Homo sapiens (human): 273
Help
Entry
273 CDS
T01001
Symbol
AMPH, AMPH1
Name
(RefSeq) amphiphysin
KO
K12562
amphiphysin
Organism
hsa
Homo sapiens (human)
Pathway
hsa04144
Endocytosis
hsa04666
Fc gamma R-mediated phagocytosis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
273 (AMPH)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
273 (AMPH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
273 (AMPH)
Membrane trafficking [BR:
hsa04131
]
Endocytosis
Clathrin-mediated endocytosis
Other core components
273 (AMPH)
Bin/Amphiphysin/Rvs (BAR) family proteins
N-BAR proteins
273 (AMPH)
Others
Actin-binding proteins
Nucleation-promoting factors (NPFs)
273 (AMPH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BAR
SH3_9
SH3_1
SH3_2
HD_3
THP2
Motif
Other DBs
NCBI-GeneID:
273
NCBI-ProteinID:
NP_001626
OMIM:
600418
HGNC:
471
Ensembl:
ENSG00000078053
UniProt:
P49418
Structure
PDB
LinkDB
All DBs
Position
7:complement(38383704..38631373)
Genome browser
AA seq
695 aa
AA seq
DB search
MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQREL
RGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLT
LDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVF
EEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHAD
KAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKG
PPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFK
PEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSM
ICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTL
VSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVI
PSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSA
PAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQ
DAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
NT seq
2088 nt
NT seq
+upstream
nt +downstream
nt
atggccgacatcaagacgggcatcttcgccaagaacgtccagaagcgactcaaccgcgcg
caggaaaaggtcctccaaaagctggggaaagctgatgagacaaaagacgaacagttcgaa
gaatatgtccagaacttcaaacggcaagaagcagagggtaccagacttcagcgagaactc
cgaggatatttagcagcaatcaaaggcatgcaggaggcctccatgaagctcacagagtcg
ctgcatgaagtctatgagcctgactggtatgggcgggaagatgtgaaaatggttggtgag
aaatgtgatgtgctgtgggaagacttccatcaaaaactcgtggatgggtccttgctaaca
ctggatacctacctggggcaatttcctgacataaagaatcgcatcgccaagcgcagcagg
aagctagtggactatgacagtgcccgccaccatctggaagctctgcagagctccaagagg
aaggatgagagtcgaatctctaaggcagaagaagaatttcagaaagcacagaaagtgttt
gaagagtttaacgttgacttacaagaagagttaccatcattatggtcaagacgagttgga
ttttatgttaatactttcaaaaacgtctccagccttgaagccaagtttcataaggaaatt
gcggtgctttgccacaaactgtatgaagtgatgacaaaactgggtgaccagcacgccgac
aaggccttcaccatccaaggagcgcccagtgattcgggtcctctccgcattgcaaagaca
ccatcaccgcctgaggagccttcacccctcccgagcccgacagcaagtccaaatcataca
ttagcacctgcgtctcccgcaccagcacggcctcggtcaccttcacagacaaggaaaggg
cctcctgtcccacctctacctaaagtcaccccgacaaaggaactgcagcaggagaacatc
atcagtttctttgaggacaactttgttccagaaatcagtgtgacaacaccttcccagaat
gaagtccctgaggtgaagaaagaggagactttgctggatctggactttgatcctttcaag
cccgaggtgacacctgcaggttctgctggagtgacccactcacccatgtctcagacattg
ccctgggacctatggacgacaagcactgatttggtacagccggcttctggtggttcattt
aatggattcacacagccccaggatacttcattattcacaatgcagacagaccagagtatg
atctgcaacttggctgaatctgaacaggctccacccacagagccaaaagcagaggagcct
ctggctgctgtcacacctgccgttggtctggaccttggaatggacactcgggctgaggag
ccagtggaggaggcagtgatcatacctggagctgatgctgatgcagctgttggaaccttg
gtgtcagcagctgagggggccccaggagaggaagcagaggcggagaaggccactgtccct
gccggggaaggagtaagtttagaggaggccaaaattggaactgaaaccactgagggtgca
gagagtgcccaacctgaagcagaggagctcgaagcaacagtgcctcaggagaaggtcatt
ccttcggtggtcatagagcctgcctccaaccatgaagaggaaggagaaaacgaaataact
ataggtgcagagcccaaggagaccaccgaggacgcggctcctccgggccccaccagcgag
acaccggagctggctacggagcagaagcctatccaggaccctcagcccacgccttctgca
ccagccatgggggctgctgaccagctagcatctgcaagggaggcctctcaggaattgcct
cctggctttctctacaaggtggaaacactgcatgattttgaggcagcaaattctgatgaa
