Homo sapiens (human): 4645
Help
Entry
4645 CDS
T01001
Symbol
MYO5B, DIAR2, MVID1, PFIC10
Name
(RefSeq) myosin VB
KO
K10357
myosin V
Organism
hsa
Homo sapiens (human)
Pathway
hsa04814
Motor proteins
hsa05130
Pathogenic Escherichia coli infection
Network
nt06541
Cytoskeleton in neurons
Element
N01850
MYO5B-mediated vesicle transport
Disease
H00624
Progressive familial intrahepatic cholestasis
H01174
Congenital diarrhea
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09142 Cell motility
04814 Motor proteins
4645 (MYO5B)
09160 Human Diseases
09171 Infectious disease: bacterial
05130 Pathogenic Escherichia coli infection
4645 (MYO5B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
4645 (MYO5B)
04131 Membrane trafficking [BR:
hsa04131
]
4645 (MYO5B)
03029 Mitochondrial biogenesis [BR:
hsa03029
]
4645 (MYO5B)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
4645 (MYO5B)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
Factors involved in mRNA localization
Cargo complex
4645 (MYO5B)
mRNA cycle factors
P-body specific factors
4645 (MYO5B)
Membrane trafficking [BR:
hsa04131
]
Others
Actin-binding proteins
Myosins
4645 (MYO5B)
Mitochondrial biogenesis [BR:
hsa03029
]
Mitochondrial quality control factors
Mitochondrial dynamics
Retention of mitochondria
4645 (MYO5B)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Myosins
4645 (MYO5B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Myosin_head
Myo5a
DIL
IQ
nSTAND3
Myosin_N
Tmemb_161AB
AAA_16
AAA_22
NPHP3_N
Motif
Other DBs
NCBI-GeneID:
4645
NCBI-ProteinID:
NP_001073936
OMIM:
606540
HGNC:
7603
Ensembl:
ENSG00000167306
UniProt:
Q9ULV0
Q7Z7A5
Structure
PDB
PDBj
LinkDB
All DBs
Position
18:complement(49822789..50195147)
Genome browser
AA seq
1848 aa
AA seq
DB search
MSVGELYSQCTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLP
FLRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYG
QDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYF
ATVGGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMR
TYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVD
DAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSN
FCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHI
NKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMK
EQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQK
PRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPVP
ATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKP
NDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELANTD
KKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQ
KVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAV
VIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKAR
RELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVE
RLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADL
EQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQR
YDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAA
MDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSL
KRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEE
VLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDW
GYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFC
QTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAA
QALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDLKPQMLSGTVPCL
PAYILYMCIRHADYTNDDLKVHSLLTSTINGIKKVLKKHNDDFEMTSFWLSNTCRLLHCL
KQYSGDEGFMTQNTAKQNEHCLKNFDLTEYRQVLSDLSIQIYQQLIKIAEGVLQPMIVSA
MLENESIQGLSGVKPTGYRKRSSSMADGDNSYCLEAIIRQMNAFHTVMCDQGLDPEIILQ
VFKQLFYMINAVTLNNLLLRKDVCSWSTGMQLRYNISQLEEWLRGRNLHQSGAVQTMEPL
IQAAQLLQLKKKTQEDAEAICSLCTSLSTQQIVKILNLYTPLNEFEERVTVAFIRTIQAQ
LQERNDPQQLLLDAKHMFPVLFPFNPSSLTMDSIHIPACLNLEFLNEV
NT seq
5547 nt
NT seq
+upstream
nt +downstream
nt
atgtcggtgggcgagctctacagccagtgcacaagggtctggatccctgaccctgatgag
gtatggcgctcagctgagttaaccaaggactacaaagaaggagacaagagcctacagctc
agactggaggatgaaacgattctggaatacccaattgatgtacaacgcaaccagctgccc
ttcttacggaatccagatatcttggtgggagaaaatgacctgactgcccttagctatctt
catgagcctgcagttttgcataatttgaaggtccgtttcctggagtccaaccatatctac
acttactgtggtatcgtacttgttgccattaatccttatgaacagttgccaatctatgga
caagatgtcatctatacctacagtggccaaaacatgggagacatggacccccacatcttt
gctgtggcagaagaagcctacaagcagatggccagagatgagaagaatcagtccatcata
gtcagtggggagtctggagccgggaagacggtatcagccaagtatgccatgcgctatttc
gccaccgttggtggctcggccagtgaaaccaacatcgaagagaaggtgctggcatccagt
cccatcatggaggccattggaaatgccaagaccacccgcaatgacaacagcagccgtttt
ggcaagtacatccagattggctttgacaaaaggtaccacatcatcggggccaacatgagg
acttacctcttggagaagtccagagtggtcttccaggcagatgatgagaggaattaccac
atcttttaccagctctgtgctgctgccggtcttccagaatttaaagagcttgcactaaca
agtgcagaggactttttctatacatcacagggaggagacacttccatcgagggtgtggac
gatgctgaggactttgagaagactcgacaagccttcacactcctcggagtgaaagagtcc
catcagatgagcatttttaagataattgcttctatcttgcaccttggaagtgtggcgatt
caggctgagcgtgatggtgattcctgtagtatatcaccccaggatgtatacctaagcaac
ttctgccgactgctaggggtggagcacagtcagatggagcactggctgtgtcatcgcaag
ctggtcaccacctcggagacctacgtcaagaccatgtccctgcagcaggtgatcaatgcg
cgcaacgccctggcgaagcacatctatgcccagttgttcggctggattgtggagcacatc
aacaaggccctgcacacctccctcaagcagcactccttcatcggggtcctggacatctat
gggtttgagacatttgaggtaaacagctttgagcagttctgtatcaactatgcaaatgaa
aagctccagcagcagttcaactcgcatgttttcaaactggagcaagaagaatacatgaag
gaacagatcccttggaccctgattgatttttatgataaccaaccttgtatcgacctcatt
gaagccaagctgggtatcttggacctgttggatgaagaatgtaaggtccccaaaggaact
gaccagaactgggctcagaagctctatgaccggcactccagcagccagcacttccagaag
ccccgcatgtccaacacggccttcatcatcgtccactttgcagacaaggtggagtacctc
tctgatggttttctggagaaaaacagagacacggtgtatgaagagcagatcaatatcctg
aaggccagcaagttcccactagtggctgacttgtttcatgatgacaaggaccctgttcct
gccaccacccctgggaaggggtcatcttcgaagatcagcgtccgttctgccagacccccc
atgaaagtctccaacaaggagcacaagaaaaccgttggccaccagttccgtacctccctg
catctgctcatggagaccctgaatgccacgacacctcactatgtccgctgcatcaagccc
aacgatgagaagctcccctttcactttgacccaaagagagcagtgcagcaactcagagcc
tgcggggtgttggagacgattcgaatcagtgcagctggctacccatccaggtgggcctac
catgactttttcaaccggtatcgggtgctggtcaagaagagagagctcgccaacacagac
aaaaaggccatctgcaggtctgtcctggagaacctcatcaaggaccccgacaagttccag
tttggccgcaccaagatcttctttcgagcaggccaggtggcctacctggagaagctgcgg
gctgacaagttccggacagccaccatcatgatccagaaaactgtccggggatggctgcag
aaggtgaaatatcacaggctgaagggggctaccttaaccctgcagaggtactgccgggga
cacctggcccgcaggctggctgagcacctgcggaggatcagagcggctgtggtgctccag
aaacattaccgcatgcagagggcccgccaggcctaccagagggtccgcagagctgccgtt
gttatccaggccttcacccgggccatgtttgtgcggagaacctaccgccaggtcctcatg
gagcacaaggccaccaccatccagaagcacgtgcggggctggatggcacgcaggcacttc
cagcggctgcgggatgcagccattgtcatccagtgtgccttccggatgctcaaggccagg
cgggagctgaaggccctcaggattgaggcccgctcagcagagcatctgaaacgtctcaac
gtgggcatggagaacaaggtggtccagctgcagcggaagatcgatgagcagaacaaagag
