Homo sapiens (human): 1813 Help Entry 1813              CDS       T01001                                  Symbol DRD2, D2DR, D2R Name (RefSeq) dopamine receptor D2   KO K04145   dopamine receptor D2 Organism hsa  Homo sapiens (human) Pathway hsa04015   Rap1 signaling pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04081   Hormone signaling hsa04082   Neuroactive ligand signaling hsa04540   Gap junction hsa04728   Dopaminergic synapse hsa05012   Parkinson disease hsa05030   Cocaine addiction hsa05034   Alcoholism Network nt06544  Neuroactive ligand signaling   Element N01898   Dopamine-DRD-GNAI/O signaling pathway Drug target Acepromazine (DG00870):  D02604 D07065 Acetophenazine (DG00878):  D00788 Alentemol hydrobromide:  D02634 Alizapride (DG00058):  D07102 D07563 Amisulpride:  D07310<US> Aplindore fumarate:  D03214 Apomorphine (DG00486):  D02004<JP/US> D07460 Aripiprazole (DG00906):  D01164<JP/US> D10355 D10364<US> D10516<JP/US> Asenapine (DG03100):  D02995<JP/US> D11769<US> Benperidol:  D02627 Bifeprunox (DG01304):  D06566 D06567 Blonanserin:  D01176<JP> Brexpiprazole (DG03365):  D10309<JP/US> D13183 Brilaroxazine (DG03296):  D12813 D12814 Bromocriptine (DG00452):  D00780<JP/US> D03165 Bromopride:  D07101 Bromperidol (DG00890):  D01101<JP> D02626 Buspirone (DG00913):  D00702<US> D07593 Butaclamol hydrochloride:  D02641 Cabergoline:  D00987<JP/US> Cariprazine (DG01305):  D09876<US> D09997 Carphenazine maleate:  D02644 Carvotroline hydrochloride:  D02645 Chlorpromazine (DG00867):  D00270 D00789<JP/US> D03274 D04034<JP> D09819 Chlorprothixene (DG00894):  D00790 D02162 D07686 D07687 Ciladopa hydrochloride:  D03494 Clebopride (DG00059):  D01742 D03534 Clocapramine (DG01313):  D02371<JP> D07718 Clopenthixol:  D02613 Dexpramipexole (DG01331):  D09886 D09887 Dihydroergocryptine (DG01329):  D07835 Dihydroergocryptine mesylate:  D07836 Domperidone (DG00057):  D01745<JP> D07868 Dopamine (DG00213):  D00633<JP/US> D07870 Dopexamine (DG00222):  D03891 D03892 Dordaviprone (DG03280):  D12733 D12734<US> Droperidol:  D00308<JP/US> Etilevodopa:  D04097 Flupentixol (DG00893):  D01044 D02236 D07976 Fluphenazine (DG00874):  D00791<US> D00792 D00793<JP/US> D02163<JP> D07977 Foslevodopa:  D11839 Haloperidol (DG00885):  D00136<JP/US> D01898<JP/US> D08035<US> Ibopamine (DG00223):  D04488 D08057 Iloperidone:  D02666<US> Itopride (DG01395):  D02729<JP> D08094 Lergotrile (DG01319):  D04693 D04694 Levodopa:  D00059<JP/US> Levomepromazine (DG00868):  D00403 D01520 D02248<JP> Levosulpiride:  D07312 Lisuride (DG00453):  D01462 D08132 Loxapine (DG00897):  D00794<US> D02340 D08148 Lumateperone (DG02937):  D11169 D11170<US> Lurasidone:  D04820<JP/US> Mazapertine succinate:  D02670 Melperone (DG00887):  D07309 D08172 Mesoridazine (DG00883):  D00795 D02671 Methoxypromazine maleate:  D02605 Metoclopramide (DG00055):  D00726<JP> D02213<JP> D05008<US> Metopimazine:  D05010 Milsaperidone:  D13099 Molindone (DG00891):  D00796<US> D08226 Moperone (DG00888):  D01105 D02623 Mosapramine (DG00905):  D01548<JP> D08235 Naxagolide hydrochloride:  D05124 Nemonapride:  D01468<JP> Ocaperidone:  D02675 Olanzapine (DG00898):  D00454<JP/US> D06623<US> Opipramol (DG00930):  D01477 D08297 Oxiperomide:  D02676 Paliperidone (DG00907):  D05339<JP/US> D05340<JP/US> Pardoprunox (DG01324):  D09366 D09397 Perazine (DG00881):  D01412 D01860 D02608 Pergolide (DG00861):  D00502<JP> D08339 Periciazine:  D01485<JP> Perospirone hydrochloride hydrate:  D02372<JP> Perphenazine (DG00875):  D00503<JP/US> D02037<JP> D04038<JP> D04965<JP> D08341 