Homo sapiens (human): 196
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Entry
196 CDS
T01001
Symbol
AHR, RP85, bHLHe76
Name
(RefSeq) aryl hydrocarbon receptor
KO
K09093
aryl hydrocarbon receptor
Organism
hsa
Homo sapiens (human)
Pathway
hsa04659
Th17 cell differentiation
hsa04934
Cushing syndrome
hsa05207
Chemical carcinogenesis - receptor activation
hsa05208
Chemical carcinogenesis - reactive oxygen species
Network
nt06227
Nuclear receptor signaling (cancer)
nt06360
Cushing syndrome
Element
N00315
Mutation-inactivated AIP to AhR-mediated transcription
N00317
AhR signaling pathway
N01365
TCDD to Ahr signaling pathway
N01366
BaP to Ahr signaling pathway
N01367
PCB to Ahr signaling pathway
N01368
HCB to Ahr signaling pathway
Disease
H00527
Retinitis pigmentosa
Drug target
Tapinarof:
D11365
<JP/US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
196 (AHR)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
196 (AHR)
05208 Chemical carcinogenesis - reactive oxygen species
196 (AHR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
196 (AHR)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
196 (AHR)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
196 (AHR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PAS_3
PAS
PAS_11
HLH
PAS_4
PAS_9
Motif
Other DBs
NCBI-GeneID:
196
NCBI-ProteinID:
NP_001612
OMIM:
600253
HGNC:
348
Ensembl:
ENSG00000106546
UniProt:
P35869
Structure
PDB
LinkDB
All DBs
Position
7:17298652..17346147
Genome browser
AA seq
848 aa
AA seq
DB search
MNSSSANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDV
INKLDKLSVLRLSVSYLRAKSFFDVALKSSPTERNGGQDNCRAANFREGLNLQEGEFLLQ
ALNGFVLVVTTDALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNP
SQCTESGQGIEEATGLPQTVVCYNPDQIPPENSPLMERCFICRLRCLLDNSSGFLAMNFQ
GKLKYLHGQKKKGKDGSILPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGC
DAKGRIVLGYTEAELCTRGSGYQFIHAADMLYCAESHIRMIKTGESGMIVFRLLTKNNRW
TWVQSNARLLYKNGRPDYIIVTQRPLTDEEGTEHLRKRNTKLPFMFTTGEAVLYEATNPF
PAIMDPLPLRTKNGTSGKDSATTSTLSKDSLNPSSLLAAMMQQDESIYLYPASSTSSTAP
FENNFFNESMNECRNWQDNTAPMGNDTILKHEQIDQPQDVNSFAGGHPGLFQDSKNSDLY
SIMKNLGIDFEDIRHMQNEKFFRNDFSGEVDFRDIDLTDEILTYVQDSLSKSPFIPSDYQ
QQQSLALNSSCMVQEHLHLEQQQQHHQKQVVVEPQQQLCQKMKHMQVNGMFENWNSNQFV
PFNCPQQDPQQYNVFTDLHGISQEFPYKSEMDSMPYTQNFISCNQPVLPQHSKCTELDYP
MGSFEPSPYPTTSSLEDFVTCLQLPENQKHGLNPQSAIITPQTCYAGAVSMYQCQPEPQH
THVGQMQYNPVLPGQQAFLNKFQNGVLNETYPAELNNINNTQTTTHLQPLHHPSEARPFP
DLTSSGFL
NT seq
2547 nt
NT seq
+upstream
nt +downstream
nt
atgaacagcagcagcgccaacatcacctacgccagtcgcaagcggcggaagccggtgcag
aaaacagtaaagccaatcccagctgaaggaatcaagtcaaatccttccaagcggcataga
gaccgacttaatacagagttggaccgtttggctagcctgctgcctttcccacaagatgtt
attaataagttggacaaactttcagttcttaggctcagcgtcagttacctgagagccaag
agcttctttgatgttgcattaaaatcctcccctactgaaagaaacggaggccaggataac
tgtagagcagcaaatttcagagaaggcctgaacttacaagaaggagaattcttattacag
gctctgaatggctttgtattagttgtcactacagatgctttggtcttttatgcttcttct
actatacaagattatctagggtttcagcagtctgatgtcatacatcagagtgtatatgaa
cttatccataccgaagaccgagctgaatttcagcgtcagctacactgggcattaaatcct
tctcagtgtacagagtctggacaaggaattgaagaagccactggtctcccccagacagta
gtctgttataacccagaccagattcctccagaaaactctcctttaatggagaggtgcttc
atatgtcgtctaaggtgtctgctggataattcatctggttttctggcaatgaatttccaa
gggaagttaaagtatcttcatggacagaaaaagaaagggaaagatggatcaatacttcca
cctcagttggctttgtttgcgatagctactccacttcagccaccatccatacttgaaatc
cggaccaaaaattttatctttagaaccaaacacaaactagacttcacacctattggttgt
gatgccaaaggaagaattgttttaggatatactgaagcagagctgtgcacgagaggctca
ggttatcagtttattcatgcagctgatatgctttattgtgccgagtcccatatccgaatg
attaagactggagaaagtggcatgatagttttccggcttcttacaaaaaacaaccgatgg
acttgggtccagtctaatgcacgcctgctttataaaaatggaagaccagattatatcatt
gtaactcagagaccactaacagatgaggaaggaacagagcatttacgaaaacgaaatacg
aagttgccttttatgtttaccactggagaagctgtgttgtatgaggcaaccaaccctttt
cctgccataatggatcccttaccactaaggactaaaaatggcactagtggaaaagactct
gctaccacatccactctaagcaaggactctctcaatcctagttccctcctggctgccatg
atgcaacaagatgagtctatttatctctatcctgcttcaagtacttcaagtactgcacct
tttgaaaacaactttttcaacgaatctatgaatgaatgcagaaattggcaagataatact
gcaccgatgggaaatgatactatcctgaaacatgagcaaattgaccagcctcaggatgtg
aactcatttgctggaggtcacccagggctctttcaagatagtaaaaacagtgacttgtac
agcataatgaaaaacctaggcattgattttgaagacatcagacacatgcagaatgaaaaa
tttttcagaaatgatttttctggtgaggttgacttcagagacattgacttaacggatgaa
atcctgacgtatgtccaagattctttaagtaagtctcccttcataccttcagattatcaa
cagcaacagtccttggctctgaactcaagctgtatggtacaggaacacctacatctagaa
cagcaacagcaacatcaccaaaagcaagtagtagtggagccacagcaacagctgtgtcag
aagatgaagcacatgcaagttaatggcatgtttgaaaattggaactctaaccaattcgtg
cctttcaattgtccacagcaagacccacaacaatataatgtctttacagacttacatggg
atcagtcaagagttcccctacaaatctgaaatggattctatgccttatacacagaacttt
atttcctgtaatcagcctgtattaccacaacattccaaatgtacagagctggactaccct
atggggagttttgaaccatccccataccccactacttctagtttagaagattttgtcact
tgtttacaacttcctgaaaaccaaaagcatggattaaatccacagtcagccataataact
cctcagacatgttatgctggggccgtgtcgatgtatcagtgccagccagaacctcagcac
acccacgtgggtcagatgcagtacaatccagtactgccaggccaacaggcatttttaaac
aagtttcagaatggagttttaaatgaaacatatccagctgaattaaataacataaataac
actcagactaccacacatcttcagccacttcatcatccgtcagaagccagaccttttcct
gatttgacatccagtggattcctgtaa
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