Homo sapiens (human): 2876 Help Entry 2876              CDS       T01001                                  Symbol GPX1, GPXD, GSHPX1 Name (RefSeq) glutathione peroxidase 1   KO K00432   glutathione peroxidase [EC:1.11.1.9] Organism hsa  Homo sapiens (human) Pathway hsa00480   Glutathione metabolism hsa01100   Metabolic pathways hsa04918   Thyroid hormone synthesis hsa05014   Amyotrophic lateral sclerosis hsa05016   Huntington disease hsa05022   Pathways of neurodegeneration - multiple diseases Network nt06026  Glutathione biosynthesis nt06525  Ferroptosis   Element N01589   Glutathione biosynthesis Disease H00668   Anemia due to disorders of glutathione metabolism Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09106 Metabolism of other amino acids    00480 Glutathione metabolism     2876 (GPX1)  09150 Organismal Systems   09152 Endocrine system    04918 Thyroid hormone synthesis     2876 (GPX1)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     2876 (GPX1)    05016 Huntington disease     2876 (GPX1)    05022 Pathways of neurodegeneration - multiple diseases     2876 (GPX1) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.11  Acting on a peroxide as acceptor    1.11.1  Peroxidases     1.11.1.9  glutathione peroxidase      2876 (GPX1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  GSHPx Redoxin AhpC-TSA Motif Other DBs NCBI-GeneID:  2876 NCBI-ProteinID:  NP_000572 OMIM:  138320 HGNC:  4553 Ensembl:  ENSG00000233276 UniProt:  P07203 Q7L4Q3 Structure PDB LinkDB All DBs Position 3:complement(49357176..49358353) Genome browser AA seq 203 aa AA seqDB search MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMN ELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGA GAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYS RRFQTIDIEPDIEALLSQGPSCA NT seq 612 nt NT seq  +upstreamnt  +downstreamnt atgtgtgctgctcggctagcggcggcggcggcggcggcccagtcggtgtatgccttctcg gcgcgcccgctggccggcggggagcctgtgagcctgggctccctgcggggcaaggtacta cttatcgagaatgtggcgtccctctgaggcaccacggtccgggactacacccagatgaac gagctgcagcggcgcctcggaccccggggcctggtggtgctcggcttcccgtgcaaccag tttgggcatcaggagaacgccaagaacgaagagattctgaattccctcaagtacgtccgg cctggtggtgggttcgagcccaacttcatgctcttcgagaagtgcgaggtgaacggtgcg ggggcgcaccctctcttcgccttcctgcgggaggccctgccagctcccagcgacgacgcc accgcgcttatgaccgaccccaagctcatcacctggtctccggtgtgtcgcaacgatgtt gcctggaactttgagaagttcctggtgggccctgacggtgtgcccctacgcaggtacagc cgccgcttccagaccattgacatcgagcctgacatcgaagccctgctgtctcaagggccc agctgtgcctag

Homo sapiens (human): 2877 Help Entry 2877              CDS       T01001                                  Symbol GPX2, GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2 Name (RefSeq) glutathione peroxidase 2   KO K00432   glutathione peroxidase [EC:1.11.1.9] Organism hsa  Homo sapiens (human) Pathway hsa00480   Glutathione metabolism hsa01100   Metabolic pathways hsa04918   Thyroid hormone synthesis hsa05014   Amyotrophic lateral sclerosis hsa05016   Huntington disease hsa05022   Pathways of neurodegeneration - multiple diseases Network nt06026  Glutathione biosynthesis nt06525  Ferroptosis   Element N01589   Glutathione biosynthesis Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09106 Metabolism of other amino acids    00480 Glutathione