Homo sapiens (human): 219931 Help Entry 219931            CDS       T01001                                  Symbol TPCN2, SHEP10, TPC2 Name (RefSeq) two pore segment channel 2   KO K14077   two pore calcium channel protein 2 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04972   Pancreatic secretion Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     219931 (TPCN2)  09150 Organismal Systems   09154 Digestive system    04972 Pancreatic secretion     219931 (TPCN2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     219931 (TPCN2) Ion channels [BR:hsa04040]  Voltage-gated cation channels   Calcium channel, two-pore (TPC)    219931 (TPCN2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Ion_trans Motif Other DBs NCBI-GeneID:  219931 NCBI-ProteinID:  NP_620714 OMIM:  612163 HGNC:  20820 Ensembl:  ENSG00000162341 UniProt:  Q8NHX9 Q59G56 Structure PDB LinkDB All DBs Position 11:69048932..69090597 Genome browser AA seq 752 aa AA seqDB search MAEPQAESEPLLGGARGGGGDWPAGLTTYRSIQVGPGAAARWDLCIDQAVVFIEDAIQYR SINHRVDASSMWLYRRYYSNVCQRTLSFTIFLILFLAFIETPSSLTSTADVRYRAAPWEP PCGLTESVEVLCLLVFAADLSVKGYLFGWAHFQKNLWLLGYLVVLVVSLVDWTVSLSLVC HEPLRIRRLLRPFFLLQNSSMMKKTLKCIRWSLPEMASVGLLLAIHLCLFTMFGMLLFAG GKQDDGQDRERLTYFQNLPESLTSLLVLLTTANNPDVMIPAYSKNRAYAIFFIVFTVIGS LFLMNLLTAIIYSQFRGYLMKSLQTSLFRRRLGTRAAFEVLSSMVGEGGAFPQAVGVKPQ NLLQVLQKVQLDSSHKQAMMEKVRSYGSVLLSAEEFQKLFNELDRSVVKEHPPRPEYQSP FLQSAQFLFGHYYFDYLGNLIALANLVSICVFLVLDADVLPAERDDFILGILNCVFIVYY LLEMLLKVFALGLRGYLSYPSNVFDGLLTVVLLVLEISTLAVYRLPHPGWRPEMVGLLSL WDMTRMLNMLIVFRFLRIIPSMKLMAVVASTVLGLVQNMRAFGGILVVVYYVFAIIGINL FRGVIVALPGNSSLAPANGSAPCGSFEQLEYWANNFDDFAAALVTLWNLMVVNNWQVFLD AYRRYSGPWSKIYFVLWWLVSSVIWVNLFLALILENFLHKWDPRSHLQPLAGTPEATYQM TVELLFRDILEEPGEDELTERLSQHPHLWLCR NT seq 2259 nt NT seq  +upstreamnt  +downstreamnt atggcggaaccccaggcggagtcggagcccctgctgggcggggcccgcggcggtggcggc gactggccggcggggctgaccacttaccgcagcatccaagtcggccctggtgccgcggcc aggtgggacctctgcattgatcaggctgtggtcttcatcgaagatgctattcagtaccgc tccatcaaccaccgggtggatgccagctcgatgtggctttaccgacggtattactcgaac gtatgccaacggactttgagcttcaccatcttcttgatcctgtttttggcttttatcgag accccatcctcactcaccagcacggcggacgtgcgctaccgcgctgctccctgggagccg ccctgcggcctgaccgagagtgtcgaggtgctctgcctgctggtctttgcggccgacctc tctgtgaagggttacctgttcgggtgggcccatttccagaaaaacctttggctgctgggc tacctcgtggtgctggtggtgtctctggtggactggaccgtgtccctgagtctcgtgtgt catgagcccctgcggatccgccggcttctccgtcccttcttcctgctgcagaactcctct atgatgaagaagaccttgaaatgcatccgctggtcgctgccggaaatggccagcgtcggg ctgctgctggccatccacctgtgcctcttcaccatgttcggaatgctgctgttcgctggt gggaagcaggatgatgggcaggacagggagaggctgacctacttccagaacctgcctgag tctctgacttccctcctggtgctgctgaccacggccaacaaccccgatgtgatgattcct gcgtattccaagaaccgggcctatgccatcttcttcatagtcttcactgtgataggaagc ctgtttctgatgaacctgctgacagccatcatctacagtcagttccggggctacctgatg