Homo sapiens (human): 652968
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Entry
652968 CDS
T01001
Symbol
CASTOR1, GATSL3
Name
(RefSeq) cytosolic arginine sensor for mTORC1 subunit 1
KO
K23080
cytosolic arginine sensor for mTORC1 subunit 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04150
mTOR signaling pathway
Drug target
Sapanisertib:
D11183
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04150 mTOR signaling pathway
652968 (CASTOR1)
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Gene cluster
GFIT
Motif
Pfam:
ACT_7
CASTOR1_ACT-like
Castor1_N
Motif
Other DBs
NCBI-GeneID:
652968
NCBI-ProteinID:
NP_001032755
OMIM:
617034
HGNC:
34423
Ensembl:
ENSG00000239282
UniProt:
Q8WTX7
Structure
PDB
PDBj
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Position
22:complement(30285117..30289505)
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AA seq
329 aa
AA seq
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MELHILEHRVRVLSVARPGLWLYTHPLIKLLFLPRRSRCKFFSLTETPEDYTLMVDEEGF
KELPPSEFLQVAEATWLVLNVSSHSGAAVQAAGVTKIARSVIAPLAEHHVSVLMLSTYQT
DFILVREQDLSVVIHTLAQEFDIYREVGGEPVPVTRDDSSNGFPRTQHGPSPTVHPIQSP
QNRFCVLTLDPETLPAIATTLIDVLFYSHSTPKEAASSSPEPSSITFFAFSLIEGYISIV
MDAETQKKFPSDLLLTSSSGELWRMVRIGGQPLGFDECGIVAQIAGPLAAADISAYYIST
FNFDHALVPEDGIGSVIEVLQRRQEGLAS
NT seq
990 nt
NT seq
+upstream
nt +downstream
nt
atggagctgcacatcctagaacaccgggtgcgggtgctgagcgtcgcccgtcccggtctc
tggctctacacccacccgctcatcaagctgctcttcctgccccgccgcagccggtgcaag
ttcttcagcctgacggagacccctgaggattacacgcttatggtggacgaggagggcttt
aaagagctgcccccatctgagttcctgcaagtagctgaggccacatggctggtgctgaac
gtgtcgtctcacagcggtgcggcagtgcaggctgctggggtcaccaagatcgcccgttcg
gtcatcgcgccactggccgagcaccacgtgtctgtgctgatgctgtccacttaccagacg
gacttcatcctggtgcgggagcaggacctgtccgtggtgatccacacgctggcccaggag
ttcgacatttaccgcgaggtgggcggagagcctgtgcctgtgacgagggatgattccagc
aatggctttccccgcactcagcatgggcccagccccacggtgcatcccatccagagccca
cagaaccgcttctgtgtcctcacactggaccctgagacgcttccagccatcgccaccacc
ctcatagatgtcctcttctactcgcacagcacccccaaggaggcagcctctagcagtcct
gaacccagctccatcacgttctttgccttctccctcatcgagggttatatctccattgtc
atggatgctgaaacacagaaaaagttccccagtgacctcctgctgaccagctcctcgggg
gagctgtggaggatggtgcgcatcggtggacagcccctgggctttgatgaatgtggcatc
gtggcacagattgcaggtcccctggctgccgctgacatctctgcctactacatcagcacc
ttcaacttcgaccacgccctggtgcccgaggacggtatcggcagcgtcatcgaggtcctc
cagcggcggcaggaaggcctggcttcctga
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