metabolism     2877 (GPX2)  09150 Organismal Systems   09152 Endocrine system    04918 Thyroid hormone synthesis     2877 (GPX2)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     2877 (GPX2)    05016 Huntington disease     2877 (GPX2)    05022 Pathways of neurodegeneration - multiple diseases     2877 (GPX2) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.11  Acting on a peroxide as acceptor    1.11.1  Peroxidases     1.11.1.9  glutathione peroxidase      2877 (GPX2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  GSHPx Redoxin Motif Other DBs NCBI-GeneID:  2877 NCBI-ProteinID:  NP_002074 OMIM:  138319 HGNC:  4554 Ensembl:  ENSG00000176153 UniProt:  P18283 Structure PDB LinkDB All DBs Position 14:complement(64939158..64942745) Genome browser AA seq 190 aa AA seqDB search MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRR LVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLK DKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEP DIKRLLKVAI NT seq 573 nt NT seq  +upstreamnt  +downstreamnt atggctttcattgccaagtccttctatgacctcagtgccatcagcctggatggggagaag gtagatttcaatacgttccggggcagggccgtgctgattgagaatgtggcttcgctctga ggcacaaccacccgggacttcacccagctcaacgagctgcaatgccgctttcccaggcgc ctggtggtccttggcttcccttgcaaccaatttggacatcaggagaactgtcagaatgag gagatcctgaacagtctcaagtatgtccgtcctgggggtggataccagcccaccttcacc cttgtccaaaaatgtgaggtgaatgggcagaacgagcatcctgtcttcgcctacctgaag gacaagctcccctacccttatgatgacccattttccctcatgaccgatcccaagctcatc atttggagccctgtgcgccgctcagatgtggcctggaactttgagaagttcctcataggg ccggagggagagcccttccgacgctacagccgcaccttcccaaccatcaacattgagcct gacatcaagcgcctccttaaagttgccatatag

Homo sapiens (human): 2878 Help Entry 2878              CDS       T01001                                  Symbol GPX3, GPx-P, GSHPx-3, GSHPx-P Name (RefSeq) glutathione peroxidase 3   KO K00432   glutathione peroxidase [EC:1.11.1.9] Organism hsa  Homo sapiens (human) Pathway hsa00480   Glutathione metabolism hsa01100   Metabolic pathways hsa04918   Thyroid hormone synthesis hsa05014   Amyotrophic lateral sclerosis hsa05016   Huntington disease hsa05022   Pathways of neurodegeneration - multiple diseases Network nt06026  Glutathione biosynthesis nt06525  Ferroptosis   Element N01589   Glutathione biosynthesis Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09106 Metabolism of other amino acids    00480 Glutathione metabolism     2878 (GPX3)  09150 Organismal Systems   09152 Endocrine system    04918 Thyroid hormone synthesis     2878 (GPX3)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     2878 (GPX3)    05016 Huntington disease     2878 (GPX3)    05022 Pathways of neurodegeneration - multiple diseases     2878 (GPX3) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.11  Acting on a peroxide as acceptor    1.11.1  Peroxidases     1.11.1.9  glutathione peroxidase      2878 (GPX3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  GSHPx Motif Other DBs NCBI-GeneID:  2878 NCBI-ProteinID:  NP_002075 OMIM:  138321 HGNC:  4555 Ensembl:  ENSG00000211445 UniProt:  P22352 Structure PDB LinkDB All DBs Position 5:151020591..151028988 Genome browser AA seq 226 aa AA seqDB search MARLLQASCLLSLLLAGFVSQSRGQEKSKMDCHGGISGTIYEYGALTIDGEEYIPFKQYA GKYVLFVNVASYUGLTGQYIELNALQEELAPFGLVILGFPCNQFGKQEPGENSEILPTLK YVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTSELLGTSDRLFWEPMKVHDIR WNFEKFLVGPDGIPIMRWHHRTTVSNVKMDILSYMRRQAALGVKRK NT seq 681 nt NT seq  +upstreamnt  +downstreamnt atggcccggctgctgcaggcgtcctgcctgctttccctgctcctggccggcttcgtctcg cagagccggggacaagagaagtcgaagatggactgccatggtggcataagtggcaccatt tacgagtacggagccctcaccattgatggggaggagtacatccccttcaagcagtatgct ggcaaatacgtcctctttgtcaacgtggccagctactgaggcctgacgggccagtacatt gaactgaatgcactacaggaagagcttgcaccattcggtctggtcattctgggctttccc tgcaaccaatttggaaaacaggaaccaggagagaactcagagatccttcctaccctcaag tatgtccgaccaggtggaggctttgtccctaatttccagctctttgagaaaggggatgtc aatggagagaaagagcagaaattctacactttcctaaagaactcctgtcctcccacctcg gagctcctgggtacatctgaccgcctcttctgggaacccatgaaggttcacgacatccgc tggaactttgagaagttcctggtggggccagatggtatacccatcatgcgctggcaccac cggaccacggtcagcaacgtcaagatggacatcctgtcctacatgaggcggcaggcagcc ctgggggtcaagaggaagtaa

Homo sapiens (human): 2879 Help Entry 2879              CDS       T01001                                  Symbol GPX4, GPx-4, GSHPx-4, MCSP, PHGPx, SMDS, snGPx, snPHGPx Name (RefSeq) glutathione peroxidase 4   KO K05361   phospholipid-hydroperoxide glutathione peroxidase [EC:1.11.1.12] Organism hsa  Homo sapiens (human) Pathway hsa00480   Glutathione metabolism hsa00590   Arachidonic acid metabolism hsa01100   Metabolic pathways hsa04216   Ferroptosis Network nt06026  Glutathione biosynthesis nt06525  Ferroptosis   Element N01589   Glutathione biosynthesis Disease H01825   Spondylometaphyseal dysplasia, Sedaghatian type Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00590 Arachidonic acid metabolism     2879 (GPX4)   09106 Metabolism of other amino acids    00480 Glutathione metabolism     2879 (GPX4)  09140 Cellular Processes   09143 Cell growth and death    04216 Ferroptosis     2879 (GPX4) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.11  Acting on a peroxide as acceptor    1.11.1  Peroxidases     1.11.1.12  phospholipid-hydroperoxide glutathione peroxidase      2879 (GPX4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  GSHPx AhpC-TSA Motif Other DBs NCBI-GeneID:  2879 NCBI-ProteinID:  NP_002076 OMIM:  138322 HGNC:  4556 Ensembl:  ENSG00000167468 UniProt:  P36969 Structure PDB LinkDB All DBs Position 19:1103994..1106779 Genome browser AA seq 197 aa AA seqDB search MSLGRLCRLLKPALLCGALAAPGLAGTMCASRDDWRCARSMHEFSAKDIDGHMVNLDKYR GFVCIVTNVASQUGKTEVNYTQLVDLHARYAECGLRILAFPCNQFGKQEPGSNEEIKEFA AGYNVKFDMFSKICVNGDDAHPLWKWMKIQPKGKGILGNAIKWNFTKFLIDKNGCVVKRY GPMEEPLVIEKDLPHYF NT seq 594 nt NT seq  +upstreamnt  +downstreamnt atgagcctcggccgcctttgccgcctactgaagccggcgctgctctgtggggctctggcc gcgcctggcctggccgggaccatgtgcgcgtcccgggacgactggcgctgtgcgcgctcc atgcacgagttttccgccaaggacatcgacgggcacatggttaacctggacaagtaccgg ggcttcgtgtgcatcgtcaccaacgtggcctcccagtgaggcaagaccgaagtaaactac actcagctcgtcgacctgcacgcccgatacgctgagtgtggtttgcggatcctggccttc ccgtgtaaccagttcgggaagcaggagccagggagtaacgaagagatcaaagagttcgcc gcgggctacaacgtcaaattcgatatgttcagcaagatctgcgtgaacggggacgacgcc cacccgctgtggaagtggatgaagatccaacccaagggcaagggcatcctgggaaatgcc atcaagtggaacttcaccaagttcctcatcgacaagaacggctgcgtggtgaagcgctac ggacccatggaggagcccctggtgatagagaaggacctgccccactatttctag