aaatctctccagacctcgctgtttcggaggcggctgggaacccgggctgcctttgaagtc ctatcctccatggtgggggagggaggagccttccctcaggcagttggggtgaagccccag aacttgctgcaggtgcttcagaaggtccagctggacagctcccacaaacaggccatgatg gagaaggtgcgttcctatggcagtgttctgctctcagctgaggagtttcagaagctcttc aacgagcttgacagaagtgtggttaaagagcacccgccgaggcccgagtaccagtctccg tttctgcagagcgcccagttcctcttcggccactactactttgactacctggggaacctc atcgccctggcaaacctggtgtccatttgcgtgttcctggtgctggatgcagatgtgctg cctgctgagcgtgatgacttcatcctggggattctcaactgcgtcttcattgtgtactac ctgttggagatgctgctcaaggtctttgccctgggcctgcgagggtacctgtcctacccc agcaacgtgtttgacgggctcctcaccgttgtcctgctggttttggagatctcaactctg gctgtgtaccgattgccacacccaggctggaggccggagatggtgggcctgctgtcgctg tgggacatgacccgcatgctgaacatgctcatcgtgttccgcttcctgcgtatcatcccc agcatgaagctgatggccgtggtggccagtaccgtcctgggcctggtgcagaacatgcgt gcgtttggcgggatcctggtggtggtctactacgtatttgccatcattgggatcaacttg tttagaggcgtcattgtggctcttcctggaaacagcagcctggcccctgccaatggctcg gcgccctgtgggagcttcgagcagctggagtactgggccaacaacttcgatgactttgcg gctgccctggtcactctgtggaacttgatggtggtgaacaactggcaggtgtttctggat gcatatcggcgctactcaggcccgtggtccaagatctattttgtattgtggtggctggtg tcgtctgtcatctgggtcaacctgtttctggccctgattctggagaacttccttcacaag tgggacccccgcagccacctgcagccccttgctgggaccccagaggccacctaccagatg actgtggagctcctgttcagggatattctggaggagcccggggaggatgagctcacagag aggctgagccagcacccgcacctgtggctgtgcaggtga

Homo sapiens (human): 53373 Help Entry 53373             CDS       T01001                                  Symbol TPCN1, TPC1 Name (RefSeq) two pore segment channel 1   KO K16896   two pore calcium channel protein 1 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     53373 (TPCN1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hsa04040]     53373 (TPCN1) Ion channels [BR:hsa04040]  Voltage-gated cation channels   Calcium channel, two-pore (TPC)    53373 (TPCN1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Ion_trans Pilin_N Death Motif Other DBs NCBI-GeneID:  53373 NCBI-ProteinID:  NP_060371 OMIM:  609666 HGNC:  18182 Ensembl:  ENSG00000186815 UniProt:  Q9ULQ1 B3KSG7 LinkDB All DBs Position 12:113221464..113298585 Genome browser AA seq 816 aa AA seqDB search MAVSLDDDVPLILTLDEGGSAPLAPSNGLGQEELPSKNGGSYAIHDSQAPSLSSGGESSP SSPAHNWEMNYQEAAIYLQEGENNDKFFTHPKDAKALAAYLFAHNHLFYLMELATALLLL LLSLCEAPAVPALRLGIYVHATLELFALMVVVFELCMKLRWLGLHTFIRHKRTMVKTSVL VVQFVEAIVVLVRQMSHVRVTRALRCIFLVDCRYCGGVRRNLRQIFQSLPPFMDILLLLL FFMIIFAILGFYLFSPNPSDPYFSTLENSIVSLFVLLTTANFPDVMMPSYSRNPWSCVFF IVYLSIELYFIMNLLLAVVFDTFNDIEKRKFKSLLLHKRTAIQHAYRLLISQRRPAGISY RQFEGLMRFYKPRMSARERYLTFKALNQNNTPLLSLKDFYDIYEVAALKWKAKKNREHWF DELPRTALLIFKGINILVKSKAFQYFMYLVVAVNGVWILVETFMLKGGNFFSKHVPWSYL VFLTIYGVELFLKVAGLGPVEYLSSGWNLFDFSVTVFAFLGLLALALNMEPFYFIVVLRP LQLLRLFKLKERYRNVLDTMFELLPRMASLGLTLLIFYYSFAIVGMEFFCGIVFPNCCNT STVADAYRWRNHTVGNRTVVEEGYYYLNNFDNILNSFVTLFELTVVNNWYIIMEGVTSQT