Homo sapiens (human): 60495
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Entry
60495 CDS
T01001
Symbol
HPSE2, HPA2, HPR2, UFS, UFS1
Name
(RefSeq) heparanase 2 (inactive)
KO
K07965
heparanase 2 [EC:3.2.1.-]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00531
Glycosaminoglycan degradation
hsa01100
Metabolic pathways
hsa05205
Proteoglycans in cancer
Module
hsa_M00078
Heparan sulfate degradation
Disease
H00753
Urofacial syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00531 Glycosaminoglycan degradation
60495 (HPSE2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
60495 (HPSE2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
00536 Glycosaminoglycan binding proteins [BR:
hsa00536
]
60495 (HPSE2)
Glycosaminoglycan binding proteins [BR:
hsa00536
]
Heparan sulfate / Heparin
Enzymes
60495 (HPSE2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Glyco_hydro_79n
Motif
Other DBs
NCBI-GeneID:
60495
NCBI-ProteinID:
NP_068600
OMIM:
613469
HGNC:
18374
Ensembl:
ENSG00000172987
UniProt:
Q8WWQ2
Q2M1H9
LinkDB
All DBs
Position
10:complement(98457077..99315951)
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AA seq
592 aa
AA seq
DB search
MRVLCAFPEAMPSSNSRPPACLAPGALYLALLLHLSLSSQAGDRRPLPVDRAAGLKEKTL
ILLDVSTKNPVRTVNENFLSLQLDPSIIHDGWLDFLSSKRLVTLARGLSPAFLRFGGKRT
DFLQFQNLRNPAKSRGGPGPDYYLKNYEDDIVRSDVALDKQKGCKIAQHPDVMLELQREK
AAQMHLVLLKEQFSNTYSNLILTARSLDKLYNFADCSGLHLIFALNALRRNPNNSWNSSS
ALSLLKYSASKKYNISWELGNEPNNYRTMHGRAVNGSQLGKDYIQLKSLLQPIRIYSRAS
LYGPNIGRPRKNVIALLDGFMKVAGSTVDAVTWQHCYIDGRVVKVMDFLKTRLLDTLSDQ
IRKIQKVVNTYTPGKKIWLEGVVTTSAGGTNNLSDSYAAGFLWLNTLGMLANQGIDVVIR
HSFFDHGYNHLVDQNFNPLPDYWLSLLYKRLIGPKVLAVHVAGLQRKPRPGRVIRDKLRI
YAHCTNHHNHNYVRGSITLFIINLHRSRKKIKLAGTLRDKLVHQYLLQPYGQEGLKSKSV
QLNGQPLVMVDDGTLPELKPRPLRAGRTLVIPPVTMGFYVVKNVNALACRYR
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atgagggtgctttgtgccttccctgaagccatgccctccagcaactcccgcccccccgcg
tgcctagccccgggggctctctacttggctctgttgctccatctctccctttcctcccag
gctggagacaggagacccttgcctgtagacagagctgcaggtttgaaggaaaagaccctg
attctacttgatgtgagcaccaagaacccagtcaggacagtcaatgagaacttcctctct
ctgcagctggatccgtccatcattcatgatggctggctcgatttcctaagctccaagcgc
ttggtgaccctggcccggggactttcgcccgcctttctgcgcttcgggggcaaaaggacc
gacttcctgcagttccagaacctgaggaacccggcgaaaagccgcgggggcccgggcccg
gattactatctcaaaaactatgaggatgacattgttcgaagtgatgttgccttagataaa
cagaaaggctgcaagattgcccagcaccctgatgttatgctggagctccaaagggagaag
gcagctcagatgcatctggttcttctaaaggagcaattctccaatacttacagtaatctc
atattaacagccaggtctctagacaaactttataactttgctgattgctctggactccac
ctgatatttgctctaaatgcactgcgtcgtaatcccaataactcctggaacagttctagt
gccctgagtctgttgaagtacagcgccagcaaaaagtacaacatttcttgggaactgggt
aatgagccaaataactatcggaccatgcatggccgggcagtaaatggcagccagttggga
aaggattacatccagctgaagagcctgttgcagcccatccggatttattccagagccagc
ttatatggccctaatattgggcggccgaggaagaatgtcatcgccctcctagatggattc
atgaaggtggcaggaagtacagtagatgcagttacctggcaacattgctacattgatggc
cgggtggtcaaggtgatggacttcctgaaaactcgcctgttagacacactctctgaccag
attaggaaaattcagaaagtggttaatacatacactccaggaaagaagatttggcttgaa
ggtgtggtgaccacctcagctggaggcacaaacaatctatccgattcctatgctgcagga
ttcttatggttgaacactttaggaatgctggccaatcagggcattgatgtcgtgatacgg
cactcattttttgaccatggatacaatcacctcgtggaccagaattttaacccattacca
gactactggctctctctcctctacaagcgcctgatcggccccaaagtcttggctgtgcat
gtggctgggctccagcggaagccacggcctggccgagtgatccgggacaaactaaggatt
tatgctcactgcacaaaccaccacaaccacaactacgttcgtgggtccattacacttttt
atcatcaacttgcatcgatcaagaaagaaaatcaagctggctgggactctcagagacaag
ctggttcaccagtacctgctgcagccctatgggcaggagggcctaaagtccaagtcagtg
caactgaatggccagcccttagtgatggtggacgacgggaccctcccagaattgaagccc
cgcccccttcgggccggccggacattggtcatccctccagtcaccatgggcttttatgtg
gtcaagaatgtcaatgctttggcctgccgctaccgataa
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