KEGG T01001: 367

Homo sapiens (human): 367

Entry

367               CDS       T01001

Symbol

AR, AIS, AR8, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM

Name

(RefSeq) androgen receptor

K08557

androgen receptor

Organism

hsa Homo sapiens (human)

Pathway

hsa04114

Oocyte meiosis

hsa05200

Pathways in cancer

hsa05207

Chemical carcinogenesis - receptor activation

hsa05215

Prostate cancer

Network

nt06227 Nuclear receptor signaling (cancer)
nt06272 Prostate cancer

Element

N00083

Androgen receptor signaling pathway

N00084

Amplified AR to androgen receptor signaling pathway

N00085

Mutation-activated AR to androgen receptor signaling pathway

Disease

H00024

Prostate cancer

H00062

Spinal and bulbar muscular atrophy (SBMA)

H00455

Spinal muscular atrophy

H02175

Hypospadias

H02177

Androgen insensitivity syndrome

Drug target

Androstanolone:

D07456

Apalutamide:

D11040<JP/US>

Bavdegalutamide:

D12316

Benorterone:

D03079

Bicalutamide:

D00961<JP/US>

Bolasterone:

D03144

Boldenone (DG01275):

D03145 D07536

Calusterone:

D03338

Chlormadinone (DG00469):

D01299<JP> D07670

Cioteronel:

D03515

Clascoterone:

D11451<US>

Clometherone:

D03551

Cyproterone (DG00475):

D01368 D07766

Danazol:

D00289<JP/US>

Darolutamide:

D11045<JP/US>

Delmadinone (DG02935):

D03675 D07783

Deutenzalutamide:

D12303

Dromostanolone propionate:

D01534

Enobosarm:

D10221

Enzalutamide:

D10218<JP/US>

Fluoxymesterone:

D00327

Flutamide:

D00586<JP/US>

Gridegalutamide:

Masofaniten:

Mestanolone:

Mesterolone:

Metandienone:

Metenolone (DG00140):

D01301 D01375<JP> D08193

Methandriol (DG01276):

D08196 D08197

Methyltestosterone:

D00408<US>

Mibolerone:

D05025

Nandrolone (DG00142):

D00955 D00956 D01476 D01737 D05116 D08250 D08251

Nilutamide:

D00965<US>

Nisterime acetate:

Norethandrolone:

Osaterone acetate:

Oxabolone cipionate:

Oxandrolone:

D00462<US>

Oxendolone:

D01329

Oxymetholone:

D00490

Prasterone (DG00141):

D01616 D08409<US>

Quinbolone:

Ralaniten (DG02945):

Silandrone:

Stanozolol:

Testosterone (DG00460):

D00075<US> D00957<US> D00958<JP/US> D00959 D06085 D06086 D06087<US> D08573 D08574

Topterone:

D06191

Trenbolone (DG01631):

D06211 D08627

Zanoterone:

D06357

Brite

KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    367 (AR)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    367 (AR)
   05207 Chemical carcinogenesis - receptor activation
    367 (AR)
  09162 Cancer: specific types
   05215 Prostate cancer
    367 (AR)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    367 (AR)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:hsa03310]
    367 (AR)
Transcription factors [BR:hsa03000]
Eukaryotic type
  Zinc finger
   Cys4 estrogen receptor-like
    367 (AR)
Nuclear receptors [BR:hsa03310]
3. Estrogen like
  3C. 3-Ketosteroid receptor
   367 (AR)

SSDB

Motif

Pfam:

Androgen_recep Hormone_recep zf-C4 U3_snoRNA_assoc

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Pharos:

P10275(Tclin)

UniProt:

P10275 Q9NUA2

Structure

LinkDB

Position

X:67544021..67730619

AA seq 920 aa
MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQ
QQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQ
SALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSAD
LKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELC
KAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAG
KSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQ
SRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAA
GPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAP
YGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRL
ETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRN
DCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKL
TVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWA
KALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSR
MYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELD
RIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEII
SVQVPKILSGKVKPIYFHTQ

