Homo sapiens (human): 6347
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Entry
6347 CDS
T01001
Symbol
CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF
Name
(RefSeq) C-C motif chemokine ligand 2
KO
K14624
C-C motif chemokine 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04061
Viral protein interaction with cytokine and cytokine receptor
hsa04062
Chemokine signaling pathway
hsa04621
NOD-like receptor signaling pathway
hsa04657
IL-17 signaling pathway
hsa04668
TNF signaling pathway
hsa04933
AGE-RAGE signaling pathway in diabetic complications
hsa05135
Yersinia infection
hsa05142
Chagas disease
hsa05144
Malaria
hsa05163
Human cytomegalovirus infection
hsa05164
Influenza A
hsa05168
Herpes simplex virus 1 infection
hsa05171
Coronavirus disease - COVID-19
hsa05323
Rheumatoid arthritis
hsa05417
Lipid and atherosclerosis
hsa05418
Fluid shear stress and atherosclerosis
Network
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06167
Human cytomegalovirus (HCMV)
nt06168
Herpes simplex virus 1 (HSV-1)
nt06171
SARS coronavirus 2 (SARS-CoV-2)
nt06224
CXCR signaling (cancer)
nt06516
TNF signaling
nt06533
Chemokine signaling
Element
N00153
CCR/CXCR-GNB/G-PI3K-RAC signaling pathway
N00399
CCR2-GNB/G-PI3K-NFKB signaling pathway
N00406
HCMV US28 to GNA12/13-Rho signaling pathway
N00560
HSV gD to HVEM-NFKB signaling pathway
N01307
SARS-CoV-2 S to AngII-AT1R-NOX2 signaling pathway
N01746
CCR/CXCR-GNB/G-PI3K signaling pathway
N01770
CCR2-GNB/G-PI3K signaling pathway
Disease
H00342
Tuberculosis
H01563
HIV infection
H02563
Neural tube defects
Drug target
Bindarit:
D03116
Carlumab:
D09877
Emapticap pegol:
D12654
Pirfenidone:
D01583
<JP/US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04668 TNF signaling pathway
6347 (CCL2)
09133 Signaling molecules and interaction
04061 Viral protein interaction with cytokine and cytokine receptor
6347 (CCL2)
09150 Organismal Systems
09151 Immune system
04657 IL-17 signaling pathway
6347 (CCL2)
04062 Chemokine signaling pathway
6347 (CCL2)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
6347 (CCL2)
05164 Influenza A
6347 (CCL2)
05163 Human cytomegalovirus infection
6347 (CCL2)
09171 Infectious disease: bacterial
05135 Yersinia infection
6347 (CCL2)
09174 Infectious disease: parasitic
05144 Malaria
6347 (CCL2)
05142 Chagas disease
6347 (CCL2)
09163 Immune disease
05323 Rheumatoid arthritis
6347 (CCL2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
6347 (CCL2)
05418 Fluid shear stress and atherosclerosis
6347 (CCL2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
6347 (CCL2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
hsa04052
]
6347 (CCL2)
00536 Glycosaminoglycan binding proteins [BR:
hsa00536
]
6347 (CCL2)
Cytokines and neuropeptides [BR:
hsa04052
]
Cytokines
Chemokines
6347 (CCL2)
Glycosaminoglycan binding proteins [BR:
hsa00536
]
Heparan sulfate / Heparin
Chemokines
6347 (CCL2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
IL8
CXCL16
Motif
Other DBs
NCBI-GeneID:
6347
NCBI-ProteinID:
NP_002973
OMIM:
158105
HGNC:
10618
Ensembl:
ENSG00000108691
UniProt:
P13500
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:34255285..34257203
Genome browser
AA seq
99 aa
AA seq
DB search
MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCP
KEAVIFKTIVAKEICADPKQKWVQDSMDHLDKQTQTPKT
NT seq
300 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtctctgccgcccttctgtgcctgctgctcatagcagccaccttcattccccaa
gggctcgctcagccagatgcaatcaatgccccagtcacctgctgttataacttcaccaat
aggaagatctcagtgcagaggctcgcgagctatagaagaatcaccagcagcaagtgtccc
aaagaagctgtgatcttcaagaccattgtggccaaggagatctgtgctgaccccaagcag
aagtgggttcaggattccatggaccacctggacaagcaaacccaaactccgaagacttga
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