Homo sapiens (human): 6547
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Entry
6547 CDS
T01001
Symbol
SLC8A3, NCX3
Name
(RefSeq) solute carrier family 8 member A3
KO
K05849
solute carrier family 8 (sodium/calcium exchanger)
Organism
hsa
Homo sapiens (human)
Pathway
hsa04020
Calcium signaling pathway
hsa04022
cGMP-PKG signaling pathway
hsa04260
Cardiac muscle contraction
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04371
Apelin signaling pathway
hsa04740
Olfactory transduction
hsa04961
Endocrine and other factor-regulated calcium reabsorption
hsa04974
Protein digestion and absorption
hsa04978
Mineral absorption
hsa05410
Hypertrophic cardiomyopathy
hsa05412
Arrhythmogenic right ventricular cardiomyopathy
hsa05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
6547 (SLC8A3)
04020 Calcium signaling pathway
6547 (SLC8A3)
04022 cGMP-PKG signaling pathway
6547 (SLC8A3)
09150 Organismal Systems
09153 Circulatory system
04260 Cardiac muscle contraction
6547 (SLC8A3)
04261 Adrenergic signaling in cardiomyocytes
6547 (SLC8A3)
09154 Digestive system
04974 Protein digestion and absorption
6547 (SLC8A3)
04978 Mineral absorption
6547 (SLC8A3)
09155 Excretory system
04961 Endocrine and other factor-regulated calcium reabsorption
6547 (SLC8A3)
09157 Sensory system
04740 Olfactory transduction
6547 (SLC8A3)
09160 Human Diseases
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
6547 (SLC8A3)
05412 Arrhythmogenic right ventricular cardiomyopathy
6547 (SLC8A3)
05414 Dilated cardiomyopathy
6547 (SLC8A3)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
6547 (SLC8A3)
00536 Glycosaminoglycan binding proteins [BR:
hsa00536
]
6547 (SLC8A3)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC8: Na+/Ca2+ exchanger
6547 (SLC8A3)
Glycosaminoglycan binding proteins [BR:
hsa00536
]
Heparan sulfate / Heparin
Others
6547 (SLC8A3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Calx-beta
Na_Ca_ex_C
Na_Ca_ex
Motif
Other DBs
NCBI-GeneID:
6547
NCBI-ProteinID:
NP_892114
OMIM:
607991
HGNC:
11070
Ensembl:
ENSG00000100678
UniProt:
P57103
LinkDB
All DBs
Position
14:complement(70044215..70189405)
Genome browser
AA seq
927 aa
AA seq
DB search
MAWLRLQPLTSAFLHFGLVTFVLFLNGLRAEAGGSGDVPSTGQNNESCSGSSDCKEGVIL
PIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPNGE
TSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNMFI
IIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTLFF
FPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKGIEMDGKMMNSHFLDGN
LVPLEGKEVDESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQKSRAFYRIQATR
MMTGAGNILKKHAAEQAKKASSMSEVHTDEPEDFISKVFFDPCSYQCLENCGAVLLTVVR
KGGDMSKTMYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVGIIDDDIFEEDEHF
FVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAVLASPCVATVTILDDDHAGIFTFECDTIH
VSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGELEFKNDETVKTIRV
KIVDEEEYERQENFFIALGEPKWMERGISALLLSPDVTDRKLTMEEEEAKRIAEMGKPVL
GEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESG
EERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFG
CTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAW
SVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLA
TTWLFVSLWLLYILFATLEAYCYIKGF
NT seq
2784 nt
NT seq
+upstream
nt +downstream
nt
atggcgtggttaaggttgcagcctctcacctctgccttcctccattttgggctggttacc
tttgtgctcttcctgaatggtcttcgagcagaggctggtggctcaggggacgtgccaagc
acagggcagaacaatgagtcctgttcagggtcatcggactgcaaggagggtgtcatcctg
ccaatctggtacccggagaacccttcccttggggacaagattgccagggtcattgtctat
tttgtggccctgatatacatgttccttggggtgtccatcattgctgaccgcttcatggca
tctattgaagtcatcacctctcaagagagggaggtgacaattaagaaacccaatggagaa
accagcacaaccactattcgggtctggaatgaaactgtctccaacctgacccttatggcc
ctgggttcctctgctcctgagatactcctctctttaattgaggtgtgtggtcatgggttc
attgctggtgatctgggaccttctaccattgtagggagtgcagccttcaacatgttcatc
atcattggcatctgtgtctacgtgatcccagacggagagactcgcaagatcaagcatcta
cgagtcttcttcatcaccgctgcttggagtatctttgcctacatctggctctatatgatt
ctggcagtcttctcccctggtgtggtccaggtttgggaaggcctcctcactctcttcttc
tttccagtgtgtgtccttctggcctgggtggcagataaacgactgctcttctacaaatac
atgcacaaaaagtaccgcacagacaaacaccgaggaattatcatagagacagagggtgac
caccctaagggcattgagatggatgggaaaatgatgaattcccattttctagatgggaac
ctggtgcccctggaagggaaggaagtggatgagtcccgcagagagatgatccggattctc
aaggatctgaagcaaaaacacccagagaaggacttagatcagctggtggagatggccaat
tactatgctctttcccaccaacagaagagccgtgccttctaccgtatccaagccactcgt
atgatgactggtgcaggcaatatcctgaagaaacatgcagcagaacaagccaagaaggcc
tccagcatgagcgaggtgcacaccgatgagcctgaggactttatttccaaggtcttcttt
gacccatgttcttaccagtgcctggagaactgtggggctgtactcctgacagtggtgagg
aaagggggagacatgtcaaagaccatgtatgtggactacaaaacagaggatggttctgcc
aatgcaggggctgactatgagttcacagagggcacggtggttctgaagccaggagagacc
cagaaggagttctccgtgggcataattgatgacgacatttttgaggaggatgaacacttc
tttgtaaggttgagcaatgtccgcatagaggaggagcagccagaggaggggatgcctcca
gcaatattcaacagtcttcccttgcctcgggctgtcctagcctccccttgtgtggccaca
gttaccatcttggatgatgaccatgcaggcatcttcacttttgaatgtgatactattcat
gtcagtgagagtattggtgttatggaggtcaaggttctgcggacatcaggtgcccggggt
acagtcatcgtcccctttaggacagtagaagggacagccaagggtggcggtgaggacttt
gaagacacatatggggagttggaattcaagaatgatgaaactgtgaaaaccataagggtt
aaaatagtagatgaggaggaatacgaaaggcaagagaatttcttcattgcccttggtgaa
ccgaaatggatggaacgtggaatatcagcgctcctgttatctccagatgtgacagacagg
aagctgactatggaagaagaggaggccaagaggatagcagagatgggaaagccagtattg
ggtgaacaccccaaactagaagtcatcattgaagagtcctatgagttcaagactacggtg
gacaaactgatcaagaagacaaacctggccttggttgtggggacccattcctggagggac
cagttcatggaggccatcaccgtcagtgcagcaggggatgaggatgaggatgaatccggg
gaggagaggctgccctcctgctttgactacgtcatgcacttcctgactgtcttctggaag
gtgctgtttgcctgtgtgccccccacagagtactgccacggctgggcctgcttcgccgtc
tccatcctcatcattggcatgctcaccgccatcattggggacctggcctcgcacttcggc
tgcaccattggtctcaaagattcagtcacagctgttgttttcgtggcatttggcacctct
gtcccagatacgtttgccagcaaagctgctgccctccaggatgtatatgcagacgcctcc
attggcaacgtgacgggcagcaacgccgtcaatgtcttcctgggcatcggcctggcctgg
tccgtggccgccatctactgggctctgcagggacaggagttccacgtgtcggccggcaca
ctggccttctccgtcaccctcttcaccatctttgcatttgtctgcatcagcgtgctcttg
taccgaaggcggccgcacctgggaggggagcttggtggcccccgtggctgcaagctcgcc
acaacatggctctttgtgagcctgtggctcctctacatactctttgccacactagaggcc
tattgctacatcaaggggttctaa
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