KEGG   Homo sapiens (human): 3397
Entry
3397              CDS       T01001                                 
Symbol
ID1, ID, bHLHb24
Name
(RefSeq) inhibitor of DNA binding 1
  KO
K04680  DNA-binding protein inhibitor ID1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04015  Rap1 signaling pathway
hsa04350  TGF-beta signaling pathway
hsa04390  Hippo signaling pathway
hsa04550  Signaling pathways regulating pluripotency of stem cells
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    3397 (ID1)
   04350 TGF-beta signaling pathway
    3397 (ID1)
   04390 Hippo signaling pathway
    3397 (ID1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    3397 (ID1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    3397 (ID1)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Basic helix-loop-helix (bHLH)
   HLH domain only
    3397 (ID1)
SSDB
Motif
Pfam: HLH Dsl1_N
Other DBs
NCBI-GeneID: 3397
NCBI-ProteinID: NP_002156
OMIM: 600349
HGNC: 5360
Ensembl: ENSG00000125968
UniProt: P41134
LinkDB
Position
20:31605289..31606510
AA seq 155 aa
MKVASGSTATAAAGPSCALKAGKTASGAGEVVRCLSEQSVAISRCAGGAGARLPALLDEQ
QVNVLLYDMNGCYSRLKELVPTLPQNRKVSKVEILQHVIDYIRDLQLELNSESEVGTPGG
RGLPVRAPLSTLNGEISALTAEAACVPADDRILCR
NT seq 468 nt   +upstreamnt  +downstreamnt
atgaaagtcgccagtggcagcaccgccaccgccgccgcgggccccagctgcgcgctgaag
gccggcaagacagcgagcggtgcgggcgaggtggtgcgctgtctgtctgagcagagcgtg
gccatctcgcgctgcgccgggggcgccggggcgcgcctgcctgccctgctggacgagcag
caggtaaacgtgctgctctacgacatgaacggctgttactcacgcctcaaggagctggtg
cccaccctgccccagaaccgcaaggtgagcaaggtggagattctccagcacgtcatcgac
tacatcagggaccttcagttggagctgaactcggaatccgaagttggaacccccgggggc
cgagggctgccggtccgggctccgctcagcaccctcaacggcgagatcagcgccctgacg
gccgaggcggcatgcgttcctgcggacgatcgcatcttgtgtcgctga

KEGG   Homo sapiens (human): 3398
Entry
3398              CDS       T01001                                 
Symbol
ID2, GIG8, ID2A, ID2H, bHLHb26
Name
(RefSeq) inhibitor of DNA binding 2
  KO
K17693  DNA-binding protein inhibitor ID2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04350  TGF-beta signaling pathway
hsa04390  Hippo signaling pathway
hsa04550  Signaling pathways regulating pluripotency of stem cells
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription (cancer)
  Element
N00133  EWSR1-FLI1 fusion to transcriptional activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    3398 (ID2)
   04390 Hippo signaling pathway
    3398 (ID2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    3398 (ID2)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    3398 (ID2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    3398 (ID2)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Basic helix-loop-helix (bHLH)
   HLH domain only
    3398 (ID2)
SSDB
Motif
Pfam: HLH DUF6847
Other DBs
NCBI-GeneID: 3398
NCBI-ProteinID: NP_002157
OMIM: 600386
HGNC: 5361
Ensembl: ENSG00000115738
UniProt: Q02363 Q53T66
Structure
LinkDB
Position
2:8682056..8684461
AA seq 134 aa
MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVS
KMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEF
PSELMSNDSKALCG
NT seq 405 nt   +upstreamnt  +downstreamnt
atgaaagccttcagtcccgtgaggtccgttaggaaaaacagcctgtcggaccacagcctg
ggcatctcccggagcaaaacccctgtggacgacccgatgagcctgctatacaacatgaac
gactgctactccaagctcaaggagctggtgcccagcatcccccagaacaagaaggtgagc
aagatggaaatcctgcagcacgtcatcgactacatcttggacctgcagatcgccctggac
tcgcatcccactattgtcagcctgcatcaccagagacccgggcagaaccaggcgtccagg
acgccgctgaccaccctcaacacggatatcagcatcctgtccttgcaggcttctgaattc
ccttctgagttaatgtcaaatgacagcaaagcactgtgtggctga

