KEGG   Homo sapiens (human): 22925
Entry
22925             CDS       T01001                                 
Symbol
PLA2R1, CLEC13C, PLA2-R, PLA2G1R, PLA2IR, PLA2R
Name
(RefSeq) phospholipase A2 receptor 1
  KO
K06560  mannose receptor, C type
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa05152  Tuberculosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    22925 (PLA2R1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    22925 (PLA2R1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    22925 (PLA2R1)
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors [BR:hsa04054]
    22925 (PLA2R1)
   04090 CD molecules [BR:hsa04090]
    22925 (PLA2R1)
   04091 Lectins [BR:hsa04091]
    22925 (PLA2R1)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Phagocytosis
   C-lectin receptors
    22925 (PLA2R1)
Pattern recognition receptors [BR:hsa04054]
 Membrane-bound pattern recognition receptors
  C-type lectin receptors
   22925 (PLA2R1)
CD molecules [BR:hsa04090]
 Proteins
  22925 (PLA2R1)
Lectins [BR:hsa04091]
 C-Type lectins
  Group 6: Mannose receptor family
   22925 (PLA2R1)
SSDB
Motif
Pfam: Lectin_C fn2 UL45 Xlink Chordopox_A33R Ricin_B_lectin
Other DBs
NCBI-GeneID: 22925
NCBI-ProteinID: NP_031392
OMIM: 604939
HGNC: 9042
Ensembl: ENSG00000153246
UniProt: Q13018
Structure
LinkDB
Position
2:complement(159923933..160062615)
AA seq 1463 aa
MLLSPSLLLLLLLGAPRGCAEGVAAALTPERLLEWQDKGIFVIQSESLKKCIQAGKSVLT
LENCKQANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQPLSLYECDSTLVSLRWRCNRK
MITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLHKDLHTIKGNTHGMPCMF
PFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPTSAEVGCDTIWEKDLNSH
ICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTVEVWMGLNQLDEH
AGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNH
IDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLA
EVEFLVTLLGDENASETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVS
AEQSEGHWKVKNCEERLFYICKKAGHVLSDAESGCQEGWERHGGFCYKIDTVLRSFDQAS
SGYYCPPALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEP
VQYTHWNTHQPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWP
FHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNE
LLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFGEDARNCAVYKAN
KTLLPLHCGSKREWICKIPRDVKPKIPFWYQYDVPWLFYQDAEYLFHTFASEWLNFEFVC
SWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWD
TGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGTCPK
GWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTS
VWIGLQNDDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTG
KWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIK
TCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKD
EESSLLGDCVFADSNGRWHSTACESFLQGAICHVPPETRQSEHPELCSETSIPWIKFKSN
CYSFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENAFLLEELFAFGSSVQMVWLNAQFD
