Homo sapiens (human): 259232
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Entry
259232 CDS
T01001
Symbol
NALCN, CLIFAHDD, CanIon, IHPRF, IHPRF1, INNFD, VGCNL1, bA430M15.1
Name
(RefSeq) sodium leak channel, non-selective
KO
K21863
sodium leak channel non-selective protein
Organism
hsa
Homo sapiens (human)
Disease
H01922
Infantile hypotonia with psychomotor retardation and characteristic facies
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
259232 (NALCN)
Ion channels [BR:
hsa04040
]
Voltage-gated cation channels
Sodium leak channel, non-selective
259232 (NALCN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
PKD_channel
PsaF
DUF5914
FAM165
Motif
Other DBs
NCBI-GeneID:
259232
NCBI-ProteinID:
NP_001337678
OMIM:
611549
HGNC:
19082
Ensembl:
ENSG00000102452
UniProt:
Q8IZF0
Structure
PDB
PDBj
LinkDB
All DBs
Position
13:complement(101053776..101417179)
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AA seq
1738 aa
AA seq
DB search
MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPMT
FEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWV
SLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWS
VSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCP
PGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYF
YFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQ
LVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYL
AEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVL
RVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTF
PRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILD
NLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRE
SFMKQFIDRQQQDTCCLLRSLPTTSSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLL
EKETAVTKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQERRSLRHGSNSQRISRGK
SLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIV
GREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIIVTICSC
ISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIF
IYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLV
SILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEK
KPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFV
FLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFR
AKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVPLATMSVVFTFIFVLEVTMKI
IAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVT
LKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAIT
VLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLN
LLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGR
LEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLE
YTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELSRFLNPPSIETTQPS
EDTNANSQDNSMQPETSSQQQLLSPTLSDRGGSRQDAADAGKPQRKFGQWRLPSAPKPIS
HSVSSVNLRFGGRTTMKSVVCKMNPMTDAASCGSEVKKWWTRQLTVESDESGDDLLDI
NT seq
5217 nt
NT seq
+upstream
nt +downstream
nt
atgctcaaaaggaagcagagttccagggtggaagcccagccagtcactgactttggtcct
gatgagtctctgtcggataatgctgacatcctctggattaacaaaccatgggttcactct
ttgctgcgcatctgtgccatcatcagcgtcatttctgtttgtatgaatacgccaatgacc
ttcgagcactatcctccacttcagtatgtgaccttcactttggatacattattgatgttt
ctctacacggcagagatgatagcaaaaatgcacatccggggcattgtcaagggggatagt
tcctatgtgaaagatcgctggtgtgtttttgatggatttatggtcttttgcctttgggtt
tctttggtgctacaggtgtttgaaattgctgatatagttgatcagatgtcaccttggggc
atgttgcggattccacggccactgattatgatccgagcattccggatttatttccgattt
gaactgccaaggaccagaattacaaatattttaaagcgatcgggagaacaaatatggagt
gtttccatttttctacttttctttctacttctttatggaattttaggagttcagatgttt
ggaacatttacttatcactgtgttgtaaatgacacaaagccagggaatgtaacctggaat
agtttagctattccagacacacactgctcaccagagctagaagaaggctaccagtgccca
cctggatttaaatgcatggaccttgaagatctgggacttagcaggcaagagctgggctac
agtggctttaatgagataggaactagtatattcaccgtctatgaggccgcctcacaggaa
ggctgggtgttcctcatgtacagagcaattgacagctttccccgttggcgttcctacttc
tatttcatcactctcattttcttcctcgcctggcttgtgaagaacgtgtttattgctgtt
atcattgaaacatttgcagaaatcagagtacagtttcaacaaatgtggggatcgagaagc
agcactacctcaacagccaccacccagatgtttcatgaagatgctgctggaggttggcag
ctggtagctgtggatgtcaacaagccccagggacgcgccccagcctgcctccagaaaatg
atgcggtcatccgttttccacatgttcatcctgagcatggtgaccgtggacgtgatcgtg
gcggctagcaactactacaaaggagaaaacttcaggaggcagtacgacgagttctacctg