SHWSRLYFMTFYIVTMVVMTIIVAFILEAFVFRMNYSRKNQDSEVDGGITLEKEISKEEL VAVLELYREARGASSDVTRLLETLSQMERYQQHSMVFLGRRSRTKSDLSLKMYQEEIQEW YEEHAREQEQQRQLSSSAAPAAQQPPGSRQRSQTVT NT seq 2451 nt NT seq  +upstreamnt  +downstreamnt atggctgtgagtttggatgacgacgtgccgctcatcctgaccttggatgagggtggcagt gccccactggctccctccaacggcctgggccaagaagagctacctagcaaaaatggcggc agctatgccatccacgactcccaggcccccagtctcagctctgggggtgagagttccccc tccagccccgcacacaactgggagatgaattaccaagaggcagcaatctacctccaggaa ggcgagaacaacgacaagttcttcacccaccccaaggatgccaaggcgctggcggcctac ctctttgcacacaatcacctcttctacctgatggagctggccacggccctgctgctgctg ctgctctccctgtgcgaggcccccgccgtccccgcactccggcttggcatctatgtccac gccaccctggagctgtttgccctgatggtggtagtgtttgaactctgcatgaagttacgc tggctgggcctccacaccttcatccggcacaagcggaccatggtcaagacctcggtgctg gtggtgcagtttgtcgaggccatcgtggtgttggtacggcagatgtcccatgtgcgggtg acccgagcactgcgctgcattttcctggtggactgtcggtattgcggtggcgtccggcgc aacctgcggcagatcttccagtccctgccgcccttcatggacatcctcctgctgctgctg ttcttcatgatcatctttgccatcctcggtttctacttgttctcccctaacccttcagac ccctacttcagcaccctggagaacagcatcgtcagtctgtttgtccttctgaccacagcc aatttcccagatgtgatgatgccctcctactcccggaacccctggtcctgcgtcttcttc atcgtgtacctctccatcgagctgtatttcatcatgaacctgcttctggctgtggtgttc gacaccttcaatgacattgagaaacgcaagttcaagtctttgctactgcacaagcgaacc gctatccagcatgcctaccgcctgctcatcagccagaggaggcctgccggcatctcctac aggcagtttgaaggcctcatgcgcttctacaagccccggatgagtgccagggagcgctat cttaccttcaaggccctgaatcagaacaacacacccctgctcagcctaaaggacttttac gatatctacgaagttgctgctttgaagtggaaggccaagaaaaacagagagcactggttt gatgagcttcccaggacggcgctcctcatcttcaaaggtattaatatccttgtgaagtcc aaggccttccagtatttcatgtacttggtggtggcagtcaacggggtctggatcctcgtg gagacatttatgctgaaaggtgggaacttcttctccaagcacgtgccctggagttacctc gtctttctaactatctatggggtggagctgttcctgaaggttgccggcctgggccctgtg gagtacttgtcttccggatggaacttgtttgacttctccgtgacagtgttcgccttcctg ggactgctggcgctggccctcaacatggagcccttctatttcatcgtggtcctgcgcccc ctccagctgctgaggttgtttaagttgaaggagcgctaccgcaacgtgctggacaccatg ttcgagctgctgccccggatggccagcctgggcctcaccctgctcatcttttactactcc ttcgccatcgtgggcatggagttcttctgcgggatcgtcttccccaactgctgcaacacg agtacagtggcagatgcctaccgctggcgcaaccacaccgtgggcaacaggaccgtggtg gaggaaggctactattatctcaataattttgacaacatcctcaacagctttgtgaccctg tttgagctcacagttgtcaacaactggtacatcatcatggaaggcgtcacctctcagacc tcccactggagccgcctctacttcatgaccttttacattgtgaccatggtggtgatgacg atcattgtcgcctttatcctcgaggccttcgtcttccgaatgaactacagccgcaagaac caggactcggaagttgatggtggcatcacccttgagaaggaaatctccaaagaagagctg gttgccgtcctggagctctaccgggaggcacggggggcctcctcggatgtcaccaggctg ctggagaccctctcccagatggagagataccagcaacattccatggtgtttctgggacgg cgatcaaggaccaagagcgacctgagcctgaagatgtaccaggaggagatccaggagtgg tatgaggagcatgccagggagcaagagcagcagcgacaactcagcagcagtgcagccccc gccgcccagcagcccccaggcagccgccagcgctcccagaccgttacctag

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