GNNETIKWFDGTPTDQSNWGIRKPDTDYFKPHHCVALRIPEGLWQLSPCQEKKGFICKME
ADIHTAEALPEKGPSHSIIPLAVVLTLIVIVAICTLSFCIYKHNGGFFRRLAGFRNPYYP
ATNFSTVYLEENILISDLEKSDQ
NT seq 4392 nt   +upstreamnt  +downstreamnt
atgctgctgtcgccgtcgctgctgctgctgctgctgctgggggcgccgcggggctgcgcc
gagggtgtggcggcggcgcttacccccgagcggctcctggagtggcaggataaaggaata
tttgttatccaaagtgagagtctcaagaaatgcattcaagcaggtaaatcggttctgacc
ctggagaactgcaagcaagcaaacaagcacatgctgtggaaatgggtttcaaaccatggc
ctctttaacataggaggcagtggttgcctgggcctgaatttctccgccccagagcagcca
ttaagcttatatgaatgtgactccaccctcgtttccttacggtggcgctgtaacaggaag
atgatcacaggcccgctgcagtactctgtccaggtggcgcatgacaacacagtggtggcc
tcacggaagtatattcataagtggatttcttatgggtcaggtggtggagacatttgtgaa
tatctacacaaagatttgcatacaatcaaagggaacacccacgggatgccgtgtatgttt
cccttccagtataaccatcagtggcatcatgaatgtacccgtgaaggtcgggaagatgac
ttactgtggtgtgccacgacaagccgttatgaaagagatgaaaagtggggattttgccct
gatcccacctctgcagaagtaggttgtgatactatttgggagaaggacctcaattcacac
atttgctaccagttcaacctgctttcatctctctcttggagtgaggcacattcttcatgc
cagatgcaaggaggtacgctgttaagtattacagatgaaactgaagaaaatttcataagg
gagcacatgagcagtaaaacagtggaggtgtggatgggcctcaatcagctggatgaacac
gctggctggcagtggtctgatggaacgccgctcaactatctgaattggagcccagaggta
aattttgagccatttgttgaagatcactgtggaacatttagttcatttatgccaagtgcc
tggaggagtcgggattgtgagtccaccttgccatatatatgtaaaaaatatctaaaccac
attgatcatgaaatagttgaaaaagatgcgtggaaatattatgctacccactgtgagcct
ggctggaatccctacaatcgtaattgctacaaacttcagaaagaagaaaagacctggcat
gaggctctgcgttcttgtcaggctgataacagtgcattaatagacataacctcattagca
gaggtggagtttcttgtaaccctccttggagatgaaaatgcatcagaaacatggattggt
ttgagcagcaataaaattccagtttcctttgaatggtctaatgactcttcagtcatcttt
actaattggcacacacttgagccccacatttttccaaatagaagccagctgtgtgtctca
gcagagcagtctgagggacactggaaagtcaaaaattgtgaagaaagacttttttacatt
tgtaaaaaagcaggccatgtcctctctgatgctgaatcaggatgtcaagagggatgggag
agacatggtggattctgttacaaaattgacacagtccttcgaagctttgaccaagcttcc
agcggttattactgtcctcctgcacttgtaaccattacaaacaggtttgaacaggctttt
attaccagtttgatcagtagtgtggtaaaaatgaaggacagttatttttggatagctctt
caggaccaaaatgatacgggagaatacacttggaagccagtagggcagaaacccgagccg
gtgcagtacacacactggaacacacaccagccgcgctacagtggtggctgtgttgccatg
cgaggaaggcatccacttggtcgctgggaagtgaagcactgtcggcactttaaggcaatg
tccttgtgcaagcagccagttgaaaatcaggaaaaagcagagtatgaagagagatggccc
tttcacccctgctatttggactgggagtcagagcctggtctggccagttgcttcaaggta
tttcatagtgaaaaagttctgatgaaaagaacatggagagaagctgaagcattttgcgaa
gaatttggagctcatcttgcaagctttgcccatattgaggaagagaattttgtgaatgag
ctcttacattcaaaatttaattggacagaagaaaggcagttctggattggatttaataaa
agaaacccactgaatgccggctcatgggagtggtctgatagaactcctgttgtctcttcg
tttttagacaacacttattttggagaagatgcaagaaactgtgctgtttataaggcaaac
aaaacattgctgcccttacactgtggttccaaacgtgaatggatatgcaaaatcccaaga
gatgtgaaacccaagattccgttctggtaccagtacgatgtaccctggctcttttatcag
gatgcagaatacctttttcatacctttgcctcagaatggttgaactttgagtttgtctgt
agctggctgcacagtgatcttctcacaattcattctgcacatgagcaagaattcatccac