ttcaagacactttcagagcagttgtccgtgaccacctcaacatacaccatggaggtagag
cggctgaagaaggagctggtgcactaccagcagagcccaggtgaggacaccagcctcagg
ctgcaggaggaggtggagagcctgcgcacagagctgcagagggcccactcggagcgcaag
atcttggaggacgcccacagcagggagaaagatgagctgaggaagcgagttgcagacctg
gagcaagaaaatgctctcttgaaagatgagaaagaacagctcaacaaccaaatcctgtgc
cagtctaaagatgaatttgcccagaactctgtgaaggaaaatctcatgaagaaagaactg
gaggaggagcgatcccggtaccagaaccttgtgaaggaatattcacagttggagcagaga
tacgacaaccttcgggatgaaatgaccatcataaagcaaactccaggtcataggcggaac
ccatcaaaccaaagtagcttagaatctgactccaattacccctccatctccacatctgag
atcggagacactgaggatgccctccagcaggtggaggaaattggcctggagaaggcagcc
atggacatgacggtcttcctgaagctgcagaagagagtacgggagctggagcaggagagg
aaaaagctgcaagtgcagctggagaagagagaacagcaggacagcaagaaagtccaggcg
gaaccaccacagactgacatagatttggacccgaatgcagatctggcctacaatagtctg
aagaggcaagagctggagtcagagaacaaaaagctgaagaatgacctgaatgagctgagg
aaagccgtggccgaccaagccacgcagaataactccagccacggctccccagatagctac
agcctcctgctgaaccagctcaagctggcccacgaggagctcgaggtgcgcaaggaggag
gtgctcatcctcaggacccagatcgtgagcgccgaccagcggcgactcgccggcaggaac
gcggagccgaacattaatgccagatcaagttggcctaacagtgaaaagcatgttgaccag
gaggatgccattgaggcctatcacggggtctgccagacaaacagcaagactgaggattgg
ggatatttaaatgaagatggagaactcggcttggcctaccaaggcctaaagcaagttgcc
aggctgctggaggctcagctgcaggcccagagcctggagcatgaggaggaggtggagcat
ctcaaggctcagctcgaggccctgaaggaggagatggacaaacagcagcagaccttctgc
cagacgctactgctctccccagaggcccaggtggaattcggcgttcagcaggaaatatcc
cggctgaccaacgagaatctggaccttaaagaactggtagaaaagctggaaaagaatgag
aggaagctcaaaaagcaactgaagatttacatgaagaaagcccaggacctagaagctgcc
caggcattggcccagagtgagaggaagcgccatgagctcaacaggcaggtcacggtccag
cggaaagagaaggatttccagggcatgctggagtaccacaaagaggacgaggccctcctc
atccggaacctggtgacagacttgaagccccagatgctgtcgggcacagtgccctgtctc
cccgcctacatcctctacatgtgcatccggcacgcggactacaccaacgacgatctcaag
gtgcactccctgctgacctccaccatcaacggcattaagaaagtcctgaaaaagcacaat
gatgactttgagatgacgtcattctggttatccaacacctgccgccttcttcactgtctg
aagcagtacagcggggatgagggcttcatgactcagaacactgcaaagcagaatgaacac
tgtcttaagaattttgacctcaccgaataccgtcaggtgctgagtgacctttccattcag
atctaccagcagctcattaaaattgccgagggcgtgttacagccgatgatagtttctgcc
atgttggaaaatgagagcattcagggtctatctggtgtgaagcccaccggctaccggaag
cgctcctccagcatggcagatggggataactcatactgcctggaagctatcatccgccag
atgaatgcctttcatacagtcatgtgtgaccagggcttggaccctgagatcatcctgcag
gtattcaaacagctcttctacatgatcaacgcagtgactcttaacaacctgctcttgcgg
aaggacgtctgctcttggagcacaggcatgcaactcaggtacaatataagtcagcttgag
gagtggcttcggggaagaaaccttcaccagagtggagcagttcagaccatggaacctctg
atccaagcagcccagctcctgcaattaaagaagaaaacccaggaggacgcagaggctatc
tgctccctgtgtacctccctcagcacccagcagattgtcaaaattttaaacctttatact
cccctgaatgaatttgaagaacgggtaacagtggcctttatacgaacaatccaggcacaa
ctacaagagcggaatgaccctcagcaactgctattagatgccaagcacatgtttcctgtt
ttgtttccatttaatccatcttctctaaccatggactcaatccacatcccagcgtgtctc
aatctggaattcctcaatgaagtctga
Homo sapiens (human): 815
Help
Entry
815 CDS
T01001
Symbol
CAMK2A, CAMKA, CaMKIINalpha, CaMKIIalpha, MRD53, MRT63
Name
(RefSeq) calcium/calmodulin dependent protein kinase II alpha
KO
K04515
calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:
2.7.11.17
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04012
ErbB signaling pathway
hsa04020
Calcium signaling pathway
hsa04024
cAMP signaling pathway
hsa04066
HIF-1 signaling pathway
hsa04114
Oocyte meiosis
hsa04148
Efferocytosis
