KEGG   Homo sapiens (human): 23369
Entry
23369             CDS       T01001                                 

Gene name
PUM2, PUMH2, PUML2
Definition
(RefSeq) pumilio RNA binding family member 2
  KO
K17943  pumilio RNA-binding family
Organism
hsa  Homo sapiens (human)
Pathway
hsa05017  Spinocerebellar ataxia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    23369 (PUM2)
SSDB
Motif
Pfam: PUF PC4
Other DBs
NCBI-GeneID: 23369
NCBI-ProteinID: NP_056132
OMIM: 607205
HGNC: 14958
Ensembl: ENSG00000055917
Vega: OTTHUMG00000122098
Pharos: Q8TB72(Tbio)
UniProt: Q8TB72
LinkDB
Structure
PDB: 
3Q0Q 3Q0R 3Q0S

Position
2p24.1
AA seq 1064 aa
MNHDFQALALESRGMGELLPTKKFWEPDDSTKDGQKGIFLGDDEWRETAWGASHHSMSQP
IMVQRRSGQGFHGNSEVNAILSPRSESGGLGVSMVEYVLSSSPADKLDSRFRKGNFGTRD
AETDGPEKGDQKGKASPFEEDQNRDLKQGDDDDSKINGRGLPNGMDADCKDFNRTPGSRQ
ASPTEVVERLGPNTNPSEGLGPLPNPTANKPLVEEFSNPETQNLDAMEQVGLESLQFDYP
GNQVPMDSSGATVGLFDYNSQQQLFQRTNALTVQQLTAAQQQQYALAAAQQPHIAGVFSA
GLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAATLAGPAVVPPQYYGVPWGVYPANLFQQ
QAAAAANNTASQQAASQAQPGQQQVLRAGAGQRPLTPNQGQQGQQAESLAAAAAANPTLA
FGQGLATGMPGYQVLAPTAYYDQTGALVVGPGARTGLGAPVRLMAPTPVLISSAAAQAAA
AAAAGGTASSLTGSTNGLFRPIGTQPPQQQQQQPSTNLQSNSFYGSSSLTNSSQSSSLFS
HGPGQPGSTSLGFGSGNSLGAAIGSALSGFGSSVGSSASSSATRRESLSTSSDLYKRSSS
SLAPIGQPFYNSLGFSSSPSPIGMPLPSQTPGHSLTPPPSLSSHGSSSSLHLGGLTNGSG
RYISAAPGAEAKYRSASSTSSLFSSSSQLFPPSRLRYNRSDIMPSGRSRLLEDFRNNRFP
NLQLRDLIGHIVEFSQDQHGSRFIQQKLERATPAERQMVFNEILQAAYQLMTDVFGNYVI
QKFFEFGSLDQKLALATRIRGHVLPLALQMYGCRVIQKALESISSDQQSEMVKELDGHVL
KCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFVLSTHPYGCRVIQRILEHCTAEQT
LPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVSEIRGKVLALSQHKFASNVV
EKCVTHASRAERALLIDEVCCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMH
KIRPHITTLRKYTYGKHILAKLEKYYLKNSPDLGPIGGPPNGML
NT seq 3195 nt   +upstreamnt  +downstreamnt
atgaatcatgattttcaagctcttgcattagaatctcggggaatgggagagcttttgcct
accaaaaagttttgggaacctgatgattcaacaaaagatggacaaaaaggcatatttctt
ggggatgatgaatggagagagactgcatggggagcttctcaccattcaatgtcccagcct
attatggtacagagaagatctggacagggttttcatggaaacagtgaagtaaatgcaata
ctgtctccgcgatcagaaagtggaggccttggtgtgagcatggtagaatatgtattaagt
tcttctcctgctgataaattggattctcgatttaggaagggaaattttggcactagagat
gctgaaacagatggacctgagaaaggagatcaaaaaggcaaggcttctccatttgaggag
gaccaaaacagagatcttaaacaaggagatgatgatgattctaaaataaatggcagaggt
ttgccaaatggaatggatgccgattgcaaagattttaatcgtactcctggaagtcgtcaa
gcctctccaactgaagtagttgagcgcttgggccccaatactaatccctcagaaggactg
gggcctcttcctaatcctacagctaataaaccacttgttgaagaattttcaaatcctgaa
actcagaatctggatgccatggaacaagttggtctggaatccttacagtttgactatcct
ggtaatcaggtaccaatggactcttcaggagctactgtaggcctttttgactacaattcc
cagcagcagctctttcagaggactaatgcactaacagttcaacagttaactgcagctcaa
