Entry |
|
Symbol |
ABCD4, ABC41, EST352188, MAHCJ, P70R, P79R, PMP69, PXMP1L
|
Name |
(RefSeq) ATP binding cassette subfamily D member 4
|
KO |
K05678 | ATP-binding cassette, subfamily D (ALD), member 4 [EC:7.6.2.8] |
|
Organism |
|
Pathway |
hsa04977 | Vitamin digestion and absorption |
hsa04980 | Cobalamin transport and metabolism |
|
Network |
nt06538 Cobalamin transport and metabolism |
Element |
N01807 | Transfer of cobalamin to the portal blood |
|
Disease |
H02221 | Methylmalonic aciduria and homocystinuria |
|
Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
5826 (ABCD4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
5826 (ABCD4)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
5826 (ABCD4)
04980 Cobalamin transport and metabolism
5826 (ABCD4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:hsa02000]
5826 (ABCD4)
Enzymes [BR:hsa01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.8 ABC-type vitamin B12 transporter
5826 (ABCD4)
Transporters [BR:hsa02000]
ABC transporters, eukaryotic type
ABCD (ALD) subfamily
ABCD4 subgroup
5826 (ABCD4)
|
SSDB |
|
Motif |
|
Other DBs |
|
Structure |
|
LinkDB |
|
Position |
14:complement(74285269..74302934)
|
AA seq |
606 aa
MAVAGPAPGAGARPRLDLQFLQRFLQILKVLFPSWSSQNALMFLTLLCLTLLEQFVIYQV
GLIPSQYYGVLGNKDLEGFKTLTFLAVMLIVLNSTLKSFDQFTCNLLYVSWRKDLTEHLH
RLYFRGRAYYTLNVLRDDIDNPDQRISQDVERFCRQLSSMASKLIISPFTLVYYTYQCFQ
STGWLGPVSIFGYFILGTVVNKTLMGPIVMKLVHQEKLEGDFRFKHMQIRVNAEPAAFYR
AGHVEHMRTDRRLQRLLQTQRELMSKELWLYIGINTFDYLGSILSYVVIAIPIFSGVYGD
LSPAELSTLVSKNAFVCIYLISCFTQLIDLSTTLSDVAGYTHRIGQLRETLLDMSLKSQD
CEILGESEWGLDTPPGWPAAEPADTAFLLERVSISAPSSDKPLIKDLSLKISEGQSLLIT
GNTGTGKTSLLRVLGGLWTSTRGSVQMLTDFGPHGVLFLPQKPFFTDGTLREQVIYPLKE
VYPDSGSADDERILRFLELAGLSNLVARTEGLDQQVDWNWYDVLSPGEMQRLSFARLFYL
QPKYAVLDEATSALTEEVESELYRIGQQLGMTFISVGHRQSLEKFHSLVLKLCGGGRWEL
MRIKVE |
NT seq |
1821 nt +upstreamnt +downstreamnt
atggcggtcgcggggcccgcgcccggagctggcgccaggcccaggttagatctgcaattt
ctccagcggttcctgcagatactgaaggttttgtttccttcttggtcatcacaaaatgcc
ttgatgttcctgacccttttgtgcctgaccctactggagcaatttgtgatctaccaggtt
ggcttgatccccagtcagtactatggggtcctgggaaacaaagacttggaagggtttaag
actctgacattcctggctgtcatgctcattgttctgaactccacgctgaagagctttgat
cagttcacctgcaacctgctgtatgtgagctggaggaaggacctcactgagcaccttcac
cgcctctacttccggggccgtgcgtactacaccctcaacgtgctgcgggatgacatcgat
aacccggaccagcgcatcagccaggacgtggagcgattctgccggcagctcagcagcatg
gccagcaagctcatcatctccccgttcaccctcgtctactacacttaccagtgcttccaa
agcacaggctggctcgggcctgtgagcatcttcgggtatttcatcctggggaccgtggtg
aacaaaactttgatgggccccattgtgatgaagctggtgcatcaggagaagctggaggga
gattttaggttcaagcacatgcagattcgggtgaatgcggagcctgctgctttctacaga
gctgggcatgtggagcacatgaggacagaccgcaggctgcagagactccttcagacccag
agggagctgatgtccaaggagctctggctgtacatcggcatcaacacctttgactatctg
ggcagcatcctgagttacgttgtcatcgcaatccccattttcagcggggtctatggagac
ctgagtcccgcagagcttagcaccctggtcagcaagaatgcctttgtgtgcatctacctc
atcagctgcttcacccagctcatcgacctgtccacgacgctctcagatgtggctggctac
acgcacagaattgggcagcttcgggagacgcttctggacatgtccctgaagtcacaggac
tgcgagatcctgggcgagagcgagtggggcttggacacacccccagggtggccagcggca
gagccagcagacacagcatttctccttgagcgggtctccatctctgccccctcctctgac
aaacccctaatcaaggatctgagcctaaagatctccgagggacagagcctgctcatcaca
ggcaacacgggcactggcaagacctccttgctccgggttctgggtggcctctggacgagt
acacggggctcagtgcagatgctgacggactttgggccccatggggtgctattcctgcca
caaaagccattcttcactgacgggacccttcgggagcaggtgatatatcccctgaaggag
gtctaccccgactcaggttctgccgatgatgagaggatcttgaggttcttggaattggca
ggcctgtccaacttggtggcaaggacagagggcctggaccagcaggtggactggaactgg
tatgatgttctgtccccgggggagatgcaacggctctcctttgcccgactcttctacctg
cagccgaagtacgcagtgcttgatgaagccaccagtgccctgacagaggaagtggagagc
gagctctatcgcatcggccagcagctggggatgacgttcatcagtgtgggacatcggcag
agccttgagaagtttcattccttggttctgaaactctgtggaggaggaagatgggagctg
atgagaatcaaagtggaatga |