTSKIDYGNKILELDLIVRDEDGNILDPDNTSV
ISLFHAHEEATDKITERIKEEMSKDQPDYAMYSRISSSPTHSLYVFVRNFVCRIGEDAEL
FMSLYDPNKQTVISENYLVRWGSRGFPKEIEMLNNLKVVFTDLGNKDLNRDKIYLICQIV
RVGKMDLKDTGAKKCTQGLRRPFGVAVMDITDIIKGKAESDEEKQHFIPFHPVTAENDFL
HSLLGKVIASKGDSGGQGLWVTMKMLVGDIIQIRKDYPHLVDRTTVVARKLGFPEIIMPG
DVRNDIYITLLQGDFDKYNKTTQRNVEVIMCVCAEDGKTLPNAICVGAGDKPMNEYRSVV
YYQVKQPRWMETVKVAVPIEDMQRIHLRFMFRHRSSLESKDKGEKNFAMSYVKLMKEDGT
TLHDGFHDLVVLKGDSKKMEDASAYLTLPSYRHHVENKGATLSRSSSSVGGLSVSSRDVF
SISTLVCSTKLTQNVGLLGLLKWRMKPQLLQENLEKLKIVDGEEVVKFLQDTLDALFNIM
MEHSQSDEYDILVFDALIYIIGLIADRKFQHFNTVLEAYIQQHFSATLAYKKLMTVLKTY
LDTSSRGEQCEPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFESINNL
MKSQYKTTILLQVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQKVQSMN
EIVQSNLFKKQECRDILLPVITKELKELLEQKDDMQHQVLERKYCVELLNSILEVLSYQD
AAFTYHHIQEIMVQLLRTVNRTVITMGRDHILISHFVACMTAILNQMGDQHYSFYIETFQ
TSSELVDFLMETFIMFKDLIGKNVYPGDWMAMSMVQNRVFLRAINKFAETMNQKFLEHTN
FEFQLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQN
KICFIPGMVGPILEMTLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEV
EGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKLLDYRGVMTDESKDNR
MSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCAS
QVMQTGQQHPQTHRQLKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQ
NLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRGKEYERREDFQMQLMT
QFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQ
RFHYSRPVRRGTVDPENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIE
TMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAKYEKAFFTEEYVRDHP
EDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVR
EMPDFDDRRVGRPRSMLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQ
EEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSRKHEFMSDTNLSEHAA
IPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTR
KKVNQFFKTMLASKSAEEGKQIPDSLSTDL
NT seq
5493 nt
NT seq
+upstream
nt +downstream
nt
atggccccctggcgcaaagctgacaaggagcggcacggcgtggccatatacaacttccaa
ggcagcggagccccccagctctccctgcagatcggcgatgtggtgcgaatacaggagacg
tgtggagactggtataggggatacctcataaagcacaaaatgttacagggcatttttcct
aagtcatttatccacatcaaggaagtgacagttgagaaaagaagaaatactgagaacatc
attcctgcagaaattcctctggcacaagaagtgacaacgacactttgggaatggggaagc
atctggaaacaactctatgtggccagcaaaaaggagcgttttctccaggtgcagtccatg
atgtacgatctgatggagtggaggtcccagcttctctcaggaaccttacccaaggatgag
ctgaaggaactgaagcagaaagtcacgtccaaaattgactatggcaacaaaatccttgag
cttgatttgattgtcagagatgaagacggaaatatcttggaccctgataataccagtgtc
atcagcttgttccatgcacatgaggaagcaactgataaaatcacagagcgtatcaaagaa