KEGG   Homo sapiens (human): 3399
Entry
3399              CDS       T01001                                 
Symbol
ID3, HEIR-1, bHLHb25
Name
(RefSeq) inhibitor of DNA binding 3
  KO
K17694  DNA-binding protein inhibitor ID3
Organism
hsa  Homo sapiens (human)
Pathway
hsa04350  TGF-beta signaling pathway
hsa04550  Signaling pathways regulating pluripotency of stem cells
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    3399 (ID3)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    3399 (ID3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    3399 (ID3)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Basic helix-loop-helix (bHLH)
   HLH domain only
    3399 (ID3)
SSDB
Motif
Pfam: HLH HP1454-like_middle_dom
Other DBs
NCBI-GeneID: 3399
NCBI-ProteinID: NP_002158
OMIM: 600277
HGNC: 5362
Ensembl: ENSG00000117318
UniProt: Q02535
Structure
LinkDB
Position
1:complement(23557926..23559501)
AA seq 119 aa
MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSRLRELVPGVPR
GTQLSQVEILQRVIDYILDLQVVLAEPAPGPPDGPHLPIQTAELTPELVISNDKRSFCH
NT seq 360 nt   +upstreamnt  +downstreamnt
atgaaggcgctgagcccggtgcgcggctgctacgaggcggtgtgctgcctgtcggaacgc
agtctggccatcgcccggggccgagggaagggcccggcagctgaggagccgctgagcttg
ctggacgacatgaaccactgctactcccgcctgcgggaactggtacccggagtcccgaga
ggcactcagcttagccaggtggaaatcctacagcgcgtcatcgactacattctcgacctg
caggtagtcctggccgagccagcccctggaccccctgatggcccccaccttcccatccag
acagccgagctcactccggaacttgtcatctccaacgacaaaaggagcttttgccactga

KEGG   Homo sapiens (human): 3400
Entry
3400              CDS       T01001                                 
Symbol
ID4, IDB4, bHLHb27
Name
(RefSeq) inhibitor of DNA binding 4
  KO
K17695  DNA-binding protein inhibitor ID4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04350  TGF-beta signaling pathway
hsa04550  Signaling pathways regulating pluripotency of stem cells
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    3400 (ID4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    3400 (ID4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    3400 (ID4)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Basic helix-loop-helix (bHLH)
   HLH domain only
    3400 (ID4)
SSDB
Motif
Pfam: HLH
Other DBs
NCBI-GeneID: 3400
NCBI-ProteinID: NP_001537
OMIM: 600581
HGNC: 5363
Ensembl: ENSG00000172201
UniProt: P47928
LinkDB
Position
6:19837370..19842197
AA seq 161 aa
MKAVSPVRPSGRKAPSGCGGGELALRCLAEHGHSLGGSAAAAAAAAAARCKAAEAAADEP
ALCLQCDMNDCYSRLRRLVPTIPPNKKVSKVEILQHVIDYILDLQLALETHPALLRQPPP
PAPPHHPAGTCPAAPPRTPLTALNTDPAGAVNKQGDSILCR
NT seq 486 nt   +upstreamnt  +downstreamnt
atgaaggcggtgagcccggtgcgcccctcgggccgcaaggcgccgtcgggctgcggcggc
ggggagctggcgctgcgctgcctggccgagcacggccacagcctgggtggctccgcagcc
gcggcggcggcggcggcggcagcgcgctgtaaggcggccgaggcggcggccgacgagccg
gcgctgtgcctgcagtgcgatatgaacgactgctatagccgcctgcggaggctggtgccc
accatcccgcccaacaagaaagtcagcaaagtggagatcctgcagcacgttatcgactac
atcctggacctgcagctggcgctggagacgcacccggccctgctgaggcagccaccaccg
cccgcgccgccacaccacccggccgggacctgtccagccgcgccgccgcggaccccgctc
actgcgctcaacaccgacccggccggcgcggtgaacaagcagggcgacagcattctgtgc
cgctga

DBGET integrated database retrieval system