cagcagcaatatgcattagcagcagctcagcagccacatatagctggtgtattctcagca
ggccttgctccagctgcatttgtgccaaatccatacattattagtgctgctcctccaggg
accgatccgtatactgcagcaggattggctgcagcagctacattagcaggtccagcagtg
gttccacctcagtattacggcgttccatggggggtgtatccagccaacttatttcagcag
caagctgcagctgcggcaaataacacagccagtcagcaagcagcatcacaagctcagcct
ggacagcaacaggttctccgtgctggagcaggtcagcgtcctcttactcccaatcagggt
cagcaagggcagcaagcagaatcacttgcggcagctgcagcagcaaatccaacattggct
tttggtcagggtcttgctactggcatgccaggctatcaagtactagctccaactgcctat
tatgatcagactggtgccttagtggttggccctggagcaaggactggccttggagctcca
gttcggttaatggctccaacacctgttttaattagttcagcagcagcacaagctgcagca
gcagcagcagctggaggaactgcaagtagccttacaggcagcacaaatggtctgtttcgg
ccaattggcactcagccaccacagcagcagcaacagcagccaagcactaatctgcaatct
aattcattttatggaagcagttctttgactaatagctcccagagtagttctttattttct
catggacctggtcaacctggaagtacatctcttggctttggaagtggtaactctttgggt
gctgctataggctcagccctcagtggatttggttcatcagttggcagttctgcaagtagt
agtgccacaaggagagagtctctatctactagctctgacttgtacaaaagatctagtagc
agcctagcacccatagggcaaccattttacaatagtctgggattttcctcctctccaagt
ccaataggcatgcctctgccaagccaaactccaggacattcacttacgccaccgccatca
ctttcatcacatggatcctcatccagtttgcatttaggaggactgacaaatggtagtggt
cgatatatctctgcagcacctggagcagaagcaaaatatcgaagtgcttcaagcacttcc
agtctatttagctccagcagccagctctttcctccttcccggcttcggtataataggtct
gatattatgccttctggccgcagtagattattggaagatttcagaaacaaccgcttccca
aaccttcagcttagagacttgattggacatatagttgagttttctcaagaccagcatggt
tctagattcatacagcaaaaactagagagagctactccagctgagcgacagatggtattt
aatgaaattctgcaagcagcctatcaattaatgactgatgtttttggcaactatgttata
cagaagttttttgagtttgggagtctggatcaaaaattagccctggctactcgtattcgt
ggtcatgttctacccttagccttgcagatgtatggctgccgcgttattcagaaagcatta
gaatctatttcttctgaccagcagagtgaaatggtaaaggagctggatggtcatgtgctc
aaatgtgtgaaagatcagaatggaaaccatgttgtacaaaaatgtatcgaatgtgttcag
ccacagtcactacagttcatcattgatgctttcaagggacaagtatttgtgctttcaact
catccttatggctgcagagtaattcagcgcatcctagagcattgcactgcagaacagacc
ttacctatcttagaagaactccaccaacatacagagcagttggtacaggatcagtatggc
aattatgttattcagcatgtactggaacacggtcgacctgaagacaagagcaaaattgtt
tccgaaatcaggggaaaggttttagccctgagtcaacacaaatttgccagcaatgtagta
gaaaagtgtgttactcatgcctcccgtgctgagagagctttactgattgacgaggtttgc
tgccagaatgatggtcctcacagtgccttatacaccatgatgaaggaccagtatgccaat
tacgtggttcaaaagatgattgatatggctgaacctgctcagagaaagataatcatgcac
aagattcgacctcacattactactttgcgcaaatacacatacgggaagcatatactggcc
aagttggaaaagtattatttgaagaatagcccggacctaggacctattggaggaccacca
aatggaatgctgtaa

KEGG   Homo sapiens (human): 9698
Entry
9698              CDS       T01001                                 

Gene name
PUM1, HSPUM, PUMH, PUMH1, PUML1, SCA47
Definition
(RefSeq) pumilio RNA binding family member 1
  KO
K17943  pumilio RNA-binding family
Organism