D08342 Pimozide:  D00560<US> Pipamperone (DG00889):  D01482<JP> D02622 Pipotiazine (DG00884):  D02680 D08385 Piquindone hydrochloride:  D02681 Piribedil:  D07305 Pramipexole (DG00863):  D00559<JP/US> D05575 Pridopidine (DG01325):  D09953 D09954 Prochlorperazine (DG00876):  D00479<JP/US> D00493<US> D02022<JP> D02609<US> Promazine (DG00869):  D00797 D08430 Quetiapine (DG00899):  D00458<JP/US> D08456 Quinagolide (DG00454):  D07217 D08457 Quinelorane hydrochloride:  D05677 Quinpirole hydrochloride:  D05682 Raclopride C11:  D05690 Remoxipride (DG00902):  D02682 D02683 Risperidone:  D00426<JP/US> Ropinirole (DG00862):  D00784<JP/US> D08489 Rotigotine:  D05768<JP/US> Sarizotan hydrochloride:  D05804 Sertindole:  D00561 Sibenadet hydrochloride:  D05832 Spiperone:  D01051<JP> Sulpiride:  D01226<JP> Sultopride (DG00900):  D02208<JP> D08549 Talipexole (DG01326):  D01505 D08558 Terguride:  D01348 Thiethylperazine (DG01102):  D01130 D02354 D02610 Thioproperazine (DG00879):  D01447 D08585 Thioridazine (DG00882):  D00373 D00798<US> Tiapride (DG00901):  D01522<JP> D08590 Timiperone:  D02035<JP> Tiospirone hydrochloride:  D02688 Tiotixene (DG00895):  D00374<US> D02612 Trazpiroben:  D11982 Trifluoperazine (DG00877):  D00799<US> D01448 D08636 Trifluperidol (DG00886):  D02625 D08637 Triflupromazine (DG00871):  D00390 D00800 Zicronapine (DG01539):  D10329 D10495 Ziprasidone (DG00892):  D01939<US> D02100<US> D08687 Zotepine:  D01321<JP> Zuclopenthixol (DG00896):  D03556 D08691 D08692 D08693 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     1813 (DRD2)    04024 cAMP signaling pathway     1813 (DRD2)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     1813 (DRD2)    04082 Neuroactive ligand signaling     1813 (DRD2)    04081 Hormone signaling     1813 (DRD2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     1813 (DRD2)  09150 Organismal Systems   09156 Nervous system    04728 Dopaminergic synapse     1813 (DRD2)  09160 Human Diseases   09164 Neurodegenerative disease    05012 Parkinson disease     1813 (DRD2)   09165 Substance dependence    05030 Cocaine addiction     1813 (DRD2)    05034 Alcoholism     1813 (DRD2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     1813 (DRD2) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Dopamine     1813 (DRD2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srv RIFIN Stevor zf-LITAF-like Motif Other DBs NCBI-GeneID:  1813 NCBI-ProteinID:  NP_000786 OMIM:  126450 HGNC:  3023 Ensembl:  ENSG00000149295 UniProt:  P14416 Structure PDBPDBj LinkDB All DBs Position 11:complement(113409605..113475398) Genome browser AA seq 443 aa AA seqDB search MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA VNPIIYTTFNIEFRKAFLKILHC NT seq 1332 nt NT seq  +upstreamnt  +downstreamnt atggatccactgaatctgtcctggtatgatgatgatctggagaggcagaactggagccgg cccttcaacgggtcagacgggaaggcggacagaccccactacaactactatgccacactg ctcaccctgctcatcgctgtcatcgtcttcggcaacgtgctggtgtgcatggctgtgtcc cgcgagaaggcgctgcagaccaccaccaactacctgatcgtcagcctcgcagtggccgac ctcctcgtcgccacactggtcatgccctgggttgtctacctggaggtggtaggtgagtgg aaattcagcaggattcactgtgacatcttcgtcactctggacgtcatgatgtgcacggcg agcatcctgaacttgtgtgccatcagcatcgacaggtacacagctgtggccatgcccatg ctgtacaatacgcgctacagctccaagcgccgggtcaccgtcatgatctccatcgtctgg gtcctgtccttcaccatctcctgcccactcctcttcggactcaataacgcagaccagaac gagtgcatcattgccaacccggccttcgtggtctactcctccatcgtctccttctacgtg cccttcattgtcaccctgctggtctacatcaagatctacattgtcctccgcagacgccgc aagcgagtcaacaccaaacgcagcagccgagctttcagggcccacctgagggctccacta