Homo sapiens (human): 23324 Help Entry 23324             CDS       T01001                                  Symbol MAN2B2, CDG1EE, EpMAN Name (RefSeq) mannosidase alpha class 2B member 2   KO K12312   epididymis-specific alpha-mannosidase [EC:3.2.1.24] Organism hsa  Homo sapiens (human) Pathway hsa00511   Other glycan degradation Disease H00118   Congenital disorders of glycosylation type I Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09107 Glycan biosynthesis and metabolism    00511 Other glycan degradation     23324 (MAN2B2) Enzymes [BR:hsa01000]  3. Hydrolases   3.2  Glycosylases    3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds     3.2.1.24  alpha-mannosidase      23324 (MAN2B2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Glyco_hydro_38N Alpha-mann_mid Glyco_hydro_38C Glyco_hydro38C2 DUF4232 Motif Other DBs NCBI-GeneID:  23324 NCBI-ProteinID:  NP_056089 OMIM:  618899 HGNC:  29623 Ensembl:  ENSG00000013288 UniProt:  Q9Y2E5 LinkDB All DBs Position 4:6575189..6623362 Genome browser AA seq 1009 aa AA seqDB search MGQLCWLPLLAPLLLLRPPGVQSAGPIRAFVVPHSHMDVGWVYTVQESMRAYAANVYTSV VEELARGQQRRFIAVEQEFFRLWWDGVASDQQKYQVRQLLEEGRLEFVIGGQVMHDEAVT HLDDQILQLTEGHGFLYETFGIRPQFSWHVDPFGASATTPTLFALAGFNAHLGSRIDYDL KAAMQEARGLQFVWRGSPSLSERQEIFTHIMDQYSYCTPSHIPFSNRSGFYWNGVAVFPK PPQDGVYPNMSEPVTPANINLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNASVQFA NMDPLLDHINSHAAELGVSVQYATLGDYFRALHALNVTWRVRDHHDFLPYSTEPFQAWTG FYTSRSSLKGLARRASALLYAGESMFTRYLWPAPRGHLDPTWALQQLQQLRWAVSEVQHH DAITGTESPKVRDMYATHLASGMLGMRKLMASIVLDELQPQAPMAASSDAGPAGHFASVY NPLAWTVTTIVTLTVGFPGVRVTDEAGHPVPSQIQNSTETPSAYDLLILTTIPGLSYRHY NIRPTAGAQEGTQEPAATVASTLQFGRRLRRRTSHAGRYLVPVANDCYIVLLDQDTNLMH SIWERQSNRTVRVTQEFLEYHVNGDVKQGPISDNYLFTPGKAAVPAWEAVEMEIVAGQLV TEIRQYFYRNMTAQNYTYAIRSRLTHVPQGHDGELLCHRIEQEYQAGPLELNREAVLRTS TNLNSQQVIYSDNNGYQMQRRPYVSYVNNSIARNYYPMVQSAFMEDGKSRLVLLSERAHG ISSQGNGQVEVMLHRRLWNNFDWDLGYNLTLNDTSVVHPVLWLLLGSWSLTTALRQRSAL ALQHRPVVLFGDLAGTAPKLPGPQQQEAVTLPPNLHLQILSIPGWRYSSNHTEHSQNLRK GHRGEAQADLRRVLLRLYHLYEVGEDPVLSQPVTVNLEAVLQALGSVVAVEERSLTGTWD LSMLHRWSWRTGPGRHRGDTTSPSRPPGGPIITVHPKEIRTFFIHFQQQ NT seq 3030 nt NT seq  +upstreamnt  +downstreamnt atggggcagctgtgctggctgccgctgctggcaccgctcctgttgctgcgaccgccaggg gtccagtccgccggccccatccgggccttcgtggtgccccacagccacatggacgtgggc tgggtctacactgtgcaggaaagcatgcgggcgtacgccgccaatgtctacacctcagtg gtggaagagctggcccgcggccagcagcgccggttcatcgctgtggagcaggagtttttc cggctgtggtgggatggcgtcgcctcggaccagcagaaataccaggtccgccagctcctg gaggaaggacgcctggaatttgtcatcggaggccaggtcatgcatgacgaggctgtgacg caccttgatgaccagatcctgcagctcacagaaggacacgggtttctctatgaaacattt gggatccggccacagttctcctggcacgttgacccgtttggcgcctctgccacgacgccc accctatttgcgctggcgggcttcaatgcccacctcggctcccggatcgactacgacctg