gcggaggtggcttttacagtactttttgatttggaagcacttctgaagatatggtgtttg
ggatttactggatatattagctcatctctccacaaattcgaactactactcgtaattgga
actactcttcatgtatacccagatctttatcattcacaattcacgtactttcaggttctc
cgagtagttcggctgattaagatttcacctgcattagaagactttgtgtacaagatattt
ggtcctggaaaaaagcttgggagtttggttgtatttactgccagcctcttgattgttatg
tcagcaattagtttgcagatgttctgctttgtcgaagaactggacagatttactacgttt
ccgagggcatttatgtccatgttccagatcctcacccaggaaggatgggtggacgtaatg
gaccaaactctaaatgctgtgggacatatgtgggcacccgtggttgccatctatttcatt
ctctatcatctttttgccactctgatcctcctgagtttgtttgttgctgttattttggac
aacttagaacttgatgaagacctaaagaagcttaaacaattaaagcaaagtgaagcaaat
gcggacaccaaagaaaagctccctttacgcctgcgaatctttgaaaaatttccaaacaga
cctcaaatggtgaaaatctcaaagcttccttcagattttacagttcctaaaatcagggag
agttttatgaagcagtttattgaccgccagcaacaggacacatgttgcctcctgagaagc
ctcccgaccacctcttcctcctcctgcgaccactccaaacgctcagcaattgaggacaac
aaatacatcgaccaaaaacttcgcaagtctgttttcagcatcagggcaaggaaccttctg
gaaaaggagaccgcagtcactaaaatcttaagagcttgcacccgacagcgcatgctgagc
ggatcatttgaggggcagcccgcaaaggagaggtcaatcctcagcgtgcagcatcatatc
cgccaagagcgcaggtcactaagacatggatcaaacagccagaggatcagcaggggaaaa
tctcttgaaactttgactcaagatcattccaatacagtgagatatagaaatgcacaaaga
gaagacagtgaaataaagatgattcaggaaaaaaaggagcaagcagagatgaaaaggaaa
gtgcaagaagaggaactcagagagaaccacccatacttcgataagccactgttcattgtc
gggcgagaacacaggttcagaaacttttgccgggtggtggtccgagcacgcttcaacgca
tctaaaacagaccctgtcacaggagctgtgaaaaatacaaagtaccatcaactttatgat
ttgctgggattggtcacttacctggactgggtcatgatcatcgtaaccatctgctcttgc
atttccatgatgtttgagtccccgtttcgaagagtcatgcatgcacctactttgcagatt
gctgagtatgtgtttgtgatattcatgagcattgagcttaatctgaagattatggcagat
ggcttatttttcactccaactgctgtcatcagggacttcggtggagtaatggacatattt
atatatcttgtgagcttgatatttctttgttggatgcctcaaaatgtacctgctgaatcg
ggagctcagcttctaatggtccttcggtgcctgagacctctgcgcatattcaaactggtg
ccccagatgaggaaagttgttcgagaacttttcagcggcttcaaggaaatttttttggtc
tccattcttttgctgacattaatgctcgtttttgcaagctttggagttcagctttttgct
ggaaaactggccaagtgcaatgatcccaacattattagaagggaagattgcaatggcata
ttcagaattaatgtcagtgtgtcaaagaacttaaatttaaaattgaggcctggagagaaa
aaacctggattttgggtgccccgtgtttgggcgaatcctcggaactttaatttcgacaat
gtgggaaacgctatgctggcgttgtttgaagttctctccttgaaaggctgggtggaagtg
agagatgttattattcatcgtgtggggccgatccatggaatctatattcatgtttttgta
ttcctgggttgcatgattggactgaccctttttgttggagtagttattgctaatttcaat
gaaaacaaggggacggctttgctgaccgtcgatcagagaagatgggaagacctgaagagc
cgactgaagatcgcacagcctcttcatcttccgcctcgcccggataatgatggttttaga
gctaaaatgtatgacataacccagcatccattttttaagaggacaatcgcattactcgtc
ctggcccagtcggtgttgctctctgtcaagtgggacgtcgaggacccggtgaccgtacct
ttggcaacaatgtcagttgttttcaccttcatctttgttctggaggttaccatgaagatc
atagcaatgtcgcctgctggcttctggcaaagcagaagaaaccgatacgatctcctggtg
acgtcgcttggcgttgtatgggtggtgcttcactttgccctcctgaatgcatatacttac
atgatgggcgcttgtgtgattgtatttaggtttttctccatctgtggaaaacatgtaacg
ctaaagatgctcctcttgacagtggtcgtcagcatgtacaagagcttctttatcatagta
ggcatgtttctcttgctgctgtgttacgcttttgctggagttgttttatttggtactgtg
aaatatggggagaatattaacaggcatgcaaatttttcttcggctggaaaagctattacc
gtactgttccgaattgtcacaggtgaagactggaacaagattatgcatgactgtatggtt
cagcctccgttttgtactccagatgaatttacatactgggcaacagactgtggaaattat
gctggggcacttatgtatttctgttcattttatgtcatcattgcctacatcatgctaaat
ctgcttgtagccataattgtggagaatttctccttgttttattccactgaggaggaccag
cttttaagttacaatgatcttcgccactttcaaataatatggaacatggtggatgataaa
agagagggggtgatccccacgttccgcgtcaagttcctgctgcggctactgcgtgggagg
ctggaggtggacctggacaaggacaagctcctgtttaagcacatgtgctacgaaatggag
aggctccacaatggcggcgacgtcaccttccatgatgtcctgagcatgctttcataccgg
tccgtggacatccggaagagcttgcagctggaggaactcctggcgagggagcagctggag
tacaccatagaggaggaggtggccaagcagaccatccgcatgtggctcaagaagtgcctg
aagcgcatcagagctaaacagcagcagtcgtgcagtatcatccacagcctgagagagagt
cagcagcaagagctgagccggtttctgaacccgcccagcatcgagaccacccagcccagt
gaggacacgaatgccaacagtcaggacaacagcatgcaacctgagacaagcagccagcag
cagctcctgagccccacgctgtcggatcgaggaggaagtcggcaagatgcagccgacgca
gggaaaccccagaggaaatttgggcagtggcgtctgccctcagccccaaaaccaataagc
cattcagtgtcctcagtcaacttacggtttggaggaaggacaaccatgaaatctgtcgtg
tgcaaaatgaaccccatgactgacgcggcttcctgcggttctgaagttaagaagtggtgg
acccggcagctgactgtggagagcgacgaaagtggggatgaccttctggatatttag
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integrated database retrieval system
