Homo sapiens (human): 552 Help Entry 552               CDS       T01001                                  Symbol AVPR1A, AVPR_V1a, AVPR1, V1aR Name (RefSeq) arginine vasopressin receptor 1A   KO K04226   arginine vasopressin receptor 1A Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04072   Phospholipase D signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04270   Vascular smooth muscle contraction Drug target Balovaptan:  D11476 Conivaptan (DG00276):  D01236<US> D07748 Felypressin:  D04137 Lypressin:  D00366 Ornipressin:  D07227 Terlipressin (DG00498):  D06672 D08571 Vasopressin (Argipressin) (DG00496):  D00101<JP/US> D02983 D09820 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     552 (AVPR1A)    04072 Phospholipase D signaling pathway     552 (AVPR1A)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     552 (AVPR1A)  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     552 (AVPR1A)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     552 (AVPR1A) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Vasopressin     552 (AVPR1A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 V1R_C 7TM_GPCR_Srsx 7TM_GPCR_Srv 7tm_4 Motif Other DBs NCBI-GeneID:  552 NCBI-ProteinID:  NP_000697 OMIM:  600821 HGNC:  895 Ensembl:  ENSG00000166148 Vega:  OTTHUMG00000169980 Pharos:  P37288(Tclin) UniProt:  P37288 X5D2B0 Structure PDB LinkDB All DBs Position 12:complement(63142759..63151201) Genome browser AA seq 418 aa AA seqDB search MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST NT seq 1257 nt NT seq  +upstreamnt  +downstreamnt atgcgtctctccgccggtcccgacgcggggccctcgggcaactccagcccatggtggcct ctggccaccggcgctggcaacacaagccgggaggccgaagccctcggggagggcaacggc ccaccgagggacgtgcgcaacgaggagctggccaaactggagatcgccgtgctggcggtg actttcgcggtggccgtgctgggcaacagcagcgtactgctggctctgcaccggacgccg cgcaagacgtcccgcatgcacctcttcatccgacacctcagcctggccgacctggccgtg gcattcttccaggtgctgccgcaaatgtgctgggacatcacctaccgcttccgcggcccc gactggctgtgccgcgtggtgaagcacctgcaggtgttcggcatgtttgcgtcggcctac atgctggtagtcatgacagccgaccgctacatcgcggtgtgccacccgctcaagactctg caacagcccgcgcgccgctcgcgcctcatgatcgcggccgcctgggtgctgagcttcgtg ctgagcacgccgcagtacttcgtcttctccatgatcgaggtgaacaatgtcaccaaggcc cgcgactgctgggccaccttcatccagccctggggttctcgtgcctacgtgacctggatg acgggcggcatctttgtggcgcccgtggtcatcttgggtacctgctacggcttcatctgc tacaacatctggtgcaacgtccgcgggaagacggcgtcgcgccagagcaagggtgcagag caagcgggtgtggccttccaaaaggggttcctgctcgcaccctgtgtcagcagcgtgaag tccatttcccgggccaagatccgcacggtgaagatgacttttgtgatcgtgacggcttac atcgtctgctgggcgcctttcttcatcatccagatgtggtctgtctgggatcccatgtcc gtctggaccgaatcggaaaaccctaccatcaccatcactgcattactgggttccttgaat agctgctgtaatccctggatatacatgttttttagtggccatctccttcaagactgtgtt caaagcttcccatgctgccaaaacatgaaggaaaaattcaacaaagaagatactgacagt atgagcagaagacagactttttattctaacaatcgaagcccaacaaacagtacgggtatg tggaaggactcgcctaaatcttccaagtccatcaaattcattcctgtttcaacttga

Homo sapiens (human): 553 Help Entry 553               CDS       T01001                                  Symbol AVPR1B, AVPR3, V1bR, VPR3 Name (RefSeq) arginine vasopressin receptor 1B   KO K04227   arginine vasopressin receptor 1B Organism hsa  Homo sapiens (human) Pathway hsa04020   Calcium signaling pathway hsa04072   Phospholipase D signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04270   Vascular smooth muscle contraction Drug target Lypressin:  D00366 Ornipressin:  D07227 Terlipressin (DG00498):  D06672 D08571 Vasopressin (Argipressin) (DG00496):  D00101<JP/US> D02983 D09820 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04020 Calcium signaling pathway     553 (AVPR1B)    04072 Phospholipase D signaling pathway     553 (AVPR1B)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     553 (AVPR1B)  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     553 (AVPR1B)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     553 (AVPR1B) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Vasopressin     553 (AVPR1B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx V1R_C 7TM_GPCR_Srv 7tm_4 PTCRA Srg Motif Other DBs NCBI-GeneID:  553 NCBI-ProteinID:  NP_000698 OMIM:  600264 HGNC:  896 Ensembl:  ENSG00000198049 Vega:  OTTHUMG00000184377 Pharos:  P47901(Tclin) UniProt:  P47901 LinkDB All DBs Position 1:complement(206106936..206117388) Genome browser AA seq 424 aa AA seqDB search MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLG QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQ PRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAE TIIF NT seq 1275 nt NT seq  +upstreamnt  +downstreamnt atggattctgggcctctgtgggatgccaaccccacccctcggggcaccctctctgccccc aatgccacaacaccctggctgggccgggatgaggagctggccaaggtggagatcggagtc ctggccactgtcctggtgctggcgaccgggggcaacctggctgtgctgctgaccctgggc cagctgggccgcaagcgctcccgcatgcacctgttcgtgctgcacttagccctgacagac ctggccgtggcgctcttccaggtgctgccacagctgctgtgggacatcacctaccgcttc cagggccccgacctcctgtgcagggccgtcaagtacctgcaggtgctcagcatgtttgcc tccacctacatgctgctggccatgacgctggaccgctacctggctgtctgtcaccccctg cgcagcctccagcagccaggccagtccacctacctgctcatcgctgctccctggctgctg gccgccatcttcagcctccctcaagtcttcattttttccctgcgggaggtgatccagggc tcaggggtgctggactgctgggcagacttcggcttcccttgggggccacgggcctacctc acctggaccaccctggctatcttcgttctgccggtgaccatgctcacggcctgctacagc ctcatctgccatgagatctgtaaaaacctaaaagtcaagacacaggcctggcgggtggga ggagggggctggaggacttgggacaggccctcaccttccaccttagctgccaccactcgg gggctgccatctcgggtcagcagcatcaacaccatctcacgggccaagatccgaacagtg aagatgacctttgtcatcgtgctggcctacatcgcttgctgggctcccttcttcagtgtc cagatgtggtccgtgtgggacaagaatgcccctgatgaagattccaccaatgtggctttc accatctctatgcttttgggcaacctcaacagctgctgcaacccctggatctacatgggc ttcaacagccacctgttaccgcggcccctgcgtcaccttgcctgctgtgggggtccccag cccaggatgcgccggcggctctccgacggcagcctctcgagccgccacaccacgctgctg acccgctccagctgcccggccaccctcagcctcagcctcagcctaaccctcagtgggagg cccaggcctgaagagtcaccaagggacttggagctggcagatggggaaggcaccgctgag accatcatcttttag