Homo sapiens (human): 2880 Help Entry 2880              CDS       T01001                                  Symbol GPX5, EGLP, GPx-5, GSHPx-5, HEL-S-75p Name (RefSeq) glutathione peroxidase 5   KO K00432   glutathione peroxidase [EC:1.11.1.9] Organism hsa  Homo sapiens (human) Pathway hsa00480   Glutathione metabolism hsa01100   Metabolic pathways hsa04918   Thyroid hormone synthesis hsa05014   Amyotrophic lateral sclerosis hsa05016   Huntington disease hsa05022   Pathways of neurodegeneration - multiple diseases Network nt06026  Glutathione biosynthesis nt06525  Ferroptosis   Element N01589   Glutathione biosynthesis Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09106 Metabolism of other amino acids    00480 Glutathione metabolism     2880 (GPX5)  09150 Organismal Systems   09152 Endocrine system    04918 Thyroid hormone synthesis     2880 (GPX5)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     2880 (GPX5)    05016 Huntington disease     2880 (GPX5)    05022 Pathways of neurodegeneration - multiple diseases     2880 (GPX5) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.11  Acting on a peroxide as acceptor    1.11.1  Peroxidases     1.11.1.9  glutathione peroxidase      2880 (GPX5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  GSHPx Motif Other DBs NCBI-GeneID:  2880 NCBI-ProteinID:  NP_001500 OMIM:  603435 HGNC:  4557 Ensembl:  ENSG00000224586 UniProt:  O75715 V9HWN8 Structure PDB LinkDB All DBs Position 6:28525881..28534955 Genome browser AA seq 221 aa AA seqDB search MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK NT seq 666 nt NT seq  +upstreamnt  +downstreamnt atgactacacagttaagggtcgtccatctgcttccccttctcctagcctgctttgtgcaa acaagtcccaagcaggagaagatgaagatggattgccacaaagacgagaaaggcaccatc tatgactatgaggccatcgcacttaataagaatgaatatgtttccttcaagcagtatgtg ggcaagcacatcctcttcgtcaacgtggccacctactgtggtctgacagcgcaatatcct gaactaaatgcactccaggaggagctgaagccctatggtctagttgtgttgggctttccc tgcaaccaatttggaaagcaagaaccaggagataacaaagagattcttcctgggctcaag tatgtccgtccagggggaggatttgtacctagtttccagctttttgagaaaggggatgtg aatggtgaaaaagaacagaaagtcttcagtttcttgaagcactcctgtcctcatccctct gagattttgggcacattcaaatctatatcctgggaccctgtaaaggtccatgacatccgt tggaactttgaaaagttcctggtggggcctgatggaatccctgtcatgcgctggtcccac cgggctacggtcagctcagtcaagacagacatcctggcgtacttgaagcaattcaaaacc aaatag

Homo sapiens (human): 257202 Help Entry 257202            CDS       T01001                                  Symbol GPX6, GPX5p, GPXP3, GPx-6, GSHPx-6, dJ1186N24, dJ1186N24.1 Name (RefSeq) glutathione peroxidase 6   KO K00432   glutathione peroxidase [EC:1.11.1.9] Organism hsa  Homo sapiens (human) Pathway hsa00480   Glutathione metabolism hsa01100   Metabolic pathways hsa04918   Thyroid hormone synthesis hsa05014   Amyotrophic lateral sclerosis hsa05016   Huntington disease hsa05022   Pathways of neurodegeneration - multiple diseases Network nt06026  Glutathione biosynthesis nt06525  Ferroptosis   Element N01589   Glutathione biosynthesis Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09106 Metabolism of other amino acids    00480 Glutathione metabolism     257202 (GPX6)  09150 Organismal Systems   09152 Endocrine system    04918 Thyroid hormone synthesis     257202 (GPX6)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     257202 (GPX6)    05016 Huntington disease     257202 (GPX6)    