Homo sapiens (human): 3350 Help Entry 3350              CDS       T01001                                  Symbol HTR1A, 5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD Name (RefSeq) 5-hydroxytryptamine receptor 1A   KO K04153   5-hydroxytryptamine receptor 1 Organism hsa  Homo sapiens (human) Pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04726   Serotonergic synapse hsa04742   Taste transduction Network nt06544  Neuroactive ligand signaling   Element N01901   Serotonin-HTR1/5-GNAI/O signaling pathway Disease H02773   Menstrual cycle-dependent periodic fever Drug target Adatanserin hydrochloride:  D02767 Aripiprazole (DG00906):  D01164<JP/US> D10355 D10364<US> D10516<JP/US> Asenapine (DG03100):  D02995<JP/US> Bifeprunox (DG01304):  D06566 D06567 Binospirone mesylate:  D03121 Brexpiprazole (DG03365):  D10309<JP/US> D13183 Buspirone (DG00913):  D00702<US> D07593 Cariprazine (DG01305):  D09876<US> D09997 Cinitapride (DG01520):  D07700 D07701 Cyproheptadine (DG01109):  D02234<JP/US> D07765 Eptapirone:  D02576 Ergot alkaloids:  D07906 Ergotamine (DG00834):  D00679<US> Flesinoxan:  D02568 Flibanserin:  D02577<US> Gepirone:  D04314 Indorenate hydrochloride:  D04533 Ipsapirone hydrochloride:  D04611 Lecozotan hydrochloride:  D04683 Methysergide (DG00835):  D00681 D02357 Naluzotan (DG01279):  D09358 D09359 Pardoprunox (DG01324):  D09366 D09397 Pipotiazine (DG00884):  D02680 D08385 Pizotifen (DG00842):  D05523 D08397 Sarizotan hydrochloride:  D05804 Sunepitron hydrochloride:  D02569 Tandospirone (DG01306):  D01992<JP> D08561 Tiospirone hydrochloride:  D02688 Ulotaront (DG03247):  D12474 D12475 Vilazodone (DG00964):  D09698 D09699<US> Vortioxetine (DG00965):  D10184 D10185<JP/US> D12544 Xaliproden (DG01008):  D01537 D06327 Zalospirone hydrochloride:  D06354 Zotepine:  D01321<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04024 cAMP signaling pathway     3350 (HTR1A)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3350 (HTR1A)    04082 Neuroactive ligand signaling     3350 (HTR1A)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3350 (HTR1A)   09157 Sensory system    04742 Taste transduction     3350 (HTR1A)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3350 (HTR1A) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3350 (HTR1A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx Motif Other DBs NCBI-GeneID:  3350 NCBI-ProteinID:  NP_000515 OMIM:  109760 HGNC:  5286 Ensembl:  ENSG00000178394 UniProt:  P08908 Q5ZGX3 A8K5W4 Structure PDBPDBj LinkDB All DBs Position 5:complement(63957874..63962445) Genome browser AA seq 422 aa AA seqDB search MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAA IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED RSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADT RHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN SKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLP FFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC RQ NT seq 1269 nt NT seq  +upstreamnt  +downstreamnt atggatgtgctcagccctggtcagggcaacaacaccacatcaccaccggctccctttgag accggcggcaacactactggtatctccgacgtgaccgtcagctaccaagtgatcacctct ctgctgctgggcacgctcatcttctgcgcggtgctgggcaatgcgtgcgtggtggctgcc atcgccttggagcgctccctgcagaacgtggccaattatcttattggctctttggcggtc accgacctcatggtgtcggtgttggtgctgcccatggccgcgctgtatcaggtgctcaac aagtggacactgggccaggtaacctgcgacctgttcatcgccctcgacgtgctgtgctgc acctcatccatcttgcacctgtgcgccatcgcgctggacaggtactgggccatcacggac cccatcgactacgtgaacaagaggacgccccggcgcgccgctgcgctcatctcgctcact tggcttattggcttcctcatctctatcccgcccatgctgggctggcgcaccccggaagac cgctcggaccccgacgcatgcaccattagcaaggatcatggctacactatctattccacc tttggagctttctacatcccgctgctgctcatgctggttctctatgggcgcatattccga gctgcgcgcttccgcatccgcaagacggtcaaaaaggtggagaagaccggagcggacacc cgccatggagcatctcccgccccgcagcccaagaagagtgtgaatggagagtcggggagc aggaactggaggctgggcgtggagagcaaggctgggggtgctctgtgcgccaatggcgcg gtgaggcaaggtgacgatggcgccgccctggaggtgatcgaggtgcaccgagtgggcaac tccaaagagcacttgcctctgcccagcgaggctggtcctaccccttgtgcccccgcctct ttcgagaggaaaaatgagcgcaacgccgaggcgaagcgcaagatggccctggcccgagag aggaagacagtgaagacgctgggcatcatcatgggcaccttcatcctctgctggctgccc ttcttcatcgtggctcttgttctgcccttctgcgagagcagctgccacatgcccaccctg ttgggcgccataatcaattggctgggctactccaactctctgcttaaccccgtcatttac gcatacttcaacaaggactttcaaaacgcgtttaagaagatcattaagtgtaagttctgc cgccagtga