aagggcaactgtactcaccccgaggacatgaaactctgcaccgttatcatgaagtctaat gggagtttcccagtgaacaggcggagagtggaggctgcccggcgagcccaggagctggag atggagatgctctccagcaccagcccacccgagaggacccggtacagccccatcccaccc agccaccaccagctgactctccccgacccgtcccaccatggtctccacagcactcccgac agccccgccaaaccagagaagaatgggcatgccaaagaccaccccaagattgccaagatc tttgagatccagaccatgcccaatggcaaaacccggacctccctcaagaccatgagccgt aggaagctctcccagcagaaggagaagaaagccactcagatgctcgccattgttctcggc gtgttcatcatctgctggctgcccttcttcatcacacacatcctgaacatacactgtgac tgcaacatcccgcctgtcctgtacagcgccttcacgtggctgggctatgtcaacagcgcc gtgaaccccatcatctacaccaccttcaacattgagttccgcaaggccttcctgaagatc ctccactgctga

Homo sapiens (human): 1814 Help Entry 1814              CDS       T01001                                  Symbol DRD3, D3DR, ETM1, FET1 Name (RefSeq) dopamine receptor D3   KO K04146   dopamine receptor D3 Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04081   Hormone signaling hsa04082   Neuroactive ligand signaling hsa04728   Dopaminergic synapse Network nt06544  Neuroactive ligand signaling   Element N01898   Dopamine-DRD-GNAI/O signaling pathway Disease H01577   Essential tremor H01649   Schizophrenia Drug target Amisulpride:  D07310<US> Aplindore fumarate:  D03214 Aripiprazole (DG00906):  D01164<JP/US> D10355 D10364<US> D10516<JP/US> Blonanserin:  D01176<JP> Captodiame:  D07316 Dexpramipexole (DG01331):  D09886 D09887 Dopamine (DG00213):  D00633<JP/US> D07870 Dopexamine (DG00222):  D03891 D03892 Etilevodopa:  D04097 Foslevodopa:  D11839 Levodopa:  D00059<JP/US> Lisuride (DG00453):  D01462 D08132 Olanzapine (DG00898):  D00454<JP/US> D06623<US> Oxiperomide:  D02676 Pardoprunox (DG01324):  D09366 D09397 Piribedil:  D07305 Pramipexole (DG00863):  D00559<JP/US> D05575 Quinpirole hydrochloride:  D05682 Ropinirole (DG00862):  D00784<JP/US> D08489 Tiotixene (DG00895):  D00374<US> D02612 Trazpiroben:  D11982 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     1814 (DRD3)    04082 Neuroactive ligand signaling     1814 (DRD3)    04081 Hormone signaling     1814 (DRD3)  09150 Organismal Systems   09156 Nervous system    04728 Dopaminergic synapse     1814 (DRD3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     1814 (DRD3) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Dopamine     1814 (DRD3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7tm_4 Motif Other DBs NCBI-GeneID:  1814 NCBI-ProteinID:  NP_000787 OMIM:  126451 HGNC:  3024 Ensembl:  ENSG00000151577 UniProt:  P35462 A8K8E4 X5D2G4 Structure PDBPDBj LinkDB All DBs Position 3:complement(114127580..114199407) Genome browser AA seq 400 aa AA seqDB search MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC NT seq 1203 nt NT seq  +upstreamnt  +downstreamnt atggcatctctgagccagctgagtggccacctgaactacacctgtggggcagagaactcc acaggtgccagccaggcccgcccacatgcctactatgccctctcctactgcgcgctcatc ctggccatcgtcttcggcaatggcctggtgtgcatggctgtgctgaaggagcgggccctg cagactaccaccaactacttagtagtgagcctggctgtggcagacttgctggtggccacc ttggtgatgccctgggtggtatacctggaggtgacaggtggagtctggaatttcagccgc atttgctgtgatgtttttgtcaccctggatgtcatgatgtgtacagccagcatccttaat ctctgtgccatcagcatagacaggtacactgcagtggtcatgcccgttcactaccagcat ggcacgggacagagctcctgtcggcgcgtggccctcatgatcacggccgtctgggtactg gcctttgctgtgtcctgccctcttctgtttggctttaataccacaggggaccccactgtc tgctccatctccaaccctgattttgtcatctactcttcagtggtgtccttctacctgccc tttggagtgactgtccttgtctatgccagaatctatgtggtgctgaaacaaaggagacgg aaaaggatcctcactcgacagaacagtcagtgcaacagtgtcaggcctggcttcccccag caaaccctctctcctgacccggcacatctggagctgaagcgttactacagcatctgccag gacactgccttgggtggaccaggcttccaagaaagaggaggagagttgaaaagagaggag aagactcggaattccctgagtcccaccatagcgcccaagctcagcttagaagttcgaaaa ctcagcaatggcagattatcgacatctttgaagctggggcccctgcaacctcggggagtg ccacttcgggagaagaaggcaacccaaatggtggccattgtgcttggggccttcattgtc tgctggctgcccttcttcttgacccatgttctcaatacccactgccagacatgccacgtg tccccagagctttacagtgccacgacatggctgggctacgtgaatagcgccctcaaccct gtgatctataccaccttcaatatcgagttccggaaagccttcctcaagatcctgtcttgc tga