05022 Pathways of neurodegeneration - multiple diseases     257202 (GPX6) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.11  Acting on a peroxide as acceptor    1.11.1  Peroxidases     1.11.1.9  glutathione peroxidase      257202 (GPX6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  GSHPx Motif Other DBs NCBI-GeneID:  257202 NCBI-ProteinID:  NP_874360 OMIM:  607913 HGNC:  4558 Ensembl:  ENSG00000198704 UniProt:  P59796 LinkDB All DBs Position 6:complement(28503296..28515793) Genome browser AA seq 221 aa AA seqDB search MFQQFQASCLVLFFLVGFAQQTLKPQNRKVDCNKGVTGTIYEYGALTLNGEEYIQFKQFA GKHVLFVNVAAYUGLAAQYPELNALQEELKNFGVIVLAFPCNQFGKQEPGTNSEILLGLK YVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKNSCPPTSDLLGSSSQLFWEPMKVHDIR WNFEKFLVGPDGVPVMHWFHQAPVSTVKSDILEYLKQFNTH NT seq 666 nt NT seq  +upstreamnt  +downstreamnt atgttccagcagttccaggcctcctgtcttgtcctgtttttcctggttggctttgctcag cagaccctaaagcctcaaaataggaaggtggattgcaacaaaggggtaacaggcaccatc tatgagtatggagccctcaccctcaacggcgaggagtacatccaattcaagcagtttgca ggcaagcacgtcctgtttgtcaatgtggccgcctattgaggcttggcagctcagtatcct gaactgaatgcactacaggaggagctgaagaattttggtgtcattgtgttggcctttccc tgcaaccagtttggaaaacaagaaccaggaacaaactcagaaatacttcttggtctcaag tatgtgtgtccaggtagtggctttgtccccagtttccagctctttgagaaaggggatgtg aatggagaaaaagaacagaaggtctttactttcctgaagaactcctgccctccgacctct gatcttttgggctcatcaagccaactcttctgggagcccatgaaggtccatgatatccgc tggaactttgagaaatttctggtggggcccgatggagtccctgtcatgcattggttccac caggctccagtcagcacagtcaagtcagacatcctggagtacctaaagcagttcaatacc cactag

Homo sapiens (human): 2882 Help Entry 2882              CDS       T01001                                  Symbol GPX7, CL683, GPX6, GPx-7, GSHPx-7, NPGPx Name (RefSeq) glutathione peroxidase 7   KO K00432   glutathione peroxidase [EC:1.11.1.9] Organism hsa  Homo sapiens (human) Pathway hsa00480   Glutathione metabolism hsa01100   Metabolic pathways hsa04918   Thyroid hormone synthesis hsa05014   Amyotrophic lateral sclerosis hsa05016   Huntington disease hsa05022   Pathways of neurodegeneration - multiple diseases Network nt06026  Glutathione biosynthesis nt06525  Ferroptosis   Element N01589   Glutathione biosynthesis Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09106 Metabolism of other amino acids    00480 Glutathione metabolism     2882 (GPX7)  09150 Organismal Systems   09152 Endocrine system    04918 Thyroid hormone synthesis     2882 (GPX7)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     2882 (GPX7)    05016 Huntington disease     2882 (GPX7)    05022 Pathways of neurodegeneration - multiple diseases     2882 (GPX7) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.11  Acting on a peroxide as acceptor    1.11.1  Peroxidases     1.11.1.9  glutathione peroxidase      2882 (GPX7) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  GSHPx AhpC-TSA Acyl-CoA_dh_C Redoxin Motif Other DBs NCBI-GeneID:  2882 NCBI-ProteinID:  NP_056511 OMIM:  615784 HGNC:  4559 Ensembl:  ENSG00000116157 UniProt:  Q96SL4 Structure PDB LinkDB All DBs Position 1:52602371..52609051 Genome browser AA seq 187 aa AA seqDB search MVAATVAAAWLLLWAAACAQQEQDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFT DQHYRALQQLQRDLGPHHFNVLAFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAV TGTGAHPAFKYLAQTSGKEPTWNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRKLI LLKREDL NT seq 564 nt NT seq  +upstreamnt  +downstreamnt atggtggcggcgacggtggcagcggcgtggctgctcctgtgggctgcggcctgcgcgcag caggagcaggacttctacgacttcaaggcggtcaacatccggggcaaactggtgtcgctg gagaagtaccgcggatcggtgtccctggtggtgaatgtggccagcgagtgcggcttcaca gaccagcactaccgagccctgcagcagctgcagcgagacctgggcccccaccactttaac gtgctcgccttcccctgcaaccagtttggccaacaggagcctgacagcaacaaggagatt gagagctttgcccgccgcacctacagtgtctcattccccatgtttagcaagattgcagtc accggtactggtgcccatcctgccttcaagtacctggcccagacttctgggaaggagccc acctggaacttctggaagtacctagtagccccagatggaaaggtggtaggggcttgggac ccaactgtgtcagtggaggaggtcagaccccagatcacagcgctcgtgaggaagctcatc ctactgaagcgagaagacttataa

Homo sapiens (human): 493869 Help Entry 493869            CDS       T01001                                  Symbol GPX8, EPLA847, GPx-8, GSHPx-8, UNQ847 Name (RefSeq) glutathione peroxidase 8 (putative)   KO K00432   glutathione peroxidase [EC:1.11.1.9] Organism hsa  Homo sapiens (human) Pathway hsa00480   Glutathione metabolism hsa01100   Metabolic pathways hsa04918   Thyroid hormone synthesis hsa05014   Amyotrophic lateral sclerosis hsa05016   Huntington disease hsa05022   Pathways of neurodegeneration - multiple diseases Network nt06026  Glutathione biosynthesis nt06525  Ferroptosis   Element N01589   Glutathione biosynthesis Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09106 Metabolism of other amino acids    00480 Glutathione metabolism     493869 (GPX8)  09150 Organismal Systems   09152 Endocrine system    04918 Thyroid hormone synthesis     493869 (GPX8)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     493869 (GPX8)    05016 Huntington disease     493869 (GPX8)    05022 Pathways of neurodegeneration - multiple diseases     493869 (GPX8) Enzymes [BR:hsa01000]  1. Oxidoreductases   1.11  Acting on a peroxide as acceptor    1.11.1  Peroxidases     1.11.1.9  glutathione peroxidase      493869 (GPX8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  GSHPx AhpC-TSA Redoxin DUF6693 Motif Other DBs NCBI-GeneID:  493869 NCBI-ProteinID:  NP_001008398 OMIM:  617172 HGNC:  33100 Ensembl:  ENSG00000164294 UniProt:  Q8TED1 Structure PDB LinkDB All DBs Position 5:55160171..55167297 Genome browser AA seq 209 aa AA seqDB search MEPLAAYPLKCSGPRAKVFAVLLSIVLCTVTLFLLQLKFLKPKINSFYAFEVKDAKGRTV SLEKYKGKVSLVVNVASDCQLTDRNYLGLKELHKEFGPSHFSVLAFPCNQFGESEPRPSK EVESFARKNYGVTFPIFHKIKILGSEGEPAFRFLVDSSKKEPRWNFWKYLVNPEGQVVKF WKPEEPIEVIRPDIAALVRQVIIKKKEDL NT seq 630 nt NT seq  +upstreamnt  +downstreamnt atggagcctcttgcagcttacccgctaaaatgttccgggcccagagcaaaggtatttgca gttttgctgtctatagttctatgcacagtaacgctatttcttctacaactaaaattcctc aaacctaaaatcaacagcttttatgcctttgaagtgaaggatgcaaaaggaagaactgtt tctctggaaaagtataaaggcaaagtttcactagttgtaaacgtggccagtgactgccaa ctcacagacagaaattacttagggctgaaggaactgcacaaagagtttggaccatcccac ttcagcgtgttggcttttccctgcaatcagtttggagaatcggagccccgcccaagcaag gaagtagaatcttttgcaagaaaaaactacggagtaactttccccatcttccacaagatt aagattctaggatctgaaggagaacctgcatttagatttcttgttgattcttcaaagaag gaaccaaggtggaatttttggaagtatcttgtcaaccctgagggtcaagttgtgaagttc tggaagccagaggagcccattgaagtcatcaggcctgacatagcagctctggttagacaa gtgatcataaaaaagaaagaggatctatga

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