cttaccttacaaaggggtgatgtggtgctggtggtcccctcagattcagaagctgatcag
gatgcaggctggctggtgggagtgaaggaatcagactggcttcagtacagagaccttgcc
acctacaaaggcctctttccagagaacttcacccgacgcttagattag
Homo sapiens (human): 274
Help
Entry
274 CDS
T01001
Symbol
BIN1, AMPH2, AMPHL, CNM2, SH3P9
Name
(RefSeq) bridging integrator 1
KO
K12562
amphiphysin
Organism
hsa
Homo sapiens (human)
Pathway
hsa04144
Endocytosis
hsa04666
Fc gamma R-mediated phagocytosis
Disease
H00700
Centronuclear myopathy
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
274 (BIN1)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
274 (BIN1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
274 (BIN1)
Membrane trafficking [BR:
hsa04131
]
Endocytosis
Clathrin-mediated endocytosis
Other core components
274 (BIN1)
Bin/Amphiphysin/Rvs (BAR) family proteins
N-BAR proteins
274 (BIN1)
Others
Actin-binding proteins
Nucleation-promoting factors (NPFs)
274 (BIN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BAR
SH3_9
SH3_2
SH3_1
Exo70_N
THP2
Motif
Other DBs
NCBI-GeneID:
274
NCBI-ProteinID:
NP_647593
OMIM:
601248
HGNC:
1052
Ensembl:
ENSG00000136717
UniProt:
O00499
A0A024RAF1
Structure
PDB
LinkDB
All DBs
Position
2:complement(127048023..127107154)
Genome browser
AA seq
593 aa
AA seq
DB search
MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTR
LQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVD
QALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEK
AAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVN
TFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPP
DGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILS
LFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLW
EPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGET
AASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQ
LKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atggcagagatgggcagtaaaggggtgacggcgggaaagatcgccagcaacgtgcagaag
aagctcacccgcgcgcaggagaaggttctccagaagctggggaaggcagatgagaccaag
gatgagcagtttgagcagtgcgtccagaatttcaacaagcagctgacggagggcacccgg
ctgcagaaggatctccggacctacctggcctccgtcaaagccatgcacgaggcttccaag
aagctgaatgagtgtctgcaggaggtgtatgagcccgattggcccggcagggatgaggca
aacaagatcgcagagaacaacgacctgctgtggatggattaccaccagaagctggtggac
caggcgctgctgaccatggacacgtacctgggccagttccccgacatcaagtcacgcatt
gccaagcgggggcgcaagctggtggactacgacagtgcccggcaccactacgagtccctt
caaactgccaaaaagaaggatgaagccaaaattgccaagcctgtctcgctgcttgagaaa
gccgccccccagtggtgccaaggcaaactgcaggctcatctcgtagctcaaactaacctg
ctccgaaatcaggccgaggaggagctcatcaaagcccagaaggtgtttgaggagatgaat
gtggatctgcaggaggagctgccgtccctgtggaacagccgcgtaggtttctacgtcaac
acgttccagagcatcgcgggcctggaggaaaacttccacaaggagatgagcaagctcaac
cagaacctcaatgatgtgctggtcggcctggagaagcaacacgggagcaacaccttcacg
gtcaaggcccagcccagtgacaacgcgcctgcaaaagggaacaagagcccttcgcctcca
gatggctcccctgccgccacccccgagatcagagtcaaccacgagccagagccggccggc
ggggccacgcccggggccaccctccccaagtccccatctcagctccggaaaggcccacca
gtccctccgcctcccaaacacaccccgtccaaggaagtcaagcaggagcagatcctcagc
ctgtttgaggacacgtttgtccctgagatcagcgtgaccaccccctcccagtttgaggcc
ccggggcctttctcggagcaggccagtctgctggacctggactttgaccccctcccgccc
gtgacgagccctgtgaaggcacccacgccctctggtcagtcaattccatgggacctctgg
gagcccacagagagtccagccggcagcctgccttccggggagcccagcgctgccgagggc
acctttgctgtgtcctggcccagccagacggccgagccggggcctgcccaaccagcagag
gcctcggaggtggcgggtgggacccaacctgcggctggagcccaggagccaggggagacg
gcggcaagtgaagcagcctccagctctcttcctgctgtcgtggtggagaccttcccagca
actgtgaatggcaccgtggagggcggcagtggggccgggcgcttggacctgcccccaggt
ttcatgttcaaggtacaggcccagcacgactacacggccactgacacagacgagctgcag
ctcaaggctggtgatgtggtgctggtgatccccttccagaaccctgaagagcaggatgaa
ggctggctcatgggcgtgaaggagagcgactggaaccagcacaaggagctggagaagtgc
cgtggcgtcttccccgagaacttcactgagagggtcccatga
DBGET
integrated database retrieval system
