Homo sapiens (human): 2692
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Entry
2692 CDS
T01001
Symbol
GHRHR, GHRFR, GRFR, IGHD1B, IGHD4
Name
(RefSeq) growth hormone releasing hormone receptor
KO
K04584
growth hormone releasing hormone receptor
Organism
hsa
Homo sapiens (human)
Pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa04935
Growth hormone synthesis, secretion and action
Network
nt06324
GHRH-GH-IGF signaling
Element
N00910
GHRHR-PKA-GH signaling pathway
Disease
H00254
Growth hormone deficiency
H02035
Isolated growth hormone deficiency
Drug target
Ibutamoren mesylate:
D04491
Sermorelin (
DG00494
):
D02117
D08509
Somatorelin (
DG01168
):
D03326
D08523
Tesamorelin (
DG00495
):
D06655
D09015
<US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
2692 (GHRHR)
09150 Organismal Systems
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
2692 (GHRHR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
hsa04030
]
2692 (GHRHR)
G protein-coupled receptors [BR:
hsa04030
]
Secretin receptor family
Hypothalamic hormone
Growth hormone-releasing hormone (GHRH)
2692 (GHRHR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
7tm_2
HRM
Dicty_CAR
Motif
Other DBs
NCBI-GeneID:
2692
NCBI-ProteinID:
NP_000814
OMIM:
139191
HGNC:
4266
Ensembl:
ENSG00000106128
Pharos:
Q02643
(Tclin)
UniProt:
Q02643
A0A090N8Y6
Structure
PDB
LinkDB
All DBs
Position
7:30963953..30979528
Genome browser
AA seq
423 aa
AA seq
DB search
MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD
GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA
EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF
LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR
AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF
LNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPL
ELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLT
SMC
NT seq
1272 nt
NT seq
+upstream
nt +downstream
nt
atggaccgccggatgtggggggcccacgtcttctgcgtgttgagcccgttaccgaccgta
ttgggccacatgcacccagaatgtgacttcatcacccagctgagagaggatgagagtgcc
tgtctacaagcagcagaggagatgcccaacaccaccctgggctgccctgcgacctgggat
gggctgctgtgctggccaacggcaggctctggcgagtgggtcaccctcccctgcccggat
ttcttctctcacttcagctcagagtcaggggctgtgaaacgggattgtactatcactggc
tggtctgagccctttccaccttaccctgtggcctgccctgtgcctctggagctgctggct
gaggaggaatcttacttctccacagtgaagattatctacaccgtgggccatagcatctct
attgtagccctcttcgtggccatcaccatcctggttgctctcaggaggctccactgcccc
cggaactacgtccacacccagctgttcaccacttttatcctcaaggcgggagctgtgttc
ctgaaggatgctgcccttttccacagcgacgacactgaccactgcagcttctccactgtt
ctatgcaaggtctctgtggccgcctcccatttcgccaccatgaccaacttcagctggctg
ttggcagaagccgtctacctgaactgcctcctggcctccacctcccccagctcaaggaga
gccttctggtggctggttctcgctggctgggggctgcccgtgctcttcactggcacgtgg
gtgagctgcaaactggccttcgaggacatcgcgtgctgggacctggacgacacctccccc
tactggtggatcatcaaagggcccattgtcctctcggtcggggtgaactttgggcttttt
ctcaatattatccgcatcctggtgaggaaactggagccagctcagggcagcctccatacc
cagtctcagtattggcgtctctccaagtcgacacttttcctgatcccactctttggaatt
cactacatcatcttcaacttcctgccagacaatgctggcctgggcatccgcctccccctg
gagctgggactgggttccttccagggcttcattgttgccatcctctactgcttcctcaac
caagaggtgaggactgagatctcacggaagtggcatggccatgaccctgagcttctgcca
gcctggaggacccgtgctaagtggaccacgccttcccgctcggcggcaaaggtgctgaca
tctatgtgctag
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