gaaatgtcaaaagaccagccagattatgcaatgtattcccggatctcctcatcccccacc
catagcctctatgtgtttgtgagaaactttgtgtgcagaattggggaagatgctgagctc
ttcatgtctctctacgaccccaacaagcaaacggtcataagtgagaactacctagtgcga
tggggcagccggggcttccctaaggagattgagatgctcaacaatctgaaggtggtcttc
acggatcttggaaacaaagacctcaacagggataaaatttacttgatttgtcaaatagtc
cgggtcggcaagatggatcttaaggatactggtgcaaagaagtgcacgcagggactgagg
aggccctttggggtggcagttatggatataacagacatcatcaaggggaaagcagagagt
gatgaagaaaagcagcacttcattccttttcacccggttacagctgagaatgacttccta
cacagcctgctgggcaaagtcatagcctccaagggggacagtggagggcaaggcctctgg
gtgaccatgaagatgctggtgggtgacatcattcagattcgcaaggactatccacacctg
gtggacaggaccaccgtggtggccaggaagctgggattcccagagatcatcatgccaggg
gatgtcaggaacgacatctacattactctcttacaaggtgactttgacaagtacaacaag
accacacagaggaatgtggaagtcatcatgtgtgtgtgcgcggaggatggcaaaacgctg
cctaatgcaatttgcgtgggagcaggggacaagcccatgaatgagtatcgctccgttgtg
tactatcaagtcaaacagccacgctggatggaaacagtcaaggtggctgtccctattgaa
gacatgcagaggatccatctgcgattcatgtttcgacatcggtcatctctggaatctaaa
gataaaggagaaaagaactttgccatgtcctatgtgaagctgatgaaagaagatgggact
actctacacgatggattccatgacttagttgtcctcaagggggacagcaagaagatggag
gatgccagcgcatacctgacccttccttcttatcgacaccatgtggaaaacaagggggcc
acgctgagcaggagctccagcagtgttggggggctttctgtcagctcccgggatgtgttc
tccatttccaccctggtgtgctccacaaagctcactcagaatgtgggcttgctgggtttg
ctgaagtggcgtatgaagcctcaactgctacaggagaatttagaaaagttgaagattgtg
gatggagaggaagtggtgaagtttctccaggatactctggatgccctcttcaacatcatg
atggagcattctcaaagtgatgaatatgacatcctcgtctttgatgccttgatttacata
ataggactcattgcagaccggaaatttcagcatttcaacaccgttctggaggcttacatc
caacagcatttcagtgcgaccttggcttacaagaaattgatgacagtgctgaagacttac
ttggatacctccagcagaggggagcaatgtgagccaatcctaagaacgctgaaggctttg
gaatatgtgttcaagttcattgttcggtcgaggacattattttcacagctttatgaaggc
aaagaacagatggagtttgaagaatccatgagacggctctttgaatccatcaacaatctg
atgaaaagtcaatacaaaactaccatccttttgcaggtggcggctttgaaatacatccca
tctgtcctgcatgatgtagaaatggtctttgatgcgaagttactcagccaactcctgtat
gagttctacacctgcatccctcctgtgaaactccagaagcagaaagtacagtctatgaat
gagatagtccagagcaacctctttaaaaagcaagaatgccgggacattctgcttcctgtc
atcaccaaagagctgaaggagctgctggagcagaaggatgacatgcaacaccaggtcctg
gagaggaagtactgcgttgaattgctcaacagcatcttggaagtccttagctaccaggat
gcggccttcacctaccaccatatccaggagatcatggtccagctgctgcggacagtgaac
cggacagtcatcaccatgggccgggatcacattctgattagtcactttgtggcatgtatg
acagccatcttaaaccagatgggtgaccagcactactccttctacattgagaccttccag
accagctctgaacttgtggacttcttgatggagaccttcatcatgttcaaggacctcatt
ggaaagaacgtgtaccctggagactggatggccatgagcatggttcaaaacagggtcttc
ctgagagctatcaacaagtttgcagaaaccatgaaccagaagttcctagaacacacgaac
