KEGG   Homo sapiens (human): 27068
Entry
27068             CDS       T01001                                 
Symbol
PPA2, HSPC124, SCFAI, SCFI, SID6-306
Name
(RefSeq) inorganic pyrophosphatase 2
  KO
K01507  inorganic pyrophosphatase [EC:3.6.1.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
Disease
H01631  Acute heart failure
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    27068 (PPA2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.1  inorganic diphosphatase
     27068 (PPA2)
SSDB
Motif
Pfam: Pyrophosphatase
Other DBs
NCBI-GeneID: 27068
NCBI-ProteinID: NP_789845
OMIM: 609988
HGNC: 28883
Ensembl: ENSG00000138777
Pharos: Q9H2U2(Tbio)
UniProt: Q9H2U2
LinkDB
Position
4:complement(105369077..105474070)
AA seq 334 aa
MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY
VKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSC
GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL
YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF
RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgagcgcgctgctgcggctgctgcgcacgggtgccccagccgctgcgtgcctgcggttg
gggaccagtgcagggaccgggtcgcgccgtgctatggccctgtaccacactgaggagcgc
ggccagccctgctcgcagaattaccgcctcttctttaagaatgtaactggtcactacatt
tccccctttcatgatattcctctgaaggtgaactctaaagaggaaaatggcattcctatg
aagaaagcacgaaatgatgaatatgagaatctgtttaatatgattgtagaaatacctcgg
tggacaaatgctaaaatggagattgccaccaaggagccaatgaatcccattaaacaatat
gtaaaggatggaaagctacgctatgtggcgaatatcttcccttacaagggttatatatgg
aattatggtaccctccctcagacttgggaagatccccatgaaaaagataagagcacgaac
tgctttggagataatgatcctattgatgtttgcgaaataggctcaaagattctttcttgt
ggagaagttattcatgtgaagatccttggaattttggctcttattgatgaaggtgaaaca
gattggaaattaattgctatcaatgcgaatgatcctgaagcctcaaagtttcatgatatt
gatgatgttaagaagttcaaaccgggttacctggaagctactcttaattggtttagatta
tataaggtaccagatggaaaaccagaaaaccagtttgcttttaatggagaattcaaaaac
aaggcttttgctcttgaagttattaaatccactcatcaatgttggaaagcattgcttatg
aagaagtgtaatggaggagctataaattgcacaaacgtgcagatatctgatagccctttc
cgttgcactcaagaggaagcaagatcattagttgaatcggtatcatcttcaccaaataaa
gaaagtaatgaagaagagcaagtgtggcacttccttggcaagtga

KEGG   Homo sapiens (human): 5464
Entry
5464              CDS       T01001                                 
Symbol
PPA1, HEL-S-66p, IOPPP, PP, PP1, SID6-8061
Name
(RefSeq) inorganic pyrophosphatase 1
  KO
K01507  inorganic pyrophosphatase [EC:3.6.1.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    5464 (PPA1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.1  inorganic diphosphatase
     5464 (PPA1)
SSDB
Motif
Pfam: Pyrophosphatase
Other DBs
NCBI-GeneID: 5464
NCBI-ProteinID: NP_066952
OMIM: 179030
HGNC: 9226
Ensembl: ENSG00000180817
Pharos: Q15181(Tbio)
UniProt: Q15181 V9HWB5
Structure
LinkDB
Position
10:complement(70202835..70233429)
AA seq 289 aa
MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYADKDVFHMVVEVPRWSNAKMEI
ATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPI
DVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKP
GYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGI
SCMNTTLSESPFKCDPDAARAIVDALPPPCESACTVPTDVDKWFHHQKN
NT seq 870 nt   +upstreamnt  +downstreamnt
atgagcggcttcagcaccgaggagcgcgccgcgcccttctccctggagtaccgagtcttc
ctcaaaaatgagaaaggacaatatatatctccatttcatgatattccaatttatgcagat
aaggatgtgtttcacatggtagttgaagtaccacgctggtctaatgcaaaaatggagatt
gctacaaaggaccctttaaaccctattaaacaagatgtgaaaaaaggaaaacttcgctat
gttgcgaatttgttcccgtataaaggatatatctggaactatggtgccatccctcagact
tgggaagacccagggcacaatgataaacatactggctgttgtggtgacaatgacccaatt
gatgtgtgtgaaattggaagcaaggtatgtgcaagaggtgaaataattggcgtgaaagtt
ctaggcatattggctatgattgacgaaggggaaaccgactggaaagtcattgccattaat
gtggatgatcctgatgcagccaattataatgatatcaatgatgtcaaacggctgaaacct
ggctacttagaagctactgtggactggtttagaaggtataaggttcctgatggaaaacca
gaaaatgagtttgcgtttaatgcagaatttaaagataaggactttgccattgatattatt
aaaagcactcatgaccattggaaagcattagtgactaagaaaacgaatggaaaaggaatc
agttgcatgaatacaactttgtctgagagccccttcaagtgtgatcctgatgctgccaga
gccattgtggatgctttaccaccaccctgtgaatctgcctgcacagtaccaacagacgtg
gataagtggttccatcaccagaaaaactaa