aaggcagccatgcaggaggcccgggggctgcagttcgtgtggcgagggtccccatccctc tcagagcggcaggaaatcttcacgcacatcatggaccagtacagctactgcaccccgtcc cacatccctttctccaacaggtcaggattttactggaatggcgtggctgtcttccccaag cctccccaagatggggtgtaccccaacatgagtgagcctgtcaccccagccaacatcaac ctctatgccgaggccctggtggccaacgtgaagcagagggccgcctggttccggacaccg cacgtcctctggccctggggatgtgacaagcagttcttcaatgcctcggtgcagtttgcc aacatggacccgctgctggaccacatcaacagccatgctgccgagctcggtgtctcggtg cagtatgccacgctgggcgactacttccgtgccctgcacgctctcaatgtcacctggcgt gtccgcgaccaccacgacttcctgccctattccacagaaccattccaggcctggacgggc ttctacacgtcccgcagctcactgaaggggctggcccggcgagccagcgccttgttgtat gccggggagtccatgttcacacgctacctgtggccggccccccgtgggcatctggacccc acctgggccctgcagcagctccagcagcttcgctgggccgtctccgaggtccagcaccat gatgccatcactgggactgagtcccccaaggtgagagacatgtacgcaacgcacctggcc tcggggatgctgggcatgcgcaagctgatggcctccatcgtcctagatgagctccagccc caggcacccatggcggccagctccgatgcaggacctgcaggacattttgcctcggtctac aacccgctggcctggacggtcaccaccatcgtcaccctgactgttggtttccctggagtc cgcgtcacagatgaggcgggccacccagtgccctcgcagatccagaactcaacagagacc ccatctgcgtatgacctgcttattctgaccacaatcccaggcctcagttaccggcactac aacatcagacccactgcaggggcccaagagggcacccaggagccggctgccactgtggcg agcacccttcaatttggccgcaggctgaggagacgcaccagccatgcgggcaggtacttg gtgcctgtggcaaacgactgctacattgtgctgctcgaccaggataccaacctgatgcac agcatctgggagagacagagtaaccgaacggtgcgcgtgacccaggaattcctggagtac cacgtcaacggggatgtgaaacagggccccatttccgataactacctgttcacaccgggc aaggccgcggtgcctgcgtgggaagctgtggaaatggagattgtggcgggacagcttgtg actgagatccggcagtacttctacaggaacatgacagcacagaattacacgtatgcaatc cgctcccggctcacccatgtgccgcagggccatgacggggagctgctctgccaccggata gagcaggagtaccaagccggccccctggagctgaaccgtgaggctgtcctgaggaccagc accaacctaaacagccagcaggtcatctactcagacaacaacggctaccagatgcagcgg aggccctacgtttcctatgtgaacaacagcatcgcccggaattactaccccatggttcag tcggccttcatggaggatggcaaaagcaggcttgtgttgctgtcggagcgggcacatggc atctccagccaagggaatgggcaggtggaggtcatgctccaccggcggctgtggaacaac ttcgactgggacctgggctacaacctcacgctgaacgacacctcagtcgtccacccagtg ctctggcttctgctgggatcctggtccctcaccactgccctgcgccagaggagcgcactg gcgctgcagcacaggcccgtggtgctgttcggagacctcgctgggactgcgccgaagctc ccaggaccccagcagcaagaggccgtgacgctgcccccgaatcttcacctgcagatcctg agcatccctggctggcgctacagctccaaccacacggagcactctcagaatctccggaaa ggccatcgaggggaagcccaggctgacctccgccgtgtcctgctgcggctctaccaccta tatgaagtgggcgaggacccagtcctgtctcagccagtgacagtgaatctggaggctgtg ctgcaggcgctggggtccgtggtggcagtggaggagcgctcgctcacagggacctgggat ttgagcatgctgcaccgctggagctggaggacggggcctggccgccacagaggtgacacc acctctccctcgaggccaccaggaggccccatcatcaccgtccacccaaaggaaatccgg acgttctttattcactttcaacagcagtga

