Homo sapiens (human): 731 Help Entry 731               CDS       T01001                                  Symbol C8A Name (RefSeq) complement C8 alpha chain   KO K03997   complement component 8 subunit alpha Organism hsa  Homo sapiens (human) Pathway hsa04610   Complement and coagulation cascades hsa04810   Regulation of actin cytoskeleton hsa05020   Prion disease hsa05146   Amoebiasis hsa05171   Coronavirus disease - COVID-19 hsa05322   Systemic lupus erythematosus Network nt06513  Complement cascade   Element N01490   Common pathway of complement cascade, MAC formation N01505   Regulation of complement cascade, MAC inhibition Disease H00103   Late complement pathway defects Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     731 (C8A)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     731 (C8A)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     731 (C8A)   09174 Infectious disease: parasitic    05146 Amoebiasis     731 (C8A)   09163 Immune disease    05322 Systemic lupus erythematosus     731 (C8A)   09164 Neurodegenerative disease    05020 Prion disease     731 (C8A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MACPF Ldl_recept_a TSP_1 TSP1_spondin Motif Other DBs NCBI-GeneID:  731 NCBI-ProteinID:  NP_000553 OMIM:  120950 HGNC:  1352 Ensembl:  ENSG00000157131 Pharos:  P07357(Tbio) UniProt:  P07357 Structure PDB LinkDB All DBs Position 1:56854797..56918223 Genome browser AA seq 584 aa AA seqDB search MFAVVFFILSLMTCQPGVTAQEKVNQRVRRAATPAAVTCQLSNWSEWTDCFPCQDKKYRH RSLLQPNKFGGTICSGDIWDQASCSSSTTCVRQAQCGQDFQCKETGRCLKRHLVCNGDQD CLDGSDEDDCEDVRAIDEDCSQYEPIPGSQKAALGYNILTQEDAQSVYDASYYGGQCETV YNGEWRELRYDSTCERLYYGDDEKYFRKPYNFLKYHFEALADTGISSEFYDNANDLLSKV KKDKSDSFGVTIGIGPAGSPLLVGVGVSHSQDTSFLNELNKYNEKKFIFTRIFTKVQTAH FKMRKDDIMLDEGMLQSLMELPDQYNYGMYAKFINDYGTHYITSGSMGGIYEYILVIDKA KMESLGITSRDITTCFGGSLGIQYEDKINVGGGLSGDHCKKFGGGKTERARKAMAVEDII SRVRGGSSGWSGGLAQNRSTITYRSWGRSLKYNPVVIDFEMQPIHEVLRHTSLGPLEAKR QNLRRALDQYLMEFNACRCGPCFNNGVPILEGTSCRCQCRLGSLGAACEQTQTEGAKADG SWSCWSSWSVCRAGIQERRRECDNPAPQNGGASCPGRKVQTQAC NT seq 1755 nt NT seq  +upstreamnt  +downstreamnt atgtttgctgttgttttcttcatcttgtctttgatgacttgtcagcctggggtaactgca caggagaaggtgaaccagagagtaagacgggcagctacacccgcagcagttacctgccag ctgagcaactggtcagagtggacagattgctttccgtgccaggacaaaaagtaccgacac cggagcctcttgcagccaaacaagtttgggggaaccatctgcagtggtgacatctgggat caagccagctgctccagttctacaacttgtgtaaggcaagcacagtgtggacaggatttc cagtgtaaggagacaggtcgctgcctgaaacgccaccttgtgtgtaatggagaccaggac tgccttgatggctctgatgaggacgactgtgaagatgtcagggccattgacgaagactgc agccagtatgaaccaattccaggatcacagaaggcagccttggggtacaatatcctgacc caggaagatgctcagagtgtgtacgatgccagttattatgggggccagtgtgagacggta tacaatggggaatggagggagcttcgatatgactccacctgtgaacgtctctactatgga gatgatgagaaatactttcggaaaccctacaactttctgaagtaccactttgaagccctg gcagatactggaatctcctcagagttttatgataatgcaaatgaccttctttccaaagtt aaaaaagacaagtctgactcatttggagtgaccatcggcataggcccagccggcagccct ttattggtgggtgtaggtgtatcccactcacaagacacttcattcttgaacgaattaaac aagtataatgagaagaaattcattttcacaagaatcttcacaaaggtgcagactgcacat tttaagatgaggaaggatgacattatgctggatgaaggaatgctgcagtcattaatggag cttccagatcagtacaattatggcatgtatgccaagttcatcaatgactatggcacccat tacatcacatctggatccatgggtggcatttatgaatatatcctggtgattgacaaagca aaaatggaatcccttggtattaccagcagagatatcacgacatgttttggaggctccttg ggcattcaatatgaagacaaaataaatgttggtggaggtttatcaggagaccattgtaaa aaatttggaggtggcaaaactgaaagggccaggaaggccatggctgtggaagacattatt tctcgggtgcgaggtggcagttctggctggagcggtggcttggcacagaacaggagcacc attacataccgttcctgggggaggtcattaaagtataatcctgttgttatcgattttgag atgcagcctatccacgaggtgctgcggcacacaagcctggggcctctggaggccaagcgc cagaacctgcgccgcgccttggaccagtatctgatggaattcaatgcctgccgatgtggg ccttgcttcaacaatggggtgcccatcctcgagggcaccagctgcaggtgccagtgccgc ctgggtagcttgggtgctgcctgtgagcaaacacagacagaaggagccaaagcagatggg agctggagttgctggagctcctggtctgtatgcagagcaggcatccaggaaaggagaaga gagtgtgacaatccagcacctcagaatggaggggcctcgtgtccagggcggaaagtacag acgcaggcttgctga