Homo sapiens (human): 3351 Help Entry 3351              CDS       T01001                                  Symbol HTR1B, 5-HT-1B, 5-HT-1D-beta, 5-HT1B, 5-HT1DB, HTR1D2, HTR1DB, S12 Name (RefSeq) 5-hydroxytryptamine receptor 1B   KO K04153   5-hydroxytryptamine receptor 1 Organism hsa  Homo sapiens (human) Pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04726   Serotonergic synapse hsa04742   Taste transduction Network nt06544  Neuroactive ligand signaling   Element N01901   Serotonin-HTR1/5-GNAI/O signaling pathway Drug target Almotriptan (DG00839):  D02824 D02825<US> Alniditan dihydrochloride:  D02826 Avitriptan fumarate:  D03014 Cinitapride (DG01520):  D07700 D07701 Cyproheptadine (DG01109):  D02234<JP/US> D07765 Dihydroergotamine (DG00833):  D02211<US> D07837 D07838 Eletriptan (DG00840):  D01973<JP/US> D07887 D11617 Elzasonan (DG01314):  D03982 D03983 Ergot alkaloids:  D07906 Ergotamine (DG00834):  D00679<US> Frovatriptan (DG00841):  D04264<US> D07997 Indorenate hydrochloride:  D04533 Naratriptan (DG00837):  D00674<JP/US> D08255 Pizotifen (DG00842):  D05523 D08397 Rizatriptan (DG00838):  D00675<JP/US> D05740 D08485 Sumatriptan (DG00836):  D00451<JP/US> D00676<JP/US> Zolmitriptan:  D00415<JP/US> Zotepine:  D01321<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04024 cAMP signaling pathway     3351 (HTR1B)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3351 (HTR1B)    04082 Neuroactive ligand signaling     3351 (HTR1B)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3351 (HTR1B)   09157 Sensory system    04742 Taste transduction     3351 (HTR1B)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3351 (HTR1B) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3351 (HTR1B) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srx 7tm_4 Motif Other DBs NCBI-GeneID:  3351 NCBI-ProteinID:  NP_000854 OMIM:  182131 HGNC:  5287 Ensembl:  ENSG00000135312 UniProt:  P28222 X5D7I5 A8K215 Structure PDBPDBj LinkDB All DBs Position 6:complement(77460924..77463491) Genome browser AA seq 390 aa AA seqDB search MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALIT LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL KQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLE KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYL NSLINPIIYTMSNEDFKQAFHKLIRFKCTS NT seq 1173 nt NT seq  +upstreamnt  +downstreamnt atggaggaaccgggtgctcagtgcgctccaccgccgcccgcgggctccgagacctgggtt cctcaagccaacttatcctctgctccctcccaaaactgcagcgccaaggactacatttac caggactccatctccctaccctggaaagtactgctggttatgctattggcgctcatcacc ttggccaccacgctctccaatgcctttgtgattgccacagtgtaccggacccggaaactg cacaccccggctaactacctgatcgcctctctggcggtcaccgacctgcttgtgtccatc ctggtgatgcccatcagcaccatgtacactgtcaccggccgctggacactgggccaggtg gtctgtgacttctggctgtcgtcggacatcacttgttgcactgcctccatcctgcacctc tgtgtcatcgccctggaccgctactgggccatcacggacgccgtggagtactcagctaaa aggactcccaagagggcggcggtcatgatcgcgctggtgtgggtcttctccatctctatc tcgctgccgcccttcttctggcgtcaggctaaggccgaagaggaggtgtcggaatgcgtg gtgaacaccgaccacatcctctacacggtctactccacggtgggtgctttctacttcccc accctgctcctcatcgccctctatggccgcatctacgtagaagcccgctcccggattttg aaacagacgcccaacaggaccggcaagcgcttgacccgagcccagctgataaccgactcc cccgggtccacgtcctcggtcacctctattaactcgcgggttcccgacgtgcccagcgaa tccggatctcctgtgtatgtgaaccaagtcaaagtgcgagtctccgacgccctgctggaa aagaagaaactcatggccgctagggagcgcaaagccaccaagaccctagggatcattttg ggagcctttattgtgtgttggctacccttcttcatcatctccctagtgatgcctatctgc aaagatgcctgctggttccacctagccatctttgacttcttcacatggctgggctatctc aactccctcatcaaccccataatctataccatgtccaatgaggactttaaacaagcattc cataaactgatacgttttaagtgcacaagttga

Homo sapiens (human): 3352 Help Entry 3352              CDS       T01001                                  Symbol HTR1D, 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4 Name (RefSeq) 5-hydroxytryptamine receptor 1D   KO K04153   5-hydroxytryptamine receptor 1 Organism hsa  Homo sapiens (human) Pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04726   Serotonergic synapse hsa04742   Taste transduction Network nt06544  Neuroactive ligand signaling   Element N01901   Serotonin-HTR1/5-GNAI/O signaling pathway Drug target Almotriptan (DG00839):  D02824 D02825<US> Alniditan dihydrochloride:  D02826 Avitriptan fumarate:  D03014 Cinitapride (DG01520):  D07700 D07701 Cyproheptadine (DG01109):  D02234<JP/US> D07765 Dihydroergotamine (DG00833):  D02211<US> D07837 D07838 Eletriptan (DG00840):  D01973<JP/US> D07887 D11617 Elzasonan (DG01314):  D03982 D03983 Ergot alkaloids:  D07906 Ergotamine (DG00834):  D00679<US> Fenfluramine (DG00103):  D04148<JP/US> D07945 Frovatriptan (DG00841):  D04264<US> D07997 Indorenate hydrochloride:  D04533 Naratriptan (DG00837):  D00674<JP/US> D08255 Pizotifen (DG00842):  D05523 D08397 Rizatriptan (DG00838):  D00675<JP/US> D05740 D08485 Sumatriptan (DG00836):  D00451<JP/US> D00676<JP/US> Zolmitriptan:  D00415<JP/US> Zotepine:  D01321<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04024 cAMP signaling pathway     3352 (HTR1D)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3352 (HTR1D)    04082 Neuroactive ligand signaling     3352 (HTR1D)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3352 (HTR1D)   09157 Sensory system    04742 Taste transduction     3352 (HTR1D)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3352 (HTR1D) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3352 (HTR1D) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx Motif Other DBs NCBI-GeneID:  3352 NCBI-ProteinID:  NP_000855 OMIM:  182133 HGNC:  5289 Ensembl:  ENSG00000179546 UniProt:  P28221 Structure PDBPDBj LinkDB All DBs Position 1:complement(23191895..23217502) Genome browser AA seq 377 aa AA seqDB search MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVL TTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDIT CCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAK AQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFT TAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKAT KILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFN EEFRQAFQKIVPFRKAS NT seq 1134 nt NT seq  +upstreamnt  +downstreamnt atgtccccactgaaccagtcagcagaaggccttccccaggaggcctccaacagatccctg aatgccacagaaacctcagaggcttgggatcccaggaccctccaggcgctcaagatctcc cttgccgtggtcctttccgtcatcacactggccacagtcctctccaatgcctttgtactc accaccatcttactcaccaggaagctccacacccctgccaactacctgattggctccctg gccaccaccgacctcttggtttccatcttggtaatgcccatcagcatcgcctataccatc acccacacctggaactttggccaaatcttgtgtgacatctggctgtcctctgacatcacg tgctgcacagcctccatcctgcatctctgtgtcattgctctggacaggtactgggcaatc acagatgccctggaatacagtaaacgcaggacggctggccacgcggccaccatgatcgcc attgtctgggccatctccatctgcatctccatccccccgctcttctggcggcaggccaag gcccaggaggagatgtcggactgtctggtgaacacctctcagatctcctacaccatctac tccacctgtggggccttctacattccctcggtgttgctcatcatcctatatggccggatc taccgggctgcccggaaccgcatcctgaatccaccctcactctatgggaagcgcttcacc acggcccacctcatcacaggctctgccgggtcctcgctctgctcgctcaactccagcctc catgaggggcactcgcactcggctggctcccctctctttttcaaccacgtgaaaatcaag cttgctgacagtgccctggaacgcaagaggatttctgctgctcgagaaaggaaagccact aaaatcctgggcatcattctgggggcctttatcatctgctggctgcccttcttcgtggtg tctctggtcctccccatctgccgggactcctgctggatccacccggcgctctttgacttc ttcacctggctaggctatttaaactccctcatcaatccaataatctacactgtgtttaat gaagagtttcggcaagcttttcagaaaattgtccctttccggaaggcctcctag

Homo sapiens (human): 3354 Help Entry 3354              CDS       T01001                                  Symbol HTR1E, 5-HT1E Name (RefSeq) 5-hydroxytryptamine receptor 1E   KO K04153   5-hydroxytryptamine receptor 1 Organism hsa  Homo sapiens (human) Pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04726   Serotonergic synapse hsa04742   Taste transduction Network nt06544  Neuroactive ligand signaling   Element N01901   Serotonin-HTR1/5-GNAI/O signaling pathway Drug target Cinitapride (DG01520):  D07700 D07701 Cyproheptadine (DG01109):  D02234<JP/US> D07765 Indorenate hydrochloride:  D04533 Pizotifen (DG00842):  D05523 D08397 Zotepine:  D01321<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04024 cAMP signaling pathway     3354 (HTR1E)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3354 (HTR1E)    04082 Neuroactive ligand signaling     3354 (HTR1E)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3354 (HTR1E)   09157 Sensory system    04742 Taste transduction     3354 (HTR1E)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3354 (HTR1E) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3354 (HTR1E) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srx 7TM_GPCR_Srsx 7tm_4 Motif Other DBs NCBI-GeneID:  3354 NCBI-ProteinID:  NP_000856 OMIM:  182132 HGNC:  5291 Ensembl:  ENSG00000168830 UniProt:  P28566 Structure PDBPDBj LinkDB All DBs Position 6:86937528..87016679 Genome browser AA seq 365 aa AA seqDB search MNITNCTTEASMAIRPKTITEKMLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYL ICSLAVTDLLVAVLVMPLSIIYIVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDR YWAITNAIEYARKRTAKRAALMILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQHDHV IYTIYSTLGAFYIPLTLILILYYRIYHAAKSLYQKRGSSRHLSNRSTDSQNSFASCKLTQ TFCVSDFSTSDPTTEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAF ILSWLPFFIKELIVGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIR CREHT NT seq 1098 nt NT seq  +upstreamnt  +downstreamnt atgaacatcacaaactgtaccacagaggccagcatggctataagacccaagaccatcact gagaagatgctcatttgcatgactctggtggtcatcaccaccctcaccacgttgctgaac ttggctgtgatcatggctattggcaccaccaagaagctccaccagcctgccaactaccta atctgttctctggccgtgacggacctcctggtggcagtgctcgtcatgcccctgagcatc atctacattgtcatggatcgctggaagcttgggtacttcctctgtgaggtgtggctgagt gtggacatgacctgctgcacctgctccatcctccacctctgtgtcattgccctggacagg tactgggccatcaccaatgctattgaatacgccaggaagaggacggccaagagggccgcg ctgatgatccttaccgtctggaccatctccattttcatctccatgccccctctgttctgg agaagccaccgccgcctaagccctccccctagtcagtgcaccatccagcacgaccatgtt atctacaccatttactccacgctgggtgcgttttatatccccttgactttgatactgatt ctctattaccggatttaccacgcggccaagagcctttaccagaaaaggggatcaagtcgg cacttaagcaacagaagcacagatagccagaattcttttgcaagttgtaaacttacacag actttctgtgtgtctgacttctccacctcagaccctaccacagagtttgaaaagttccat gcctccatcaggatcccccccttcgacaatgatctagatcacccaggagaacgtcagcag atctctagcaccagggaacggaaggcagcacgcatcctggggctgattctgggtgcattc attttatcctggctgccatttttcatcaaagagttgattgtgggtctgagcatctacacc gtgtcctcggaagtggccgactttctgacgtggctcggttatgtgaattctctgatcaac cctctgctctatacgagttttaatgaagactttaagctggcttttaaaaagctcattaga tgccgagagcatacttag

