Homo sapiens (human): 35
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Entry
35 CDS
T01001
Symbol
ACADS, ACAD3, SCAD
Name
(RefSeq) acyl-CoA dehydrogenase short chain
KO
K00248
butyryl-CoA dehydrogenase [EC:
1.3.8.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00071
Fatty acid degradation
hsa00280
Valine, leucine and isoleucine degradation
hsa00410
beta-Alanine metabolism
hsa00640
Propanoate metabolism
hsa00650
Butanoate metabolism
hsa01100
Metabolic pathways
hsa01200
Carbon metabolism
hsa01212
Fatty acid metabolism
Network
nt06020
beta-Oxidation in mitochondria
nt06024
Valine, leucine and isoleucine degradation
Element
N00804
beta-Oxidation
N00852
Valine degradation
N00856
Isoleucine degradation
Disease
H00525
Disorders of mitochondrial fatty-acid oxidation
H01980
SCAD deficiency
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
35 (ACADS)
00650 Butanoate metabolism
35 (ACADS)
09103 Lipid metabolism
00071 Fatty acid degradation
35 (ACADS)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
35 (ACADS)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
35 (ACADS)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.8 With a flavin as acceptor
1.3.8.1 short-chain acyl-CoA dehydrogenase
35 (ACADS)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Acyl-CoA_dh_1
Acyl-CoA_dh_N
Acyl-CoA_dh_M
Acyl-CoA_dh_2
ACOX_C_alpha1
HpaB_N
Motif
Other DBs
NCBI-GeneID:
35
NCBI-ProteinID:
NP_000008
OMIM:
606885
HGNC:
90
Ensembl:
ENSG00000122971
Pharos:
P16219
(Tbio)
UniProt:
P16219
E5KSD5
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:120725826..120740008
Genome browser
AA seq
412 aa
AA seq
DB search
MAAALLARASGPARRALCPRAWRQLHTIYQSVELPETHQMLLQTCRDFAEKELFPIAAQV
DKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNN
SLYLGPILKFGSKEQKQAWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLN
GTKAWITNAWEASAAVVFASTDRALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTAN
LIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAF
GAPLTKLQVIQFKLADMALALESARLLTWRAAMLKDNKKPFIKEAAMAKLAASEAATAIS
HQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQRLVIAGHLLRSYRS
NT seq
1239 nt
NT seq
+upstream
nt +downstream
nt
atggccgccgcgctgctcgcccgggcctcgggccctgcccgcagagctctctgtcctagg
gcctggcggcagttacacaccatctaccagtctgtggaactgcccgagacacaccagatg
ttgctccagacatgccgggactttgccgagaaggagttgtttcccattgcagcccaggtg
gataaggaacatctcttcccagcggctcaggtgaagaagatgggcgggcttgggcttctg
gccatggacgtgcccgaggagcttggcggtgctggcctcgattacctggcctacgccatc
gccatggaggagatcagccgtggctgcgcctccaccggagtcatcatgagtgtcaacaac
tctctctacctggggcccatcttgaagtttggctccaaggagcagaagcaggcgtgggtc
acgcctttcaccagtggtgacaaaattggctgctttgccctcagcgaaccagggaacggc
agtgatgcaggagctgcgtccaccaccgcccgggccgagggcgactcatgggttctgaat
ggaaccaaagcctggatcaccaatgcctgggaggcttcggctgccgtggtctttgccagc
acggacagagccctgcaaaacaagggcatcagtgccttcctggtccccatgccaacgcct
gggctcacgttggggaagaaagaagacaagctgggcatccggggctcatccacggccaac
ctcatctttgaggactgtcgcatccccaaggacagcatcctgggggagccagggatgggc
ttcaagatagccatgcaaaccctggacatgggccgcatcggcatcgcctcccaggccctg
ggcattgcccagaccgccctcgattgtgctgtgaactacgctgagaatcgcatggccttc
ggggcgcccctcaccaagctccaggtcatccagttcaagttggcagacatggccctggcc
ctggagagtgcccggctgctgacctggcgcgctgccatgctgaaggataacaagaagcct
ttcatcaaggaggcagccatggccaagctggccgcctcggaggccgcgaccgccatcagc
caccaggccatccagatcctgggcggcatgggctacgtgacagagatgccggcagagcgg
cactaccgcgacgcccgcatcactgagatctacgagggcaccagcgaaatccagcggctg
gtgatcgccgggcatctgctcaggagctaccggagctga
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