Homo sapiens (human): 5980
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Entry
5980 CDS
T01001
Symbol
REV3L, POLZ, REV3
Name
(RefSeq) REV3 like, DNA directed polymerase zeta catalytic subunit
KO
K02350
DNA polymerase zeta [EC:
2.7.7.7
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa01524
Platinum drug resistance
hsa03460
Fanconi anemia pathway
Network
nt06508
Interstrand crosslink repair
Element
N01465
Lesion bypass by TLS and DSB formation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09124 Replication and repair
03460 Fanconi anemia pathway
5980 (REV3L)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
5980 (REV3L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
hsa03400
]
5980 (REV3L)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
5980 (REV3L)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
TLS (translesion DNA synthesis) factors
B-family DNA polymerases
5980 (REV3L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DUF4683
DNA_pol_B
DNA_pol_B_exo1
zf-C4pol
Motif
Other DBs
NCBI-GeneID:
5980
NCBI-ProteinID:
NP_002903
OMIM:
602776
HGNC:
9968
Ensembl:
ENSG00000009413
LinkDB
All DBs
Position
6:complement(111299033..111483711)
Genome browser
AA seq
3130 aa
AA seq
DB search
MFSVRIVTADYYMASPLQGLDTCQSPLTQAPVKKVPVVRVFGATPAGQKTCLHLHGIFPY
LYVPYDGYGQQPESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKER
HFMKIYLYNPTMVKRICELLQSGAIMNKFYQPHEAHIPYLLQLFIDYNLYGMNLINLAAV
KFRKARRKSNTLHATGSCKNHLSGNSLADTLFRWEQDEIPSSLILEGVEPQSTCELEVDA
VAADILNRLDIEAQIGGNPGLQAIWEDEKQRRRNRNETSQMSQPESQDHRFVPATESEKK
FQKRLQEILKQNDFSVTLSGSVDYSDGSQEFSAELTLHSEVLSPEMLQCTPANMVEVHKD
KESSKGHTRHKVEEALINEEAILNLMENSQTFQPLTQRLSESPVFMDSSPDEALVHLLAG
LESDGYRGERNRMPSPCRSFGNNKYPQNSDDEENEPQIEKEEMELSLVMSQRWDSNIEEH
CAKKRSLCRNTHRSSTEDDDSSSGEEMEWSDNSLLLASLSIPQLDGTADENSDNPLNNEN
SRTHSSVIATSKLSVKPSIFHKDAATLEPSSSAKITFQCKHTSALSSHVLNKEDLIEDLS
QTNKNTEKGLDNSVTSFTNESTYSMKYPGSLSSTVHSENSHKENSKKEILPVSSCESSIF
DYEEDIPSVTRQVPSRKYTNIRKIEKDSPFIHMHRHPNENTLGKNSFNFSDLNHSKNKVS
SEGNEKGNSTALSSLFPSSFTENCELLSCSGENRTMVHSLNSTADESGLNKLKIRYEEFQ
EHKTEKPSLSQQAAHYMFFPSVVLSNCLTRPQKLSPVTYKLQPGNKPSRLKLNKRKLAGH
QETSTKSSETGSTKDNFIQNNPCNSNPEKDNALASDLTKTTRGAFENKTPTDGFIDCHFG
DGTLETEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTHNSKISLPHPMEIGESLDGTLK
SRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPL
KDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKKKTGKQQRTNNENIKRTLSFRKKR
SHAILSPPSPSYNAETEDCDLNYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEIM
AAAEKEAMLFKGPNVYKKTVNSRIGKTSRARAQIKKSKAKLANPSIVTKKRNKRNQTNKL
VDDGKKKPRAKQKTNEKGTSRKHTTLKDEKIKSQSGAEVKFVLKHQNVSEFASSSGGSQL
LFKQKDMPLMGSAVDHPLSASLPTGINAQQKLSGCFSSFLESKKSVDLQTFPSSRDDLHP
SVVCNSIGPGVSKINVQRPHNQSAMFTLKESTLIQKNIFDLSNHLSQVAQNTQISSGMSS
KIEDNANNIQRNYLSSIGKLSEYRNSLESKLDQAYTPNFLHCKDSQQQIVCIAEQSKHSE
TCSPGNTASEESQMPNNCFVTSLRSPIKQIAWEQKQRGFILDMSNFKPERVKPRSLSEAI
SQTKALSQCKNRNVSTPSAFGEGQSGLAVLKELLQKRQQKAQNANTTQDPLSNKHQPNKN
ISGSLEHNKANKRTRSVTSPRKPRTPRSTKQKEKIPKLLKVDSLNLQNSSQLDNSVSDDS
PIFFSDPGFESCYSLEDSLSPEHNYNFDINTIGQTGFCSFYSGSQFVPADQNLPQKFLSD
AVQDLFPGQAIEKNEFLSHDNQKCDEDKHHTTDSASWIRSGTLSPEIFEKSTIDSNENRR
HNQWKNSFHPLTTRSNSIMDSFCVQQAEDCLSEKSRLNRSSVSKEVFLSLPQPNNSDWIQ
GHTRKEMGQSLDSANTSFTAILSSPDGELVDVACEDLELYVSRNNDMLTPTPDSSPRSTS
SPSQSKNGSFTPRTANILKPLMSPPSREEIMATLLDHDLSETIYQEPFCSNPSDVPEKPR
EIGGRLLMVETRLANDLAEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRSGQGVVNKGS
SNSPKMVEDKKIVIMPCKCAPSRQLVQVWLQAKEEYERSKKLPKTKPTGVVKSAENFSSS
VNPDDKPVVPPKMDVSPCILPTTAHTKEDVDNSQIALQAPTTGCSQTASESQMLPPVASA
SDPEKDEDDDDNYYISYSSPDSPVIPPWQQPISPDSKALNGDDRPSSPVEELPSLAFENF
LKPIKDGIQKSPCSEPQEPLVISPINTRARTGKCESLCFHSTPIIQRKLLERLPEAPGLS
PLSTEPKTQKLSNKKGSNTDTLRRVLLTQAKNQFAAVNTPQKETSQIDGPSLNNTYGFKV
SIQNLQEAKALHEIQNLTLISVELHARTRRDLEPDPEFDPICALFYCISSDTPLPDTEKT
ELTGVIVIDKDKTVFSQDIRYQTPLLIRSGITGLEVTYAADEKALFHEIANIIKRYDPDI
LLGYEIQMHSWGYLLQRAAALSIDLCRMISRVPDDKIENRFAAERDEYGSYTMSEINIVG
RITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYRWKMVDHY
VSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVT
PSVQQRSQMRAPQCVPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENL
GKYDEFKFGCTSLRVPPDLLYQVRHDITVSPNGVAFVKPSVRKGVLPRMLEEILKTRFMV
KQSMKAYKQDRALSRMLDARQLGLKLIANVTFGYTSANFSGRMPCIEVGDSIVHKARETL
ERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKF
EKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERSLKLLFET
RDISLIKQYVQRQCMKLLEGKASIQDFIFAKEYRGSFSYKPGACVPALELTRKMLTYDRR
SEPQVGERVPYVIIYGTPGVPLIQLVRRPVEVLQDPTLRLNATYYITKQILPPLARIFSL
IGIDVFSWYHELPRIHKATSSSRSEPEGRKGTISQYFTTLHCPVCDDLTQHGICSKCRSQ
PQHVAVILNQEIRELERQQEQLVKICKNCTGCFDRHIPCVSLNCPVLFKLSRVNRELSKA
PYLRQLLDQF
NT seq
9393 nt
NT seq
+upstream
nt +downstream
nt
atgttttcagtaaggatagtgactgcagactactacatggccagcccgctgcaggggctg
gatacctgccaatcccccctcacccaggcccctgtcaagaaggtgccggtggtgcgagtc
