Homo sapiens (human): 4891 Help Entry 4891              CDS       T01001                                  Symbol SLC11A2, AHMIO1, DCT1, DMT1, NRAMP2 Name (RefSeq) solute carrier family 11 member 2   KO K21398   natural resistance-associated macrophage protein 2 Organism hsa  Homo sapiens (human) Pathway hsa04142   Lysosome hsa04216   Ferroptosis hsa04978   Mineral absorption hsa05010   Alzheimer disease hsa05012   Parkinson disease Network nt06525  Ferroptosis   Element N01587   Fe-TF transport Disease H01196   Hypochromic microcytic anemia Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04142 Lysosome     4891 (SLC11A2)   09143 Cell growth and death    04216 Ferroptosis     4891 (SLC11A2)  09150 Organismal Systems   09154 Digestive system    04978 Mineral absorption     4891 (SLC11A2)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     4891 (SLC11A2)    05012 Parkinson disease     4891 (SLC11A2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    02000 Transporters [BR:hsa02000]     4891 (SLC11A2) Transporters [BR:hsa02000]  Solute carrier family (SLC)   SLC11: Proton-coupled metal ion transporter    4891 (SLC11A2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Nramp Motif Other DBs NCBI-GeneID:  4891 NCBI-ProteinID:  NP_001167597 OMIM:  600523 HGNC:  10908 Ensembl:  ENSG00000110911 UniProt:  P49281 A0A0X8GKR4 Structure PDB LinkDB All DBs Position 12:complement(50952263..51028886) Genome browser AA seq 568 aa AA seqDB search MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEE EYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQR LAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRI PLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGM FVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIES CIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGG VVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAI IPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAG GILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDC GHTCHLGLTAQPELYLLNTMDADSLVSR NT seq 1707 nt NT seq  +upstreamnt  +downstreamnt atggtgctgggtcctgaacagaagatgtcagatgacagtgtttctggagatcatggggag tctgccagtcttggtaacatcaaccctgcctatagtaatccctctctttcacagtcccct ggggactcagaggagtacttcgccacttactttaatgagaagatctccattcctgaggag gagtactcttgttttagctttcgtaaactctgggctttcaccggaccaggttttcttatg agcattgcctacctggatccaggaaatattgaatccgatttgcagtctggagcagtggct ggatttaagttgctctggatccttctgttggccacccttgtggggctgctgctccagcgg cttgcagctagactgggagtggttactgggctgcatcttgctgaagtatgtcaccgtcag tatcccaaggtcccacgagtcatcctgtggctgatggtggagttggctatcatcggctca gacatgcaagaagtcattggctcagccattgctatcaatcttctgtctgtaggaagaatt cctctgtggggtggcgttctcatcaccattgcagatacttttgtatttctcttcttggac aaatatggcttgcggaagctagaagcattttttggctttctcatcactattatggccctc acatttggatatgagtatgttacagtgaaacccagccagagccaggtactcaagggcatg ttcgtaccatcctgttcaggctgtcgcactccacagattgaacaggctgtgggcatcgtg ggagctgtcatcatgccacacaacatgtacctgcattctgccttagtcaagtctagacag gtaaaccggaacaataagcaggaagttcgagaagccaataagtactttttcattgaatcc tgcattgcactctttgtttccttcatcatcaatgtctttgttgtctcagtctttgctgaa gcattttttgggaaaaccaacgagcaggtggttgaagtctgtacaaataccagcagtcct catgctggcctctttcctaaagataactcgacactggctgtggacatctacaaagggggt gttgtgctgggatgttactttgggcctgctgcactctacatttgggcagtggggatcctg gctgcaggacagagctccaccatgacaggaacctattctggccagtttgtcatggaggga ttcctgaacctaaagtggtcacgctttgcccgagtggttctgactcgctctattgccatc atccccactctgcttgttgctgtcttccaagatgtagagcatctaacagggatgaatgac tttctgaatgttctacagagcttacagcttccctttgctctcatacccatcctcacattt acgagcttgcggccagtaatgagtgactttgccaatggactaggctggcggattgcagga ggaatcttggtccttatcatctgttccatcaatatgtactttgtagtggtttatgtccgg gacctagggcatgtggcattatatgtggtggctgctgtggtcagcgtggcttatctgggc tttgtgttctacttgggttggcaatgtttgattgcactgggcatgtccttcctggactgt gggcatacgtgccatctgggattgacagctcagcctgaactctatcttctgaacaccatg gacgctgactcacttgtgtctagatga