agcaaaataaaagcgctatcaaagtatggtgcaagttggtggattggacttcaagaagaa
agagccaatgatgaatttcgctggagagatggaacaccagtgatataccagaactgggac
acaggaagagaaagaactgtgaataatcagagccagagatgtggctttatttcttctata
acaggactctggggtagtgaagagtgttcagtttctatgcctagtatctgtaagcgaaaa
aaggtttggctcatagagaaaaagaaagatacaccaaaacaacatggaacgtgtcccaaa
ggatggctatattttaactataagtgccttctgctgaatatccccaaagacccaagcagt
tggaagaactggacgcatgctcaacatttctgtgctgaagaaggggggaccctggtcgcc
attgaaagtgaggtggagcaagctttcattactatgaatctttttggccagaccaccagt
gtgtggataggtttacaaaatgatgattatgaaacatggctaaatggaaagcctgtggta
tattctaactggtctccatttgatataataaatattccaagtcacaataccactgaagtt
cagaaacacattcctctctgtgccttactctcaagtaatcctaattttcatttcactgga
aaatggtattttgaagactgtggaaaggaaggctatgggtttgtttgtgaaaaaatgcaa
gatacttctggacacggtgtaaatacatctgatatgtatccaatgcccaataccttagaa
tatggaaacagaacttacaaaataattaatgcaaatatgacttggtatgcagcaataaaa
acctgcctgatgcacaaagcacaactggtcagcatcacagaccagtatcaccagtccttc
ctcactgttgtcctcaaccggctaggatatgcccactggattggactgttcaccacagat
aatggtcttaattttgactggtctgatggcaccaaatcttctttcactttttggaaagat
gaggagtcctccctccttggtgactgcgtttttgccgacagcaacggacgctggcatagc
acagcctgcgagtcatttctgcaaggtgccatttgtcatgtgccacctgaaacaagacaa
tctgaacacccagagttgtgctcagaaacatctattccctggataaaatttaaaagtaat
tgctacagtttttctacagtcctagacagtatgagttttgaggctgctcatgaattttgc
aaaaaggaaggttctaatcttttaacaatcaaggatgaggctgaaaatgcatttctccta
gaagagctgtttgcttttggttcttctgtccagatggtttggttgaatgctcaatttgat
ggtaacaatgaaaccataaagtggtttgatggaactcccacagaccagtcaaactggggc
attcggaagccagacacagactacttcaagccccatcattgtgttgccttgaggatccct
gaaggattatggcagctatccccgtgtcaagaaaaaaaaggctttatatgtaaaatggag
gcagatattcacactgcagaggcgctgccagaaaaaggaccaagtcacagcatcattcct
cttgcggttgtactgacactgatagtcattgtggccatttgcacactttccttctgcata
tacaagcataacggtggcttcttcaggagacttgcagggtttcggaatccttactatcct
gcaaccaactttagtacagtatatttagaagaaaatattctcatttctgatcttgagaag
agtgaccaataa

KEGG   Homo sapiens (human): 4360
Entry
4360              CDS       T01001                                 
Symbol
MRC1, CD206, CLEC13D, CLEC13DL, MMR, MRC1L1, bA541I19.1, hMR
Name
(RefSeq) mannose receptor C-type 1
  KO
K06560  mannose receptor, C type
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa05152  Tuberculosis
Drug target
Technetium (99mTc) tilmanocept: D11543<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    4360 (MRC1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    4360 (MRC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    4360 (MRC1)
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors [BR:hsa04054]
    4360 (MRC1)
   04090 CD molecules [BR:hsa04090]
    4360 (MRC1)
   04091 Lectins [BR:hsa04091]
    4360 (MRC1)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Phagocytosis
   C-lectin receptors
    4360 (MRC1)
Pattern recognition receptors [BR:hsa04054]
 Membrane-bound pattern recognition receptors