ttcggagcgaccccggcaggtcagaagacatgtcttcatctacatggcatctttccttac
ctctatgtgccatacgatggttatggacagcagccagaaagctatctttctcagatggca
ttcagtatcgacagagcacttaatgtggctttaggcaatccatcttccactgctcagcat
gtgttcaaagtgtcattagtatcaggaatgcctttttatggttatcatgagaaggaaaga
cactttatgaagatctatctttacaatcctacaatggtgaaaaggatatgtgaacttttg
caaagcggagccataatgaataaattttaccagcctcatgaagcgcatattccctacctc
ctacagctcttcattgactacaatctttatggcatgaatttaataaatctggctgctgtc
aagttccgaaaagcaagaaggaaaagtaatacattgcatgcaactggatcctgcaagaat
catttatcaggaaattctcttgctgatactttatttcggtgggaacaagatgaaatacca
agctctttaatattggaaggtgttgaaccacagagtacatgtgaattagaagtggatgct
gtagctgctgatatcttaaatcgtctggacattgaagctcaaattggtggaaaccctggt
ctacaggccatatgggaagatgaaaagcaacggcgaagaaacagaaatgaaacttctcaa
atgagccaacctgagtcacaagatcacaggtttgtgccagcaacagaaagtgaaaaaaaa
tttcagaagagacttcaggaaattctcaaacagaatgatttctctgtaacattatcagga
tctgtggactacagcgatggatcccaggagttctctgctgagttaacattgcactctgag
gttctgtctcctgaaatgcttcagtgtacaccagccaatatggtagaagttcacaaagac
aaagagtcaagcaaaggtcacactagacacaaagtggaagaagctcttattaatgaagaa
gcaattttgaaccttatggaaaatagtcagacttttcagcctttgacccaaagactgagt
gagtcacctgttttcatggacagtagtcctgatgaggctctggtacatcttcttgctggt
ttggaaagtgatggatatcggggggaaagaaataggatgccatcaccatgtcgctccttt
ggaaataataaatatccacaaaatagtgatgatgaagaaaatgaaccacagattgaaaaa
gaggaaatggagcttagtttggtgatgtcccagagatgggacagcaatattgaagaacat
tgtgccaaaaagagatcactgtgcagaaatacccacagaagttcaactgaagatgatgac
tcatcttcaggagaagaaatggaatggagtgataacagtttgcttctagccagtctttct
atacctcagttagatggaactgcagatgaaaatagtgacaatccattgaacaatgaaaat
tctagaacccactcttctgtaattgcaacaagcaagctttcagttaaaccctccatcttt
cacaaagatgctgctacattagaaccctcatcttctgctaagattacctttcagtgtaaa
cacacaagtgccctttcttcccatgttttgaacaaggaagatttaattgaagacctttca
cagacaaacaaaaatacagaaaaaggtctagataactcagtcacttcttttacaaacgaa
agcacttattctatgaaataccctggatctttaagcagtactgttcattcagaaaattct
cataaagagaatagtaagaaagagatcctcccagtatcttcctgtgaaagtagtattttt
gattatgaagaagatattccatctgttacaagacaagtaccaagtagaaaatatacaaac
attagaaaaatcgaaaaggattccccttttatacatatgcaccgtcaccctaacgagaat
acattgggcaaaaattctttcaacttttctgacttaaatcattcaaaaaataaagtatcc
tctgaaggaaatgaaaaaggaaacagcacagctctgagtagtttattcccttcatcattt
actgaaaattgtgaattactgtcatgctcaggggagaatagaactatggtgcattctctt
aatagcactgctgatgaaagtggactaaataaacttaaaattaggtatgaagaatttcaa
gaacataaaacagaaaagccaagcctcagccagcaagcagcacactatatgttttttccc
agtgttgttctttctaactgtcttactagaccacagaaactatctcctgtcacatataaa
