Homo sapiens (human): 3816 Help Entry 3816              CDS       T01001                                  Symbol KLK1, KLKR, Klk6, hK1 Name (RefSeq) kallikrein 1   KO K01325   tissue kallikrein [EC:3.4.21.35] Organism hsa  Homo sapiens (human) Pathway hsa04614   Renin-angiotensin system hsa04961   Endocrine and other factor-regulated calcium reabsorption Drug target Gabexate (DG01400):  D01672<JP> D08004 Brite KEGG Orthology (KO) [BR:hsa00001]  09150 Organismal Systems   09152 Endocrine system    04614 Renin-angiotensin system     3816 (KLK1)   09155 Excretory system    04961 Endocrine and other factor-regulated calcium reabsorption     3816 (KLK1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hsa01002]     3816 (KLK1)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     3816 (KLK1) Enzymes [BR:hsa01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.21  Serine endopeptidases     3.4.21.35  tissue kallikrein      3816 (KLK1) Peptidases and inhibitors [BR:hsa01002]  Serine peptidases   Family S1: chymotrypsin family    3816 (KLK1) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    3816 (KLK1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Trypsin Trypsin_2 DUF1986 Motif Other DBs NCBI-GeneID:  3816 NCBI-ProteinID:  NP_002248 OMIM:  147910 HGNC:  6357 Ensembl:  ENSG00000167748 Pharos:  P06870(Tchem) UniProt:  P06870 A0A1R3UCD2 Structure PDB LinkDB All DBs Position 19:complement(50819146..50823787) Genome browser AA seq 262 aa AA seqDB search MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK PSVAVRVLSYVKWIEDTIAENS NT seq 789 nt NT seq  +upstreamnt  +downstreamnt atgtggttcctggttctgtgcctcgccctgtccctgggggggactggtgctgcgcccccg attcagtcccggattgtgggaggctgggagtgtgagcagcattcccagccctggcaggcg gctctgtaccatttcagcactttccagtgtgggggcatcctggtgcaccgccagtgggtg ctcacagctgctcattgcatcagcgacaattaccagctctggctgggtcgccacaacttg tttgacgacgaaaacacagcccagtttgttcatgtcagtgagagcttcccacaccctggc ttcaacatgagcctcctggagaaccacacccgccaagcagacgaggactacagccacgac ctcatgctgctccgcctgacagagcctgctgataccatcacagatgctgtgaaggtcgtg gagttgcccaccgaggaacccgaagtggggagcacctgtttggcttccggctggggcagc atcgaaccagagaatttctcatttccagatgatctccagtgtgtggacctcaaaatcctg cctaatgatgagtgcaaaaaagcccacgtccagaaggtgacagacttcatgctgtgtgtc ggacacctggaaggtggcaaagacacctgtgtgggtgattcagggggcccgctgatgtgt gatggtgtgctccaaggtgtcacatcatggggctacgtcccttgtggcacccccaataag ccttctgtcgccgtcagagtgctgtcttatgtgaagtggatcgaggacaccatagcggag aactcctga

Homo sapiens (human): 3817 Help Entry 3817              CDS       T01001                                  Symbol KLK2, KLK2A2, hGK-1, hK2 Name (RefSeq) kallikrein related peptidase 2   KO K01325   tissue kallikrein [EC:3.4.21.35] Organism hsa  Homo sapiens (human) Pathway hsa04614   Renin-angiotensin system hsa04961   Endocrine and other factor-regulated calcium reabsorption Drug target Gabexate (DG01400):  D01672<JP> D08004 Brite KEGG Orthology (KO) [BR:hsa00001]  09150 Organismal Systems   09152 Endocrine system    04614 Renin-angiotensin system     3817 (KLK2)   09155 Excretory system    04961 Endocrine and other factor-regulated calcium reabsorption     3817 (KLK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:hsa01002]     3817 (KLK2)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     3817 (KLK2) Enzymes [BR:hsa01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.21  Serine endopeptidases     3.4.21.35  tissue kallikrein      3817 (KLK2) Peptidases and inhibitors [BR:hsa01002]  Serine peptidases   Family S1: chymotrypsin family    3817 (KLK2) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    3817 (KLK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Trypsin Trypsin_2 DUF1986 Motif Other DBs NCBI-GeneID:  3817 NCBI-ProteinID:  NP_005542 OMIM:  147960 HGNC:  6363 Ensembl:  ENSG00000167751 Pharos:  P20151(Tbio) UniProt:  P20151 A0A024R4J4 B4DU77 Structure PDB LinkDB All DBs Position 19:50873439..50880567 Genome browser AA seq 261 aa AA seqDB search MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP AVYTKVVHYRKWIKDTIAANP NT seq 786 nt NT seq  +upstreamnt  +downstreamnt atgtgggacctggttctctccatcgccttgtctgtggggtgcactggtgccgtgcccctc atccagtctcggattgtgggaggctgggagtgtgagaagcattcccaaccctggcaggtg gctgtgtacagtcatggatgggcacactgtgggggtgtcctggtgcacccccagtgggtg ctcacagctgcccattgcctaaagaagaatagccaggtctggctgggtcggcacaacctg tttgagcctgaagacacaggccagagggtccctgtcagccacagcttcccacacccgctc tacaatatgagccttctgaagcatcaaagccttagaccagatgaagactccagccatgac ctcatgctgctccgcctgtcagagcctgccaagatcacagatgttgtgaaggtcctgggc ctgcccacccaggagccagcactggggaccacctgctacgcctcaggctggggcagcatc gaaccagaggagttcttgcgccccaggagtcttcagtgtgtgagcctccatctcctgtcc aatgacatgtgtgctagagcttactctgagaaggtgacagagttcatgttgtgtgctggg ctctggacaggtggtaaagacacttgtgggggtgattctgggggtccacttgtctgtaat ggtgtgcttcaaggtatcacatcatggggccctgagccatgtgccctgcctgaaaagcct gctgtgtacaccaaggtggtgcattaccggaagtggatcaaggacaccatcgcagccaac ccctga

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