Homo sapiens (human): 2615
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Entry
2615 CDS
T01001
Symbol
LRRC32, CPPRDD, D11S833E, GARP
Name
(RefSeq) leucine rich repeat containing 32
KO
K26316
transforming growth factor beta activator LRRC32
Organism
hsa
Homo sapiens (human)
Pathway
hsa04350
TGF-beta signaling pathway
Disease
H02535
Neurodevelopmental disorder with dysmorphic facies
Drug target
Livmoniplimab:
D12793
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
2615 (LRRC32)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
LRR_8
LRR_4
LRR_1
LRR_5
LRRNT
LRR_9
Motif
Other DBs
NCBI-GeneID:
2615
NCBI-ProteinID:
NP_001122394
OMIM:
137207
HGNC:
4161
Ensembl:
ENSG00000137507
UniProt:
Q14392
Structure
PDB
LinkDB
All DBs
Position
11:complement(76657524..76670747)
Genome browser
AA seq
662 aa
AA seq
DB search
MRPQILLLLALLTLGLAAQHQDKVPCKMVDKKVSCQVLGLLQVPSVLPPDTETLDLSGNQ
LRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGL
GPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDL
HSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLRVLDLSCNSIEAFQTASQPQ
AEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWSAL
PLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLG
SLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGN
RVSPCGGPDEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLE
VATGALGGLEASLEVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSHLPAWTQAVSLEV
LDLRNNSFSLLPGSAMGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLIC
RFSSQEEVSLSHVRPEDCEKGGLKNINLIIILTFILVSAILLTTLAACCCVRRQKFNQQY
KA
NT seq
1989 nt
NT seq
+upstream
nt +downstream
nt
atgagaccccagatcctgctgctcctggccctgctgaccctaggcctggctgcacaacac
caagacaaagtgccctgtaagatggtggacaagaaggtctcgtgccaggttctgggcctg
ctccaggtcccctcggtgctcccgccagacactgagacccttgatctatctgggaaccag
ctgcggagtatcctggcctcacccctgggcttctacacagcacttcgtcacctggacctg
agcaccaatgagatcagcttcctccagccaggagccttccaggccctgacccacctggag
cacctcagcctggctcacaaccggctggcgatggccactgcgctgagtgctggtggcctg
ggccccctgccacgcgtgacctccctggacctgtctgggaacagcctgtacagcggcctg
ctggagcggctgctgggggaggcacccagcctgcataccctctcactggcggagaacagt
ctgactcgcctcacccgccacaccttccgggacatgcctgcgctggagcagcttgacctg
catagcaacgtgctgatggacatcgaggatggcgccttcgagggtctgccccgcctgacc
catctcaacctctccaggaattccctcacctgcatctccgacttcagcctccagcagctg
cgggtgctagacctgagctgcaacagcatcgaggcctttcagacggcctcccagccccag
gctgagttccagctcacctggcttgacctgcgggagaacaaactgctccatttccccgac
ctggccgcgctcccgagactcatctacctgaacttgtccaacaacctcatccggctcccc
acagggccaccccaggacagcaagggcatccacgcaccttccgagggctggtcagccctg
cccctctcagcccccagcgggaatgccagcggccgccccctttcccagctcttgaatctg
gatttgagctacaatgagattgagctcatccccgacagctttcttgagcacctgacctcc
ctgtgcttcctgaacctcagcagaaactgcttgcggacctttgaggcccggcgcttaggc
tccctgccctgcctgatgctccttgacttaagccacaatgccctggagacactggaactg
ggcgccagagccctggggtctctgcggacgctgctcctacagggcaatgccctgcgggac
ctgcccccatacacctttgccaatctggccagcctgcagcggctcaacctgcaggggaac
cgagtcagcccctgtggggggccagatgagcctggcccctccggctgtgtggccttctcc
ggcatcacctccctccgcagcctgagcctggtggataatgagatagagctgctcagggca
ggggccttcctccacaccccactgactgagctggacctttcttccaatcctgggctggag
gtggccacgggggccttgggaggcctggaggcctccttggaggtcctggcactgcagggc
aacgggctgatggtcctgcaggtggacctgccctgcttcatctgcctcaagcggctcaat
cttgccgagaaccgcctgagccaccttcccgcctggacacaggctgtgtcactggaggtg
ctggacctgcgaaacaacagcttcagcctcctgccaggcagtgccatgggtggcctggag
accagcctccggcgcctctacctgcaggggaatccactcagctgctgcggcaatggctgg
ctggcagcccagctgcaccagggccgtgtggacgtggacgccacccaggacctgatctgc
cgcttcagctcccaggaggaggtgtccctgagccacgtgcgtcccgaggactgtgagaag
gggggactgaagaacatcaacctcatcatcatcctcaccttcatactggtctctgccatc
ctcctcaccacgctggccgcctgctgctgcgtccgccggcagaagtttaaccaacagtat
aaagcctaa
Homo sapiens (human): 375387
Help
Entry