hsa04217
Necroptosis
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04310
Wnt signaling pathway
hsa04360
Axon guidance
hsa04713
Circadian entrainment
hsa04720
Long-term potentiation
hsa04722
Neurotrophin signaling pathway
hsa04725
Cholinergic synapse
hsa04728
Dopaminergic synapse
hsa04740
Olfactory transduction
hsa04750
Inflammatory mediator regulation of TRP channels
hsa04911
Insulin secretion
hsa04912
GnRH signaling pathway
hsa04916
Melanogenesis
hsa04921
Oxytocin signaling pathway
hsa04922
Glucagon signaling pathway
hsa04925
Aldosterone synthesis and secretion
hsa04934
Cushing syndrome
hsa04971
Gastric acid secretion
hsa05012
Parkinson disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05031
Amphetamine addiction
hsa05152
Tuberculosis
hsa05200
Pathways in cancer
hsa05205
Proteoglycans in cancer
hsa05214
Glioma
hsa05415
Diabetic cardiomyopathy
hsa05417
Lipid and atherosclerosis
Network
nt06220
Calcium signaling (cancer)
nt06273
Glioma
nt06316
Renin-angiotensin-aldosterone signaling
nt06528
Calcium signaling
nt06535
Efferocytosis
nt06541
Cytoskeleton in neurons
Element
N00026
EGF-EGFR-PLCG-CAMK signaling pathway
N00027
Amplified EGFR to PLCG-CAMK signaling pathway
N00028
PDGF-PDGFR-PLCG-CAMK signaling pathway
N00029
Amplified PDGFR to PLCG-CAMK signaling pathway
N00301
Angiotensin-aldosterone signaling pathway
N00302
Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303
Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304
Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305
Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N01648
Ca2+/CAM-CAMK signaling pathway
N01775
Inactivation of CaMKII by inducing SERCA2
N01776
CaMK2-p38-MK2-ALOX5 pathway
N01850
MYO5B-mediated vesicle transport
Disease
H00768
Autosomal recessive intellectual developmental disorder
H00773
Autosomal dominant intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
815 (CAMK2A)
04310 Wnt signaling pathway
815 (CAMK2A)
04066 HIF-1 signaling pathway
815 (CAMK2A)
04020 Calcium signaling pathway
815 (CAMK2A)
04024 cAMP signaling pathway
815 (CAMK2A)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
815 (CAMK2A)
09143 Cell growth and death
04114 Oocyte meiosis
815 (CAMK2A)
04217 Necroptosis
815 (CAMK2A)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
815 (CAMK2A)
04922 Glucagon signaling pathway
815 (CAMK2A)
04912 GnRH signaling pathway
815 (CAMK2A)
04921 Oxytocin signaling pathway
815 (CAMK2A)
04916 Melanogenesis
815 (CAMK2A)
04925 Aldosterone synthesis and secretion
815 (CAMK2A)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
815 (CAMK2A)
09154 Digestive system
04971 Gastric acid secretion
815 (CAMK2A)
09156 Nervous system
04725 Cholinergic synapse
815 (CAMK2A)
04728 Dopaminergic synapse
815 (CAMK2A)
04720 Long-term potentiation
815 (CAMK2A)
04722 Neurotrophin signaling pathway
815 (CAMK2A)
09157 Sensory system
04740 Olfactory transduction
815 (CAMK2A)
04750 Inflammatory mediator regulation of TRP channels
815 (CAMK2A)
09158 Development and regeneration
04360 Axon guidance
815 (CAMK2A)
09159 Environmental adaptation
04713 Circadian entrainment
815 (CAMK2A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
815 (CAMK2A)
05205 Proteoglycans in cancer
815 (CAMK2A)
09162 Cancer: specific types
