KEGG   Homo sapiens (human): 29956
Entry
29956             CDS       T01001                                 
Symbol
CERS2, L3, LASS2, SP260, TMSG1
Name
(RefSeq) ceramide synthase 2
  KO
K24621  very-long-chain ceramide synthase [EC:2.3.1.297]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00600  Sphingolipid metabolism
hsa01100  Metabolic pathways
hsa04071  Sphingolipid signaling pathway
Module
hsa_M00094  Ceramide biosynthesis
hsa_M00099  Sphingosine biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    29956 (CERS2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    29956 (CERS2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.297  very-long-chain ceramide synthase
     29956 (CERS2)
SSDB
Motif
Pfam: TRAM_LAG1_CLN8 Homeodomain Homez Homeobox_KN
Other DBs
NCBI-GeneID: 29956
NCBI-ProteinID: NP_071358
OMIM: 606920
HGNC: 14076
Ensembl: ENSG00000143418
UniProt: Q96G23
LinkDB
Position
1:complement(150965186..150974835)
AA seq 380 aa
MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYV
ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR
RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY
WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD
SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF
GYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGEEAAAGGGA
KSRPLANGHPILNNNHRKND
NT seq 1143 nt   +upstreamnt  +downstreamnt
atgctccagaccttgtatgattacttctggtgggaacgtctgtggctgcctgtgaacttg
acctgggccgatctagaagaccgagatggacgtgtctacgccaaagcctcagatctctat
atcacgctgcccctggccttgctcttcctcatcgttcgatacttctttgagctgtacgtg
gctacaccactggctgccctcttgaacataaaggagaaaactcggctgcgggcacctccc
aacgccaccttggaacatttctacctgaccagtggcaagcagcccaagcaggtggaagta
gagcttttgtcccggcagagcgggctctctggccgccaggtagagcgttggttccgtcgc
cgccgcaaccaggaccggcccagtctcctcaagaagttccgagaagccagctggagattc
acattttacctgattgccttcattgccggcatggccgtcattgtggataaaccctggttc
tatgacatgaagaaagtttgggagggatatcccatacagagcactatcccttcccagtat
tggtactacatgattgaactttccttctactggtccctgctcttcagcattgcctctgat
gtcaagcgaaaggatttcaaggaacagatcatccaccatgtggccaccatcattctcatc
agcttttcctggtttgccaattacatccgagctgggactctaatcatggctctgcatgac
tcttccgattacctgctggagtcagccaagatgtttaactacgcgggatggaagaacacc
tgcaacaacatcttcatcgtcttcgccattgtttttatcatcacccgactggtcatcctg
cccttctggatcctgcattgcaccctggtgtacccactggagctctatcctgccttcttt
ggctattacttcttcaattccatgatgggagttctacagctgctgcatatcttctgggcc
tacctcattttgcgcatggcccacaagttcataactggaaagctggtagaagatgaacgc
agtgaccgggaagaaacagagagctcagagggggaggaggctgcagctgggggaggagca
aagagccggcccctagccaatggccaccccatcctcaataacaaccatcgtaagaatgac
tga

KEGG   Homo sapiens (human): 79603
Entry
79603             CDS       T01001                                 
Symbol
CERS4, LASS4, Trh1
Name
(RefSeq) ceramide synthase 4
  KO
K24621  very-long-chain ceramide synthase [EC:2.3.1.297]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00600  Sphingolipid metabolism
hsa01100  Metabolic pathways
hsa04071  Sphingolipid signaling pathway
Module
hsa_M00094  Ceramide biosynthesis
hsa_M00099  Sphingosine biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    79603 (CERS4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04071 Sphingolipid signaling pathway
    79603 (CERS4)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.297  very-long-chain ceramide synthase
     79603 (CERS4)
SSDB
Motif
Pfam: TRAM_LAG1_CLN8 Homeodomain Homeobox_KN
Other DBs
NCBI-GeneID: 79603
NCBI-ProteinID: NP_078828
OMIM: 615334
HGNC: 23747
Ensembl: ENSG00000090661
UniProt: Q9HA82 Q53HF9
LinkDB
Position
19:8209370..8262421
AA seq 394 aa
MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI
GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR
RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY
WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD
SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFF
GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPL
QLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT
NT seq 1185 nt   +upstreamnt  +downstreamnt
atgctgtccagtttcaacgagtggttttggcaggacaggttctggttaccacccaatgtc
acgtggacagagctagaagaccgggatggccgtgtctacccccacccccaggacttgttg
gcagccctgcccctggcgctggtcctcctggccatgcgccttgcctttgagagattcatt
ggcctgcccctgagccggtggctgggtgtgagggatcagaccaggaggcaagtgaagccc
aacgccacgctggagaaacacttcctcacggaagggcacaggcccaaggagccccagctg
tctctcctggccgcccagtgtggcctcacgctgcagcagacccagcgatggttccggaga
cgccggaaccaggatcgaccccagctgaccaagaagttctgtgaggccagctggaggttt
ctcttctacctgtcctccttcgtgggcggcctctcggtcctgtaccacgagtcatggctg
tgggcaccagtaatgtgctgggacaggtacccaaaccagactctgaagccatccctgtac
tggtggtacctcttggagctgggtttctacctctcactgctaatcaggctgccctttgat
gtcaagcgcaaggatttcaaggagcaggtgatacaccacttcgtggcggtcatcctgatg
accttctcctacagtgccaacctgctgcgcattggctctctggtgctgctgttacacgat
tcctctgactacctgctggaggcctgtaagatggtcaactacatgcagtatcagcaagtg
tgcgacgctctcttcctcatcttctcctttgtcttcttctacacccgactggtcctcttt
cccacccagatcctctacaccacatactacgagtccatcagcaacaggggccccttcttc
ggctactacttcttcaacgggcttctgatgttgctgcagctgctgcacgtgttctggtct
tgcctcattctgcgcatgctctatagcttcatgaagaagggccagatggagaaggacatt
cgtagtgatgtagaagaatcagactccagtgaggaggcggcggcggcccaggaacctctg
cagctaaagaacggggcagctggagggcccaggccagcccccactgatggccctcggagc
cgggtggccgggcgtctgaccaacaggcacacaacagccacatag

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