375387 CDS
T01001
Symbol
NRROS, ELLP3030, GARPL1, LRRC33, SENEBAC, UNQ3030
Name
(RefSeq) negative regulator of reactive oxygen species
KO
K26317
transforming growth factor beta activator LRRC33
Organism
hsa
Homo sapiens (human)
Pathway
hsa04350
TGF-beta signaling pathway
Disease
H02770
Early-onset seizures with neurodegeneration and brain calcifications
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
375387 (NRROS)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
LRR_8
LRR_4
LRR_1
LRR_6
LRR_9
Motif
Other DBs
NCBI-GeneID:
375387
NCBI-ProteinID:
NP_940967
OMIM:
615322
HGNC:
24613
Ensembl:
ENSG00000174004
UniProt:
Q86YC3
LinkDB
All DBs
Position
3:196639694..196662004
Genome browser
AA seq
692 aa
AA seq
DB search
MELLPLWLCLGFHFLTVGWRNRSGTATAASQGVCKLVGGAADCRGQSLASVPSSLPPHAR
MLTLDANPLKTLWNHSLQPYPLLESLSLHSCHLERISRGAFQEQGHLRSLVLGDNCLSEN
YEETAAALHALPGLRRLDLSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEGL
ERLRELDLQRNYIFEIEGGAFDGLAELRHLNLAFNNLPCIVDFGLTRLRVLNVSYNVLEW
FLATGGEAAFELETLDLSHNQLLFFPLLPQYSKLRTLLLRDNNMGFYRDLYNTSSPREMV
AQFLLVDGNVTNITTVSLWEEFSSSDLADLRFLDMSQNQFQYLPDGFLRKMPSLSHLNLH
QNCLMTLHIREHEPPGALTELDLSHNQLSELHLAPGLASCLGSLRLFNLSSNQLLGVPPG
LFANARNITTLDMSHNQISLCPLPAASDRVGPPSCVDFRNMASLRSLSLEGCGLGALPDC
PFQGTSLTYLDLSSNWGVLNGSLAPLQDVAPMLQVLSLRNMGLHSSFMALDFSGFGNLRD
LDLSGNCLTTFPRFGGSLALETLDLRRNSLTALPQKAVSEQLSRGLRTIYLSQNPYDCCG
VDGWGALQHGQTVADWAMVTCNLSSKIIRVTELPGGVPRDCKWERLDLGLLYLVLILPSC
LTLLVACTVIVLTFKKPLLQVIKSRCHWSSVY
NT seq
2079 nt
NT seq
+upstream
nt +downstream
nt
atggagttgctgcctctttggctctgcctgggttttcacttcctgaccgtgggctggagg
aacagaagcggaacagccacagcagcctcccaaggagtctgcaagttggtgggtggagcc
gctgactgccgagggcagagcctcgcttcggtgcccagcagcctcccgccccacgcccgg
atgctcaccctggatgccaaccctctcaagaccctgtggaatcactccctccagccttac
cctctcctggagagcctcagcctgcacagctgccacctggagcgcatcagccgcggcgcc
ttccaggagcaaggtcacctgcgcagcctggtcctgggggacaactgcctctcagagaac
tacgaagagacggcagccgccctccacgccctgccgggcctgcggaggctggacttgtca
ggaaacgccctgacggaggacatggcagccctcatgctccagaacctctcctcgctgcgg
tccgtgtccctggcggggaacaccatcatgcggctggacgactccgtcttcgagggcctg
gagcgtctccgggagctggatctgcagaggaactacatcttcgagatcgagggcggcgct
ttcgacggcctggctgagctgaggcacctcaacctggccttcaacaacctcccctgcatc
gtggacttcgggctcacgcggctgcgggtcctcaacgtcagctacaacgtcctggagtgg
ttcctcgcgaccgggggagaggctgccttcgagctggagacgctggacctgtctcacaac
cagctgctgttcttcccgctgctgccccagtacagcaagttgcggaccctcctgctgcgc
gacaacaacatgggcttctaccgggacctgtacaacacctcgtcgccgagggagatggtg
gcccagttcctcctcgtggacggcaacgtgaccaacatcaccaccgtcagcctctgggaa
gaattctcctccagcgacctcgcagatctccgcttcctggacatgagccagaaccagttc
cagtacctgccagacggcttcctgaggaaaatgccttccctctcccacctgaacctccac
cagaattgcctgatgacgcttcacattcgggagcacgagccccccggagcgctcaccgag
ctggacctgagccacaaccagctgtcggagctgcacctggctccggggctggccagctgc
ctgggcagcctgcgcttgttcaacctgagctccaaccagctcctgggcgtcccccctggc
ctcttcgccaatgctaggaacatcactacacttgacatgagccacaatcagatctcactt
tgtcccctgccagctgcctcggaccgggtgggcccccctagctgtgtggatttcaggaat
atggcatctttaaggagcctgtctctggagggctgtggcctgggggcattgccagactgc
ccattccaagggacctccctgacctacttagacctctcaagcaactggggggttctgaat
gggagcctcgccccactccaggatgttgcccccatgttacaggtcctgtctctcaggaac
atgggcctccactccagctttatggcgttggacttctctgggtttgggaatctcagggac
ttagatctgtcggggaattgcttgaccaccttcccaaggtttgggggcagcctggccctg
gagaccctggatctccgtagaaactcgctcacagcccttccccagaaggctgtgtctgag
cagctctcgagaggtctgcggaccatctacctcagtcagaatccatatgactgctgtggg
gtggatggctggggggccctgcagcatgggcagacggtggccgactgggccatggtcacc
tgcaacctctcctccaagatcatccgcgtgacggagctgcccggaggtgtgcctcgggac
tgcaagtgggagcggctggacctgggcctgctctacctcgtgctcatcctccccagctgc
ctcaccctgctggtggcctgcactgtcatcgtcctcacttttaagaagcctctgcttcag
gtcatcaagagccgctgccactggtcctccgtttactga
DBGET
integrated database retrieval system