  C-type lectin receptors
   4360 (MRC1)
CD molecules [BR:hsa04090]
 Proteins
  4360 (MRC1)
Lectins [BR:hsa04091]
 C-Type lectins
  Group 6: Mannose receptor family
   4360 (MRC1)
SSDB
Motif
Pfam: Lectin_C fn2 Ricin_B_lectin Xlink UL45 CDtoxinA
Other DBs
NCBI-GeneID: 4360
NCBI-ProteinID: NP_002429
OMIM: 153618
HGNC: 7228
Ensembl: ENSG00000260314
UniProt: P22897
Structure
LinkDB
Position
10:17809348..17911164
AA seq 1456 aa
MRLPLLLVFASVIPGAVLLLDTRQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRW
VSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYG
NRQEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPFKFENKWYA
DCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNKDPLTSVSYQINSKSALTW
HQARKSCQQQNAELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSPFRY
LNWLPGSPSAEPGKSCVSLNPGKNAKWENLECVQKLGYICKKGNTTLNSFVIPSESDVPT
HCPSQWWPYAGHCYKIHRDEKKIQRDALTTCRKEGGDLTSIHTIEELDFIISQLGYEPND
ELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEW
PLGYICKMKSRSQGPEIVEVEKGCRKGWKKHHFYCYMIGHTLSTFAEANQTCNNENAYLT
TIEDRYEQAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTHWNSDMPGRKPGC
VAMRTGIAGGLWDVLKCDEKAKFVCKHWAEGVTHPPKPTTTPEPKCPEDWGASSRTSLCF
KLYAKGKHEKKTWFESRDFCRALGGDLASINNKEEQQTIWRLITASGSYHKLFWLGLTYG
SPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGDPTMSWNDINCEHLNNWICQIQ
KGQTPKPEPTPAPQDNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCKRNFGDLVSIQS
ESEKKFLWKYVNRNDAQSAYFIGLLISLDKKFAWMDGSKVDYVSWATGEPNFANEDENCV
TMYSNSGFWNDINCGYPNAFICQRHNSSINATTVMPTMPSVPSGCKEGWNFYSNKCFKIF
GFMEEERKNWQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDSTFSAWTGLNDVNSEHTF
LWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSKRGYICQ
TRSDPSLTNPPATIQTDGFVKYGKSSYSLMRQKFQWHEAETYCKLHNSLIASILDPYSNA
FAWLQMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNWAADEPKLKSACVYLDLDGYWK
TAHCNESFYFLCKRSDEIPATEPPQLPGRCPESDHTAWIPFHGHCYYIESSYTRNWGQAS
LECLRMGSSLVSIESAAESSFLSYRVEPLKSKTNFWIGLFRNVEGTWLWINNSPVSFVNW
NTGDPSGERNDCVALHASSGFWSNIHCSSYKGYICKRPKIIDAKPTHELLTTKADTRKMD
PSKPSSNVAGVVIIVILLILTGAGLAAYFFYKKRRVHLPQEGAFENTLYFNSQSSPGTSD
MKDLVGNIEQNEHSVI
NT seq 4371 nt   +upstreamnt  +downstreamnt
atgaggctacccctgctcctggtttttgcctctgtcattccgggtgctgttctcctactg
gacaccaggcaatttttaatctataatgaagatcacaagcgctgcgtggatgcagtgagt
cccagtgccgtccaaaccgcagcttgcaaccaggatgccgaatcacagaaattccgatgg
gtgtccgaatctcagattatgagtgttgcatttaaattatgcctgggagtgccatcaaaa
acggactgggttgctatcactctctatgcctgtgactcaaaaagtgaatttcagaaatgg
gagtgcaaaaatgacacacttttggggatcaaaggagaagatttattttttaactacggc
aacagacaagaaaagaatattatgctctacaagggatcgggtttatggagcaggtggaag
atctatggaaccacagacaatctgtgctccagaggttatgaagccatgtatacgctacta
ggcaatgccaatggagcaacctgtgcattcccgttcaagtttgaaaacaagtggtacgca
gattgcacgagtgctgggcggtcggatggatggctctggtgcggaaccactactgactat
gacacagacaagctatttggatattgtccattgaaatttgagggcagtgaaagcttatgg
aataaagacccgctgaccagcgtttcctaccagataaactccaaatccgctttaacgtgg