Homo sapiens (human): 3355 Help Entry 3355              CDS       T01001                                  Symbol HTR1F, 5-HT-1F, 5-HT1F, 5HT6, HTR1EL, MR77 Name (RefSeq) 5-hydroxytryptamine receptor 1F   KO K04153   5-hydroxytryptamine receptor 1 Organism hsa  Homo sapiens (human) Pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04726   Serotonergic synapse hsa04742   Taste transduction Network nt06544  Neuroactive ligand signaling   Element N01901   Serotonin-HTR1/5-GNAI/O signaling pathway Drug target Cinitapride (DG01520):  D07700 D07701 Cyproheptadine (DG01109):  D02234<JP/US> D07765 Indorenate hydrochloride:  D04533 Lasmiditan (DG01332):  D10338 D10424<JP/US> Pizotifen (DG00842):  D05523 D08397 Zotepine:  D01321<JP> Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04024 cAMP signaling pathway     3355 (HTR1F)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3355 (HTR1F)    04082 Neuroactive ligand signaling     3355 (HTR1F)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3355 (HTR1F)   09157 Sensory system    04742 Taste transduction     3355 (HTR1F)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3355 (HTR1F) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3355 (HTR1F) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srv 7TM_GPCR_Srx 7tm_4 Glycoprotein_G Motif Other DBs NCBI-GeneID:  3355 NCBI-ProteinID:  NP_000857 OMIM:  182134 HGNC:  5292 Ensembl:  ENSG00000179097 UniProt:  P30939 Structure PDBPDBj LinkDB All DBs Position 3:87792706..87993839 Genome browser AA seq 366 aa AA seqDB search MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK LVRCRC NT seq 1101 nt NT seq  +upstreamnt  +downstreamnt atggatttcttaaattcatctgatcaaaacttgacctcagaggaactgttaaacagaatg ccatccaaaattctggtgtccctcactctgtctgggctggcactgatgacaacaactatc aactcccttgtgatcgctgcaattattgtgacccggaagctgcaccatccagccaattat ttaatttgttcccttgcagtcacagattttcttgtggctgtcctggtgatgcccttcagc attgtgtatattgtgagagagagctggattatggggcaagtggtctgtgacatttggctg agtgttgacattacctgctgcacgtgctccatcttgcatctctcagctatagctttggat cggtatcgagcaatcacagatgctgttgagtatgccaggaaaaggactccaaagcatgct ggcattatgattacaatagtttggattatatctgtttttatctctatgcctcctctattc tggaggcaccaaggaactagcagagatgatgaatgcatcatcaagcacgaccacattgtt tccaccatttactcaacatttggagctttctacatcccactggcattgattttgatcctt tactacaaaatatatagagcagcaaagacattataccacaagagacaagcaagtaggatt gcaaaggaggaggtgaatggccaagtccttttggagagtggtgagaaaagcactaaatca gtttccacatcctatgtactagaaaagtctttatctgacccatcaacagactttgataaa attcatagcacagtgagaagtctcaggtctgaattcaagcatgagaaatcttggagaagg caaaagatctcaggtacaagagaacggaaagcagccactaccctgggattaatcttgggt gcatttgtaatatgttggcttcctttttttgtaaaagaattagttgttaatgtctgtgac aaatgtaaaatttctgaagaaatgtccaattttttggcatggcttgggtatctcaattcc cttataaatccactgatttacacaatctttaatgaagacttcaagaaagcattccaaaag cttgtgcgatgtcgatgttag

Homo sapiens (human): 3356 Help Entry 3356              CDS       T01001                                  Symbol HTR2A, 5-HT2A, HTR2 Name (RefSeq) 5-hydroxytryptamine receptor 2A   KO K04157   5-hydroxytryptamine receptor 2 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04540   Gap junction hsa04726   Serotonergic synapse hsa04750   Inflammatory mediator regulation of TRP channels Network nt06528  Calcium signaling nt06544  Neuroactive ligand signaling   Element N01640   GPCR-PLCB-ITPR signaling pathway N01900   Serotonin-HTR2-GNAQ/11 signaling pathway Disease H01450   Obsessive-compulsive disorder H01611   Alcohol dependence H01646   Major depressive disorder H01649   Schizophrenia Drug target Adatanserin hydrochloride:  D02767 Altanserin tartrate:  D02836 Amesergide:  D02893 Aripiprazole (DG00906):  D01164<JP/US> D10355 D10364<US> D10516<JP/US> Asenapine (DG03100):  D02995<JP/US> D11769<US> Atiprosin maleate:  D03005 Blonanserin:  D01176<JP> Brexpiprazole (DG03365):  D10309<JP/US> D13183 Brolamfetamine:  D12707 Cariprazine (DG01305):  D09876<US> D09997 Chlorpromazine (DG00867):  D00270 D00789<JP/US> D03274 D04034<JP> D09819 Cinitapride (DG01520):  D07700 D07701 Cisapride (DG00056):  D00274 D02092 Clozapine:  D00283<JP/US> Cyamemazine (DG00872):  D07307 D07756 Cyproheptadine (DG01109):  D02234<JP/US> D07765 Deupsilocin (DG03354):  D13135 D13136 Dimethyltryptamine:  D13141 