Homo sapiens (human): 6272 Help Entry 6272              CDS       T01001                                  Symbol SORT1, Gp95, LDLCQ6, NT3, NTR3 Name (RefSeq) sortilin 1   KO K12388   sortilin Organism hsa  Homo sapiens (human) Pathway hsa04142   Lysosome hsa04722   Neurotrophin signaling pathway hsa04979   Cholesterol metabolism Drug target Latozinemab:  D12427 Sudotaxel zendusortide:  D12580 Zendusortide:  D12581 Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09141 Transport and catabolism    04142 Lysosome     6272 (SORT1)  09150 Organismal Systems   09154 Digestive system    04979 Cholesterol metabolism     6272 (SORT1)   09156 Nervous system    04722 Neurotrophin signaling pathway     6272 (SORT1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Sortilin-Vps10 Sortilin_C BNR_6 BNR Motif Other DBs NCBI-GeneID:  6272 NCBI-ProteinID:  NP_002950 OMIM:  602458 HGNC:  11186 Ensembl:  ENSG00000134243 UniProt:  Q99523 Structure PDB LinkDB All DBs Position 1:complement(109309575..109397918) Genome browser AA seq 831 aa AA seqDB search MERPWGAADGLSRWPHGLGLLLLLQLLPPSTLSQDRLDAPPPPAAPLPRWSGPIGVSWGL RAAAAGGAFPRGGRWRRSAPGEDEECGRVRDFVAKLANNTHQHVFDDLRGSVSLSWVGDS TGVILVLTTFHVPLVIMTFGQSKLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSG KVVLTAEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLW VSKNFGGKWEEIHKAVCLAKWGSDNTIFFTTYANGSCKADLGALELWRTSDLGKSFKTIG VKIYSFGLGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDM VFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLS EDNSIQTMITFDQGGRWTHLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPMAPLS EPNAVGIVIAHGSVGDAISVMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHS SRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLASEPGARSMNISIWGFTESFLTSQWVSY TIDFKDILERNCEEKDYTIWLAHSTDPEDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVT KQPSICLCSLEDFLCDFGYYRPENDSKCVEQPELKGHDLEFCLYGREEHLTTNGYRKIPG DKCQGGVNPVREVKDLKKKCTSNFLSPEKQNSKSNSVPIILAIVGLMLVTVVAGVLIVKK YVCGGRFLVHRYSVLQQHAEANGVDGVDALDTASHTNKSGYHDDSDEDLLE NT seq 2496 nt NT seq  +upstreamnt  +downstreamnt atggagcggccctggggagctgcggacggcctctcgcgctggccccatggcctcggcctc ctcctcctcctgcagctgctgccgccgtcgaccctcagccaggaccggctggacgcgccg ccgccgcccgctgcgccgctgccgcgctggtctggccccatcggggtgagctgggggctg cgggcggccgcagccgggggcgcgtttccccgcggcggccgttggcgtcgcagcgcgccg ggcgaggacgaggagtgcggccgggtccgggacttcgtcgccaagctggccaacaacacg caccagcatgtgtttgatgatctcagaggctcagtatccttgtcctgggttggagatagc actggggtcattctagtcttgactaccttccatgtaccactggtaattatgacttttgga cagtccaagctatatcgaagtgaggattatgggaagaactttaaggatattacagatctc atcaataacacctttattcggactgaatttggcatggctattggtcctgagaactctgga aaggtggtgttaacagcagaggtgtctggaggaagtcgtggaggaagaatctttagatca tcagattttgcgaagaattttgtgcaaacagatctcccttttcatcctctcactcagatg atgtatagccctcagaattctgattatcttttagctctcagcactgaaaatggcctgtgg gtgtccaagaattttgggggaaaatgggaagaaatccacaaagcagtatgtttggccaaa tggggatcagacaacaccatcttctttacaacctatgcaaatggctcctgcaaagctgac cttggggctctggaattatggagaacttcagacttgggaaaaagcttcaaaactattggt gtgaaaatctactcatttggtcttgggggacgtttcctttttgcctctgtgatggctgat aaggatacaacaagaaggatccacgtttcaacagatcaaggggacacatggagcatggcc cagctcccctccgtgggacaggaacagttctattctattctggcagcaaatgatgacatg gtattcatgcatgtagatgaacctggagacactgggtttggcacaatctttacctcagat gatcgaggcattgtctattccaagtctttggaccgacatctctacactaccacaggcgga gagacggactttaccaacgtgacctccctccgcggcgtctacataacaagcgtgctctcc gaagataattctatccagaccatgatcacttttgaccaaggaggaaggtggacgcacctg aggaagcctgaaaacagtgaatgtgatgctacagcaaaaaacaagaatgagtgcagcctt catattcatgcttcctacagcatctcccagaaactgaatgttccaatggccccactctca gagccgaatgccgtaggcattgtcattgctcatggtagcgtgggggatgccatctcagtg atggttccagatgtgtacatctcagatgatgggggttactcctggacaaagatgctggaa ggaccccactattacaccatcctggattctggaggcatcattgtggccattgagcacagc agccgtcctatcaatgtgattaagttctccacagacgaaggtcaatgctggcaaacctac acgttcaccagggaccccatctatttcactggcctagcttcagaacctggagctaggtcc atgaatatcagcatttggggcttcacagaatctttcctgaccagccagtgggtctcctac accattgattttaaagatatccttgaaaggaactgtgaagagaaggactataccatatgg ctggcacactccacagaccctgaagattatgaagatggctgcattttgggctacaaagaa cagtttctgcggctacgcaagtcatccgtgtgtcagaatggtcgagactatgttgtgacc aagcagccctccatctgcctctgttccctggaggactttctctgtgattttggctactac cgtccagaaaatgactccaagtgtgtggaacagccagaactgaagggccacgacctggag ttttgtctgtacggaagagaagaacacctaacaacaaatgggtaccggaaaattccaggg gacaaatgccagggtggggtaaatccagttcgagaagtaaaagacttgaaaaagaaatgc acaagcaactttttgagtccggaaaaacagaattccaagtcaaattctgttccaattatc ctggccatcgtgggattgatgctggtcacagtcgtagcaggagtgctcattgtgaagaaa tatgtctgtgggggaaggttcctggtgcatcgatactctgtgctgcagcagcatgcagag gccaatggtgtggatggtgtggatgctttggacacagcctcccacactaataaaagtggt tatcatgatgactcagatgaggacctcttggaatag

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