Homo sapiens (human): 7374
Help
Entry
7374 CDS
T01001
Symbol
UNG, DGU, HIGM4, HIGM5, UDG, UNG1, UNG15, UNG2
Name
(RefSeq) uracil DNA glycosylase
KO
K03648
uracil-DNA glycosylase [EC:
3.2.2.27
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03410
Base excision repair
hsa05340
Primary immunodeficiency
Network
nt06504
Base excision repair
Element
N01433
Base excision and strand cleavage by monofunctional glycosylase
Disease
H00086
Immunodeficiency with hyper-IgM
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09124 Replication and repair
03410 Base excision repair
7374 (UNG)
09160 Human Diseases
09163 Immune disease
05340 Primary immunodeficiency
7374 (UNG)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
hsa03400
]
7374 (UNG)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.2 Glycosylases
3.2.2 Hydrolysing N-glycosyl compounds
3.2.2.27 uracil-DNA glycosylase
7374 (UNG)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
DNA glycosylases
7374 (UNG)
Prokaryotic type
7374 (UNG)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
UDG
DUF7694
PTHB1_CtH
Motif
Other DBs
NCBI-GeneID:
7374
NCBI-ProteinID:
NP_550433
OMIM:
191525
HGNC:
12572
Ensembl:
ENSG00000076248
UniProt:
P13051
E5KTA5
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:109097597..109110992
Genome browser
AA seq
313 aa
AA seq
DB search
MIGQKTLYSFFSPSPARKRHAPSPEPAVQGTGVAGVPEESGDAAAIPAKKAPAGQEEPGT
PPSSPLSAEQLDRIQRNKAAALLRLAARNVPVGFGESWKKHLSGEFGKPYFIKLMGFVAE
ERKHYTVYPPPHQVFTWTQMCDIKDVKVVILGQDPYHGPNQAHGLCFSVQRPVPPPPSLE
NIYKELSTDIEDFVHPGHGDLSGWAKQGVLLLNAVLTVRAHQANSHKERGWEQFTDAVVS
WLNQNSNGLVFLLWGSYAQKKGSAIDRKRHHVLQTAHPSPLSVYRGFFGCRHFSKTNELL
QKSGKKPIDWKEL
NT seq
942 nt
NT seq
+upstream
nt +downstream
nt
atgatcggccagaagacgctctactcctttttctcccccagccccgccaggaagcgacac
gcccccagccccgagccggccgtccaggggaccggcgtggctggggtgcctgaggaaagc
ggagatgcggcggccatcccagccaagaaggccccggctgggcaggaggagcctgggacg
ccgccctcctcgccgctgagtgccgagcagttggaccggatccagaggaacaaggccgcg
gccctgctcagactcgcggcccgcaacgtgcccgtgggctttggagagagctggaagaag
cacctcagcggggagttcgggaaaccgtattttatcaagctaatgggatttgttgcagaa
gaaagaaagcattacactgtttatccacccccacaccaagtcttcacctggacccagatg
tgtgacataaaagatgtgaaggttgtcatcctgggacaggatccatatcatggacctaat
caagctcacgggctctgctttagtgttcaaaggcctgttccgcctccgcccagtttggag
aacatttataaagagttgtctacagacatagaggattttgttcatcctggccatggagat
ttatctgggtgggccaagcaaggtgttctccttctcaacgctgtcctcacggttcgtgcc
catcaagccaactctcataaggagcgaggctgggagcagttcactgatgcagttgtgtcc
tggctaaatcagaactcgaatggccttgttttcttgctctggggctcttatgctcagaag
aagggcagtgccattgataggaagcggcaccatgtactacagacggctcatccctcccct
ttgtcagtgtatagagggttctttggatgtagacacttttcaaagaccaatgagctgctg
cagaagtctggcaagaagcccattgactggaaggagctgtga
DBGET
integrated database retrieval system