Dimetotiazine (DG00843):  D01902<JP> D07854 Eplivanserin:  D10006 Esmirtazapine maleate:  D04055 Fananserin:  D02656 Fenfluramine (DG00103):  D04148<JP/US> D07945 Flibanserin:  D02577<US> Glemanserin:  D04320 Iloperidone:  D02666<US> Ketanserin (DG00265):  D02363 D08099 Loxapine (DG00897):  D00794<US> D02340 D08148 Lubazodone hydrochloride:  D04788 Lumateperone (DG02937):  D11169 D11170<US> Lurasidone:  D04820<JP/US> Mesoridazine (DG00883):  D00795 D02671 Methysergide (DG00835):  D00681 D02357 Metrenperone:  D05015 Mianserin (DG00951):  D01358<JP> D08216 Milsaperidone:  D13099 Mirtazapine (DG02838):  D00563<JP/US> D11056 Mosapramine (DG00905):  D01548<JP> D08235 Naftidrofuryl (DG00290):  D05107 D08244 Nefazodone (DG00953):  D00819<US> D08257 Nelotanserin:  D09645 Ocaperidone:  D02675 Olanzapine (DG00898):  D00454<JP/US> D06623<US> Opipramol (DG00930):  D01477 D08297 Paliperidone (DG00907):  D05339<JP/US> D05340<JP/US> Pelanserin hydrochloride:  D05395 Periciazine:  D01485<JP> Perospirone hydrochloride hydrate:  D02372<JP> Pimavanserin:  D08969<US> Pipotiazine (DG00884):  D02680 D08385 Pizotifen (DG00842):  D05523 D08397 Pruvanserin (DG01278):  D06632 D06633 Psilocybin:  D12881 Quetiapine (DG00899):  D00458<JP/US> D08456 Risperidone:  D00426<JP/US> Ritanserin:  D05738 Sarpogrelate (DG01333):  D01624<JP> D08508 Sergolexole maleate:  D05829 Sertindole:  D00561 Setoperone:  D02686 Temanogrel (DG01334):  D09976 D09977 Tiospirone hydrochloride:  D02688 Trazodone (DG00952):  D00820<JP/US> D08626 Tropanserin hydrochloride:  D06253 Xylamidine tosylate:  D06343 Zicronapine (DG01539):  D10329 D10495 Ziprasidone (DG00892):  D01939<US> D02100<US> D08687 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     3356 (HTR2A)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3356 (HTR2A)    04082 Neuroactive ligand signaling     3356 (HTR2A)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     3356 (HTR2A)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3356 (HTR2A)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     3356 (HTR2A)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3356 (HTR2A) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3356 (HTR2A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx ATG33 Motif Other DBs NCBI-GeneID:  3356 NCBI-ProteinID:  NP_000612 OMIM:  182135 HGNC:  5293 Ensembl:  ENSG00000102468 UniProt:  P28223 Structure PDBPDBj LinkDB All DBs Position 13:complement(46831546..46898082) Genome browser AA seq 471 aa AA seqDB search MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV NT seq 1416 nt NT seq  +upstreamnt  +downstreamnt atggatattctttgtgaagaaaatacttctttgagctcaactacgaactccctaatgcaa ttaaatgatgacaccaggctctacagtaatgactttaactccggagaagctaacacttct gatgcatttaactggacagtcgactctgaaaatcgaaccaacctttcctgtgaagggtgc ctctcaccgtcgtgtctctccttacttcatctccaggaaaaaaactggtctgctttactg acagccgtagtgattattctaactattgctggaaacatactcgtcatcatggcagtgtcc ctagagaaaaagctgcagaatgccaccaactatttcctgatgtcacttgccatagctgat atgctgctgggtttccttgtcatgcccgtgtccatgttaaccatcctgtatgggtaccgg tggcctctgccgagcaagctttgtgcagtctggatttacctggacgtgctcttctccacg gcctccatcatgcacctctgcgccatctcgctggaccgctacgtcgccatccagaatccc atccaccacagccgcttcaactccagaactaaggcatttctgaaaatcattgctgtttgg accatatcagtaggtatatccatgccaataccagtctttgggctacaggacgattcgaag gtctttaaggaggggagttgcttactcgccgatgataactttgtcctgatcggctctttt gtgtcatttttcattcccttaaccatcatggtgatcacctactttctaactatcaagtca ctccagaaagaagctactttgtgtgtaagtgatcttggcacacgggccaaattagcttct ttcagcttcctccctcagagttctttgtcttcagaaaagctcttccagcggtcgatccat agggagccagggtcctacacaggcaggaggactatgcagtccatcagcaatgagcaaaag gcatgcaaggtgctgggcatcgtcttcttcctgtttgtggtgatgtggtgccctttcttc atcacaaacatcatggccgtcatctgcaaagagtcctgcaatgaggatgtcattggggcc ctgctcaatgtgtttgtttggatcggttatctctcttcagcagtcaacccactagtctac acactgttcaacaagacctataggtcagccttttcacggtatattcagtgtcagtacaag gaaaacaaaaaaccattgcagttaattttagtgaacacaataccggctttggcctacaag tctagccaacttcaaatgggacaaaaaaagaattcaaagcaagatgccaagacaacagat aatgactgctcaatggttgctctaggaaagcagcattctgaagaggcttctaaagacaat agcgacggagtgaatgaaaaggtgagctgtgtgtga