Homo sapiens (human): 4123 Help Entry 4123              CDS       T01001                                  Symbol MAN2C1, CDDG2, MAN6A8, MANA, MANA1 Name (RefSeq) mannosidase alpha class 2C member 1   KO K01191   alpha-mannosidase [EC:3.2.1.24] Organism hsa  Homo sapiens (human) Pathway hsa00511   Other glycan degradation Disease H02767   Congenital disorder of deglycosylation Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09107 Glycan biosynthesis and metabolism    00511 Other glycan degradation     4123 (MAN2C1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hsa04131]     4123 (MAN2C1) Enzymes [BR:hsa01000]  3. Hydrolases   3.2  Glycosylases    3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds     3.2.1.24  alpha-mannosidase      4123 (MAN2C1) Membrane trafficking [BR:hsa04131]  Autophagy   Cytoplasm to vacuolar targeting (CVT) pathway    Selective cargos     4123 (MAN2C1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Glyco_hydro_38N Ams1-like_1st Glyco_hydro_38C Alpha-mann_mid Glyco_hydro38C2 Motif Other DBs NCBI-GeneID:  4123 NCBI-ProteinID:  NP_006706 OMIM:  154580 HGNC:  6827 Ensembl:  ENSG00000140400 UniProt:  Q9NTJ4 A0A140VJN9 LinkDB All DBs Position 15:complement(75355792..75368607) Genome browser AA seq 1040 aa AA seqDB search MAAAPALKHWRTTLERVEKFVSPLYFTDCNLRGRLFGASCPVAVLSSFLTPERLPYQEAV QRDFRPAQVGDSFGPTWWTCWFRVELTIPEAWVGQEVHLCWESDGEGLVWRDGEPVQGLT KEGEKTSYVLTDRLGERDPRSLTLYVEVACNGLLGAGKGSMIAAPDPEKMFQLSRAELAV FHRDVHMLLVDLELLLGIAKGLGKDNQRSFQALYTANQMVNVCDPAQPETFPVAQALASR FFGQHGGESQHTIHATGHCHIDTAWLWPFKETVRKCARSWVTALQLMERNPEFIFACSQA QQLEWVKSRYPGLYSRIQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQE FGKMCSEFWLPDTFGYSAQLPQIMHGCGIRRFLTQKLSWNLVNSFPHHTFFWEGLDGSRV LVHFPPGDSYGMQGSVEEVLKTVANNRDKGRANHSAFLFGFGDGGGGPTQTMLDRLKRLS NTDGLPRVQLSSPRQLFSALESDSEQLCTWVGELFLELHNGTYTTHAQIKKGNRECERIL HDVELLSSLALARSAQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQMVAEEAMCHYEDIR SHGNTLLSAAAAALCAGEPGPEGLLIVNTLPWKRIEVMALPKPGGAHSLALVTVPSMGYA PVPPPTSLQPLLPQQPVFVVQETDGSVTLDNGIIRVKLDPTGRLTSLVLVASGREAIAEG AVGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISPN SRLSQEVVLDVGCPYVRFHTEVHWHEAHKFLKVEFPARVRSSQATYEIQFGHLQRPTHYN TSWDWARFEVWAHRWMDLSEHGFGLALLNDCKYGASVRGSILSLSLLRAPKAPDATADTG RHEFTYALMPHKGSFQDAGVIQAAYSLNFPLLALPAPSPAPATSWSAFSVSSPAVVLETV KQAESSPQRRSLVLRLYEAHGSHVDCWLHLSLPVQEAILCDLLERPDPAGHLTLRDNRLK LTFSPFQVLSLLLVLQPPPH NT seq 3123 nt NT seq  +upstreamnt  +downstreamnt atggcggctgcgccggccttgaagcactggcgcaccacgctggagcgggtggagaagttc gtgtcgccgctctactttaccgactgtaacctccgcggcaggctttttggggccagctgc cctgtggctgtgctctccagcttcctgacgccggagagacttccctaccaggaggcagtc cagcgggacttccgccccgcgcaggtcggcgacagcttcggacccacatggtggacctgc tggttccgggtggagctgaccatcccagaggcatgggtgggccaggaagttcacctttgc tgggaaagtgatggagaaggtctggtgtggcgtgatggagaacctgtccagggtttaacc aaagagggtgagaagaccagctatgtcctgactgacaggctgggggaaagagacccccga