Homo sapiens (human): 6556 Help Entry 6556              CDS       T01001                                  Symbol SLC11A1, LSH, NRAMP, NRAMP1 Name (RefSeq) solute carrier family 11 member 1   KO K12347   natural resistance-associated macrophage protein 1 Organism hsa  Homo sapiens (human) Pathway hsa04142   Lysosome Disease H00342   Tuberculosis Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04142 Lysosome     6556 (SLC11A1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    02000 Transporters [BR:hsa02000]     6556 (SLC11A1) Transporters [BR:hsa02000]  Solute carrier family (SLC)   SLC11: Proton-coupled metal ion transporter    6556 (SLC11A1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Nramp DUF5765 Motif Other DBs NCBI-GeneID:  6556 NCBI-ProteinID:  NP_000569 OMIM:  600266 HGNC:  10907 Ensembl:  ENSG00000018280 UniProt:  P49279 LinkDB All DBs Position 2:218382273..218396894 Genome browser AA seq 550 aa AA seqDB search MTGDKGPQRLSGSSYGSISSPTSPTSPGPQQAPPRETYLSEKIPIPDTKPGTFSLRKLWA FTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKD LGEVCHLYYPKVPRTVLWLTIELAIVGSDMQEVIGTAIAFNLLSAGRIPLWGGVLITIVD TFFFLFLDNYGLRKLEAFFGLLITIMALTFGYEYVVARPEQGALLRGLFLPSCPGCGHPE LLQAVGIVGAIIMPHNIYLHSALVKSREIDRARRADIREANMYFLIEATIALSVSFIINL FVMAVFGQAFYQKTNQAAFNICANSSLHDYAKIFPMNNATVAVDIYQGGVILGCLFGPAA LYIWAIGLLAAGQSSTMTGTYAGQFVMEGFLRLRWSRFARVLLTRSCAILPTVLVAVFRD LRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPTLMQEFANGLLNKVVTSSIMVLVCAIN LYFVVSYLPSLPHPAYFGLAALLAAAYLGLSTYLVWTCCLAHGATFLAHSSHHHFLYGLL EEDQKGETSG NT seq 1653 nt NT seq  +upstreamnt  +downstreamnt atgacaggtgacaagggtccccaaaggctaagcgggtccagctatggttccatctccagc ccgaccagcccgaccagcccagggccacagcaagcacctcccagagagacctacctgagt gagaagatccccatcccagacacaaaaccgggcaccttcagcctgcggaagctatgggcc ttcacggggcctggcttcctcatgagcattgctttcctggacccaggaaacatcgagtca gatcttcaggctggcgccgtggcgggattcaaacttctctgggtgctgctctgggccacc gtgttgggcttgctctgccagcgactggctgcacgtctgggcgtggtgacaggcaaggac ttgggcgaggtctgccatctctactaccctaaggtgccccgcaccgtcctctggctgacc atcgagctagccattgtgggctccgacatgcaggaagtcatcggcacggccattgcattc aatctgctctcagctggacgaatcccactctggggtggcgtcctcatcaccatcgtggac accttcttcttcctcttcctcgataactacgggctgcggaagctggaagctttttttgga ctccttataaccattatggccttgacctttggctatgagtatgtggtggcgcgtcctgag cagggagcgcttcttcggggcctgttcctgccctcgtgcccgggctgcggccaccccgag ctgctgcaggcggtgggcattgttggcgccatcatcatgccccacaacatctacctgcac tcggccctggtcaagtctcgagagatagaccgggcccgccgagcagacatcagagaagcc aacatgtacttcctgattgaggccaccatcgccctgtccgtctcctttatcatcaacctc tttgtcatggctgtctttgggcaggccttctaccagaaaaccaaccaggctgcgttcaac atctgtgccaacagcagcctccacgactacgccaagatcttccccatgaacaacgccacc gtggccgtggacatttaccaggggggcgtgatcctgggctgcctgttcggccccgcggcc ctctacatctgggccataggtctcctggcggctgggcagagctccaccatgacgggcacc tacgcgggacagttcgtgatggagggcttcctgaggctgcggtggtcacgcttcgcccgt gtcctcctcacccgctcctgcgccatcctgcccaccgtgctcgtggctgtcttccgggac ctgagggacttgtcgggcctcaatgatctgctcaacgtgctgcagagcctgctgctcccg ttcgccgtgctgcccatcctcacgttcaccagcatgcccaccctcatgcaggagtttgcc aatggcctgctgaacaaggtcgtcacctcttccatcatggtgctagtctgcgccatcaac ctctacttcgtggtcagctatctgcccagcctgccccaccctgcctacttcggccttgca gccttgctggccgcagcctacctgggcctcagcacctacctggtctggacctgttgcctt gcccacggagccacctttctggcccacagctcccaccaccacttcctgtatgggctcctt gaagaggaccagaaaggggagacctctggctag

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