Homo sapiens (human): 192111
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Entry
192111 CDS
T01001
Symbol
PGAM5, BXLBV68
Name
(RefSeq) PGAM family member 5, mitochondrial serine/threonine protein phosphatase
KO
K15637
serine/threonine-protein phosphatase PGAM5 [EC:
3.1.3.16
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04137
Mitophagy - animal
hsa04217
Necroptosis
hsa04668
TNF signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
192111 (PGAM5)
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
192111 (PGAM5)
09143 Cell growth and death
04217 Necroptosis
192111 (PGAM5)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
192111 (PGAM5)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
His_Phos_1
Motif
Other DBs
NCBI-GeneID:
192111
NCBI-ProteinID:
NP_001164014
OMIM:
614939
HGNC:
28763
Ensembl:
ENSG00000247077
Pharos:
Q96HS1
(Tbio)
UniProt:
Q96HS1
Structure
PDB
PDBj
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All DBs
Position
12:132710842..132722734
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AA seq
289 aa
AA seq
DB search
MAFRQALQLAACGLAGGSAAVLFSAVAVGKPRAGGDAEPRPAEPPAWAGGARPGPGVWDP
NWDRREPLSLINVRKRNVESGEEELASKLDHYKAKATRHIFLIRHSQYHVDGSLEKDRTL
TPLGREQAELTGLRLASLGLKFNKIVHSSMTRAIETTDIISRHLPGVCKVSTDLLREGAP
IEPDPPVSHWKPEAVQYYEDGARIEAAFRNYIHRADARQEEDSYEIFICHANVIRYIVCR
ALQFPPEGWLRLSLNNGSITHLVIRPNGRVALRTLGDTGFMPPDKITRS
NT seq
870 nt
NT seq
+upstream
nt +downstream
nt
atggcgttccggcaggcgctgcagctggcggcctgcgggctggccgggggctcggccgcc
gtgctcttctcggccgtggcggtagggaagccgcgcgcaggcggggacgcggagccacgc
ccggctgagccgccggcctgggcggggggcgcgcggccgggccccggtgtctgggacccc
aactgggacaggcgagaaccactgtctctgatcaacgtgcggaagaggaacgtggaatct
ggggaagaagagctggcgtccaagctggaccactacaaagccaaggccacgcggcacatc
ttcctcatcaggcattcccagtaccacgtggatggctccctggagaaggaccgcactctg
accccgctgggtcgggagcaggctgaactcactgggctccgcctggcaagcttggggttg
aagtttaataaaatcgtccattcgtctatgacgcgcgccatagagaccaccgatatcatc
agccggcacctgccaggcgtctgcaaagtcagcacagatctgctgcgggaaggcgccccc
atcgagccagacccgcccgtgtctcattggaagccggaagctgtgcagtattacgaagac
ggagcccggatcgaggccgccttccggaactacatccaccgcgcagatgccaggcaggag
gaggacagttacgagatcttcatctgtcacgccaacgtcatccgctacatcgtgtgcaga
gcactgcagtttcctcctgaaggctggctccggctctccctcaataatggcagcatcacc
cacctggtgatccgacccaacggccgagttgcgctcaggaccctcggggacacggggttc
atgcctcccgacaagatcactcgatcctga
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