agcctcactctctatgtggaagtagcctgcaatgggctcctgggggccgggaagggaagc atgattgcagcccctgaccctgagaagatgttccagctgagccgggctgagctagctgtg ttccaccgggatgtccacatgctcctggtggatctggagctgctgctgggcatagccaag ggcctcgggaaggacaaccagcgcagcttccaggccctgtacacagccaatcagatggtg aacgtgtgtgaccctgcccagcccgagaccttcccagtggcccaggccctggcctccagg ttctttggccaacatgggggtgaaagccaacacaccattcatgccacagggcactgccac attgatacagcctggctttggcccttcaaagagactgtgaggaaatgtgcccggagctgg gtgaccgccctgcagctcatggagcggaaccctgagttcatctttgcctgctcccaggcg cagcagctggaatgggtgaagagccgctaccctggcctgtactcccgcatccaggagttt gcgtgccgtgggcagtttgtgcctgtggggggcacctgggtggagatggatgggaacctg cccagtggagaggccatggtgaggcagtttttgcagggccagaacttctttctgcaggag tttgggaagatgtgctctgagttctggctgccggacacctttggctactcagcacagctc ccccagatcatgcacggctgtggcatcaggcgctttctcacccagaaattgagctggaat ttggtgaactccttcccacaccatacatttttctgggagggcctggatggctcccgtgta ctggtccacttcccacctggcgactcctatgggatgcagggcagcgtggaggaggtgctg aagaccgtggccaacaaccgggacaaggggcgggccaaccacagtgccttcctctttggc tttggggatgggggtggtggccccacccagaccatgctggaccgcctgaagcgcctgagc aatacggatgggctgcccagggtgcagctatcttctccaagacagctcttctcagcactg gagagtgactcagagcagctgtgcacgtgggttggggagctcttcttggagctgcacaat ggcacatacaccacccatgcccagatcaagaaggggaaccgggaatgtgagcggatcctg cacgacgtggagctgctcagtagcctggccctggcccgcagtgcccagttcctataccca gcagcccagctgcagcacctctggaggctccttcttctgaaccagttccatgatgtggtg actggaagctgcatccagatggtggcagaggaagccatgtgccattatgaagacatccgt tcccatggcaatacactgctcagcgctgcagccgcagccctgtgtgctggggagccaggt cctgagggcctcctcatcgtcaacacactgccctggaagcggatcgaagtgatggccctg cccaaaccgggcggggcccacagcctagccctggtgacagtgcccagcatgggctatgct cctgttcctccccccacctcactgcagcccctgctgccccagcagcctgtgttcgtagtg caagagactgatggctccgtgactctggacaatggcatcatccgagtgaagctggaccca actggtcgcctgacgtccttggtcctggtggcctctggcagggaggccattgctgagggc gccgtggggaaccagtttgtgctatttgatgatgtccccttgtactgggatgcatgggac gtcatggactaccacctggagacacggaagcctgtgctgggccaggcagggaccctggca gtgggcaccgagggcggcctgcggggcagcgcctggttcttgctacagatcagccccaac agtcggcttagccaggaggttgtgctggacgttggctgcccctatgtccgcttccacacc gaggtacactggcatgaggcccacaagttcctgaaggtggagttccctgctcgcgtgcgg agttcccaggccacctatgagatccagtttgggcacctgcagcgacctacccactacaat acctcttgggactgggctcgatttgaggtgtgggcccatcgctggatggatctgtcagaa cacggctttgggctggccctgctcaacgactgcaagtatggcgcgtcagtgcgaggcagc atcctcagcctctcgctcttgcgggcgcctaaagccccggacgctactgctgacacgggg cgccacgagttcacctatgcactgatgccgcacaagggctctttccaggatgctggcgtt atccaagctgcctacagcctaaacttccccctgttggctctgccagcccccagcccagcg cccgccacctcctggagtgcgttttccgtgtcttcacccgcggtcgtattggagaccgtc aagcaggcggagagcagcccccagcgccgctcgctggtcctgaggctgtatgaggcccac ggcagccacgtggactgctggctgcacttgtcgctgccggttcaggaggccatcctctgc gatctcttggagcgaccagaccctgctggccacttgacccttcgggacaaccgcctgaag ctcaccttttctcccttccaagtgctgtccctgttgctcgtgcttcagcctccgccacac tga

