Homo sapiens (human): 27349
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Entry
27349 CDS
T01001
Symbol
MCAT, FASN2C, MCT, MCT1, MT, NET62, OPA15, fabD
Name
(RefSeq) malonyl-CoA-acyl carrier protein transacylase
KO
K00645
[acyl-carrier-protein] S-malonyltransferase [EC:
2.3.1.39
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00061
Fatty acid biosynthesis
hsa01100
Metabolic pathways
hsa01212
Fatty acid metabolism
Module
hsa_M00082
Fatty acid biosynthesis, initiation
hsa_M00873
Fatty acid biosynthesis in mitochondria, animals
Disease
H01020
Optic atrophy
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
27349 (MCAT)
09110 Biosynthesis of other secondary metabolites
00333 Prodigiosin biosynthesis
27349 (MCAT)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
hsa01004
]
27349 (MCAT)
Enzymes [BR:
hsa01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.39 [acyl-carrier-protein] S-malonyltransferase
27349 (MCAT)
Lipid biosynthesis proteins [BR:
hsa01004
]
Fatty acid synthase
Component type
27349 (MCAT)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Acyl_transf_1
Motif
Other DBs
NCBI-GeneID:
27349
NCBI-ProteinID:
NP_775738
OMIM:
614479
HGNC:
29622
Ensembl:
ENSG00000100294
Pharos:
Q8IVS2
(Tbio)
UniProt:
Q8IVS2
Structure
PDB
PDBj
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All DBs
Position
22:complement(43132206..43143398)
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AA seq
390 aa
AA seq
DB search
MSVRVARVAWVRGLGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPG
QCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHC
QPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFAEGLYAVKIRAE
AMQEASEAVPSGMLSVLGQPQSKFNFACLEAREHCKSLGIENPVCEVSNYLFPDCRVISG
HQEALRFLQKNSSKFHFRRTRMLPVSGAFHTRLMEPAVEPLTQALKAVDIKKPLVSVYSN
VHAHRYRHPGHIHKLLAQQLVSPVKWEQTMHAIYERKKGRGFPQTFEVGPGRQLGAILKS
CNMQAWKSYSAVDVLQTLEHVDLDPQEPPR
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgagcgtccgggtcgcacgggtagcgtgggtcaggggcttgggcgccagctaccgccgc
ggcgcctcgagcttcccggtgcctccgccgggcgcccagggtgtagcggagctgctgcga
gatgcgaccggggcggaggaggaggcgccctgggcggcgacggagcggcgaatgccgggc
cagtgctccgtgctgctcttcccgggccagggcagccaggtggtgggcatgggccgcggt
ctgctcaactacccgcgcgtccgcgaactctacgccgccgcccgccgcgtgctgggctac
gacctgctggaactgagcctgcacgggccgcaggagaccctggaccgcaccgtgcactgt
cagcccgcgatcttcgtggcatcgctggccgctgtcgagaaactacatcacctgcagccc
tcggtgattgagaactgtgttgctgctgctggattcagtgtgggagagtttgcagcccta
gtgtttgccggagccatggaatttgctgaaggtttgtatgcagtgaaaatccgagctgag
gccatgcaggaagcttcagaagctgtccccagtgggatgctgtctgtcctcggccagcct
cagtccaagttcaacttcgcctgtttggaagcccgggaacactgcaagtctttaggcata
gagaaccccgtatgtgaagtgtccaactacctctttccagattgcagggtgatttcagga
caccaagaggctctacggtttctccagaagaattcctctaagtttcatttcagacgcacc
aggatgttgccggttagtggcgcattccacacccgcctcatggagccagccgtggagccc
ctgacgcaagctttaaaggcagtcgacattaagaagcctctggtttctgtctactccaac
gtccacgcgcatagatacaggcatcccgggcacatccacaagctgctggcccagcagctg
gtctccccagtgaagtgggagcagacgatgcatgccatatacgaaaggaaaaagggcagg
gggttcccccaaactttcgaagtaggccctggcaggcagctgggagccatcctgaagagc
tgtaacatgcaggcctggaagtcctacagcgccgtggatgtgctgcagaccctcgaacat
gtggacctggaccctcaggagcccccgagatga
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