Homo sapiens (human): 1815 Help Entry 1815              CDS       T01001                                  Symbol DRD4, D4DR Name (RefSeq) dopamine receptor D4   KO K04147   dopamine receptor D4 Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04081   Hormone signaling hsa04082   Neuroactive ligand signaling hsa04728   Dopaminergic synapse Network nt06544  Neuroactive ligand signaling   Element N01898   Dopamine-DRD-GNAI/O signaling pathway Disease H01895   Attention deficit hyperactivity disorder (ADHD) Drug target Clozapine:  D00283<JP/US> Dexpramipexole (DG01331):  D09886 D09887 Dopamine (DG00213):  D00633<JP/US> D07870 Dopexamine (DG00222):  D03891 D03892 Etilevodopa:  D04097 Fananserin:  D02656 Foslevodopa:  D11839 Levodopa:  D00059<JP/US> Lisuride (DG00453):  D01462 D08132 Olanzapine (DG00898):  D00454<JP/US> D06623<US> Oxiperomide:  D02676 Pramipexole (DG00863):  D00559<JP/US> D05575 Ropinirole (DG00862):  D00784<JP/US> D08489 Sonepiprazole mesylate:  D05891 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     1815 (DRD4)    04082 Neuroactive ligand signaling     1815 (DRD4)    04081 Hormone signaling     1815 (DRD4)  09150 Organismal Systems   09156 Nervous system    04728 Dopaminergic synapse     1815 (DRD4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     1815 (DRD4) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Dopamine     1815 (DRD4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx Motif Other DBs NCBI-GeneID:  1815 NCBI-ProteinID:  NP_000788 OMIM:  126452 HGNC:  3025 Ensembl:  ENSG00000069696 UniProt:  P21917 Structure PDBPDBj LinkDB All DBs Position 11:637269..640706 Genome browser AA seq 419 aa AA seqDB search MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC NT seq 1260 nt NT seq  +upstreamnt  +downstreamnt atggggaaccgcagcaccgcggacgcggacgggctgctggctgggcgcgggccggccgcg ggggcatctgcgggggcatctgcggggctggctgggcagggcgcggcggcgctggtgggg ggcgtgctgctcatcggcgcggtgctcgcggggaactcgctcgtgtgcgtgagcgtggcc accgagcgcgccctgcagacgcccaccaactccttcatcgtgagcctggcggccgccgac ctcctcctcgctctcctggtgctgccgctcttcgtctactccgaggtccagggtggcgcg tggctgctgagcccccgcctgtgcgacgccctcatggccatggacgtcatgctgtgcacc gcctccatcttcaacctgtgcgccatcagcgtggacaggttcgtggccgtggccgtgccg ctgcgctacaaccggcagggtgggagccgccggcagctgctgctcatcggcgccacgtgg ctgctgtccgcggcggtggcggcgcccgtactgtgcggcctcaacgacgtgcgcggccgc gaccccgccgtgtgccgcctggaggaccgcgactacgtggtctactcgtccgtgtgctcc ttcttcctaccctgcccgctcatgctgctgctctactgggccacgttccgcggcctgcag cgctgggaggtggcacgtcgcgccaagctgcacggccgcgcgccccgccgacccagcggc cctggcccgccttcccccacgccacccgcgccccgcctcccccaggacccctgcggcccc gactgtgcgccccccgcgcccggccttccccggggtccctgcggccccgactgtgcgccc gccgcgcccagcctcccccaggacccctgcggccccgactgtgcgccccccgcgcccggc ctccccccggacccctgcggctccaactgtgctccccccgacgccgtcagagccgccgcg ctcccaccccagactccaccgcagacccgcaggaggcggcgtgccaagatcaccggccgg gagcgcaaggccatgagggtcctgccggtggtggtcggggccttcctgctgtgctggacg cccttcttcgtggtgcacatcacgcaggcgctgtgtcctgcctgctccgtgcccccgcgg ctggtcagcgccgtcacctggctgggctacgtcaacagcgccctcaaccccgtcatctac actgtcttcaacgccgagttccgcaacgtcttccgcaaggccctgcgtgcctgctgctga

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