Homo sapiens (human): 4125 Help Entry 4125              CDS       T01001                                  Symbol MAN2B1, LAMAN, MANB Name (RefSeq) mannosidase alpha class 2B member 1   KO K12311   lysosomal alpha-mannosidase [EC:3.2.1.24] Organism hsa  Homo sapiens (human) Pathway hsa00511   Other glycan degradation hsa04142   Lysosome Disease H00139   alpha-Mannosidosis H00422   Glycoproteinoses Drug target Velmanase alfa:  D11024<US> Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09107 Glycan biosynthesis and metabolism    00511 Other glycan degradation     4125 (MAN2B1)  09140 Cellular Processes   09141 Transport and catabolism    04142 Lysosome     4125 (MAN2B1) Enzymes [BR:hsa01000]  3. Hydrolases   3.2  Glycosylases    3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds     3.2.1.24  alpha-mannosidase      4125 (MAN2B1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Glyco_hydro_38N Glyco_hydro_38C Alpha-mann_mid Glyco_hydro38C2 Laman-like_dom Motif Other DBs NCBI-GeneID:  4125 NCBI-ProteinID:  NP_000519 OMIM:  609458 HGNC:  6826 Ensembl:  ENSG00000104774 UniProt:  O00754 LinkDB All DBs Position 19:complement(12646512..12666742) Genome browser AA seq 1011 aa AA seqDB search MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQP NMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVE IAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLE DTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWR ASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVA TAQGRYYRTNHTVMTMGSDFQYENANMWFKNLDKLIRLVNAQQAKGSSVHVLYSTPACYL WELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVG LAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNAL ARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDP NGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRRS WSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAY IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNT RIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRG RHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSV HLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQ LREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG NT seq 3036 nt NT seq  +upstreamnt  +downstreamnt atgggcgcctacgcgcgggcttcgggggtctgcgctcgcggctgcctggactcagcaggc ccctggaccatgtcccgcgccctgcggccaccgctcccgcctctctgctttttccttttg ttgctggcggctgccggtgctcgggccgggggatacgagacatgccccacagtgcagccg aacatgctgaacgtgcacctgctgcctcacacacatgatgacgtgggctggctcaaaacc gtggaccagtacttttatggaatcaagaatgacatccagcacgccggtgtgcagtacatc ctggactcggtcatctctgccttgctggcagatcccacccgtcgcttcatttacgtggag attgccttcttctcccgttggtggcaccagcagacaaatgccacacaggaagtcgtgcga