Homo sapiens (human): 23395
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Entry
23395 CDS
T01001
Symbol
LARS2, HLASA, LEURS, PRLTS4, mtLeuRS
Name
(RefSeq) leucyl-tRNA synthetase 2, mitochondrial
KO
K01869
leucyl-tRNA synthetase [EC:
6.1.1.4
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00970
Aminoacyl-tRNA biosynthesis
Disease
H02095
Perrault syndrome
H02841
Hydrops, lactic acidosis, and sideroblastic anemia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
00970 Aminoacyl-tRNA biosynthesis
23395 (LARS2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01007 Amino acid related enzymes [BR:
hsa01007
]
23395 (LARS2)
09182 Protein families: genetic information processing
03016 Transfer RNA biogenesis [BR:
hsa03016
]
23395 (LARS2)
03029 Mitochondrial biogenesis [BR:
hsa03029
]
23395 (LARS2)
Enzymes [BR:
hsa01000
]
6. Ligases
6.1 Forming carbon-oxygen bonds
6.1.1 Ligases forming aminoacyl-tRNA and related compounds
6.1.1.4 leucine---tRNA ligase
23395 (LARS2)
Amino acid related enzymes [BR:
hsa01007
]
Aminoacyl-tRNA synthetase
Class I (U)
23395 (LARS2)
Transfer RNA biogenesis [BR:
hsa03016
]
Eukaryotic type
Aminoacyl-tRNA synthetases (AARSs)
Multi-aminoacyl-tRNA synthetase complex (MSC)
23395 (LARS2)
Prokaryotic type
23395 (LARS2)
Mitochondrial biogenesis [BR:
hsa03029
]
Mitochondrial DNA transcription, translation, and replication factors
Mitochondrial transcription and translation factors
Other mitochondrial DNA transcription and translation factors
23395 (LARS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
tRNA-synt_1
tRNA-synt_1g
Anticodon_1
tRNA-synt_1_2
tRNA-synt_1f
Motif
Other DBs
NCBI-GeneID:
23395
NCBI-ProteinID:
NP_001355192
OMIM:
604544
HGNC:
17095
Ensembl:
ENSG00000011376
UniProt:
Q15031
LinkDB
All DBs
Position
3:45388576..45549407
Genome browser
AA seq
903 aa
AA seq
DB search
MASVWQRLGFYASLLKRQLNGGPDVIKWERRVIPGCTRSIYSATGKWTKEYTLQTRKDVE
KWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRGM
QVINPMGWDAFGLPAENAAVERNLHPQSWTQSNIKHMRKQLDRLGLCFSWDREITTCLPD
YYKWTQYLFIKLYEAGLAYQKEALVNWDPVDQTVLANEQVDEHGCSWRSGAKVEQKYLRQ
WFIKTTAYAKAMQDALADLPEWYGIKGMQAHWIGDCVGCHLDFTLKVHGQATGEKLTAYT
ATPEAIYGTSHVAISPSHRLLHGHSSLKEALRMALVPGKDCLTPVMAVNMLTQQEVPVVI
LAKADLEGSLDSKIGIPSTSSEDTILAQTLGLAYSEVIETLPDGTERLSSSAEFTGMTRQ
DAFLALTQKARGKRVGGDVTSDKLKDWLISRQRYWGTPIPIVHCPVCGPTPVPLEDLPVT
LPNIASFTGKGGPPLAMASEWVNCSCPRCKGAAKRETDTMDTFVDSAWYYFRYTDPHNPH
SPFNTAVADYWMPVDLYIGGKEHAVMHLFYARFFSHFCHDQKMVKHREPFHKLLAQGLIK
GQTFRLPSGQYLQREEVDLTGSVPVHAKTKEKLEVTWEKMSKSKHNGVDPEEVVEQYGID
TIRLYILFAAPPEKDILWDVKTDALPGVLRWQQRLWTLTTRFIEARASGKSPQPQLLSNK
EKAEARKLWEYKNSVISQVTTHFTEDFSLNSAISQLMGLSNALSQASQSVILHSPEFEDA
LCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQ
MAVLINNKACGKIPVPQQVARDQDKVHEFVLQSELGVRLLQGRSIKKSFLSPRTALINFL
VQD
NT seq
2712 nt
NT seq
+upstream
nt +downstream
nt