Homo sapiens (human): 732 Help Entry 732               CDS       T01001                                  Symbol C8B, C82 Name (RefSeq) complement C8 beta chain   KO K03998   complement component 8 subunit beta Organism hsa  Homo sapiens (human) Pathway hsa04610   Complement and coagulation cascades hsa04810   Regulation of actin cytoskeleton hsa05020   Prion disease hsa05146   Amoebiasis hsa05171   Coronavirus disease - COVID-19 hsa05322   Systemic lupus erythematosus Network nt06513  Complement cascade   Element N01490   Common pathway of complement cascade, MAC formation N01505   Regulation of complement cascade, MAC inhibition Disease H00103   Late complement pathway defects Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     732 (C8B)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     732 (C8B)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     732 (C8B)   09174 Infectious disease: parasitic    05146 Amoebiasis     732 (C8B)   09163 Immune disease    05322 Systemic lupus erythematosus     732 (C8B)   09164 Neurodegenerative disease    05020 Prion disease     732 (C8B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  MACPF Ldl_recept_a TSP1_spondin TSP_1 Motif Other DBs NCBI-GeneID:  732 NCBI-ProteinID:  NP_000057 OMIM:  120960 HGNC:  1353 Ensembl:  ENSG00000021852 Pharos:  P07358(Tbio) UniProt:  P07358 Structure PDB LinkDB All DBs Position 1:complement(56929207..56966015) Genome browser AA seq 591 aa AA seqDB search MKNSRTWAWRAPVELFLLCAALGCLSLPGSRGERPHSFGSNAVNKSFAKSRQMRSVDVTL MPIDCELSSWSSWTTCDPCQKKRYRYAYLLQPSQFHGEPCNFSDKEVEDCVTNRPCGSQV RCEGFVCAQTGRCVNRRLLCNGDNDCGDQSDEANCRRIYKKCQHEMDQYWGIGSLASGIN LFTNSFEGPVLDHRYYAGGCSPHYILNTRFRKPYNVESYTPQTQGKYEFILKEYESYSDF ERNVTEKMASKSGFSFGFKIPGIFELGISSQSDRGKHYIRRTKRFSHTKSVFLHARSDLE VAHYKLKPRSLMLHYEFLQRVKRLPLEYSYGEYRDLFRDFGTHYITEAVLGGIYEYTLVM NKEAMERGDYTLNNVHACAKNDFKIGGAIEEVYVSLGVSVGKCRGILNEIKDRNKRDTMV EDLVVLVRGGASEHITTLAYQELPTADLMQEWGDAVQYNPAIIKVKVEPLYELVTATDFA YSSTVRQNMKQALEEFQKEVSSCHCAPCQGNGVPVLKGSRCDCICPVGSQGLACEVSYRK NTPIDGKWNCWSNWSSCSGRRKTRQRQCNNPPPQNGGSPCSGPASETLDCS NT seq 1776 nt NT seq  +upstreamnt  +downstreamnt atgaagaattccaggacatgggcttggagggcgccggtggagctatttcttctctgtgct gccctgggctgtctcagtttgcctggctccagaggtgaaaggccacattcctttgggtca aatgcagtcaacaagagctttgctaagagcagacagatgcggagtgtggatgttaccctg atgcccattgattgtgagctgtctagttggtcctcttggaccacatgtgacccctgtcag aagaaaaggtacaggtatgcctacttgctccagccctctcagttccatggggaaccgtgc aacttctctgacaaggaagtcgaagactgtgttaccaacagaccatgcggaagtcaagtg cgatgtgaaggctttgtgtgtgcacagacaggaaggtgtgtaaaccgcagacttctttgc aatggggacaatgactgtggagaccagtcagatgaagcaaactgtagaaggatttataaa aaatgtcagcatgaaatggaccaatactggggaattggcagtctggccagtgggataaat ttgttcacaaacagttttgagggcccagttcttgatcacaggtattatgcaggtggatgc tccccgcattacatcctgaacacgaggtttaggaagccctacaatgtggaaagctacacg ccacagacccaaggcaaatacgaattcatattaaaagagtatgaatcatactcagatttt gaacgcaatgtcacagagaaaatggcaagcaagtctggtttcagttttggttttaaaata