gaccttgtgcgccaggggcgcctggagttcgccaatggtggctgggtgatgaacgatgag gcagccacccactacggtgccatcgtggaccagatgacacttgggctgcgctttctggag gacacatttggcaatgatgggcgaccccgtgtggcctggcacattgaccccttcggccac tctcgggagcaggcctcgctgtttgcgcagatgggcttcgacggcttcttctttgggcgc cttgattatcaagataagtgggtacggatgcagaagctggagatggagcaggtgtggcgg gccagcaccagcctgaagcccccgaccgcggacctcttcactggtgtgcttcccaatggt tacaacccgccaaggaatctgtgctgggatgtgctgtgtgtcgatcagccgctggtggag gaccctcgcagccccgagtacaacgccaaggagctggtcgattacttcctaaatgtggcc actgcccagggccggtattaccgcaccaaccacactgtgatgaccatgggctcggacttc caatatgagaatgccaacatgtggttcaagaaccttgacaagctcatccggctggtaaat gcgcagcaggcaaaaggaagcagtgtccatgttctctactccacccccgcttgttacctc tgggagctgaacaaggccaacctcacctggtcagtgaaacatgacgacttcttcccttac gcggatggcccccaccagttctggaccggttacttttccagtcggccggccctcaaacgc tacgagcgcctcagctacaacttcctgcaggtgtgcaaccagctggaggcgctggtgggc ctggcggccaacgtgggaccctatggctccggagacagtgcacccctcaatgaggcgatg gctgtgctccagcatcacgacgccgtcagcggcacctcccgccagcacgtggccaacgac tacgcgcgccagcttgcggcaggctgggggccttgcgaggttcttctgagcaacgcgctg gcgcggctcagaggcttcaaagatcacttcaccttttgccaacagctaaacatcagcatc tgcccgctcagccagacggcggcgcgcttccaggtcatcgtttataatcccctggggcgg aaggtgaattggatggtacggctgccggtcagcgaaggcgttttcgttgtgaaggacccc aatggcaggacagtgcccagcgatgtggtaatatttcccagctcagacagccaggcgcac cctccggagctgctgttctcagcctcactgcccgccctgggcttcagcacctattcagta gcccaggtgcctcgctggaagccccaggcccgcgcaccacagcccatccccagaagatcc tggtcccctgctttaaccatcgaaaatgagcacatccgggcaacgtttgatcctgacaca gggctgttgatggagattatgaacatgaatcagcaactcctgctgcctgttcgccagacc ttcttctggtacaacgccagtataggtgacaacgaaagtgaccaggcctcaggtgcctac atcttcagacccaaccaacagaaaccgctgcctgtgagccgctgggctcagatccacctg gtgaagacacccttggtgcaggaggtgcaccagaacttctcagcttggtgttcccaggtg gttcgcctgtacccaggacagcggcacctggagctagagtggtcggtggggccgatacct gtgggcgacacctgggggaaggaggtcatcagccgttttgacacaccgctggagacaaag ggacgcttctacacagacagcaatggccgggagatcctggagaggaggcgggattatcga cccacctggaaactgaaccagacggagcccgtggcaggaaactactatccagtcaacacc cggatttacatcacggatggaaacatgcagctgactgtgctgactgaccgctcccagggg ggcagcagcctgagagatggctcgctggagctcatggtgcaccgaaggctgctgaaggac gatggacgcggagtatcggagccactaatggagaacgggtcgggggcgtgggtgcgaggg cgccacctggtgctgctggacacagcccaggctgcagccgccggacaccggctcctggcg gagcaggaggtcctggcccctcaggtggtgctggccccgggtggcggcgccgcctacaat ctcggggctcctccgcgcacgcagttctcagggctgcgcagggacctgccgccctcggtg cacctgctcacgctggccagctggggccccgaaatggtgctgctgcgcttggagcaccag tttgccgtaggagaggattccggacgtaacctgagcgcccccgttaccttgaacttgagg gacctgttctccaccttcaccatcacccgcctgcaggagaccacgctggtggccaaccag ctccgcgaggcagcctccaggctcaagtggacaacaaacacaggccccacaccccaccaa actccgtaccagctggacccggccaacatcacgctggaacccatggaaatccgcactttc ctggcctcagttcaatggaaggaggtggatggttag

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