ttacaacctggcaataaaccatcccggttaaaattgaataaaaggaaacttgcaggtcat
caggagacttctaccaaaagtagtgagactggatccacaaaagataattttatacaaaat
aatccttgtaatagtaatcctgagaaggataatgcattggctagtgatttaactaaaacc
actcgtggagcttttgaaaataaaacacccacagatggttttatagactgtcactttgga
gatggaacgttagaaactgagcagtcctttggactatatggaaataaatacacacttaga
gccaaacgcaaggtaaattatgagactgaagacagtgagtcaagttttgtaactcacaac
tcaaaaattagtctacctcatcccatggaaattggtgaaagtttagatggaactctcaaa
tcccgaaaacgaagaaaaatgtctaaaaagctgccccctgtcatcataaagtatattatt
attaatagatttagagggagaaaaaatatgcttgtgaagctaggaaaaatagactctaaa
gaaaaacaagtaatattaacagaagaaaaaatggaactatataaaaagcttgcacctttg
aaggacttttggccaaaagttcccgactcccctgcaaccaaatatcccatttatccacta
acaccaaagaaaagtcacagaagaaagtcaaaacataaatctgctaagaaaaaaactggt
aaacaacaaaggacaaataatgaaaatattaaaagaactttgtctttcaggaaaaaacgg
tcacatgctattctttctcctccctcaccatcttacaatgctgaaaccgaagattgtgac
ctgaattatagtgatgttatgtctaaactaggttttctttctgagagaagcacaagtccc
ataaattcttctccacctcgctgctggtctcccacagatccaagagctgaagaaatcatg
gctgctgcagaaaaagaggcaatgctttttaagggtcctaatgtatataagaagactgtt
aattctcgtataggaaaaactagtcgcgcaagagcacagattaagaaatcaaaagcaaag
cttgctaatccctctatagttactaagaaaaggaacaaacgaaatcagacaaataaacta
gtagatgatggaaaaaagaaaccaagagcaaaacaaaaaacaaatgagaaaggtacatcg
agaaagcatacaacacttaaggatgaaaaaataaaatctcagtctggtgctgaggttaag
tttgtactgaaacaccagaatgtgtctgaatttgcaagtagttctggaggctctcaacta
ctttttaaacagaaagatatgccactaatgggctctgctgtagatcatcccctttctgct
tccctacccactggaattaatgcacaacagaagttatctggctgcttttcttctttctta
gaaagcaagaagtctgtagatttgcagacattccccagttcacgagatgatttgcatcca
tcagttgtttgtaattctataggacctggagtctcaaaaattaatgttcaaaggcctcat
aatcaaagtgctatgtttactctaaaggaatcaacgttaattcaaaaaaatatatttgac
ctttccaatcatttatctcaggtagcacagaatacacagatatcttctggtatgtcctca
aagatagaagataatgcaaataatatacaaagaaactatttgtcatcaatcggaaagtta
agtgaatatcgcaattccctagaatcaaagctggaccaagcatatacccctaattttttg
cattgcaaagacagtcagcagcagattgtgtgcatagcggaacagtcaaagcacagtgaa
acttgttctccgggaaatacagcttcagaggaaagccaaatgcctaataattgctttgta
acttccttgagaagtccaatcaaacaaatagcatgggagcaaaagcaaaggggctttatt
ttagatatgtcaaattttaaacctgaaagagtaaaaccgaggtcgttatcagaagcaatt
tcacaaaccaaagcactttctcagtgtaaaaatcgaaatgtgtcaacaccttcagcattt
ggtgaaggacagtctggactggcagttctaaaagaattgttacaaaaaagacagcagaaa
gcacaaaatgcaaatactacacaagacccattatccaataaacatcaaccaaataaaaat
atttctggttcccttgagcataacaaagcaaataaacggacacgatcggtaacgtcccca
agaaaacctcgaactcccagaagtacaaaacaaaaagaaaaaatccccaaacttctcaaa