cctggaatatttgaacttggcatcagtagtcaaagtgatcgaggcaaacactatattagg agaaccaaacgattctctcatactaaaagcgtatttctgcatgcacgctctgaccttgaa gtagcacattacaagctgaaacccagaagcctcatgctccattacgagttccttcagaga gttaagcggctgcccctggagtacagctacggggaatacagagatctcttccgtgatttt gggacccactacatcacagaggctgtgcttgggggcatttatgaatacaccctcgttatg aacaaagaggccatggagagaggagattatactcttaacaacgtccatgcctgtgccaaa aatgattttaaaattggtggtgccattgaagaggtctacgtcagtctgggtgtgtctgta ggcaaatgcagaggtattctgaatgaaataaaagacagaaacaagagggacaccatggtg gaggacttggtggtcctggtacgaggaggggcaagtgagcacatcaccaccctggcatac caggagctgccgacggcggacctgatgcaggagtggggagacgctgtgcagtacaaccca gccatcatcaaagttaaggtggagcctctgtatgaactagtgacagccacagattttgcc tattccagcacagtgaggcagaacatgaagcaggcactggaggagttccagaaggaagtt agttcctgccactgtgctccctgccaaggaaatggagtccctgtcctgaaaggatcacgc tgtgactgcatctgtcctgttggatcccaaggcctagcctgtgaggtctcctatcggaag aatacccccattgatgggaagtggaattgctggtcaaattggtcttcatgctctggaaga cgtaagacaagacaaaggcagtgtaacaatccacctcctcaaaatgggggtagcccctgt tcaggccctgcttcagaaacacttgactgctcctag

Homo sapiens (human): 733 Help Entry 733               CDS       T01001                                  Symbol C8G, C8C Name (RefSeq) complement C8 gamma chain   KO K03999   complement component 8 subunit gamma Organism hsa  Homo sapiens (human) Pathway hsa04610   Complement and coagulation cascades hsa04810   Regulation of actin cytoskeleton hsa05020   Prion disease hsa05146   Amoebiasis hsa05171   Coronavirus disease - COVID-19 hsa05322   Systemic lupus erythematosus Network nt06513  Complement cascade   Element N01490   Common pathway of complement cascade, MAC formation N01505   Regulation of complement cascade, MAC inhibition Disease H00103   Late complement pathway defects Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09142 Cell motility    04810 Regulation of actin cytoskeleton     733 (C8G)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     733 (C8G)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     733 (C8G)   09174 Infectious disease: parasitic    05146 Amoebiasis     733 (C8G)   09163 Immune disease    05322 Systemic lupus erythematosus     733 (C8G)   09164 Neurodegenerative disease    05020 Prion disease     733 (C8G) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Lipocalin Motif Other DBs NCBI-GeneID:  733 NCBI-ProteinID:  NP_000597 OMIM:  120930 HGNC:  1354 Ensembl:  ENSG00000176919 Pharos:  P07360(Tbio) UniProt:  P07360 Structure PDB LinkDB All DBs Position 9:136945243..136946975 Genome browser AA seq 202 aa AA seqDB search MLPPGTATLLTLLLAAGSLGQKPQRPRRPASPISTIQPKANFDAQQFAGTWLLVAVGSAC RFLQEQGHRAEATTLHVAPQGTAMAVSTFRKLDGICWQVRQLYGDTGVLGRFLLQARDAR GAVHVVVAETDYQSFAVLYLERAGQLSVKLYARSLPVSDSVLSGFEQRVQEAHLTEDQIF YFPKYGFCEAADQFHVLDEVRR NT seq 609 nt NT seq  +upstreamnt  +downstreamnt atgctgccccctgggactgcgaccctcttgactctgctcctggcagctggctcgctgggc cagaagcctcagaggccacgccggcccgcatcccccatcagcaccatccagcccaaggcc aattttgatgctcagcagtttgcagggacctggctccttgtggctgtgggctccgcttgc cgtttcctgcaggagcagggccaccgggccgaggccaccacactgcatgtggctccccag ggcacagccatggctgtcagtaccttccgaaagctggatgggatctgctggcaggtgcgc cagctctatggagacacaggggtcctcggccgcttcctgcttcaagcccgagacgcccga ggggctgtgcacgtggttgtcgctgagaccgactaccagagtttcgctgtcctgtacctg gagcgggcggggcagctgtcagtgaagctctacgcccgctcgctccctgtgagcgactcg gtcctgagtgggtttgagcagcgggtccaggaggcccacctgactgaggaccagatcttc tacttccccaagtacggcttctgcgaggctgcagaccagttccacgtcctggacgaagtg aggaggtga

DBGET integrated database retrieval system