05214 Glioma
815 (CAMK2A)
09171 Infectious disease: bacterial
05152 Tuberculosis
815 (CAMK2A)
09164 Neurodegenerative disease
05012 Parkinson disease
815 (CAMK2A)
05022 Pathways of neurodegeneration - multiple diseases
815 (CAMK2A)
09165 Substance dependence
05031 Amphetamine addiction
815 (CAMK2A)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
815 (CAMK2A)
05415 Diabetic cardiomyopathy
815 (CAMK2A)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
815 (CAMK2A)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
815 (CAMK2A)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.17 Ca2+/calmodulin-dependent protein kinase
815 (CAMK2A)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CAMK group
CAMK2 family
815 (CAMK2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
CaMKII_AD
PK_Tyr_Ser-Thr
DUF4440
SnoaL_3
SnoaL_2
SnoaL_4
Kdo
Motif
Other DBs
NCBI-GeneID:
815
NCBI-ProteinID:
NP_001350919
OMIM:
114078
HGNC:
1460
Ensembl:
ENSG00000070808
UniProt:
Q9UQM7
Q7LDD5
Structure
PDB
PDBj
LinkDB
All DBs
Position
5:complement(150219491..150290130)
Genome browser
AA seq
478 aa
AA seq
DB search
MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE
ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL
EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL
SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV
TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
GAILTTMLATRNFSGGKSGGNKKSDGVKESSESTNTTIEDEDTKVRKQEIIKVTEQLIEA
ISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKPVHTTILNPHIH
LMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHRSGAPSVLPH
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
atggccaccatcacctgcacccgcttcacggaagagtaccagctcttcgaggaattgggc
aagggagccttctcggtggtgcgaaggtgtgtgaaggtgctggctggccaggagtatgct
gccaagatcatcaacacaaagaagctgtcagccagagaccatcagaagctggagcgtgaa
gcccgcatctgccgcctgctgaagcaccccaacatcgtccgactacatgacagcatctca
gaggagggacaccactacctgatcttcgacctggtcactggtggggaactgtttgaagat
atcgtggcccgggagtattacagtgaggcggatgccagtcactgtatccagcagatcctg
gaggctgtgctgcactgccaccagatgggggtggtgcaccgggacctgaagcctgagaat
ctgttgctggcctccaagctcaagggtgccgcagtgaagctggcagactttggcctggcc
atagaggtggagggggagcagcaggcatggtttgggtttgcagggactcctggatatctc
tccccagaagtgctgcggaaggacccgtacgggaagcctgtggacctgtgggcttgtggg
gtcatcctgtacatcctgctggttgggtaccccccgttctgggatgaggaccagcaccgc
ctgtaccagcagatcaaagccggcgcctatgatttcccatcgccggaatgggacactgtc
accccggaagccaaggatctgatcaataagatgctgaccattaacccatccaaacgcatc
acagctgccgaagcccttaagcacccctggatctcgcaccgctccaccgtggcatcctgc
atgcacagacaggagaccgtggactgcctgaagaagttcaatgccaggaggaaactgaag
ggagccattctcaccacgatgctggccaccaggaacttctccggagggaagagtggggga
aacaagaagagcgatggtgtgaaggaatcctcagagagcaccaacaccaccatcgaggat
gaagacaccaaagtgcggaaacaggaaattataaaagtgacagagcagctgattgaagcc
ataagcaatggagattttgagtcctacacgaagatgtgcgaccctggcatgacagccttc
gaacctgaggccctggggaacctggttgagggcctggacttccatcgattctattttgaa
aacctgtggtcccggaacagcaagcccgtgcacaccaccatcctgaatccccacatccac
ctgatgggcgacgagtcagcctgcatcgcctacatccgcatcacgcagtacctggacgct
ggcggcatcccacgcaccgcccagtcggaggagacccgtgtctggcaccgccgggatggc
aaatggcagatcgtccacttccacagatctggggcgccctccgtcctgccccactga
Homo sapiens (human): 816
Help
Entry
816 CDS
T01001
Symbol
CAMK2B, CAM2, CAMK2, CAMKB, CaMKIIbeta, MRD54
Name
(RefSeq) calcium/calmodulin dependent protein kinase II beta
