KEGG   Homo sapiens (human): 2288
Entry
2288              CDS       T01001                                 
Symbol
FKBP4, FKBP51, FKBP52, FKBP59, HBI, Hsp56, PPIase, p52
Name
(RefSeq) FKBP prolyl isomerase 4
  KO
K09571  FK506-binding protein 4/5 [EC:5.2.1.8]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04915  Estrogen signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    2288 (FKBP4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    2288 (FKBP4)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.2  cis-trans-Isomerases
   5.2.1  cis-trans Isomerases (only sub-subclass identified to date)
    5.2.1.8  peptidylprolyl isomerase
     2288 (FKBP4)
Chaperones and folding catalysts [BR:hsa03110]
 Protein folding catalysts
  Peptidyl prolyl isomerase
   FKBP
    2288 (FKBP4)
SSDB
Motif
Pfam: FKBP_C TPR_1 TPR_2 TPR_8 TPR_12 TPR_11 TPR_16 FKBP_N_2 TPR_6 TPR_14 TPR_19 TPR_7 TPR_9 PknG_TPR TPR_17 DUF3856
Other DBs
NCBI-GeneID: 2288
NCBI-ProteinID: NP_002005
OMIM: 600611
HGNC: 3720
Ensembl: ENSG00000004478
Pharos: Q02790(Tchem)
UniProt: Q02790
Structure
LinkDB
Position
12:2794970..2805423
AA seq 459 aa
MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW
LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP
KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD
KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN
AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL
EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG
EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE
EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA
NT seq 1380 nt   +upstreamnt  +downstreamnt
atgacagccgaggagatgaaggcgaccgagagcggggcgcagtcggcgccgctgcccatg
gagggagtggacatcagccccaaacaggacgaaggcgtgctgaaggtcatcaagagagag
ggcacaggtacagagatgcccatgattggggaccgagtctttgtccactacactggctgg
ctattagatggcacaaagtttgactccagtctggatcgcaaggacaaattctcctttgac
ctgggaaaaggggaggtcatcaaggcttgggacattgccatagccaccatgaaggtgggg
gaggtgtgccacatcacctgcaaaccagaatatgcctacggttcagcaggcagtcctcca
aagattccccccaatgccacgcttgtatttgaggtggagttgtttgagtttaagggagaa
gatctgacggaagaggaagatggcggaatcattcgcagaatacagactcgcggtgaaggc
tatgctaagcccaatgagggtgctatcgtggaggttgcactggaagggtactacaaggac
aagctctttgaccagcgggagctccgctttgagattggcgagggggagaacctggatctg
ccttatggtctggagagggccattcagcgcatggagaaaggagaacattccatcgtgtac
ctcaagcccagctatgcttttggcagtgttgggaaggaaaagttccaaatcccaccaaat
gctgagctgaaatatgaattacacctcaagagttttgaaaaggccaaggagtcttgggag
atgaattcagaagagaagctggaacagagcaccatagtgaaagagcggggcactgtgtac
ttcaaggaaggtaaatacaagcaagctttactacagtataagaagatcgtgtcttggctg
gaatatgagtctagtttttccaatgaggaagcacagaaagcacaggcccttcgactggcc
tctcacctcaacctggccatgtgtcatctgaaactacaggccttctctgctgccattgaa
agctgtaacaaggccctagaactggacagcaacaacgagaagggcctcttccgccgggga
gaggcccacctggccgtgaatgactttgaactggcacgggctgatttccagaaggtcctg
cagctctaccccaacaacaaagccgccaagacccagctggctgtgtgccagcagcggatc
cgaaggcagcttgcccgggagaagaagctctatgccaatatgtttgagaggctggctgag
gaggagaacaaggccaaggcagaggcttcctcaggagaccatcccactgacacagagatg
aaggaggagcagaagagcaacacggcagggagccagtctcaggtggagacagaagcatag