Homo sapiens (human): 3357 Help Entry 3357              CDS       T01001                                  Symbol HTR2B, 5-HT(2B), 5-HT-2B, 5-HT2B Name (RefSeq) 5-hydroxytryptamine receptor 2B   KO K04157   5-hydroxytryptamine receptor 2 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04540   Gap junction hsa04726   Serotonergic synapse hsa04750   Inflammatory mediator regulation of TRP channels Network nt06528  Calcium signaling nt06544  Neuroactive ligand signaling   Element N01640   GPCR-PLCB-ITPR signaling pathway N01900   Serotonin-HTR2-GNAQ/11 signaling pathway Drug target Adatanserin hydrochloride:  D02767 Brolamfetamine:  D12707 Chlorpromazine (DG00867):  D00270 D00789<JP/US> D03274 D04034<JP> D09819 Cinitapride (DG01520):  D07700 D07701 Cyproheptadine (DG01109):  D02234<JP/US> D07765 Dimetotiazine (DG00843):  D01902<JP> D07854 Flibanserin:  D02577<US> Glemanserin:  D04320 Iloperidone:  D02666<US> Methysergide (DG00835):  D00681 D02357 Metrenperone:  D05015 Milsaperidone:  D13099 Mirtazapine (DG02838):  D00563<JP/US> D11056 Ocaperidone:  D02675 Olanzapine (DG00898):  D00454<JP/US> D06623<US> Opipramol (DG00930):  D01477 D08297 Pelanserin hydrochloride:  D05395 Periciazine:  D01485<JP> Pizotifen (DG00842):  D05523 D08397 Sergolexole maleate:  D05829 Setoperone:  D02686 Tiospirone hydrochloride:  D02688 Trazodone (DG00952):  D00820<JP/US> D08626 Tropanserin hydrochloride:  D06253 Xylamidine tosylate:  D06343 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     3357 (HTR2B)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3357 (HTR2B)    04082 Neuroactive ligand signaling     3357 (HTR2B)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     3357 (HTR2B)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3357 (HTR2B)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     3357 (HTR2B)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3357 (HTR2B) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3357 (HTR2B) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srv 7tm_4 DUF7893 CfpA_N 7TM_GPCR_Srx Motif Other DBs NCBI-GeneID:  3357 NCBI-ProteinID:  NP_000858 OMIM:  601122 HGNC:  5294 Ensembl:  ENSG00000135914 UniProt:  P41595 Structure PDBPDBj LinkDB All DBs Position 2:complement(231108230..231125042) Genome browser AA seq 481 aa AA seqDB search MALSYRVSELQSTIPEHILQSTFVHVISSNWSGLQTESIPEEMKQIVEEQGNKLHWAALL ILMVIIPTIGGNTLVILAVSLEKKLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEAM WPLPLVLCPAWLFLDVLFSTASIMHLCAISVDRYIAIKKPIQANQYNSRATAFIKITVVW LISIGIAIPVPIKGIETDVDNPNNITCVLTKERFGDFMLFGSLAAFFTPLAIMIVTYFLT IHALQKKAYLVKNKPPQRLTWLTVSTVFQRDETPCSSPEKVAMLDGSRKDKALPNSGDET LMRRTSTIGKKSVQTISNEQRASKVLGIVFFLFLLMWCPFFITNITLVLCDSCNQTTLQM LLEIFVWIGYVSSGVNPLVYTLFNKTFRDAFGRYITCNYRATKSVKTLRKRSSKIYFRNP MAENSKFFKKHGIRNGINPAMYQSPMRLRSSTIQSSSIILLDTLLLTENEGDKTEEQVSY V NT seq 1446 nt NT seq  +upstreamnt  +downstreamnt atggctctctcttacagagtgtctgaacttcaaagcacaattcctgagcacattttgcag agcacctttgttcacgttatctcttctaactggtctggattacagacagaatcaatacca gaggaaatgaaacagattgttgaggaacagggaaataaactgcactgggcagctcttctg atactcatggtgataatacccacaattggtggaaatacccttgttattctggctgtttca ctggagaagaagctgcagtatgctactaattactttctaatgtccttggcggtggctgat ttgctggttggattgtttgtgatgccaattgccctcttgacaataatgtttgaggctatg tggcccctcccacttgttctatgtcctgcctggttatttcttgacgttctcttttcaacc gcatccatcatgcatctctgtgccatttcagtggatcgttacatagccatcaaaaagcca atccaggccaatcaatataactcacgggctacagcattcatcaagattacagtggtgtgg ttaatttcaataggcattgccattccagtccctattaaagggatagagactgatgtggac aacccaaacaatatcacttgtgtgctgacaaaggaacgttttggcgatttcatgctcttt ggctcactggctgccttcttcacacctcttgcaattatgattgtcacctactttctcact atccatgctttacagaagaaggcttacttagtcaaaaacaagccacctcaacgcctaaca tggttgactgtgtctacagttttccaaagggatgaaacaccttgctcgtcaccggaaaag gtggcaatgctggatggttctcgaaaggacaaggctctgcccaactcaggtgatgaaaca cttatgcgaagaacatccacaattgggaaaaagtcagtgcagaccatttccaacgaacag agagcctcaaaggtcctagggattgtgtttttcctctttttgcttatgtggtgtcccttc tttattacaaatataactttagttttatgtgattcctgtaaccaaactactctccaaatg ctcctggagatatttgtgtggataggctatgtttcctcaggagtgaatcctttggtctac accctcttcaataagacatttcgggatgcatttggccgatatatcacctgcaattaccgg gccacaaagtcagtaaaaactctcagaaaacgctccagtaagatctacttccggaatcca atggcagagaactctaagtttttcaagaaacatggaattcgaaatgggattaaccctgcc atgtaccagagtccaatgaggctccgaagttcaaccattcagtcttcatcaatcattcta ctagatacgcttctcctcactgaaaatgaaggtgacaaaactgaagagcaagttagttat gtatag

Homo sapiens (human): 3358 Help Entry 3358              CDS       T01001                                  Symbol HTR2C, 5-HT1C, 5-HT2C, 5-HTR2C, 5HTR2C, HTR1C Name (RefSeq) 5-hydroxytryptamine receptor 2C   KO K04157   5-hydroxytryptamine receptor 2 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04540   Gap junction hsa04726   Serotonergic synapse hsa04750   Inflammatory mediator regulation of TRP channels Network nt06528  Calcium signaling nt06544  Neuroactive ligand signaling   Element N01640   GPCR-PLCB-ITPR signaling pathway N01900   Serotonin-HTR2-GNAQ/11 signaling pathway Drug target Adatanserin hydrochloride:  D02767 Agomelatine:  D02578 Amesergide:  D02893 Asenapine (DG03100):  D02995<JP/US> Bexicaserin (DG03331):  D13035 D13036 Brolamfetamine:  D12707 Captodiame:  D07316 Chlorpromazine (DG00867):  D00270 D00789<JP/US> D03274 D04034<JP> D09819 Cinitapride (DG01520):  D07700 D07701 Clozapine:  D00283<JP/US> Cyamemazine (DG00872):  D07307 D07756 Cyproheptadine (DG01109):  D02234<JP/US> D07765 Dimetotiazine (DG00843):  D01902<JP> D07854 Fenfluramine (DG00103):  D04148<JP/US> D07945 Flibanserin:  D02577<US> Glemanserin:  D04320 Idalopirdine (DG01878):  D10710 Iloperidone:  D02666<US> Lorcaserin (DG03052):  D06613 D11566 Methysergide (DG00835):  D00681 D02357 Metrenperone:  D05015 Mianserin (DG00951):  D01358<JP> D08216 Milsaperidone:  D13099 Mirtazapine (DG02838):  D00563<JP/US> D11056 Nefazodone (DG00953):  D00819<US> D08257 Ocaperidone:  D02675 Olanzapine (DG00898):  D00454<JP/US> D06623<US> Opipramol (DG00930):  D01477 D08297 Pelanserin hydrochloride:  D05395 Periciazine:  D01485<JP> Pimavanserin:  D08969<US> Pizotifen (DG00842):  D05523 D08397 Ritanserin:  D05738 Sergolexole maleate:  D05829 Setoperone:  D02686 Tedatioxetine (DG01311):  D10170 D10171 Tiospirone hydrochloride:  D02688 Trazodone (DG00952):  D00820<JP/US> D08626 Tropanserin hydrochloride:  D06253 Vabicaserin hydrochloride:  D06660 Xylamidine tosylate:  D06343 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     3358 (HTR2C)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3358 (HTR2C)    04082 Neuroactive ligand signaling     3358 (HTR2C)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     3358 (HTR2C)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3358 (HTR2C)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     3358 (HTR2C)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3358 (HTR2C) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3358 (HTR2C) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7tm_4 7TM_GPCR_Srx Pox_P21 UPF0182 Motif Other DBs NCBI-GeneID:  3358 NCBI-ProteinID:  NP_000859 OMIM:  312861 HGNC:  5295 Ensembl:  ENSG00000147246 UniProt:  P28335 Structure PDBPDBj LinkDB All DBs Position X:114584086..114910061 Genome browser AA seq 458 aa AA seqDB search MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSI VIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWA ISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYV LRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTM QAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVC SGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTN EPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV NT seq 1377 nt NT seq  +upstreamnt  +downstreamnt atggtgaacctgaggaatgcggtgcattcattccttgtgcacctaattggcctattggtt tggcaatctgatatttctgtgagcccagtagcagctatagtaactgacattttcaatacc tccgatggtggacgcttcaaattcccagacggggtacaaaactggccagcactttcaatc gtcatcataataatcatgacaataggtggcaacatccttgtgatcatggcagtaagcatg gaaaagaaactgcacaatgccaccaattacttcttaatgtccctagccattgctgatatg ctagtgggactacttgtcatgcccctgtctctcctggcaatcctttatgattatgtctgg ccactacctagatatttgtgccccgtctggatttctttagatgttttattttcaacagcg tccatcatgcacctctgcgctatatcgctggatcggtatgtagcaatacgtaatcctatt gagcatagccgtttcaattcgcggactaaggccatcatgaagattgctattgtttgggca atttctataggtgtatcagttcctatccctgtgattggactgagggacgaagaaaaggtg ttcgtgaacaacacgacgtgcgtgctcaacgacccaaatttcgttcttattgggtccttc gtagctttcttcataccgctgacgattatggtgattacgtattgcctgaccatctacgtt ctgcgccgacaagctttgatgttactgcacggccacaccgaggaaccgcctggactaagt ctggatttcctgaagtgctgcaagaggaatacggccgaggaagagaactctgcaaaccct aaccaagaccagaacgcacgccgaagaaagaagaaggagagacgtcctaggggcaccatg caggctatcaacaatgaaagaaaagcttcgaaagtccttgggattgttttctttgtgttt ctgatcatgtggtgcccatttttcattaccaatattctgtctgttctttgtgagaagtcc tgtaaccaaaagctcatggaaaagcttctgaatgtgtttgtttggattggctatgtttgt tcaggaatcaatcctctggtgtatactctgttcaacaaaatttaccgaagggcattctcc aactatttgcgttgcaattataaggtagagaaaaagcctcctgtcaggcagattccaaga gttgccgccactgctttgtctgggagggagcttaatgttaacatttatcggcataccaat gaaccggtgatcgagaaagccagtgacaatgagcccggtatagagatgcaagttgagaat ttagagttaccagtaaatccctccagtgtggttagcgaaaggattagcagtgtgtga

Homo sapiens (human): 3360 Help Entry 3360              CDS       T01001                                  Symbol HTR4, 5-HT4, 5-HT4R Name (RefSeq) 5-hydroxytryptamine receptor 4   KO K04160   5-hydroxytryptamine receptor 4 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04024   cAMP signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04726   Serotonergic synapse Drug target Cinitapride (DG01520):  D07700 D07701 Cisapride (DG00056):  D00274 D02092 Fabesetron hydrochloride:  D01838 Felcisetrag:  D12157 Mosapride (DG01285):  D01994<JP> D08236 Naronapride (DG01335):  D09933 D09934 Piboserod hydrochloride:  D05471 Prucalopride (DG00080):  D09205 D10152<US> Relenopride (DG02948):  D11220 D11221 Renzapride:  D06396 Sulamserod hydrochloride:  D05941 Tegaserod (DG00081):  D02730 D06056 Velusetrag (DG01336):  D09693 D09694 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     3360 (HTR4)    04024 cAMP signaling pathway     3360 (HTR4)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3360 (HTR4)    04082 Neuroactive ligand signaling     3360 (HTR4)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3360 (HTR4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3360 (HTR4) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3360 (HTR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 DUF6249 zf-LITAF-like DUF7471 Motif Other DBs NCBI-GeneID:  3360 NCBI-ProteinID:  NP_000861 OMIM:  602164 HGNC:  5299 Ensembl:  ENSG00000164270 UniProt:  Q13639 A0A2D3FAF9 Structure PDBPDBj LinkDB All DBs Position 5:complement(148451032..148654527) Genome browser AA seq 388 aa AA seqDB search MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD AVECGGQWESQCHPPATSPLVAAQPSDT NT seq 1167 nt NT seq  +upstreamnt  +downstreamnt atggacaaacttgatgctaatgtgagttctgaggagggtttcgggtcagtggagaaggtg gtgctgctcacgtttctctcgacggttatcctgatggccatcttggggaacctgctggtg atggtggctgtgtgctgggacaggcagctcaggaaaataaaaacaaattatttcattgta tctcttgcttttgcggatctgctggtttcggtgctggtgatgccctttggtgccattgag ctggttcaagacatctggatttatggggaggtgttttgtcttgttcggacatctctggac gtcctgctcacaacggcatcgatttttcacctgtgctgcatttctctggataggtattac gccatctgctgccagcctttggtctataggaacaagatgacccctctgcgcatcgcatta atgctgggaggctgctgggtcatccccacgtttatttcttttctccctataatgcaaggc tggaataacattggcataattgatttgatagaaaagaggaagttcaaccagaactctaac tctacgtactgtgtcttcatggtcaacaagccctacgccatcacctgctctgtggtggcc ttctacatcccatttctcctcatggtgctggcctattaccgcatctatgtcacagctaag gagcatgcccatcagatccagatgttacaacgggcaggagcctcctccgagagcaggcct cagtcggcagaccagcatagcactcatcgcatgaggacagagaccaaagcagccaagacc ctgtgcatcatcatgggttgcttctgcctctgctgggcaccattctttgtcaccaatatt gtggatcctttcatagactacactgtccctgggcaggtgtggactgctttcctctggctc ggctatatcaattccgggttgaacccttttctctacgccttcttgaataagtcttttaga cgtgccttcctcatcatcctctgctgtgatgatgagcgctaccgaagaccttccattctg ggccagactgtcccttgttcaaccacaaccattaatggatccacacatgtactaagggat gcagtggagtgtggtggccagtgggagagtcagtgtcacccgccagcaacttctcctttg gtggctgctcagcccagtgacacttag

Homo sapiens (human): 3361 Help Entry 3361              CDS       T01001                                  Symbol HTR5A, 5-HT5A Name (RefSeq) 5-hydroxytryptamine receptor 5A   KO K04161   5-hydroxytryptamine receptor 5 Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04082   Neuroactive ligand signaling hsa04726   Serotonergic synapse Network nt06544  Neuroactive ligand signaling   Element N01901   Serotonin-HTR1/5-GNAI/O signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     3361 (HTR5A)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     3361 (HTR5A)    04082 Neuroactive ligand signaling     3361 (HTR5A)  09150 Organismal Systems   09156 Nervous system    04726 Serotonergic synapse     3361 (HTR5A)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     3361 (HTR5A) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Biogenic amine    Serotonin     3361 (HTR5A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srx DUF8845 TgpA_N Motif Other DBs NCBI-GeneID:  3361 NCBI-ProteinID:  NP_076917 OMIM:  601305 HGNC:  5300 Ensembl:  ENSG00000157219 UniProt:  P47898 A4D2N2 Structure PDBPDBj LinkDB All DBs Position 7:155070324..155087392 Genome browser AA seq 357 aa AA seqDB search MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLL VLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIAC DVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFG WGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVS PISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIP FFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH NT seq 1074 nt NT seq  +upstreamnt  +downstreamnt atggatttacctgtgaacctaacctccttttccctctccaccccctcccctttggagacc aaccacagcctcggcaaagacgacctgcgccccagctcgcccctgctctcggtcttcgga gtgcttattctcaccttgctgggctttctggtggcggcgacgttcgcctggaacctgctg gtgctggcgaccatcctccgtgtacgcaccttccaccgcgtgccccacaacctggtggca tccatggccgtctcggatgtcctggtggccgcgctggtcatgccgctgagcctggtgcac gagctgtccgggcgccgctggcagctaggtcggaggctgtgccagctttggatcgcgtgc gacgtgctttgctgcacggccagcatctggaacgtgacggccatagccctggaccgctac tggtccatcacgcgccacatggaatacacgctccgcacccgcaagtgcgtctccaacgtc atgatcgcgctcacctgggcactctccgctgtcatctctctggccccgctgctttttggc tggggagagacgtactctgagggcagcgaggagtgccaggtaagccgcgagccttcctac gccgtgttctccaccgtaggcgccttctacctgccgctctgtgtggtgctcttcgtgtac tggaagatctacaaggctgccaagttccgcgtgggctccaggaagaccaatagcgtctca cccatatccgaagctgtggaggtgaaggactctgccaaacagccccagatggtgttcacg gtccgccacgccaccgtcaccttccagccagaaggggacacgtggcgggagcagaaggag cagcgggccgccctcatggtgggcatcctcattggcgtgttcgtgctctgctggatcccc ttctttctcaccgagctcatcagtcccctctgctcctgtgacatccccgccatctggaaa agcatcttcctgtggcttggctactccaactccttctttaaccccctgatctatacggct ttcaacaagaactacaacagcgccttcaagaacttcttttctaggcaacactga

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