tttgagttccagctgtggaacaactattttcatctggcagtggcttttatcacccaggat
tctctgcagctggagcagttctcacacgccaaatacaacaaaatcctgaataagtatggg
gacatgagacggctaattggcttctccatccgtgatatgtggtacaagcttggtcagaac
aaaatctgcttcatcccaggcatggtaggacctatattagagatgacacttatccctgag
gctgagctccggaaagccaccataccaatcttcttcgacatgatgctgtgtgaatatcaa
agaagtggggatttcaaaaagtttgaaaacgaaatcatcctgaagctggaccacgaggta
gaagggggccgaggcgacgagcagtacatgcagctcctggagtcaatcctgatggaatgt
gctgcagagcacccaaccattgccaagtcggtggagaacttcgtgaacctggtcaaaggc
ctcctggagaagctgctggattaccggggtgtgatgacagatgagagcaaagacaaccgc
atgagctgcaccgtgaacctgctgaatttctacaaagataacaacagggaggagatgtac
ataaggtacctgtacaaactccgcgatcttcacctggactgtgacaattacacagaggct
gcctacacgctccttctccacacctggcttctcaagtggtcggatgagcagtgtgcatca
caggtcatgcagacaggccagcagcacccccagacacaccggcagctgaaggagacgctc
tacgagaccatcataggctactttgacaaaggaaagatgtgggaagaggccataagtctg
tgcaaggagctggcggaacagtacgagatggagatctttgactatgagctgctcagccag
aacctgatccagcaggcaaaattctatgaaagcatcatgaaaatcctcaggcccaaacca
gactactttgctgttggatactacggccagggattcccctccttcctgcggaacaaagtg
ttcatctaccgcgggaaggaatatgagcgaagagaagatttccagatgcagctgatgacc
cagttccccaatgcagagaagatgaacaccacctctgccccgggagatgatgtgaagaat
gccccaggccagtatatccagtgcttcactgtccagcctgtcttggatgaacatcccagg
ttcaagaataagccagtgcctgaccagattataaacttctacaaatccaactacgtgcaa
aggttccactactcccggcccgtgcgcagggggaccgtagacccagagaatgagtttgct
tccatgtggattgagagaacctccttcgtgactgcatacaagctgccggggatcctgcgc
tggtttgaggtggtgcacatgtcgcagaccacaattagtcctctggagaatgccatagaa
accatgtccacggccaatgagaagatcctgatgatgataaaccagtaccagagtgatgag
accctccccatcaacccactctccatgctcctgaacgggattgtggaccctgctgtcatg
ggaggcttcgccaagtatgagaaggccttcttcactgaagagtatgtcagggaccaccct
gaggaccaggacaagctgacccacctcaaggacctgattgcatggcagatccccttcttg
ggagctgggattaagatccatgagaaaagggtgtcagataacttgcgacccttccatgac
cggatggaggaatgtttcaagaacctgaaaatgaaggtggagaaggagtacggtgtccga
gagatgcctgactttgacgacaggagagtgggccgtcccaggtctatgctgcgctcatac
agacagatgtccatcatctctctggcttccatgaattctgactgcagcacccccagcaag
cctacctcagagagctttgacctggaattagcatcacccaagacgccgagagtggagcag
gaggaaccgatctccccggggagcaccctgcctgaggtcaagctgcggaggtccaagaag
aggacaaagagaagcagcgtagtttttgcggatgagaaagcagctgcagagtcggacctg
aagcggctttccaggaagcatgagttcatgagtgacaccaacctctcggagcatgcggcc
atccccctcaaggcgtctgtcctctctcaaatgagctttgccagccagtccatgcctacc
atcccagccctggcgctctcagtggcaggcatccctgggttggatgaggccaacacatct
ccccgcctcagccagaccttcctccaactctcagatggtgacaagaagacactcacacgg
aagaaggtcaatcagttcttcaagacaatgctggccagcaaatcggctgaagaaggcaaa
cagatcccagactcgctgtccacggacctgtga
DBGET
integrated database retrieval system