NT seq 2763 nt +upstreamnt +downstreamnt
atggaagtgcagttagggctgggaagggtctaccctcggccgccgtccaagacctaccga
ggagctttccagaatctgttccagagcgtgcgcgaagtgatccagaacccgggccccagg
cacccagaggccgcgagcgcagcacctcccggcgccagtttgctgctgctgcagcagcag
cagcagcagcagcagcagcagcagcagcagcagcagcagcagcagcagcagcagcagcaa
gagactagccccaggcagcagcagcagcagcagggtgaggatggttctccccaagcccat
cgtagaggccccacaggctacctggtcctggatgaggaacagcaaccttcacagccgcag
tcggccctggagtgccaccccgagagaggttgcgtcccagagcctggagccgccgtggcc
gccagcaaggggctgccgcagcagctgccagcacctccggacgaggatgactcagctgcc
ccatccacgttgtccctgctgggccccactttccccggcttaagcagctgctccgctgac
cttaaagacatcctgagcgaggccagcaccatgcaactccttcagcaacagcagcaggaa
gcagtatccgaaggcagcagcagcgggagagcgagggaggcctcgggggctcccacttcc
tccaaggacaattacttagggggcacttcgaccatttctgacaacgccaaggagttgtgt
aaggcagtgtcggtgtccatgggcctgggtgtggaggcgttggagcatctgagtccaggg
gaacagcttcggggggattgcatgtacgccccacttttgggagttccacccgctgtgcgt
cccactccttgtgccccattggccgaatgcaaaggttctctgctagacgacagcgcaggc
aagagcactgaagatactgctgagtattcccctttcaagggaggttacaccaaagggcta
gaaggcgagagcctaggctgctctggcagcgctgcagcagggagctccgggacacttgaa
ctgccgtctaccctgtctctctacaagtccggagcactggacgaggcagctgcgtaccag
agtcgcgactactacaactttccactggctctggccggaccgccgccccctccgccgcct
ccccatccccacgctcgcatcaagctggagaacccgctggactacggcagcgcctgggcg
gctgcggcggcgcagtgccgctatggggacctggcgagcctgcatggcgcgggtgcagcg
ggacccggttctgggtcaccctcagccgccgcttcctcatcctggcacactctcttcaca
gccgaagaaggccagttgtatggaccgtgtggtggtggtgggggtggtggcggcggcggc
ggcggcggcggcggcggcggcggcggcggcggcggcggcgaggcgggagctgtagccccc
tacggctacactcggccccctcaggggctggcgggccaggaaagcgacttcaccgcacct
gatgtgtggtaccctggcggcatggtgagcagagtgccctatcccagtcccacttgtgtc
aaaagcgaaatgggcccctggatggatagctactccggaccttacggggacatgcgtttg
gagactgccagggaccatgttttgcccattgactattactttccaccccagaagacctgc
ctgatctgtggagatgaagcttctgggtgtcactatggagctctcacatgtggaagctgc
aaggtcttcttcaaaagagccgctgaagggaaacagaagtacctgtgcgccagcagaaat
gattgcactattgataaattccgaaggaaaaattgtccatcttgtcgtcttcggaaatgt
tatgaagcagggatgactctgggagcccggaagctgaagaaacttggtaatctgaaacta
caggaggaaggagaggcttccagcaccaccagccccactgaggagacaacccagaagctg
acagtgtcacacattgaaggctatgaatgtcagcccatctttctgaatgtcctggaagcc
attgagccaggtgtagtgtgtgctggacacgacaacaaccagcccgactcctttgcagcc
ttgctctctagcctcaatgaactgggagagagacagcttgtacacgtggtcaagtgggcc
aaggccttgcctggcttccgcaacttacacgtggacgaccagatggctgtcattcagtac
tcctggatggggctcatggtgtttgccatgggctggcgatccttcaccaatgtcaactcc
aggatgctctacttcgcccctgatctggttttcaatgagtaccgcatgcacaagtcccgg
atgtacagccagtgtgtccgaatgaggcacctctctcaagagtttggatggctccaaatc
accccccaggaattcctgtgcatgaaagcactgctactcttcagcattattccagtggat
gggctgaaaaatcaaaaattctttgatgaacttcgaatgaactacatcaaggaactcgat
cgtatcattgcatgcaaaagaaaaaatcccacatcctgctcaagacgcttctaccagctc
accaagctcctggactccgtgcagcctattgcgagagagctgcatcagttcacttttgac
ctgctaatcaagtcacacatggtgagcgtggactttccggaaatgatggcagagatcatc
tctgtgcaagtgcccaagatcctttctgggaaagtcaagcccatctatttccacacccag
tga

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