gtagactctttaaatttacaaaactctagccagttggataactctgtatcagatgatagt
cccatctttttttcagatccaggctttgaaagttgttactcacttgaagatagtttatct
cctgaacataattataattttgatattaacacaataggtcagactggattttgtagcttt
tattctggaagtcagtttgtcccagctgatcagaatttgcctcagaagttcctaagtgat
gctgttcaggatctttttccaggacaagctatagaaaaaaatgagtttttaagtcatgac
aaccagaaatgtgatgaagacaagcatcataccacagactcagcctcatggattagatct
ggtactttaagtcctgaaatttttgagaagtcaaccatagatagcaatgagaatcgtcgc
cacaaccagtggaaaaatagctttcatcctctaacaactcggtctaactcaataatggat
tctttctgtgttcagcaggcagaagactgtctaagtgaaaaatctagattgaataggagt
tcagtaagcaaagaagtgtttcttagcctcccacagccaaacaattcagactggattcaa
ggtcacaccagaaaagaaatgggacagtctcttgactcagccaatacctcttttactgca
atactctcctcccctgatggtgaacttgtagacgtggcctgtgaagatttagaactgtat
gtttcaagaaacaatgatatgttgacaccaactcctgatagttcaccaagatctactagc
tctccttcacaatctaaaaatggcagcttcacccctcgaactgctaacattctgaaacca
cttatgtcccccccaagtagggaagaaattatggcaactttgttggatcatgacctgtct
gagactatttaccaggaaccattttgcagtaatccttctgatgtaccagaaaagcccagg
gagattggtggacggctcctcatggtagaaactcgacttgcaaatgatctggctgagttt
gagggagacttttccttggaaggacttcgtctttggaaaacagcattctcagcaatgact
cagaatccaaggccagggtcaccccttcgcagtggccaaggagttgtcaataaagggtca
agtaatagccctaagatggttgaagataaaaaaattgtgattatgccttgcaaatgtgcc
ccaagtcgacaactggttcaagtgtggcttcaagccaaagaagaatacgaacgttccaag
aaactgcctaaaaccaagccaactggagttgtaaaatctgctgagaactttagctcttca
gttaacccagatgacaaacctgtagtgcctccaaaaatggatgtaagtccatgtatactc
cccactacagcacataccaaggaggatgttgataattctcagattgctttacaagcacca
accacgggatgtagtcaaactgcaagtgaaagtcagatgctgccaccagttgcctctgca
agtgatcccgaaaaagatgaagatgatgatgataactattacattagttatagctcccct
gattctccagtaattcccccttggcaacaaccaatatccccagattccaaagcattaaat
ggagatgatagaccctcatcaccagtagaggagctgccttcattggcttttgagaacttc
ttaaagccaataaaagatggtatacaaaaaagcccctgcagtgagcctcaagagcctcta
gtgatatctccaattaatactagggcaagaactgggaaatgtgaatcactttgctttcat
agtacaccaatcatacagagaaaacttctggaaaggcttcctgaagcacctggccttagc
ccattatcaacagaaccaaaaacacagaagttgagtaataagaaaggaagtaatactgac
actcttagaagagtactgttaacacaagcaaagaatcaatttgcagcagtaaatacccca
cagaaagaaacttctcagattgatggaccatctttaaacaatacttacggtttcaaagtc
agcatacaaaacttacaggaggcaaaagctttacatgagatacaaaatcttaccctaatc
agtgtggagttgcatgctcgaactagacgagacttagaaccggatcctgaatttgaccca
atctgtgctctgttctactgcatctcatctgacactccactgccagatacagaaaaaaca
gaactcacaggtgtaatagtgattgataaagacaagacagttttcagtcaagatatcaga
tatcagactccattacttattagatctggaattacaggactcgaagtcacctatgctgct
