Homo sapiens (human): 83990
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Entry
83990 CDS
T01001
Symbol
BRIP1, BACH1, FANCJ, OF
Name
(RefSeq) BRCA1 interacting helicase 1
KO
K15362
fanconi anemia group J protein [EC:
5.6.2.3
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03440
Homologous recombination
hsa03460
Fanconi anemia pathway
Network
nt06508
Interstrand crosslink repair
Element
N01466
Homologous recombination in ICLR
Disease
H00031
Breast cancer
H00238
Fanconi anemia
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
83990 (BRIP1)
03460 Fanconi anemia pathway
83990 (BRIP1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
hsa03400
]
83990 (BRIP1)
Enzymes [BR:
hsa01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
83990 (BRIP1)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-B complex
83990 (BRIP1)
FA (Fanconi anemia) pathway
Downstream FA components
83990 (BRIP1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DEAD_2
Helicase_C_2
DEAD
ResIII
DUF4769
HBB
Motif
Other DBs
NCBI-GeneID:
83990
NCBI-ProteinID:
NP_114432
OMIM:
605882
HGNC:
20473
Ensembl:
ENSG00000136492
Pharos:
Q9BX63
(Tbio)
UniProt:
Q9BX63
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:complement(61679139..61863528)
Genome browser
AA seq
1249 aa
AA seq
DB search
MSSMWSEYTIGGVKIYFPYKAYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSA
LAWQQSLSGKPADEGVSEKAEVQLSCCCACHSKDFTNNDMNQGTSRHFNYPSTPPSERNG
TSSTCQDSPEKTTLAAKLSAKKQASIYRDENDDFQVEKKRIRPLETTQQIRKRHCFGTEV
HNLDAKVDSGKTVKLNSPLEKINSFSPQKPPGHCSRCCCSTKQGNSQESSNTIKKDHTGK
SKIPKIYFGTRTHKQIAQITRELRRTAYSGVPMTILSSRDHTCVHPEVVGNFNRNEKCME
LLDGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEELVSLGKKLKACPYYTARELIQ
DADIIFCPYNYLLDAQIRESMDLNLKEQVVILDEAHNIEDCARESASYSVTEVQLRFARD
ELDSMVNNNIRKKDHEPLRAVCCSLINWLEANAEYLVERDYESACKIWSGNEMLLTLHKM
GITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVPVISASTQIMLKGLFMVLDYLFRQ
NSRFADDYKIAIQQTYSWTNQIDISDKNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAF
SDINGKVQTIVLTSGTLSPMKSFSSELGVTFTIQLEANHIIKNSQVWVGTIGSGPKGRNL
CATFQNTETFEFQDEVGALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELV
KTVIVEPQGGEKTNFDELLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVI
TIGIPFPNVKDLQVELKRQYNDHHSKLRGLLPGRQWYEIQAYRALNQALGRCIRHRNDWG
ALILVDDRFRNNPSRYISGLSKWVRQQIQHHSTFESALESLAEFSKKHQKVLNVSIKDRT
NIQDNESTLEVTSLKYSTSPYLLEAASHLSPENFVEDEAKICVQELQCPKIITKNSPLPS
SIISRKEKNDPVFLEEAGKAEKIVISRSTSPTFNKQTKRVSWSSFNSLGQYFTGKIPKAT
PELGSSENSASSPPRFKTEKMESKTVLPFTDKCESSNLTVNTSFGSCPQSETIISSLKID
ATLTRKNHSEHPLCSEEALDPDIELSLVSEEDKQSTSNRDFETEAEDESIYFTPELYDPE
DTDEEKNDLAETDRGNRLANNSDCILAKDLFEIRTIKEVDSAREVKAEDCIDTKLNGILH
IEESKIDDIDGNVKTTWINELELGKTHEIEIKNFKPSPSKNKGMFPGFK
NT seq
3750 nt
NT seq
+upstream
nt +downstream
nt
atgtcttcaatgtggtctgaatatacaattggtggggtgaagatttactttccttataaa
gcttacccgtcacagcttgctatgatgaattctattctcagaggattaaacagcaagcaa
cattgtttgttggagagtcccacaggaagtggaaaaagcttagccttactttgttctgct
ttagcatggcaacaatctcttagtgggaaaccagcagatgagggcgtaagtgaaaaagct
gaagtacaattgtcatgttgttgtgcatgccattcaaaggattttacaaacaatgacatg
aaccaaggaacttcacgtcatttcaactatccaagcacaccaccttctgaaagaaatggc
acttcatcaacttgtcaagactcccctgaaaaaaccactctggctgcaaagttatctgct
aagaaacaggcatccatatacagagatgaaaatgatgattttcaagtagagaagaaaaga
attcgacccttagaaactacacagcagattagaaaacgtcattgctttggaacagaagta
