KEGG   Homo sapiens (human): 26585
Entry
26585             CDS       T01001                                 
Symbol
GREM1, C15DUPq, CKTSF1B1, CRAC1, CRCS4, DAND2, DRM, DUP15q, GREMLIN, HMPS, HMPS1, IHG-2, MPSH, PIG2
Name
(RefSeq) gremlin 1, DAN family BMP antagonist
  KO
K23318  gremlin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04350  TGF-beta signaling pathway
Network
nt06507  TGFB signaling
  Element
N01428  BMP signaling pathway, BMP antagonist
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    26585 (GREM1)
SSDB
Motif
Pfam: DAN
Other DBs
NCBI-GeneID: 26585
NCBI-ProteinID: NP_037504
OMIM: 603054
HGNC: 2001
Ensembl: ENSG00000166923
UniProt: O60565 A6XAA7
Structure
LinkDB
Position
15:32718004..32745106
AA seq 184 aa
MSRTAYTVGALLLLLGTLLPAAEGKKKGSQGAIPPPDKAQHNDSEQTQSPQQPGSRNRGR
GQGRGTAMPGEEVLESSQEALHVTERKYLKRDWCKTQPLKQTIHEEGCNSRTIINRFCYG
QCNSFYIPRHIRKEEGSFQSCSFCKPKKFTTMMVTLNCPELQPPTKKKRVTRVKQCRCIS
IDLD
NT seq 555 nt   +upstreamnt  +downstreamnt
atgagccgcacagcctacacggtgggagccctgcttctcctcttggggaccctgctgccg
gctgctgaagggaaaaagaaagggtcccaaggtgccatccccccgccagacaaggcccag
cacaatgactcagagcagactcagtcgccccagcagcctggctccaggaaccgggggcgg
ggccaagggcggggcactgccatgcccggggaggaggtgctggagtccagccaagaggcc
ctgcatgtgacggagcgcaaatacctgaagcgagactggtgcaaaacccagccgcttaag
cagaccatccacgaggaaggctgcaacagtcgcaccatcatcaaccgcttctgttacggc
cagtgcaactctttctacatccccaggcacatccggaaggaggaaggttcctttcagtcc
tgctccttctgcaagcccaagaaattcactaccatgatggtcacactcaactgccctgaa
ctacagccacctaccaagaagaagagagtcacacgtgtgaagcagtgtcgttgcatatcc
atcgatttggattaa

KEGG   Homo sapiens (human): 64388
Entry
64388             CDS       T01001                                 
Symbol
GREM2, CKTSF1B2, DAND3, PRDC, STHAG9
Name
(RefSeq) gremlin 2, DAN family BMP antagonist
  KO
K23318  gremlin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04350  TGF-beta signaling pathway
Network
nt06507  TGFB signaling
  Element
N01428  BMP signaling pathway, BMP antagonist
Disease
H00625  Tooth agenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    64388 (GREM2)
SSDB
Motif
Pfam: DAN Cys_knot TIR_2 Arc_MA
Other DBs
NCBI-GeneID: 64388
NCBI-ProteinID: NP_071914
OMIM: 608832
HGNC: 17655
Ensembl: ENSG00000180875
UniProt: Q9H772
LinkDB
Position
1:complement(240489573..240612155)
AA seq 168 aa
MFWKLSLSLFLVAVLVKVAEARKNRPAGAIPSPYKDGSSNNSERWQHQIKEVLASSQEAL
VVTERKYLKSDWCKTQPLRQTVSEEGCRSRTILNRFCYGQCNSFYIPRHVKKEEESFQSC
AFCKPQRVTSVLVELECPGLDPPFRLKKIQKVKQCRCMSVNLSDSDKQ
NT seq 507 nt   +upstreamnt  +downstreamnt
atgttctggaagctttccctgtccttgttcctggtggcggtgctggtgaaggtggcggaa
gcccggaagaaccggccggcgggcgccatcccctcgccttacaaggacggcagcagcaac
aactcggagagatggcagcaccagatcaaggaggtgctggcctccagccaggaggccctg
gtggtcaccgagcgcaagtacctcaagagtgactggtgcaagacgcagccgctgcggcag
acggtgagcgaggagggctgccggagccgcaccatcctcaaccgcttctgctacggccag
tgcaactccttctacatcccgcggcacgtgaagaaggaggaggagtccttccagtcctgc
gccttctgcaagccccagcgcgtcacctccgtcctcgtggagctcgagtgccccggcctg
gacccacccttccgactcaagaaaatccagaaggtgaagcagtgccggtgcatgtccgtg
aacctgagcgactcggacaagcagtga

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