caccaggcgaggaaaagctgccaacaacagaacgctgagctcctgagcatcacagagatt
catgagcaaacatacctgacaggattaaccagttccttgacctcaggactctggattgga
cttaacagtctgagcttcaacagcggttggcagtggagtgaccgcagtcctttccgatat
ttgaactggttaccaggaagtccatcagctgaacctggaaaaagctgtgtgtcactaaat
cctggaaaaaatgctaaatgggaaaatctggaatgtgttcagaaactgggctatatttgc
aaaaagggcaacaccactttaaattcttttgttattccctcagaaagtgatgtgcctact
cactgtcctagtcagtggtggccgtatgccggtcactgttacaagattcacagagatgag
aaaaaaatccagagggatgctctgaccacctgcaggaaggaaggcggtgacctcacaagt
atccacaccatcgaggaattggactttattatctcccagctaggatatgagccaaatgac
gaattgtggatcggcttaaatgacattaagattcaaatgtactttgagtggagtgatggg
acccctgtaacgtttaccaaatggcttcgtggagaaccaagccatgaaaacaacagacag
gaggattgtgtggtgatgaaaggcaaggatgggtactgggcagatcggggctgtgagtgg
cctcttggctacatctgcaagatgaaatcacgaagccaaggtccagaaatagtggaagtc
gaaaaaggctgcaggaaaggctggaaaaaacatcacttttactgctatatgattggacat
acgctttcaacatttgcagaagcaaaccaaacctgtaataatgagaatgcttatttaaca
actattgaagacagatatgaacaagccttcctgactagtttcgttggcttaaggcctgaa
aaatatttctggacaggactttcagatatacaaaccaaagggacttttcagtggaccatc
gaggaagaggttcggttcacccactggaattcagatatgccagggcgaaagccagggtgt
gttgccatgagaaccgggattgcagggggcttatgggatgttttgaaatgtgatgaaaag
gcaaaatttgtgtgcaagcactgggcagaaggagtaacccacccaccgaagcccacgacg
actcccgaacccaaatgtccggaggattggggcgccagcagtagaacaagcttgtgtttc
aagctgtatgcaaaaggaaaacatgagaagaaaacgtggtttgaatctcgagatttttgt
cgagctctgggtggagacttagctagcatcaataacaaagaggaacagcaaacaatatgg
cgattaataacagctagtggaagctaccacaaactgttttggttgggattgacatatgga
agcccttcagaaggttttacttggagtgatggttctcctgtttcatatgaaaactgggct
tatggagaacctaataattatcaaaatgttgaatactgtggtgagctgaaaggtgaccct
actatgtcttggaatgatattaattgtgaacaccttaacaactggatttgccagatacaa
aaaggacaaacaccaaaacctgagccaacaccagctcctcaagacaatccaccagttact
gaagatgggtgggttatttacaaagactaccagtattatttcagcaaagagaaggaaacc
atggacaatgcgcgagcgttttgcaagaggaattttggtgatcttgtttctattcaaagt
gaaagtgaaaagaagtttctatggaaatatgtaaacagaaatgatgcacagtctgcatat
tttattggtttattgatcagcttggataaaaagtttgcttggatggatggaagcaaagtg
gattacgtgtcttgggccacaggtgaacccaattttgcaaatgaagatgaaaactgtgtg
accatgtattcaaattcagggttttggaatgacattaactgtggctatccaaacgccttc
atttgccagcgacataacagtagtatcaatgctaccacagttatgcctaccatgccctcg
gtcccatcagggtgcaaggaaggttggaatttctacagcaacaagtgtttcaaaatcttt
ggatttatggaagaagaaagaaaaaattggcaagaggcacgaaaagcttgtataggcttt
ggagggaatctggtctccatacaaaatgaaaaagagcaagcatttcttacctatcacatg
aaggactccactttcagtgcctggactgggctgaatgatgtcaattcagaacacacgttc
ctttggacggatggacgaggagtccattacacaaactgggggaaaggttaccctggtgga
agaagaagcagtctttcttatgaagatgctgactgtgttgttattattggaggtgcatca
aatgaagcaggaaaatggatggatgatacctgcgacagtaaacgaggctacatatgccag
acacgatccgacccttccttgactaatcctccagcaacgattcaaacagatggctttgtt
aaatatggcaaaagcagctattcactcatgagacaaaaatttcaatggcatgaagcggag
acatactgcaagcttcacaattcccttatagccagcattctggatccctacagtaatgca
tttgcgtggctgcagatggaaacatctaatgaacgtgtgtggatcgccctgaacagtaac
