KEGG T01001: 51013

Homo sapiens (human): 51013

Entry

51013             CDS       T01001

Symbol

EXOSC1, CGI-108, CSL4, Csl4p, PCH1F, SKI4, Ski4p, p13

Name

(RefSeq) exosome component 1

K07573

exosome complex component CSL4

Organism

hsa Homo sapiens (human)

Pathway

hsa03018

RNA degradation

Disease

H00897

Pontocerebellar hypoplasia

Brite

KEGG Orthology (KO) [BR:hsa00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    51013 (EXOSC1)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    51013 (EXOSC1)
Messenger RNA biogenesis [BR:hsa03019]
Eukaryotic type
  mRNA degradation factors
   3'-5' decay
    Core exosome factors
     51013 (EXOSC1)
Prokaryotic type
  Archeal mRNA degradation factors
   Exosome components
    Core exosome
     51013 (EXOSC1)

SSDB

Motif

Pfam:

EXOSC1 ECR1_N RRP4_S1 Nairovirus_NSm

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

10:complement(97435909..97446006)

AA seq 195 aa
MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETE
SQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYK
SFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTK
EFRKVARVQPEFLQT

NT seq 588 nt +upstreamnt +downstreamnt
atggcgccacctgtgagatactgcatccccggcgaacgtctgtgtaacttggaggagggc
agcccgggcagcggcacctacacccgccacggctacatcttttcgtcgcttgccggctgt
ctgatgaagagcagcgagaatggcgcgcttccagtggtgtctgtagtgagagaaacagag
tcccagttactgccagatgtgggagctattgtaacctgtaaggtctctagcatcaattca
cgctttgccaaagtacacatcctgtatgtggggtccatgcctcttaagaactcttttcga
ggaactatccgcaaggaagatgtccgagcaactgaaaaagacaaggttgaaatttataag
agtttccgcccaggtgacattgtcttggccaaagtgatctccttaggtgatgcacagtcc
aactacctgctaaccaccgccgagaacgagctgggagtggtggtagcccacagtgagtca
ggtatccagatggttcccatcagctggtgtgagatgcagtgccctaagacccacactaaa
gaattccggaaagtagcccgagtacaacccgaattcttgcagacctaa

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