KEGG   Homo sapiens (human): 27329
Entry
27329             CDS       T01001                                 
Symbol
ANGPTL3, ANG-5, ANGPT5, ANL3, FHBL2
Name
(RefSeq) angiopoietin like 3
  KO
K22288  angiopoietin-like 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04979  Cholesterol metabolism
Disease
H01270  Familial hypobetalipoproteinemia
Drug target
Evinacumab: D11753<JP/US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    27329 (ANGPTL3)
SSDB
Motif
Pfam: Fibrinogen_C FAM186A-B_C Crescentin DUF4201 DUF3209 ISG65-75 DUF1664
Other DBs
NCBI-GeneID: 27329
NCBI-ProteinID: NP_055310
OMIM: 604774
HGNC: 491
Ensembl: ENSG00000132855
UniProt: Q9Y5C1
Structure
LinkDB
Position
1:62597520..62606313
AA seq 460 aa
MFTIKLLLFIVPLVISSRIDQDNSSFDSLSPEPKSRFAMLDDVKILANGLLQLGHGLKDF
VHKTKGQINDIFQKLNIFDQSFYDLSLQTSEIKEEEKELRRTTYKLQVKNEEVKNMSLEL
NSKLESLLEEKILLQQKVKYLEEQLTNLIQNQPETPEHPEVTSLKTFVEKQDNSIKDLLQ
TVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEISLSSKPRAPRTTPFLQLNEIRNVKHD
GIPAECTTIYNRGEHTSGMYAIRPSNSQVFHVYCDVISGSPWTLIQHRIDGSQNFNETWE
NYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEYSFYLGNHETNYTL
HLVAITGNVPNAIPENKDLVFSTWDHKAKGHFNCPEGYSGGWWWHDECGENNLNGKYNKP
RAKSKPERRRGLSWKSQNGRLYSIKSTKMLIHPTDSESFE
NT seq 1383 nt   +upstreamnt  +downstreamnt
atgttcacaattaagctccttctttttattgttcctctagttatttcctccagaattgat
caagacaattcatcatttgattctctatctccagagccaaaatcaagatttgctatgtta
gacgatgtaaaaattttagccaatggcctccttcagttgggacatggtcttaaagacttt
gtccataagacgaagggccaaattaatgacatatttcaaaaactcaacatatttgatcag
tctttttatgatctatcgctgcaaaccagtgaaatcaaagaagaagaaaaggaactgaga
agaactacatataaactacaagtcaaaaatgaagaggtaaagaatatgtcacttgaactc
aactcaaaacttgaaagcctcctagaagaaaaaattctacttcaacaaaaagtgaaatat
ttagaagagcaactaactaacttaattcaaaatcaacctgaaactccagaacacccagaa
gtaacttcacttaaaacttttgtagaaaaacaagataatagcatcaaagaccttctccag
accgtggaagaccaatataaacaattaaaccaacagcatagtcaaataaaagaaatagaa
aatcagctcagaaggactagtattcaagaacccacagaaatttctctatcttccaagcca
agagcaccaagaactactccctttcttcagttgaatgaaataagaaatgtaaaacatgat
ggcattcctgctgaatgtaccaccatttataacagaggtgaacatacaagtggcatgtat
gccatcagacccagcaactctcaagtttttcatgtctactgtgatgttatatcaggtagt
ccatggacattaattcaacatcgaatagatggatcacaaaacttcaatgaaacgtgggag
aactacaaatatggttttgggaggcttgatggagaattttggttgggcctagagaagata
tactccatagtgaagcaatctaattatgttttacgaattgagttggaagactggaaagac
aacaaacattatattgaatattctttttacttgggaaatcacgaaaccaactatacgcta
catctagttgcgattactggcaatgtccccaatgcaatcccggaaaacaaagatttggtg
ttttctacttgggatcacaaagcaaaaggacacttcaactgtccagagggttattcagga
ggctggtggtggcatgatgagtgtggagaaaacaacctaaatggtaaatataacaaacca
agagcaaaatctaagccagagaggagaagaggattatcttggaagtctcaaaatggaagg
ttatactctataaaatcaaccaaaatgttgatccatccaacagattcagaaagctttgaa
tga

KEGG   Homo sapiens (human): 51129
Entry
51129             CDS       T01001                                 
Symbol
ANGPTL4, ARP4, FIAF, HARP, HFARP, NL2, PGAR, TGQTL, UNQ171, pp1158
Name
(RefSeq) angiopoietin like 4
  KO
K08767  angiopoietin-like 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa03320  PPAR signaling pathway
hsa04979  Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    51129 (ANGPTL4)
  09154 Digestive system
   04979 Cholesterol metabolism
    51129 (ANGPTL4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    51129 (ANGPTL4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   51129 (ANGPTL4)
SSDB
Motif
Pfam: Fibrinogen_C ATG14 SlyX DivIC MerC Helo_like_N
Other DBs
NCBI-GeneID: 51129
NCBI-ProteinID: NP_647475
OMIM: 605910
HGNC: 16039
Ensembl: ENSG00000167772
UniProt: Q9BY76
Structure
LinkDB
Position
19:8364155..8374370
AA seq 406 aa
MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAE
RTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLF
HKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSR
LHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRP
WEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAY
SLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLN
GQYFRSIPQQRQKLKKGIFWKTWRGRYYPLQATTMLIQPMAAEAAS
NT seq 1221 nt   +upstreamnt  +downstreamnt
atgagcggtgctccgacggccggggcagccctgatgctctgcgccgccaccgccgtgcta
ctgagcgctcagggcggacccgtgcagtccaagtcgccgcgctttgcgtcctgggacgag
atgaatgtcctggcgcacggactcctgcagctcggccaggggctgcgcgaacacgcggag
cgcacccgcagtcagctgagcgcgctggagcggcgcctgagcgcgtgcgggtccgcctgt
cagggaaccgaggggtccaccgacctcccgttagcccctgagagccgggtggaccctgag
gtccttcacagcctgcagacacaactcaaggctcagaacagcaggatccagcaactcttc
cacaaggtggcccagcagcagcggcacctggagaagcagcacctgcgaattcagcatctg
caaagccagtttggcctcctggaccacaagcacctagaccatgaggtggccaagcctgcc
cgaagaaagaggctgcccgagatggcccagccagttgacccggctcacaatgtcagccgc
ctgcaccggctgcccagggattgccaggagctgttccaggttggggagaggcagagtgga
ctatttgaaatccagcctcaggggtctccgccatttttggtgaactgcaagatgacctca
gatggaggctggacagtaattcagaggcgccacgatggctcagtggacttcaaccggccc
tgggaagcctacaaggcggggtttggggatccccacggcgagttctggctgggtctggag
aaggtgcatagcatcacgggggaccgcaacagccgcctggccgtgcagctgcgggactgg
gatggcaacgccgagttgctgcagttctccgtgcacctgggtggcgaggacacggcctat
agcctgcagctcactgcacccgtggccggccagctgggcgccaccaccgtcccacccagc
ggcctctccgtacccttctccacttgggaccaggatcacgacctccgcagggacaagaac
tgcgccaagagcctctctggaggctggtggtttggcacctgcagccattccaacctcaac
ggccagtacttccgctccatcccacagcagcggcagaagcttaagaagggaatcttctgg
aagacctggcggggccgctactacccgctgcaggccaccaccatgttgatccagcccatg
gcagcagaggcagcctcctag

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