ttgactgataatcaatacacttggactgataagtggagggtgaggtacactaactgggct
gctgatgagcccaaattgaaatcagcatgtgtttatctggatcttgatggctactggaag
acagcacattgcaatgaaagtttttactttctctgtaaaagatcagatgaaatccctgct
actgaacccccacaactgcctggcagatgcccggagtcagatcacacagcatggattcct
ttccatggtcactgttactatattgagtcctcatatacaagaaactggggccaagcttct
ctggaatgtcttcgaatgggttcctctctggtttccattgaaagtgctgcagaatccagt
tttctgtcatatcgggttgagccacttaaaagtaaaaccaatttttggataggattgttc
agaaatgttgaagggacgtggctgtggataaataacagtccggtctcctttgtcaactgg
aacacaggagatccctctggtgaacggaatgattgtgtagctttacatgcgtcttctggg
ttttggagtaatattcactgttcatcctacaaaggatatatttgtaaaagaccaaaaatt
attgatgctaaacctactcatgaattacttacaacaaaagctgacacaaggaagatggac
ccttctaaaccgtcttccaacgtggccggagtagtcatcattgtgatcctcctgatttta
acgggtgctggccttgccgcctatttcttttataagaaaagacgtgtgcacctacctcaa
gagggcgcctttgaaaacactctgtattttaacagtcagtcaagcccaggaactagtgat
atgaaagatctcgtgggcaatattgaacagaatgaacactcggtcatctag

KEGG   Homo sapiens (human): 9902
Entry
9902              CDS       T01001                                 
Symbol
MRC2, CD280, CLEC13E, ENDO180, UPARAP
Name
(RefSeq) mannose receptor C-type 2
  KO
K06560  mannose receptor, C type
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagosome
hsa05152  Tuberculosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    9902 (MRC2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    9902 (MRC2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    9902 (MRC2)
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors [BR:hsa04054]
    9902 (MRC2)
   04090 CD molecules [BR:hsa04090]
    9902 (MRC2)
   04091 Lectins [BR:hsa04091]
    9902 (MRC2)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Phagocytosis
   C-lectin receptors
    9902 (MRC2)
Pattern recognition receptors [BR:hsa04054]
 Membrane-bound pattern recognition receptors
  C-type lectin receptors
   9902 (MRC2)
CD molecules [BR:hsa04090]
 Proteins
  9902 (MRC2)
Lectins [BR:hsa04091]
 C-Type lectins
  Group 6: Mannose receptor family
   9902 (MRC2)
SSDB
Motif
Pfam: Lectin_C fn2 UL45 Xlink Chordopox_A33R
Other DBs
NCBI-GeneID: 9902
NCBI-ProteinID: NP_006030
OMIM: 612264
HGNC: 16875
Ensembl: ENSG00000011028
UniProt: Q9UBG0
Structure
LinkDB
Position
17:62627670..62693597
AA seq 1479 aa
MGPGRPAPAPWPRHLLRCVLLLGCLHLGRPGAPGDAALPEPNVFLIFSHGLQGCLEAQGG
QVRVTPACNTSLPAQRWKWVSRNRLFNLGTMQCLGTGWPGTNTTASLGMYECDREALNLR
WHCRTLGDQLSLLLGARTSNISKPGTLERGDQTRSGQWRIYGSEEDLCALPYHEVYTIQG
NSHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWD
KDQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLTGYSSTLWIGL
NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALPYVCK
KKPNATAEPTPPDRWANVKVECEPSWQPFQGHCYRLQAEKRSWQESKKACLRGGGDLVSI
HSMAELEFITKQIKQEVEELWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLED
CVTIWGPEGRWNDSPCNQSLPSICKKAGQLSQGAAEEDHGCRKGWTWHSPSCYWLGEDQV
