Homo sapiens (human): 5688
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Entry
5688 CDS
T01001
Symbol
PSMA7, C6, HEL-S-276, HSPC, RC6-1, XAPC7
Name
(RefSeq) proteasome 20S subunit alpha 7
KO
K02731
20S proteasome subunit alpha 4 [EC:
3.4.25.1
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03050
Proteasome
hsa05010
Alzheimer disease
hsa05012
Parkinson disease
hsa05014
Amyotrophic lateral sclerosis
hsa05016
Huntington disease
hsa05017
Spinocerebellar ataxia
hsa05020
Prion disease
hsa05022
Pathways of neurodegeneration - multiple diseases
Network
nt06460
Alzheimer disease
nt06461
Huntington disease
nt06463
Parkinson disease
nt06464
Amyotrophic lateral sclerosis
nt06465
Prion disease
nt06466
Pathways of neurodegeneration
Element
N01029
26S proteasome-mediated protein degradation
N01030
Mutation-caused aberrant SNCA to 26S proteasome-mediated protein degradation
N01060
Mutation-caused aberrant Abeta to 26S proteasome-mediated protein degradation
N01061
Mutation-caused aberrant Htt to 26S proteasome-mediated protein degradation
N01144
Mutation-caused aberrant SOD1 to 26S proteasome-mediated protein degradation
N01145
Mutation-inactivated VCP to 26S proteasome-mediated protein degradation
N01146
Mutation-inactivated UBQLN2 to 26S proteasome-mediated protein degradation
N01197
Scrapie conformation PrPSc to 26S proteasome-mediated protein degradation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03050 Proteasome
5688 (PSMA7)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
5688 (PSMA7)
05012 Parkinson disease
5688 (PSMA7)
05014 Amyotrophic lateral sclerosis
5688 (PSMA7)
05016 Huntington disease
5688 (PSMA7)
05017 Spinocerebellar ataxia
5688 (PSMA7)
05020 Prion disease
5688 (PSMA7)
05022 Pathways of neurodegeneration - multiple diseases
5688 (PSMA7)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
5688 (PSMA7)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
5688 (PSMA7)
03051 Proteasome [BR:
hsa03051
]
5688 (PSMA7)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.25 Threonine endopeptidases
3.4.25.1 proteasome endopeptidase complex
5688 (PSMA7)
Peptidases and inhibitors [BR:
hsa01002
]
Threonine peptidases
Family T1: proteasome family
5688 (PSMA7)
Membrane trafficking [BR:
hsa04131
]
Endosome - Lysosome transport
Rab GTPases and associated proteins
Rab associated proteins
5688 (PSMA7)
Proteasome [BR:
hsa03051
]
Eukaryotic proteasome
Core particles (20S proteasome)
alpha type subunits
5688 (PSMA7)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Proteasome
Proteasome_A_N
DUF5069
Motif
Other DBs
NCBI-GeneID:
5688
NCBI-ProteinID:
NP_002783
OMIM:
606607
HGNC:
9536
Ensembl:
ENSG00000101182
UniProt:
O14818
A0A0K0K1K4
Structure
PDB
LinkDB
All DBs
Position
20:complement(62136733..62143394)
Genome browser
AA seq
248 aa
AA seq
DB search
MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVR
KICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQ
SNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEA
IETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEIEKYVAEIEKEKEENE
KKKQKKAS
NT seq
747 nt
NT seq
+upstream
nt +downstream
nt
atgagctacgaccgcgccatcaccgtcttctcgcccgacggccacctcttccaagtggag
tacgcgcaggaggccgtcaagaagggctcgaccgcggttggtgttcgaggaagagacatt
gttgttcttggtgtggagaagaagtcagtggccaaactgcaggatgaaagaacagtgcgg
aagatctgtgctttggatgacaacgtctgcatggcctttgcaggcctcaccgccgatgca
aggatagtcatcaacagggcccgggtggagtgccagagccaccggctgactgtggaggac
ccggtcactgtggagtacatcacccgctacatcgccagtctgaagcagcgttatacgcag
agcaatgggcgcaggccgtttggcatctctgccctcatcgtgggtttcgactttgatggc
actcctaggctctatcagactgacccctcgggcacataccatgcctggaaggccaatgcc
ataggtcggggtgccaagtcagtgcgcgagttcctggagaagaactatactgacgaagcc
attgaaacagatgatctgaccattaagctggtgatcaaggcactcctggaagtggttcag
tcaggtggcaaaaacattgaacttgctgtcatgaggcgagatcaatccctcaagatttta
aatcctgaagaaattgagaagtatgttgctgaaattgaaaaagaaaaagaagaaaacgaa
aagaagaaacaaaagaaagcatcatga
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integrated database retrieval system