atggcttctgtttggcagagattgggtttttatgcctctcttctgaaaagacagctaaat
ggtgggccagatgtcatcaagtgggaaaggagagtaattcccggatgtaccagaagcatc
tacagtgccacgggaaagtggacaaaagagtatacattgcagacaagaaaggatgttgag
aaatggtggcatcaacgaataaaagaacaggcctccaaaatttcagaagctgataaatcg
aagccaaaattttacgtgctttccatgttcccttatccttctggtaagctgcacatgggc
catgtgcgtgtctacaccatcagcgacaccatagcacggttccagaagatgagagggatg
caggtcatcaaccccatgggatgggatgcttttggattgcctgctgaaaatgccgcagtc
gagaggaatctacatccacaaagttggacacaaagtaatattaaacacatgaggaaacag
cttgatcgtctgggcctgtgtttcagctgggatagggaaataactacgtgtttgccagat
tactacaagtggactcagtatctctttattaaactgtatgaggctgggctggcctatcaa
aaggaggccctggttaactgggacccagtggatcaaacagtgcttgccaatgagcaggtg
gatgaacatggctgttcatggcgttctggagcaaaggtggaacagaagtacctcagacaa
tggtttattaagacaaccgcttatgcaaaggccatgcaggacgcgttggcagaccttcca
gaatggtatggaataaaaggcatgcaagcccactggattggggactgtgtgggctgccac
ctggacttcacattaaaggttcatgggcaagccacgggcgaaaagctgactgcctatacg
gccacccctgaagccatttatggcacctcccacgtggccatctcgcccagccacagactc
ctacatgggcacagctctctgaaggaagccttgaggatggcccttgtccctggcaaagat
tgcctcacgcctgtaatggctgtgaacatgcttacccagcaggaggtccctgtcgttatt
ttggccaaagctgacttggaaggctctctggattcaaaaataggaattcccagtactagc
tcagaggacaccatcttagcccaaaccctgggcctggcctactctgaagtcattgaaact
ttgccagatggcacagagagactgagcagctctgctgagttcacaggtatgacccggcag
gatgcttttctagccctgactcagaaagcccgggggaagagagtgggtggagacgtgaca
agtgataaactgaaagactggctgatttcacggcagcggtactggggcacaccaatcccc
attgtccactgcccagtctgtggccccacacctgtgcccctggaggacttgcctgtgacc
ctgcccaacatcgcgtctttcactggcaagggaggccccccactggccatggcttcagag
tgggtgaactgctcctgcccaaggtgcaagggagcagccaagagagagacagacacgatg
gatacctttgttgattctgcttggtactacttcagatacactgaccctcataatccacac
agcccttttaacacagcagtggccgattactggatgcctgtggatttgtacattggaggg
aaagaacatgccgtcatgcacttgttctatgcaagattctttagtcatttttgccatgat
caaaaaatggttaaacatagggagccttttcataagctgctggcccaaggccttatcaag
gggcagacattccgcctaccatctggacagtatctacagagagaggaagtggatctcaca
ggttccgttcctgttcatgcaaaaacgaaagagaagttagaggtgacgtgggagaagatg
agtaagtccaaacacaacggggtggacccagaggaagttgtggagcagtatgggatcgac
acgattcggctctacatcctttttgctgcccctcctgagaaggatatcttgtgggatgtg
aaaactgatgctctccctggggtgctgagatggcaacaacgactgtggaccttgacaact
cggtttattgaggccagggcttctgggaagtctccccagcctcagctgctgagtaacaag
gagaaagctgaggccaggaagctctgggagtacaagaactccgtcatctctcaggtgacc
acccatttcacagaggacttctcactgaattctgcaatttctcagctgatgggactcagc
aatgccctctcgcaagcctctcagagcgtcattctccacagccccgagtttgaggatgct
ttgtgtgccctgatggtaatggctgctccactggcccctcatgtaacctcagagatctgg
gcaggcctggcgctggtgccgaggaagctctgtgcccactacacttgggatgccagtgtg
ctgctccaggcatggcctgctgtggacccggagttcctgcagcagcctgaggttgtccag
atggcagttctgatcaacaataaagcttgtggcaaaattcctgtgccccaacaagttgcc
cgggaccaggacaaagtccacgaatttgttcttcaaagcgagctgggtgtcaggcttttg
caaggacgaagcatcaagaagtccttcctttccccgagaactgccctcatcaacttcctg
gtgcaagattga
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