TYSEARRLCTDHGSQLVTITNRFEQAFVSSLIYNWEGEYFWTALQDLNSTGSFFWLSGDE
VMYTHWNRDQPGYSRGGCVALATGSAMGLWEVKNCTSFRARYICRQSLGTPVTPELPGPD
PTPSLTGSCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQELGAQLLSLASYEEE
HFVANMLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDD
DIRGCAVLDLASLQWVAMQCDTQLDWICKIPRGTDVREPDDSPQGRREWLRFQEAEYKFF
EHHSTWAQAQRICTWFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGRF
RWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALPYICKRSNVTKETQ
PPDLPTTALGGCPSDWIQFLNKCFQVQGQEPQSRVKWSEAQFSCEQQEAQLVTITNPLEQ
AFITASLPNVTFDLWIGLHASQRDFQWVEQEPLMYANWAPGEPSGPSPAPSGNKPTSCAV
VLHSPSAHFTGRWDDRSCTEETHGFICQKGTDPSLSPSPAALPPAPGTELSYLNGTFRLL
QKPLRWHDALLLCESRNASLAYVPDPYTQAFLTQAARGLRTPLWIGLAGEEGSRRYSWVS
EEPLNYVGWQDGEPQQPGGCTYVDVDGAWRTTSCDTKLQGAVCGVSSGPPPPRRISYHGS
CPQGLADSAWIPFREHCYSFHMELLLGHKEARQRCQRAGGAVLSILDEMENVFVWEHLQS
YEGQSRGAWLGMNFNPKGGTLVWQDNTAVNYSNWGPPGLGPSMLSHNSCYWIQSNSGLWR
PGACTNITMGVVCKLPRAEQSSFSPSALPENPAALVVVLMAVLLLLALLTAALILYRRRQ
SIERGAFEGARYSRSSSSPTEATEKNILVSDMEMNEQQE
NT seq 4440 nt   +upstreamnt  +downstreamnt
atggggcccggccggccggcccccgcgccctggcctcgtcacctgctgcgctgcgtcctg
ctcctcgggtgcctgcacctcggccgtcccggcgcccctggggacgccgccctcccggaa
cccaacgtcttcctcatcttcagccatggactgcagggctgcctggaggcccagggcggg
caggtcagagtcaccccggcttgcaataccagcctccctgcccagcgctggaagtgggtc
tcccgaaaccggctattcaacctgggtaccatgcagtgcctgggcacaggctggccaggc
accaacaccacggcctccctgggcatgtatgagtgtgaccgggaagcactgaatcttcgc
tggcattgtcgtacactgggtgaccagctgtccttgctcctgggggcccgcaccagcaac
atatccaagcctggcacccttgagcgtggtgaccagacccgcagtggccagtggcgcatc
tacggcagcgaggaggacctatgtgctctgccctaccacgaggtctacaccatccaggga
aactcccacggaaagccgtgcaccatccccttcaaatatgacaaccagtggttccacggc
tgcaccagcacgggccgcgaggatggtcacctgtggtgtgccaccacccaggactacggc
aaagacgagcgctggggcttctgccccatcaagagtaacgactgcgagaccttctgggac
aaggaccagctgactgacagctgctaccagtttaacttccagtccacgctgtcgtggagg
gaggcctgggccagctgcgagcagcagggtgcggatctgctgagcatcacggagatccac
gagcagacctacatcaacggcctcctcactgggtacagctccaccctgtggatcggcttg
aatgacttggacacgagcggaggctggcagtggtcggacaactcgcccctcaagtacctc
aactgggagagtgaccagccggacaaccccagtgaggagaactgtggagtgatccgcact
gagtcctcgggcggctggcagaaccgtgactgcagcatcgcgctgccctatgtgtgcaag
aagaagcccaacgccacggccgagcccacccctccagacaggtgggccaatgtgaaggtg
gagtgcgagccgagctggcagcccttccagggccactgctaccgcctgcaggccgagaag
cgcagctggcaggagtccaagaaggcatgtctacggggcggtggcgacctggtcagcatc
cacagcatggcggagctggaattcatcaccaagcagatcaagcaagaggtggaggagctg
tggatcggcctcaacgatttgaaactgcagatgaattttgagtggtctgacgggagcctt
gtgagcttcacccactggcacccctttgagcccaacaacttccgggacagtctggaggac
tgtgtcaccatctggggcccggaaggccgctggaacgacagtccctgtaaccagtccttg
ccatccatctgcaagaaggcaggccagctgagccagggggccgccgaggaggaccatggc
tgccggaagggttggacgtggcacagcccatcctgctactggctgggagaagaccaagtg
acctacagtgaggcccggcgcctgtgcactgaccatggctctcagctggtcaccatcacc
aacaggttcgagcaggccttcgtcagcagcctcatctacaactgggagggcgagtacttc