KEGG   Homo sapiens (human): 2289
Entry
2289              CDS       T01001                                 
Symbol
FKBP5, AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10
Name
(RefSeq) FKBP prolyl isomerase 5
  KO
K09571  FK506-binding protein 4/5 [EC:5.2.1.8]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04915  Estrogen signaling pathway
Disease
H01646  Major depressive disorder
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    2289 (FKBP5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    2289 (FKBP5)
Enzymes [BR:hsa01000]
 5. Isomerases
  5.2  cis-trans-Isomerases
   5.2.1  cis-trans Isomerases (only sub-subclass identified to date)
    5.2.1.8  peptidylprolyl isomerase
     2289 (FKBP5)
Chaperones and folding catalysts [BR:hsa03110]
 Protein folding catalysts
  Peptidyl prolyl isomerase
   FKBP
    2289 (FKBP5)
SSDB
Motif
Pfam: FKBP_C TPR_1 TPR_2 TPR_8 TPR_6 TPR_19 TPR_7 TPR_12 TPR_9 TPR_11 Fis1_TPR_C ANAPC3 PknG_TPR NatA_aux_su
Other DBs
NCBI-GeneID: 2289
NCBI-ProteinID: NP_001139247
OMIM: 602623
HGNC: 3721
Ensembl: ENSG00000096060
Pharos: Q13451(Tchem)
UniProt: Q13451
Structure
LinkDB
Position
6:complement(35573590..35728583)
AA seq 457 aa
MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE
LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM
EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA
QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD
AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV
NT seq 1374 nt   +upstreamnt  +downstreamnt
atgactactgatgaaggtgccaagaacaatgaagaaagccccacagccactgttgctgag
cagggagaggatattacctccaaaaaagacaggggagtattaaagattgtcaaaagagtg
gggaatggtgaggaaacgccgatgattggagacaaagtttatgtccattacaaaggaaaa
ttgtcaaatggaaagaagtttgattccagtcatgatagaaatgaaccatttgtctttagt
cttggcaaaggccaagtcatcaaggcatgggacattggggtggctaccatgaagaaagga
gagatatgccatttactgtgcaaaccagaatatgcatatggctcggctggcagtctccct
aaaattccctcgaatgcaactctcttttttgagattgagctccttgatttcaaaggagag
gatttatttgaagatggaggcattatccggagaaccaaacggaaaggagagggatattca
aatccaaacgaaggagcaacagtagaaatccacctggaaggccgctgtggtggaaggatg
tttgactgcagagatgtggcattcactgtgggcgaaggagaagaccacgacattccaatt
ggaattgacaaagctctggagaaaatgcagcgggaagaacaatgtattttatatcttgga
ccaagatatggttttggagaggcagggaagcctaaatttggcattgaacctaatgctgag
cttatatatgaagttacacttaagagcttcgaaaaggccaaagaatcctgggagatggat
accaaagaaaaattggagcaggctgccattgtcaaagagaagggaaccgtatacttcaag
ggaggcaaatacatgcaggcggtgattcagtatgggaagatagtgtcctggttagagatg
gaatatggtttatcagaaaaggaatcgaaagcttctgaatcatttctccttgctgccttt
ctgaacctggccatgtgctacctgaagcttagagaatacaccaaagctgttgaatgctgt
gacaaggcccttggactggacagtgccaatgagaaaggcttgtataggaggggtgaagcc
cagctgctcatgaacgagtttgagtcagccaagggtgactttgagaaagtgctggaagta
aacccccagaataaggctgcaagactgcagatctccatgtgccagaaaaaggccaaggag
cacaacgagcgggaccgcaggatatacgccaacatgttcaagaagtttgcagagcaggat
gccaaggaagaggccaataaagcaatgggcaagaagacttcagaaggggtcactaatgaa
aaaggaacagacagtcaagcaatggaagaagagaaacctgagggccacgtatga

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