Homo sapiens (human): 3061 Help Entry 3061              CDS       T01001                                  Symbol HCRTR1, ORXR1, OX1R, OXR1 Name (RefSeq) hypocretin receptor 1   KO K04238   hypocretin (orexin) receptor 1 Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction Network nt06325  Hormone/cytokine signaling   Element N01794   HCRT-HCRTR signaling pathway Drug target Almorexant:  D09964 Daridorexant (DG03119):  D11886 D11887<US> Filorexant:  D10345 Lemborexant:  D11022<JP/US> Suvorexant:  D10082<JP/US> Vornorexant hydrate:  D12611 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3061 (HCRTR1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3061 (HCRTR1) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Orexin     3061 (HCRTR1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srw 7tm_4 Orexin_rec2 SteA-like_C Form_Nir_trans Motif Other DBs NCBI-GeneID:  3061 NCBI-ProteinID:  NP_001516 OMIM:  602392 HGNC:  4848 Ensembl:  ENSG00000121764 UniProt:  O43613 Structure PDB LinkDB All DBs Position 1:31617689..31634492 Genome browser AA seq 425 aa AA seqDB search MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV TTVLP NT seq 1278 nt NT seq  +upstreamnt  +downstreamnt atggagccctcagccaccccaggggcccagatgggggtcccccctggcagcagagagccg tcccctgtgcctccagactatgaagatgagtttctccgctatctgtggcgcgattatctg tacccaaaacagtatgagtgggtcctcatcgcagcctatgtggctgtgttcgtcgtggcc ctggtgggcaacacgctggtctgcctggccgtgtggcggaaccaccacatgaggacagtc accaactacttcattgtcaacctgtccctggctgacgttctggtgactgctatctgcctg ccggccagcctgctggtggacatcactgagtcctggctgttcggccatgccctctgcaag gtcatcccctatctacaggctgtgtccgtgtcagtggcagtgctaactctcagcttcatc gccctggaccgctggtatgccatctgccacccactattgttcaagagcacagcccggcgg gcccgtggctccatcctgggcatctgggctgtgtcgctggccatcatggtgccccaggct gcagtcatggaatgcagcagtgtgctgcctgagctagccaaccgcacacggctcttctca gtctgtgatgaacgctgggcagatgacctctatcccaagatctaccacagttgcttcttt attgtcacctacctggccccactgggcctcatggccatggcctatttccagatattccgc aagctctggggccgccagatccccggcaccacctcagcactggtgcggaactggaagcgc ccctcagaccagctgggggacctggagcagggcctgagtggagagccccagccccgggcc cgcgccttcctggctgaagtgaagcagatgcgtgcacggaggaagacagccaagatgctg atggtggtgctgctggtcttcgccctctgctacctgcccatcagcgtcctcaatgtcctt aagagggtgttcgggatgttccgccaagccagtgaccgcgaagctgtctacgcctgcttc accttctcccactggctggtgtacgccaacagcgctgccaaccccatcatctacaacttc ctcagtggcaaattccgggagcagtttaaggctgccttctcctgctgcctgcctggcctg ggtccctgcggctctctgaaggcccctagtccccgctcctctgccagccacaagtccttg tccttgcagagccgatgctccatctccaaaatctctgagcatgtggtgctcaccagcgtc accacagtgctgccctga

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