hsa  Homo sapiens (human)
Pathway
hsa05017  Spinocerebellar ataxia
Disease
H00063  Spinocerebellar ataxia (SCA)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    9698 (PUM1)
SSDB
Motif
Pfam: PUF DUF4821
Other DBs
NCBI-GeneID: 9698
NCBI-ProteinID: NP_055491
OMIM: 607204
HGNC: 14957
Ensembl: ENSG00000134644
Vega: OTTHUMG00000003795
Pharos: Q14671(Tbio)
UniProt: Q14671
LinkDB
Structure
PDB: 

Position
1p35.2
AA seq 1186 aa
MSVACVLKRKAVLWQDSFSPHLKHHPQEPANPNMPVVLTSGTGSQAQPQPAANQALAAGT
HSSPVPGSIGVAGRSQDDAMVDYFFQRQHGEQLGGGGSGGGGYNNSKHRWPTGDNIHAEH
QVRSMDELNHDFQALALEGRAMGEQLLPGKKFWETDESSKDGPKGIFLGDQWRDSAWGTS
DHSVSQPIMVQRRPGQSFHVNSEVNSVLSPRSESGGLGVSMVEYVLSSSPGDSCLRKGGF
GPRDADSDENDKGEKKNKGTFDGDKLGDLKEEGDVMDKTNGLPVQNGIDADVKDFSRTPG
NCQNSANEVDLLGPNQNGSEGLAQLTSTNGAKPVEDFSNMESQSVPLDPMEHVGMEPLQF
DYSGTQVPVDSAAATVGLFDYNSQQQLFQRPNALAVQQLTAAQQQQYALAAAHQPHIGLA
PAAFVPNPYIISAAPPGTDPYTAGLAAAATLGPAVVPHQYYGVTPWGVYPASLFQQQAAA
AAAATNSANQQTTPQAQQGQQQVLRGGASQRPLTPNQNQQGQQTDPLVAAAAVNSALAFG
QGLAAGMPGYPVLAPAAYYDQTGALVVNAGARNGLGAPVRLVAPAPVIISSSAAQAAVAA
AAASANGAAGGLAGTTNGPFRPLGTQQPQPQPQQQPNNNLASSSFYGNNSLNSNSQSSSL
FSQGSAQPANTSLGFGSSSSLGATLGSALGGFGTAVANSNTGSGSRRDSLTGSSDLYKRT
SSSLTPIGHSFYNGLSFSSSPGPVGMPLPSQGPGHSQTPPPSLSSHGSSSSLNLGGLTNG
SGRYISAAPGAEAKYRSASSASSLFSPSSTLFSSSRLRYGMSDVMPSGRSRLLEDFRNNR
YPNLQLREIAGHIMEFSQDQHGSRFIQLKLERATPAERQLVFNEILQAAYQLMVDVFGNY
VIQKFFEFGSLEQKLALAERIRGHVLSLALQMYGCRVIQKALEFIPSDQQNEMVRELDGH
VLKCVKDQNGNHVVQKCIECVQPQSLQFIIDAFKGQVFALSTHPYGCRVIQRILEHCLPD
QTLPILEELHQHTEQLVQDQYGNYVIQHVLEHGRPEDKSKIVAEIRGNVLVLSQHKFASN
VVEKCVTHASRTERAVLIDEVCTMNDGPHSALYTMMKDQYANYVVQKMIDVAEPGQRKIV
MHKIRPHIATLRKYTYGKHILAKLEKYYMKNGVDLGPICGPPNGII
NT seq 3561 nt   +upstreamnt  +downstreamnt
atgagcgttgcatgtgtcttgaagagaaaagcagtgctttggcaggactctttcagcccc
cacctgaaacatcaccctcaagaaccagctaatcccaacatgcctgttgttttgacatct
ggaacagggtcgcaagcgcagccacaaccagctgcaaatcaggctcttgcagctgggact
cactccagccctgtcccaggatctataggagttgcaggccgttcccaggacgacgctatg
gtggactacttctttcagaggcagcatggtgagcagcttgggggaggaggaagtggagga
ggcggctataataatagcaaacatcgatggcctactggggataacattcatgcagaacat
caggtgcgttccatggatgaactgaatcatgattttcaagcacttgctctggagggaaga
gcgatgggagagcagctcttgccaggtaaaaagttttgggaaacagatgaatccagcaaa
gatggaccaaaaggaatattcctgggtgatcaatggcgagacagtgcctggggaacatca
gatcattcagtttcccagccaatcatggtgcagagaagacctggtcagagtttccatgtg
aacagtgaggtcaattctgtactgtccccacgatcggagagtgggggactaggcgttagc
atggtggagtatgtgttgagctcatccccgggcgattcctgtctaagaaaaggaggattt
ggcccaagggatgcagacagtgatgaaaacgacaaaggtgaaaagaagaacaagggtacg
tttgatggagataagctaggagatttgaaggaggagggtgatgtgatggacaagaccaat
ggtttaccagtgcagaatgggattgatgcagacgtcaaagattttagccgtacccctggt
aattgccagaactctgctaatgaagtggatcttctgggtccaaaccagaatggttctgag