Homo sapiens (human): 554 Help Entry 554               CDS       T01001                                  Symbol AVPR2, ADHR, DI1, DIR, DIR3, NDI, NDI1, V2R Name (RefSeq) arginine vasopressin receptor 2   KO K04228   arginine vasopressin receptor 2 Organism hsa  Homo sapiens (human) Pathway hsa04072   Phospholipase D signaling pathway hsa04080   Neuroactive ligand-receptor interaction hsa04962   Vasopressin-regulated water reabsorption Network nt06326  AVP signaling   Element N00915   AVP-V2R-PKA signaling pathway N00916   Mutation-inactivated AVP to AVP-V2R-PKA signaling pathway N00917   Mutation-activated AVPR2 to AVP-V2R-PKA signaling pathway Disease H00252   Congenital nephrogenic diabetes insipidus H01294   Nephrogenic syndrome of inappropriate antidiuresis H01682   Syndrome of inappropriate secretion of antidiuretic hormone H01683   Disorders of antidiuretic hormone (ADH) secretion Drug target Conivaptan (DG00276):  D01236<US> D07748 Desmopressin (DG00497):  D00291 D02235<JP/US> Lixivaptan:  D04752 Lypressin:  D00366 Mozavaptane hydrochloride:  D01855 Ornipressin:  D07227 Terlipressin (DG00498):  D06672 D08571 Tolvaptan (DG03074):  D01213<JP/US> D11659<JP> Vasopressin (Argipressin) (DG00496):  D00101<JP/US> D02983 D09820 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     554 (AVPR2)   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     554 (AVPR2)  09150 Organismal Systems   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     554 (AVPR2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     554 (AVPR2) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Vasopressin     554 (AVPR2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srv 7tm_4 Git3 Motif Other DBs NCBI-GeneID:  554 NCBI-ProteinID:  NP_000045 OMIM:  300538 HGNC:  897 Ensembl:  ENSG00000126895 Vega:  OTTHUMG00000024227 Pharos:  P30518(Tclin) UniProt:  P30518 Structure PDB LinkDB All DBs Position X:153902625..153907166 Genome browser AA seq 371 aa AA seqDB search MLMASTTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLA ALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQM VGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQ RNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLVPGP SERPGGRRRGRRTGSPGEGAHVSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEA PLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCARGRTPPSLGPQDESCTT ASSSLAKDTSS NT seq 1116 nt NT seq  +upstreamnt  +downstreamnt atgctcatggcgtccaccacttccgctgtgcctgggcatccctctctgcccagcctgccc agcaacagcagccaggagaggccactggacacccgggacccgctgctagcccgggcggag ctggcgctgctctccatagtctttgtggctgtggccctgagcaatggcctggtgctggcg gccctagctcggcggggccggcggggccactgggcacccatacacgtcttcattggccac ttgtgcctggccgacctggccgtggctctgttccaagtgctgccccagctggcctggaag gccaccgaccgcttccgtgggccagatgccctgtgtcgggccgtgaagtatctgcagatg gtgggcatgtatgcctcctcctacatgatcctggccatgacgctggaccgccaccgtgcc atctgccgtcccatgctggcgtaccgccatggaagtggggctcactggaaccggccggtg ctagtggcttgggccttctcgctccttctcagcctgccccagctcttcatcttcgcccag cgcaacgtggaaggtggcagcggggtcactgactgctgggcctgctttgcggagccctgg ggccgtcgcacctatgtcacctggattgccctgatggtgttcgtggcacctaccctgggt atcgccgcctgccaggtgctcatcttccgggagattcatgccagtctggtgccagggcca tcagagaggcctggggggcgccgcaggggacgccggacaggcagccccggtgagggagcc cacgtgtcagcagctgtggccaagactgtgaggatgacgctagtgattgtggtcgtctat gtgctgtgctgggcacccttcttcctggtgcagctgtgggccgcgtgggacccggaggca cctctggaaggggcgccctttgtgctactcatgttgctggccagcctcaacagctgcacc aacccctggatctatgcatctttcagcagcagcgtgtcctcagagctgcgaagcttgctc tgctgtgcccggggacgcaccccacccagcctgggtccccaagatgagtcctgcaccacc gccagctcctccctggccaaggacacttcatcgtga

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