Homo sapiens (human): 36
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Entry
36 CDS
T01001
Symbol
ACADSB, 2-MEBCAD, ACAD7, SBCAD
Name
(RefSeq) acyl-CoA dehydrogenase short/branched chain
KO
K09478
short-chain 2-methylacyl-CoA dehydrogenase [EC:
1.3.8.5
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00071
Fatty acid degradation
hsa00280
Valine, leucine and isoleucine degradation
hsa01100
Metabolic pathways
hsa01212
Fatty acid metabolism
Network
nt06020
beta-Oxidation in mitochondria
nt06024
Valine, leucine and isoleucine degradation
Element
N00804
beta-Oxidation
N00856
Isoleucine degradation
Disease
H00375
SBCAD deficiency
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00071 Fatty acid degradation
36 (ACADSB)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
36 (ACADSB)
Enzymes [BR:
hsa01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.8 With a flavin as acceptor
1.3.8.5 short-chain 2-methylacyl-CoA dehydrogenase
36 (ACADSB)
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GFIT
Motif
Pfam:
Acyl-CoA_dh_1
Acyl-CoA_dh_N
Acyl-CoA_dh_2
Acyl-CoA_dh_M
ACOX_C_alpha1
Motif
Other DBs
NCBI-GeneID:
36
NCBI-ProteinID:
NP_001600
OMIM:
600301
HGNC:
91
Ensembl:
ENSG00000196177
Pharos:
P45954
(Tbio)
UniProt:
P45954
A0A0S2Z3P9
Structure
PDB
PDBj
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Position
10:123009006..123058290
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AA seq
432 aa
AA seq
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MEGLAVRLLRGSRLLRRNFLTCLSSWKIPPHVSKSSQSEALLNITNNGIHFAPLQTFTDE
EMMIKSSVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGLMGIEVDPEYGGTGASFLS
TVLVIEELAKVDASVAVFCEIQNTLINTLIRKHGTEEQKATYLPQLTTEKVGSFCLSEAG
AGSDSFALKTRADKEGDYYVLNGSKMWISSAEHAGLFLVMANVDPTIGYKGITSFLVDRD
TPGLHIGKPENKLGLRASSTCPLTFENVKVPEANILGQIGHGYKYAIGSLNEGRIGIAAQ
MLGLAQGCFDYTIPYIKERIQFGKRLFDFQGLQHQVAHVATQLEAARLLTYNAARLLEAG
KPFIKEASMAKYYASEIAGQTTSKCIEWMGGVGYTKDYPVEKYFRDAKIGTIYEGASNIQ
LNTIAKHIDAEY
NT seq
1299 nt
NT seq
+upstream
nt +downstream
nt
atggagggcctggcagtgcggttgctgcgcggcagcaggctgctaagaagaaatttcctg
acttgtttgtcttcttggaagattcctcctcatgtctcaaaatcttcccagtcagaagct
ctactcaatataacaaataatggaatacactttgctcccctgcaaacatttacagatgag
gaaatgatgataaagagttcagttaaaaaatttgctcaggaacaaattgcacctttggtt
tcaaccatggatgaaaattcgaaaatggagaaatcagtaatacaaggattatttcaacaa
gggttgatgggtattgaagttgacccagaatatggaggcacaggagcttcatttttatcc
actgtgctcgtgatagaggaattagccaaagttgatgcatctgtggctgtcttttgtgag
atccagaacacattaattaacacactgattagaaaacatggaacagaagaacaaaaggcc
acctatttgcctcagctcactacagaaaaagtaggaagtttctgcctttcagaggctgga
gcaggtagtgactcatttgctttgaagaccagagctgataaagagggagattattatgtc
ctcaatggatcaaagatgtggatcagcagtgctgagcacgcagggctctttctggtgatg
gcaaatgtagaccctaccattggatataagggaattacctccttcttagtagatcgtgat
actccgggccttcatatagggaaacctgaaaacaaattggggctcagagcttcttccacc
tgcccgttaacattcgaaaatgtcaaggttccagaagccaatatcttgggacaaattgga
catggctataagtatgccatagggagtctcaatgaaggtagaataggaattgctgcacag
atgctgggactggcgcaaggatgttttgactacactattccatatattaaagaaaggata
caatttggcaaaagactatttgattttcagggcctccaacaccaagtggctcacgtggcc
acccagctggaagctgcaagattactaacatacaatgctgctaggcttttagaagctgga
aagccattcataaaagaagcgtcaatggccaaatactatgcatcagagattgcaggacaa
acaacgagtaaatgtatcgagtggatggggggagtaggctacaccaaagattaccctgtg
gagaaatacttccgagatgcaaagattggtacgatatatgaaggagcttccaacatccag
ttgaacaccattgcaaagcatatcgatgcagaatactga
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