ggcttagcccagctgaccagcaccaatggtgccaagcctgtggaggatttctccaacatg
gagtcccagagtgtccccttggaccccatggaacatgtgggcatggagcctcttcagttt
gattattcaggcacgcaggtacctgtggactcagcagcagcaactgtgggactttttgac
tacaattctcaacaacagctgttccaaagacctaatgcgcttgctgtccagcagttgaca
gctgctcagcagcagcagtatgcactggcagctgctcatcagccgcacatcggtttagct
cccgctgcgtttgtccccaatccatacatcatcagcgctgctcccccagggacggacccc
tacacagctggattggctgcagcagcgacactaggcccagctgtggtccctcaccagtat
tatggagttactccctggggagtctaccctgccagtcttttccagcagcaagctgccgct
gccgctgcagcaactaattcagctaatcaacagaccaccccacaggctcagcaaggacag
cagcaggttctccgtggaggagccagccaacgtcctttgaccccaaaccagaaccagcag
ggacagcaaacggatccccttgtggcagctgcagcagtgaattctgcccttgcatttgga
caaggtctggcagcaggcatgccaggttatccggtgttggctcctgctgcttactatgac
caaactggtgcccttgtagtgaatgcaggcgcgagaaatggtcttggagctcctgttcga
cttgtagctcctgccccagtcatcattagttcctcagctgcacaagcagctgttgcagca
gccgcagcttcagcaaatggagcagctggtggtcttgctggaacaacaaatggaccattt
cgccctttaggaacacagcagcctcagccccagccccagcagcagcccaataacaacctg
gcatccagttctttctacggcaacaactctctgaacagcaattcacagagcagctccctc
ttctcccagggctctgcccagcctgccaacacatccttgggattcggaagtagcagttct
ctcggcgccaccctgggatccgcccttggagggtttggaacagcagttgcaaactccaac
actggcagtggctcccgccgtgactccctgactggcagcagtgacctttataagaggaca
tcgagcagcttgacccccattggacacagtttttataacggccttagcttttcctcctct
cctggacccgtgggcatgcctctccctagtcagggaccaggacattcacagacaccacct
ccttccctctcttcacatggatcctcttcaagcttaaacctgggaggactcacgaatggc
agtggaagatacatctctgctgctccaggcgctgaagccaagtaccgcagtgcaagcagc
gcctccagcctcttcagcccgagcagcactcttttctcttcctctcgtttgcgatatgga
atgtctgatgtcatgccttctggcaggagcaggcttttggaagattttcgaaacaaccgg
taccccaatttacaactgcgggagattgctggacatataatggaattttcccaagaccag
catgggtccagattcattcagctgaaactggagcgtgccacaccagctgagcgccagctt
gtcttcaatgaaatcctccaggctgcctaccaactcatggtggatgtgtttggtaattac
gtcattcagaagttctttgaatttggcagtcttgaacagaagctggctttggcagaacgg
attcgaggccacgtcctgtcattggcactacagatgtatggctgccgtgttatccagaaa
gctcttgagtttattccttcagaccagcagaatgagatggttcgggaactagatggccat
gtcttgaagtgtgtgaaagatcagaatggcaatcacgtggttcagaaatgcattgaatgt
gtacagccccagtctttgcaatttatcatcgatgcgtttaagggacaggtatttgcctta
tccacacatccttatggctgccgagtgattcagagaatcctggagcactgtctccctgac
cagacactccctattttagaggagcttcaccagcacacagagcagcttgtacaggatcaa
tatggaaattatgtaatccaacatgtactggagcacggtcgtcctgaggataaaagcaaa
attgtagcagaaatccgaggcaatgtacttgtattgagtcagcacaaatttgcaagcaat
gttgtggagaagtgtgttactcacgcctcacgtacggagcgcgctgtgctcatcgatgag
gtgtgcaccatgaacgacggtccccacagtgccttatacaccatgatgaaggaccagtat
gccaactacgtggtccagaagatgattgacgtggcggagccaggccagcggaagatcgtc
atgcataagatccggccccacatcgcaactcttcgtaagtacacctatggcaagcacatt
ctggccaagctggagaagtactacatgaagaacggtgttgacttagggcccatctgtggc
ccccctaatggtatcatctga

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