Homo sapiens (human): 29978
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Entry
29978 CDS
T01001
Symbol
UBQLN2, ALS15, CHAP1, DSK2, HRIHFB2157, N4BP4, PLIC2
Name
(RefSeq) ubiquilin 2
KO
K04523
ubiquilin
Organism
hsa
Homo sapiens (human)
Pathway
hsa04141
Protein processing in endoplasmic reticulum
hsa05014
Amyotrophic lateral sclerosis
Network
nt06464
Amyotrophic lateral sclerosis
nt06466
Pathways of neurodegeneration
Element
N01146
Mutation-inactivated UBQLN2 to 26S proteasome-mediated protein degradation
Disease
H00058
Amyotrophic lateral sclerosis (ALS)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
29978 (UBQLN2)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
29978 (UBQLN2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
29978 (UBQLN2)
03051 Proteasome [BR:
hsa03051
]
29978 (UBQLN2)
Membrane trafficking [BR:
hsa04131
]
Autophagy
Chaperone mediated autophagy (CMA)
Selective cargos
29978 (UBQLN2)
Proteasome [BR:
hsa03051
]
Eukaryotic proteasome
Proteasome interacting proteins (PIPs)
UBL-UBA shuttle proteins
29978 (UBQLN2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
UBQLN1
ubiquitin
STI1-HOP_DP
UBA
Rad60-SLD
YukD
UBA_7
Rad60-SLD_2
Ubiquitin_5
Dsc3_N
UBA_HOIP
ATG8
CUE
UBA_NBR1_C
Motif
Other DBs
NCBI-GeneID:
29978
NCBI-ProteinID:
NP_038472
OMIM:
300264
HGNC:
12509
Ensembl:
ENSG00000188021
UniProt:
Q9UHD9
Structure
PDB
PDBj
LinkDB
All DBs
Position
X:56563627..56567868
Genome browser
AA seq
624 aa
AA seq
DB search
MAENGESSGPPRPSRGPAAAQGSAAAPAEPKIIKVTVKTPKEKEEFAVPENSSVQQFKEA
ISKRFKSQTDQLVLIFAGKILKDQDTLIQHGIHDGLTVHLVIKSQNRPQGQSTQPSNAAG
TNTTSASTPRSNSTPISTNSNPFGLGSLGGLAGLSSLGLSSTNFSELQSQMQQQLMASPE
MMIQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHLLNNPDIMRQTLEIARN
PAMMQEMMRNQDLALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGNPFASVGSSSS
SGEGTQPSRTENRDPLPNPWAPPPATQSSATTSTTTSTGSGSGNSSSNATGNTVAAANYV
ASIFSTPGMQSLLQQITENPQLIQNMLSAPYMRSMMQSLSQNPDLAAQMMLNSPLFTANP
QLQEQMRPQLPAFLQQMQNPDTLSAMSNPRAMQALMQIQQGLQTLATEAPGLIPSFTPGV
GVGVLGTAIGPVGPVTPIGPIGPIVPFTPIGPIGPIGPTGPAAPPGSTGSGGPTGPTVSS
AAPSETTSPTSESGPNQQFIQQMVQALAGANAPQLPNPEVRFQQQLEQLNAMGFLNREAN
LQALIATGGDINAAIERLLGSQPS
NT seq
1875 nt
NT seq
+upstream
nt +downstream
nt
atggctgagaatggcgagagcagcggccccccgcgcccctcccgcggccctgctgcggcc
caaggctcggctgctgccccggctgagcctaaaatcatcaaagtcacggtgaagactccc
aaagagaaagaggagttcgcggtgcccgagaacagctcggttcagcagtttaaggaagcg
atttcgaaacgcttcaaatcccaaaccgatcagctagtgctgatttttgccggaaaaatc
ttaaaagatcaagataccttgatccagcatggcatccatgatgggctgactgttcacctt
gtcatcaaaagccagaaccgacctcagggccagtccacgcagcctagcaatgccgcggga
actaacactacctcggcgtcgactcccaggagtaactccacacctatttccacaaatagc
aacccgtttgggttggggagcctgggaggacttgcaggccttagcagcctgggcttgagc
tcgaccaacttctctgagctccagagccagatgcagcagcagcttatggccagccctgag
atgatgatccaaataatggaaaatccctttgttcagagcatgctttcgaatcccgatctg
atgaggcagctcattatggctaatccacagatgcagcaattgattcagagaaacccagaa
atcagtcacctgctcaacaacccagacataatgaggcagacactcgaaattgccaggaat
ccagccatgatgcaagagatgatgagaaatcaagacctggctcttagcaatctagaaagc
atcccaggtggctataatgctttacggcgcatgtacactgacattcaagagccgatgctg
aatgccgcacaagagcagtttgggggtaatccatttgcctccgtggggagtagttcctcc
tctggggaaggtacgcagccttcccgcacagaaaatcgcgatccactacccaatccatgg
gcaccaccgccagctacccagagttctgcaactaccagcacgaccacaagcactggtagt
gggtctggcaatagttccagcaatgctactgggaacaccgttgctgccgctaattatgtc
gccagcatctttagtaccccaggcatgcagagcctgctgcaacagataactgaaaacccc
cagctgattcagaatatgctgtcggcgccctacatgagaagcatgatgcagtcgctgagc
cagaatccagatttggctgcacagatgatgctgaatagcccgctgtttactgcaaatcct
cagctgcaggagcagatgcggccacagctcccagccttcctgcagcagatgcagaatcca
gacacactatcagccatgtcaaacccaagagcaatgcaggctttaatgcagatccagcag
gggctacagacattagccactgaagcacctggcctgattccgagcttcactccaggtgtg
ggggtgggggtgctgggaaccgctataggccctgtaggcccagtcacccccataggcccc
ataggccctatagtcccttttacccccataggccccattgggcccataggacccactggc
cctgcagccccccctggctccaccggctctggtggccccacggggcctactgtgtccagc
gctgcacctagtgaaaccacgagtcctacatcagaatctggacccaaccagcagttcatt
cagcaaatggtgcaggccctggctggagcaaatgctccacagctgccgaatccagaagtc
agatttcagcaacaactggaacagctcaacgcaatggggttcttaaaccgtgaagcaaac
ttgcaggccctaatagcaacaggaggcgacatcaatgcagccattgaaaggctgctgggc
tcccagccatcgtaa
DBGET
integrated database retrieval system