KEGG   Homo sapiens (human): 64077
Entry
64077             CDS       T01001                                 
Symbol
LHPP, HDHD2B
Name
(RefSeq) phospholysine phosphohistidine inorganic pyrophosphate phosphatase
  KO
K11725  phospholysine phosphohistidine inorganic pyrophosphate phosphatase [EC:3.6.1.1 3.1.3.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    64077 (LHPP)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    64077 (LHPP)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.1  inorganic diphosphatase
     64077 (LHPP)
Protein phosphatases and associated proteins [BR:hsa01009]
 HAD phosphatases
  Other HAD phosphatases
   64077 (LHPP)
SSDB
Motif
Pfam: Hydrolase_like Hydrolase_6 Hydrolase HAD_2
Other DBs
NCBI-GeneID: 64077
NCBI-ProteinID: NP_071409
OMIM: 617231
HGNC: 30042
Ensembl: ENSG00000107902
Pharos: Q9H008(Tbio)
UniProt: Q9H008
Structure
LinkDB
Position
10:124461823..124614141
AA seq 270 aa
MAPWGKRLAGVRGVLLDISGVLYDSGAGGGTAIAGSVEAVARLKRSRLKVRFCTNESQKS
RAELVGQLQRLGFDISEQEVTAPAPAACQILKEQGLRPYLLIHDGVRSEFDQIDTSNPNC
VVIADAGESFSYQNMNNAFQVLMELEKPVLISLGKGRYYKETSGLMLDVGPYMKALEYAC
GIKAEVVGKPSPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRALQVRTGKFRP
SDEHHPEVKADGYVDNLAEAVDLLLQHADK
NT seq 813 nt   +upstreamnt  +downstreamnt
atggcaccgtggggcaagcggctggctggcgtgcgcggggtgctgcttgacatctcgggc
gtgctgtacgacagcggcgcgggcggcggcacggccatcgccggctcggtggaggcggtg
gccagactgaagcgttcccggctgaaggtgaggttctgcaccaacgagtcgcagaagtcc
cgggcagagctggtggggcagcttcagaggctgggatttgacatctctgagcaggaggtg
accgccccggcaccagctgcctgccagatcctgaaggagcaaggcctgcgaccatacctg
ctcatccatgacggagtccgctcagaatttgatcagatcgacacatccaacccaaactgt
gtggtaattgcagacgcaggagaaagcttttcttatcaaaacatgaataacgccttccag
gtgctcatggagctggaaaaacctgtgctcatatcactgggaaaagggcgttactacaag
gagacctctggcctgatgctggacgttggtccctacatgaaggcgcttgagtatgcctgt
ggcatcaaagccgaggtggtggggaagccttctcctgagtttttcaagtctgccctgcaa
gcgataggagtggaagcccaccaggccgtcatgattggggacgatatcgtgggcgacgtc
ggcggtgcccagcggtgtggaatgagagcgctgcaggtgcgcaccgggaagttcaggccc
agtgacgagcaccatccggaagtgaaggctgatgggtacgtggacaacctcgcagaggca
gtggacctgctgctgcagcacgccgacaagtga

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