cacaatttggatgcaaaagttgattcaggaaagactgtaaaactcaactctccactggaa
aagataaactccttttcgccacagaaaccccctggccactgttctaggtgctgttgttct
actaaacaaggaaacagtcaagagtcatcgaataccattaagaaggatcatacagggaaa
tccaagatacccaaaatatattttgggacacgcacacacaagcagattgctcagattact
agagagctccggaggacggcatattcaggggttccaatgactattctttccagcagggat
catacttgtgtccatcctgaggtagtcggtaacttcaacagaaatgagaagtgcatggaa
ttgctagatgggaaaaacggaaaatcctgctatttttatcatggagttcataaaattagt
gatcagcacacattacagactttccaagggatgtgcaaagcctgggatatagaagaactt
gtcagcctggggaagaaactaaaggcctgtccatattacacagcccgagaactaatacaa
gatgctgacatcatattttgtccctacaactatcttctagatgcacaaataagggaaagt
atggatttaaatctgaaagaacaggttgtcattttagatgaagctcataacatcgaggac
tgtgctcgggaatcagcaagttacagtgtaacagaagttcagcttcggtttgctcgggat
gaactagatagtatggtcaacaataatataaggaagaaagatcatgaacccctacgagct
gtgtgctgtagcctcattaattggttagaagcaaacgctgaatatcttgtagaaagagat
tatgaatcagcttgtaaaatatggagtggaaatgaaatgctcttaactttacacaaaatg
ggtatcaccactgctacttttcccattttgcagggacatttttctgctgttcttcaaaaa
gaggaaaaaatctcaccaatttatggtaaagaggaggcaagagaagtacctgttattagt
gcatcaactcaaataatgcttaaaggactttttatggtacttgactatctttttaggcaa
aatagcagatttgcagatgattataaaattgcgattcaacagacttactcctggacaaat
cagattgatatttcagacaaaaatgggttgttggttctaccaaaaaataagaaacgttca
cgacagaaaactgcagttcatgtgctaaacttttggtgcttaaatccagctgtggccttt
tcagatattaatggcaaagttcagaccattgttttgacatctggtacattatcaccaatg
aaatccttttcgtcagaacttggtgttacatttactatccagctggaggctaatcatatc
attaaaaattcacaggtttgggttggtaccattgggtcaggccccaagggtcggaatctc
tgtgctaccttccagaatactgaaacatttgagttccaagatgaagtgggagcacttttg
ttatctgtgtgccagactgtgagccaaggaattttgtgtttcttgccatcttacaagtta
ttagaaaaattaaaagaacgttggctctctactggtttatggcataatctggagttggtg
aagacagtcattgtagaaccacagggaggagaaaaaacaaattttgatgaattactgcag
gtgtactatgacgcaatcaaatacaaaggagagaaagatggagctctcctggtagcagtt
tgtcgtggtaaagtgagtgagggtctggatttctcagatgacaatgcccgtgctgtcata
acaataggaattccttttccaaatgtgaaagatctacaggttgaactaaaacgacaatac
aatgaccaccattcaaaattgagaggtcttctacctggccgtcagtggtatgaaattcaa
gcatacagggccttaaaccaggcccttggtagatgtattagacacagaaatgattgggga
gctcttattctagtggatgatcgctttaggaataacccaagtcgctatatatctggactt
tctaaatgggtacggcagcagattcagcaccattcaacctttgaaagtgcactggaatcc
ttggctgaattttccaaaaagcatcaaaaagttcttaatgtatccataaaggacagaacc
aatatacaggacaatgagtctacacttgaagtgacctctttaaagtacagtacctcacct
tatttactggaagcagcaagtcatctatcaccagaaaattttgtggaagatgaagcaaag
atatgtgtccaggaactacagtgtcctaaaattattaccaaaaattcacctctaccaagt
agcattatctccagaaaggagaaaaatgatccagtattcctggaagaagcagggaaagca
gaaaaaattgtgatttccagatccacaagcccaactttcaacaaacaaacaaagagagtt
agctggtcaagctttaattctttgggacagtattttactggtaaaataccgaaggcaaca
cctgagctcgggtcatcagagaatagtgcctctagtcctccccgtttcaaaacagagaag
atggaaagtaaaactgttttgcccttcactgataaatgtgaatcctcaaatctgacagta
aacacatcgtttggatcatgccctcaatcagaaaccattatttcatcattaaagattgat
gccacccttactagaaaaaatcattctgaacatccgctctgttctgaagaagccctggat
ccagacattgaattgtctctagtaagtgaagaagataaacagtccacttcaaatagagat
tttgaaacagaagcagaagatgaatctatctattttacacctgaactttatgatcctgaa
gatacagatgaagaaaaaaatgacctagctgaaactgatagaggaaatagattggctaac
aattcagattgcattttagctaaagacctttttgaaattagaactataaaagaagtagat
tcagccagagaagtgaaagctgaggattgcatagatacaaagttgaatggaattctgcat
attgaagaaagtaaaattgatgacattgatggtaatgtaaaaacaacttggataaatgaa
ctggaactgggaaaaactcatgaaatagaaataaagaactttaaaccatctccttccaaa
aataaaggcatgtttcctggttttaagtaa
DBGET
integrated database retrieval system