Homo sapiens (human): 6688
Help
Entry
6688 CDS
T01001
Symbol
SPI1, AGM10, OF, PU.1, SFPI1, SPI-1, SPI-A
Name
(RefSeq) Spi-1 proto-oncogene
KO
K09438
transcription factor PU.1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04380
Osteoclast differentiation
hsa05166
Human T-cell leukemia virus 1 infection
hsa05200
Pathways in cancer
hsa05202
Transcriptional misregulation in cancer
hsa05221
Acute myeloid leukemia
Network
nt06240
Transcription (cancer)
nt06275
Acute myeloid leukemia
Element
N00112
AML1-ETO fusion to PU.1-mediated transcription
Disease
H00085
Agammaglobulinemias
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09158 Development and regeneration
04380 Osteoclast differentiation
6688 (SPI1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
6688 (SPI1)
05202 Transcriptional misregulation in cancer
6688 (SPI1)
09162 Cancer: specific types
05221 Acute myeloid leukemia
6688 (SPI1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
6688 (SPI1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hsa03000
]
6688 (SPI1)
Transcription factors [BR:
hsa03000
]
Eukaryotic type
Helix-turn-helix
Tryptophan clusters Ets-type
6688 (SPI1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ets
DUF6443
Motif
Other DBs
NCBI-GeneID:
6688
NCBI-ProteinID:
NP_003111
OMIM:
165170
HGNC:
11241
Ensembl:
ENSG00000066336
Pharos:
P17947
(Tbio)
UniProt:
P17947
Structure
PDB
LinkDB
All DBs
Position
11:complement(47354860..47378547)
Genome browser
AA seq
270 aa
AA seq
DB search
MLQACKMEGFPLVPPPSEDLVPYDTDLYQRQTHEYYPYLSSDGESHSDHYWDFHPHHVHS
EFESFAENNFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHPSLGHQVSYLPRMCLQ
YPSLSPAQPSSDEEEGERQSPPLEVSDGEADGLEPGPGLLPGETGSKKKIRLYQFLLDLL
RSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKTGE
VKKVKKKLTYQFSGEVLGRGGLAERRHPPH
NT seq
813 nt
NT seq
+upstream
nt +downstream
nt
atgttacaggcgtgcaaaatggaagggtttcccctcgtcccccctccatcagaagacctg
gtgccctatgacacggatctataccaacgccaaacgcacgagtattacccctatctcagc
agtgatggggagagccatagcgaccattactgggacttccacccccaccacgtgcacagc
gagttcgagagcttcgccgagaacaacttcacggagctccagagcgtgcagcccccgcag
ctgcagcagctctaccgccacatggagctggagcagatgcacgtcctcgatacccccatg
gtgccaccccatcccagtcttggccaccaggtctcctacctgccccggatgtgcctccag
tacccatccctgtccccagcccagcccagctcagatgaggaggagggcgagcggcagagc
cccccactggaggtgtctgacggcgaggcggatggcctggagcccgggcctgggctcctg
cctggggagacaggcagcaagaagaagatccgcctgtaccagttcctgttggacctgctc
cgcagcggcgacatgaaggacagcatctggtgggtggacaaggacaagggcaccttccag
ttctcgtccaagcacaaggaggcgctggcgcaccgctggggcatccagaagggcaaccgc
aagaagatgacctaccagaagatggcgcgcgcgctgcgcaactacggcaagacgggcgag
gtcaagaaggtgaagaagaagctcacctaccagttcagcggcgaagtgctgggccgcggg
ggcctggccgagcggcgccacccgccccactga
DBGET
integrated database retrieval system