tggacggccctgcaggacctcaacagcaccggctccttcttctggctcagtggggatgaa
gtcatgtacacccactggaaccgggaccagcccgggtacagccgtgggggctgcgtggcg
ctggccactggcagcgccatggggctgtgggaggtgaagaactgtacctcgttccgggcc
cgctacatctgccggcagagcctgggcactccagtgacgccggagctgccggggccagat
cccacgcccagcctcactggctcctgtccccagggctgggcctcggacaccaaactccgg
tattgctataaggtgttcagctcagagcggctgcaggacaagaagagctgggtccaggcc
cagggggcctgccaggagctgggggcccagctgctgagcctggccagctacgaggaggag
cactttgtggccaacatgctcaacaagatcttcggtgaatcagaacccgagatccacgag
cagcactggttctggatcggcctgaaccgtcgggatcccagagggggtcagagttggcgc
tggagcgacggcgtagggttctcttaccacaatttcgaccggagccggcacgacgacgac
gacatccgaggctgtgcggtgctggacctggcctccctgcagtgggtggccatgcagtgc
gacacacagctggactggatctgcaagatccccagaggtacggacgtgcgggagcccgac
gacagccctcaaggccgacgggaatggctgcgcttccaggaggccgagtacaagttcttt
gagcaccactccacgtgggcgcaggcgcagcgcatctgcacgtggttccaggccgagctg
acctcggtgcacagccaggcggagctagacttcctgagccacaacttgcagaagttctcc
cgggcccaggagcagcactggtggatcggcctgcacacctctgagagcgatgggcgcttc
agatggacagatggttccattataaacttcatctcctgggcaccaggcaaacctcggcct
gtcggcaaggacaagaagtgcgtgtacatgacagccagccgagaggactggggggaccag
aggtgcctgacagccttgccctacatctgcaagcgcagcaacgtcaccaaagaaacgcag
cccccagacctgccaactacagccctggggggctgcccctctgactggatccagttcctc
aacaagtgttttcaggtccagggccaggaaccccagagccgggtgaagtggtcagaggca
cagttctcctgtgaacagcaagaggcccagctggtcaccatcacaaaccccttagagcaa
gcattcatcacagccagcctgcccaatgtgacctttgacctttggattggcctccatgcc
tcgcagagggacttccagtgggtggagcaggagcctttgatgtatgccaactgggcacct
ggggagccctctggccctagccctgctcccagtggcaacaaaccgaccagctgtgcagtg
gtcctgcacagcccctcagcccacttcactggccgctgggacgatcggagctgcacggag
gagacccatggcttcatctgccagaagggcacggacccctccctgagcccgtccccagca
gcgctgccccccgccccgggcactgagctctcctacctcaacggcaccttccggctgctt
cagaagccgctgcgctggcacgatgccctcctgctgtgtgagagccgcaatgccagcctg
gcctacgtgcccgacccctacacccaggccttcctcacgcaggctgcccgagggctgcgc
acgccgctctggattgggctggctggcgaggagggctctcggcggtactcctgggtctca
gaggagccgctgaactacgtgggctggcaggacggggagccgcagcagccggggggctgt
acctacgtagatgtggacggggcctggcgcaccaccagctgtgacaccaagctgcagggg
gctgtgtgtggggttagcagtgggccccctcctccccgaagaataagctaccatggcagc
tgtccccagggactggcagactccgcgtggattcccttccgggagcactgctattctttc
cacatggagctgctgctgggccacaaggaggcgcgacagcgctgccagagagcgggtggg
gccgtcctgtctatcctggatgagatggagaatgtgtttgtctgggagcacctgcagagc
tatgagggccagagtcggggcgcctggctgggcatgaacttcaaccccaaaggaggcact
ctggtctggcaggacaacacagctgtgaactactccaactgggggcccccgggcttgggc
cccagcatgctgagccacaacagctgctactggattcagagcaacagcgggctatggcgc
cccggcgcttgcaccaacatcaccatgggtgtcgtctgcaagcttcctcgtgctgagcag
agcagcttctccccatcagcgcttccagagaacccagcggccctggtggtggtgctgatg
gcggtgctgctgctcctggccttgctgaccgcagccctcatcctttaccggaggcgccag
agcatcgagcgcggggcctttgagggtgcccgctacagccgcagcagctccagccccacc
gaggccactgagaagaacatcctggtgtcagacatggaaatgaatgagcaacaagaatag

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