gatgagaaggcactttttcatgaaattgcaaatataataaagaggtatgatcctgatatt
ctgctaggatatgagattcagatgcattcctggggttacctcttacaaagggctgccgct
ttaagtattgacttatgtcggatgatctctcgggtgccagatgacaaaattgagaacaga
tttgcagctgaaagagatgagtatggatcatatacaatgagtgagataaatattgttggc
cgaattacactaaatctttggagaatcatgagaaatgaggtggctctaactaactacacc
tttgaaaatgtgagctttcatgttcttcatcagcgttttcccctctttacctttcgagtc
ttgtcagactggtttgataacaagacagatctatacagatggaaaatggttgatcattat
gttagccgtgtccgtggaaatctccaaatgttagaacagctggacctgattgggaaaacc
agtgagatggctagactttttggcattcagtttttacatgtactgacaaggggttcacag
taccgtgtggaatcaatgatgttgcgtattgctaaaccaatgaactatattcctgtgaca
cctagtgttcagcaaagatcccagatgagagccccacagtgtgttcctctaattatggag
cctgaatcccgcttctatagcaactctgttctcgttttggatttccaatcactttatcct
tctattgtgattgcatataactactgcttttccacctgccttggccatgtggagaacttg
ggaaagtatgatgagttcaaatttggctgtacctctctgagagtacctccagatttactt
taccaagttaggcatgatatcacagtgtcccccaatggagtagcttttgtcaagccttca
gtaagaaaaggtgtactaccaagaatgcttgaagaaattttgaagactagatttatggtg
aagcagtcaatgaaggcttacaagcaagacagagccctgtcacgaatgcttgatgcgcgt
cagttgggacttaagctgatagcaaatgtcacatttggctatacatctgctaatttttct
gggagaatgccatgcattgaggttggcgatagtattgttcacaaagccagagagaccttg
gaacgagctattaaactggtgaatgataccaagaaatggggggctagggttgtatatggc
gatactgacagtatgtttgtgctactgaaaggagccactaaggagcagtcttttaagatt
ggtcaggaaattgccgaagctgtaactgctaccaatcctaaaccagtgaaattgaagttt
gaaaaggtatatttgccctgtgttttacaaacaaaaaagaggtatgtgggttacatgtat
gaaacactggatcagaaggacccagtatttgatgcaaaaggaatagaaacagtcagaaga
gattcctgccctgctgtttctaagatacttgagcgttctctaaagctgctatttgaaacg
agagatataagtctaattaaacagtatgttcagcgacaatgtatgaagcttctggaagga
aaggccagcatacaagactttatctttgccaaggaatacagaggaagtttttcttataaa
ccaggagcttgtgtgccagcccttgaacttacaaggaaaatgctgacttatgaccggcgc
tctgagcctcaggttggggagcgagtgccatacgtcatcatttatgggacccccggagta
ccacttatccagcttgtaaggcgcccagtggaagtcctgcaggacccaactctgagactg
aatgctacttactatattaccaagcaaatccttccacccttggcaagaatcttctcactt
attggtattgatgtcttcagctggtatcatgaattaccaaggatccataaagctaccagc
tcctcgcgaagtgaacctgaagggcggaaaggcactatttcacaatattttactacctta
cactgtcctgtgtgtgatgacctaactcagcatggcatctgtagtaaatgtcggagccaa
cctcagcatgttgcagtcatcctcaaccaagaaatccgggagttggaacgtcaacaggag
caacttgtaaagatatgcaagaactgtacaggttgctttgatcgacacatcccatgtgtt
tctctgaactgcccagtacttttcaaactctcccgagtaaatagagaattgtccaaggca
ccatatctccggcagttattagaccagttttaa
DBGET
integrated database retrieval system