KO
K04515
calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:
2.7.11.17
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04012
ErbB signaling pathway
hsa04020
Calcium signaling pathway
hsa04024
cAMP signaling pathway
hsa04066
HIF-1 signaling pathway
hsa04114
Oocyte meiosis
hsa04148
Efferocytosis
hsa04217
Necroptosis
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04310
Wnt signaling pathway
hsa04360
Axon guidance
hsa04713
Circadian entrainment
hsa04720
Long-term potentiation
hsa04722
Neurotrophin signaling pathway
hsa04725
Cholinergic synapse
hsa04728
Dopaminergic synapse
hsa04740
Olfactory transduction
hsa04750
Inflammatory mediator regulation of TRP channels
hsa04911
Insulin secretion
hsa04912
GnRH signaling pathway
hsa04916
Melanogenesis
hsa04921
Oxytocin signaling pathway
hsa04922
Glucagon signaling pathway
hsa04925
Aldosterone synthesis and secretion
hsa04934
Cushing syndrome
hsa04971
Gastric acid secretion
hsa05012
Parkinson disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05031
Amphetamine addiction
hsa05152
Tuberculosis
hsa05200
Pathways in cancer
hsa05205
Proteoglycans in cancer
hsa05214
Glioma
hsa05415
Diabetic cardiomyopathy
hsa05417
Lipid and atherosclerosis
Network
nt06220
Calcium signaling (cancer)
nt06273
Glioma
nt06316
Renin-angiotensin-aldosterone signaling
nt06528
Calcium signaling
nt06535
Efferocytosis
nt06541
Cytoskeleton in neurons
Element
N00026
EGF-EGFR-PLCG-CAMK signaling pathway
N00027
Amplified EGFR to PLCG-CAMK signaling pathway
N00028
PDGF-PDGFR-PLCG-CAMK signaling pathway
N00029
Amplified PDGFR to PLCG-CAMK signaling pathway
N00301
Angiotensin-aldosterone signaling pathway
N00302
Mutation-activated CACNA1D/H to angiotensin-aldosterone signaling pathway
N00303
Mutation-activated KCNJ5 to angiotensin-aldosterone signaling pathway
N00304
Mutation-inactivated ATP1A1 to angiotensin-aldosterone signaling pathway
N00305
Mutation-inactivated ATP2B3 to angiotensin-aldosterone signaling pathway
N01648
Ca2+/CAM-CAMK signaling pathway
N01775
Inactivation of CaMKII by inducing SERCA2
N01776
CaMK2-p38-MK2-ALOX5 pathway
N01850
MYO5B-mediated vesicle transport
Disease
H00773
Autosomal dominant intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
816 (CAMK2B)
04310 Wnt signaling pathway
816 (CAMK2B)
04066 HIF-1 signaling pathway
816 (CAMK2B)
04020 Calcium signaling pathway
816 (CAMK2B)
04024 cAMP signaling pathway
816 (CAMK2B)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
816 (CAMK2B)
09143 Cell growth and death
04114 Oocyte meiosis
816 (CAMK2B)
04217 Necroptosis
816 (CAMK2B)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
816 (CAMK2B)
04922 Glucagon signaling pathway
816 (CAMK2B)
04912 GnRH signaling pathway
816 (CAMK2B)
04921 Oxytocin signaling pathway
816 (CAMK2B)
04916 Melanogenesis
816 (CAMK2B)
04925 Aldosterone synthesis and secretion
816 (CAMK2B)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
816 (CAMK2B)
09154 Digestive system
04971 Gastric acid secretion
816 (CAMK2B)
09156 Nervous system
04725 Cholinergic synapse
816 (CAMK2B)
04728 Dopaminergic synapse
816 (CAMK2B)
04720 Long-term potentiation
816 (CAMK2B)
04722 Neurotrophin signaling pathway
816 (CAMK2B)
09157 Sensory system
04740 Olfactory transduction
816 (CAMK2B)
04750 Inflammatory mediator regulation of TRP channels
816 (CAMK2B)
09158 Development and regeneration
04360 Axon guidance
816 (CAMK2B)
09159 Environmental adaptation
04713 Circadian entrainment
816 (CAMK2B)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
816 (CAMK2B)
05205 Proteoglycans in cancer
816 (CAMK2B)
09162 Cancer: specific types
05214 Glioma
816 (CAMK2B)
09171 Infectious disease: bacterial
05152 Tuberculosis
816 (CAMK2B)
09164 Neurodegenerative disease
05012 Parkinson disease
816 (CAMK2B)
05022 Pathways of neurodegeneration - multiple diseases
816 (CAMK2B)
09165 Substance dependence
05031 Amphetamine addiction
816 (CAMK2B)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
816 (CAMK2B)
05415 Diabetic cardiomyopathy
816 (CAMK2B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
816 (CAMK2B)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
816 (CAMK2B)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.17 Ca2+/calmodulin-dependent protein kinase
816 (CAMK2B)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CAMK group
CAMK2 family
816 (CAMK2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
CaMKII_AD
PK_Tyr_Ser-Thr
DUF4440
SnoaL_3
SnoaL_2
Pkinase_fungal
SnoaL_4
Kdo
DUF7171
Motif
Other DBs
NCBI-GeneID:
816
NCBI-ProteinID:
NP_001211
OMIM:
607707
HGNC:
1461
Ensembl:
ENSG00000058404
UniProt:
Q13554
A4D2J9
Structure
PDB
PDBj
LinkDB
All DBs
Position
7:complement(44217154..44326013)
Genome browser
AA seq
666 aa
AA seq
DB search
MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER
EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI
LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY
LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT
VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL
KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK
NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKAPRVPDILSSVR
RGSGAPEAEGPLPCPSPAPFSPLPAPSPRISDILNSVRRGSGTPEAEGPLSAGPPPCLSP
ALLGPLSSPSPRISDILNSVRRGSGTPEAEGPSPVGPPPCPSPTIPGPLPTPSRKQEIIK
TTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHT
TILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGA
PVAPLQ
NT seq
2001 nt
NT seq
+upstream
nt +downstream
nt
atggccaccacggtgacctgcacccgcttcaccgacgagtaccagctctacgaggatatt
ggcaagggggctttctctgtggtccgacgctgtgtcaagctctgcaccggccatgagtat
gcagccaagatcatcaacaccaagaagctgtcagccagagatcaccagaagctggagaga
gaggctcggatctgccgccttctgaagcattccaacatcgtgcgtctccacgacagcatc
tccgaggagggcttccactacctggtcttcgatctggtcactggtggggagctctttgaa
gacattgtggcgagagagtactacagcgaggctgatgccagtcactgtatccagcagatc
ctggaggccgttctccattgtcaccaaatgggggtcgtccacagagacctcaagccggag
aacctgcttctggccagcaagtgcaaaggggctgcagtgaagctggcagacttcggccta
gctatcgaggtgcagggggaccagcaggcatggtttggtttcgctggcacaccaggctac
ctgtcccctgaggtccttcgcaaagaggcgtatggcaagcctgtggacatctgggcatgt
ggggtgatcctgtacatcctgctcgtgggctacccacccttctgggacgaggaccagcac
aagctgtaccagcagatcaaggctggtgcctatgacttcccgtcccctgagtgggacacc
gtcactcctgaagccaaaaacctcatcaaccagatgctgaccatcaaccctgccaagcgc
atcacagcccatgaggccctgaagcacccgtgggtctgccaacgctccacggtagcatcc
atgatgcacagacaggagactgtggagtgtctgaaaaagttcaatgccaggagaaagctc
aagggagccatcctcaccaccatgctggccacacggaatttctcagtgggcagacagacc
accgctccggccacaatgtccaccgcggcctccggcaccaccatggggctggtggaacaa
gccaagagtttactcaacaagaaagcagatggagtcaagccccagacgaatagcaccaaa
aacagtgcagccgccaccagccccaaagggacgcttcctcctgccgccctggagcctcaa
accaccgtcatccataacccagtggacgggattaaggagtcttctgacagtgccaatacc
accatagaggatgaagacgctaaagcccccagggtccccgacatcctgagctcagtgagg
aggggctcgggagccccagaagccgaggggcccctgccctgcccatctccggctcccttt
agccccctgccagccccatcccccaggatctctgacatcctgaactctgtgagaaggggt
tcaggaaccccagaagccgagggccccctctcagcggggcccccgccctgcctgtctccg
gctctcctaggccccctgtcctccccgtcccccaggatctctgacatcctgaactctgtg
aggaggggctcagggaccccagaagccgagggcccctcgccagtggggcccccgccctgc
ccatctccgactatccctggccccctgcccaccccatcccggaagcaggagatcattaag
accacggagcagctcatcgaggccgtcaacaacggtgactttgaggcctacgcgaaaatc
tgtgacccagggctgacctcgtttgagcctgaagcactgggcaacctggttgaagggatg
gacttccacagattctacttcgagaacctgctggccaagaacagcaagccgatccacacg
accatcctgaacccacacgtgcacgtcattggagaggatgccgcctgcatcgcttacatc
cggctcacgcagtacattgacgggcagggccggccccgcaccagccagtctgaggagacc
cgcgtgtggcaccgccgcgacggcaagtggcagaacgtgcacttccactgctcgggcgcg
cctgtggccccgctgcagtga
Homo sapiens (human): 140735
Help
Entry
140735 CDS
T01001
Symbol
DYNLL2, DNCL1B, Dlc2, RSPH22
Name
(RefSeq) dynein light chain LC8-type 2
KO
K10418
dynein light chain LC8-type
Organism
hsa
Homo sapiens (human)
Pathway
hsa04517
IgSF CAM signaling
hsa04814
Motor proteins
hsa04962
Vasopressin-regulated water reabsorption
hsa05132
Salmonella infection
Network
nt06181
Salmonella
nt06515
Regulation of kinetochore-microtubule interactions
nt06541
Cytoskeleton in neurons
Element
N01295
Rab7-regulated microtubule minus-end directed transport
N01534
Dynein recruitment to the kinetochore
N01846
Retrograde axonal/dendrite transport, Dynein
N01847
Regulation of dynein-mediated retrograde transport
N01850
MYO5B-mediated vesicle transport
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
140735 (DYNLL2)
09140 Cellular Processes
09142 Cell motility
04814 Motor proteins
140735 (DYNLL2)
09150 Organismal Systems
09155 Excretory system
04962 Vasopressin-regulated water reabsorption
140735 (DYNLL2)
09160 Human Diseases
09171 Infectious disease: bacterial
05132 Salmonella infection
140735 (DYNLL2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
03037 Cilium and associated proteins [BR:
hsa03037
]
140735 (DYNLL2)
04812 Cytoskeleton proteins [BR:
hsa04812
]
140735 (DYNLL2)
Cilium and associated proteins [BR:
hsa03037
]
Motile cilia and associated proteins
Dynein arm
140735 (DYNLL2)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
Dyneins
140735 (DYNLL2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dynein_light
Nop
SpoIIIAH
Ectatomin
Motif
Other DBs
NCBI-GeneID:
140735
NCBI-ProteinID:
NP_542408
OMIM:
608942
HGNC:
24596
Ensembl:
ENSG00000264364
UniProt:
Q96FJ2
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:58083419..58095542
Genome browser
AA seq
89 aa
AA seq
DB search
MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGR
NFGSYVTHETKHFIYFYLGQVAILLFKSG
NT seq
270 nt
NT seq
+upstream
nt +downstream
nt
atgtctgaccggaaggcagtgatcaagaacgcagacatgtctgaggacatgcaacaggat
gccgttgactgcgccacgcaggccatggagaagtacaatatagagaaggacattgctgcc
tatatcaagaaggaatttgacaagaaatataaccctacctggcattgtatcgtgggccga
aattttggcagctacgtcacacacgagacaaagcacttcatctatttttacttgggtcaa
gttgcaatcctcctcttcaagtcaggctag
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integrated database retrieval system
